Influence of parietal cell vagotomy and selective gastric vagotomy on gastric emptying rate and serum gastrin concentration.

Abstract:

:Gastric emptying of a solid meal and serum gastrin concentration were studied in 26 patients with duodenal ulcer disease before and after parietal cell vagotomy (PCV), selective gastric vagotomy with drainage (SGV + D), or parietal cell vagotomy with drainage. PCV had no significant effect on gastric emptying rate, whereas emptying was significantly delayed after SGV + D. The integrated gastrin output 60 to 300 min after the test meal was insignificantly altered after PCV, but significantly increased after SGV + D. It is concluded that the drainage procedure did not normalize the disturbed gastric emptying after SGV. The prolonged hypergastrinemia period after food stimulation may reflect stasis.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Brandsborg O,Brandsborg M,Lovgreen NA,Mikkelsen K,Moller B,Rokkjaer M,Amdrup E

subject

Has Abstract

pub_date

1977-02-01 00:00:00

pages

212-4

issue

2

eissn

0016-5085

issn

1528-0012

pii

S0016508577000432

journal_volume

72

pub_type

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