Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Screening, Diagnosis, and Therapy.

abstract：:Intracellular microelectrodes were used to evaluate electrical properties of the cell membranes in Necturus antral mucosa during exposure to luminal acid alone (pH 4) or to 5 mmol/L aspirin [acetylsalicylic acid (ASA)] in the presence of luminal acid. When nutrient solutions were buffered by HCO3- (pH 7.3), ASA modera...

journal_title：Gastroenterology

authors： Soybel DI,Davis MB,West AB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanism by which gastric mucosa becomes more resistant to damage by repeated aspirin administration is not known. Transforming growth factor alpha (TGF-alpha) and epidermal growth factor (EGF) prevent drug-induced gastric injury. The aim of this study was to determine whether gastroduodenal tiss...

journal_title：Gastroenterology

authors： Romano M,Lesch CA,Meise KS,Veljaca M,Sanchez B,Kraus ER,Boland CR,Guglietta A,Coffey RJ

更新日期：1996-05-01 00:00:00

abstract：:Fever of 10 mo duration in a man of 35 yr was discovered at the time of a second laparatomy to be caused by actinomycotic infection of the liver. Actinomycosis of the liver usually presents as large single or as multiple abscesses. In this patient only nonspecific cellular infiltrates of the liver were found in liver ...

journal_title：Gastroenterology

authors： Meade RH 3rd

更新日期：1980-02-01 00:00:00

abstract：:In rats injected with pentagastrin (2-500 micrograms/kg subcutaneously) in saline, peak gastric acid responses occurred after 31 (30-min output) or 63 micrograms/kg (60-min output). Rats were fed or fasted for 48 h and injected every 8 h with 63, 250, or 1000 micrograms/kg pentagastrin. Fasting decreased body weight (...

journal_title：Gastroenterology

authors： Solomon TE

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND & AIMS:The relationship between the sensation of bloating, often ranked as the most bothersome symptom by patients with irritable bowel syndrome (IBS), and actual distention manifest as an increase in abdominal girth is controversial. Investigation of this problem has been hampered by the lack of a reliable ...

journal_title：Gastroenterology

authors： Houghton LA,Lea R,Agrawal A,Reilly B,Whorwell PJ

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND & AIMS:Agents designed to block or alter cytokinesis can kill or stop proliferation of cancer cells. We aimed to identify cytokinesis-related proteins that are overexpressed in hepatocellular carcinoma (HCC) cells and might be targeted to slow liver tumor growth. METHODS:Using the Oncomine database, we comp...

journal_title：Gastroenterology

authors： Yang XM,Cao XY,He P,Li J,Feng MX,Zhang YL,Zhang XL,Wang YH,Yang Q,Zhu L,Nie HZ,Jiang SH,Tian GA,Zhang XX,Liu Q,Ji J,Zhu X,Xia Q,Zhang ZG

更新日期：2018-10-01 00:00:00

abstract：:Ornithine decarboxylase activity is known to be increased in certain premalignant conditions. We determined the activity of this enzyme in mucosal biopsy specimens from 15 patients with Barrett's esophagus. Ornithine decarboxylase was greater in Barrett's mucosa than in squamous esophageal or gastric mucosa. In Barret...

journal_title：Gastroenterology

authors： Garewal HS,Sampliner R,Gerner E,Steinbronn K,Alberts D,Kendall D

更新日期：1988-03-01 00:00:00

abstract：:Helicobacter pylori has recently been implicated as an etiologic agent of gastroduodenal disorders. Comparing the antibody to H. pylori in the sera of patients with that of normal controls by Western blot analysis, a unique antibody was detected in the sera of patients, which reacted with the 25-kilodalton antigen of ...

journal_title：Gastroenterology

authors： Sugiyama T,Imai K,Yoshida H,Takayama Y,Yabana T,Yokota K,Oguma K,Yachi A

更新日期：1991-07-01 00:00:00

abstract：:The results of a clinical trial comparing slow-release 5-aminosalicylic acid tablets (Pentasa) and enteric-coated sulfasalazine tablets (Salazopyrin) with regard to the efficacy of maintaining ulcerative colitis patients in remission for 12 mo and with regard to safety of treatment are reported. Seventy-five patients ...

journal_title：Gastroenterology

authors： Mulder CJ,Tytgat GN,Weterman IT,Dekker W,Blok P,Schrijver M,van der Heide H

更新日期：1988-12-01 00:00:00

abstract：:Increased dietary ratios of ω6/ω3 polyunsaturated fatty acids have been implicated in the pathogenesis of Crohn's disease (CD), but epidemiologic data are limited. We investigated whether variants of genes that control polyunsaturated fatty acid metabolism (CYP4F3, FADS1, and FADS2), along with the dietary ratio of ω6...

journal_title：Gastroenterology

authors： Costea I,Mack DR,Lemaitre RN,Israel D,Marcil V,Ahmad A,Amre DK

更新日期：2014-04-01 00:00:00

abstract：:We describe the clinical and laboratory features of a case of spontaneous bacterial peritonitis caused by Neisseria gonorrhoeae in a sexually active woman with Laennec's cirrhosis, ascites, and asymptomatic cervical gonorrhea. Treatment of the infection with high-dose parenteral penicillin was associated with resoluti...

journal_title：Gastroenterology

authors： Stassen WN,McCullough AJ,Hilton PK

更新日期：1985-03-01 00:00:00

abstract：:Three cases of Stevens-Johnson syndrome with intestinal involvement are described. Two patients had esophageal involvement, the severity of which paralleled skin lesions and, in 1 case, probably contributed to death. Dysphagia and bleeding were manifestations. The third patient was unique and had gastric, small and la...

journal_title：Gastroenterology

authors： Zweiban B,Cohen H,Chandrasoma P

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND & AIMS:Oral bile acid replacement has been shown to be an effective therapy in primary bile acid synthesis defects, but to date there have been no reports of the long-term effects of this therapy. The aim of the study was to evaluate the long-term effectiveness and safety of cholic acid (CA) therapy. METHOD...

journal_title：Gastroenterology

authors： Gonzales E,Gerhardt MF,Fabre M,Setchell KD,Davit-Spraul A,Vincent I,Heubi JE,Bernard O,Jacquemin E

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Autoimmune responses against colonic epithelium may play a role in the development of colonic inflammation associated with ulcerative colitis (UC). In this study, we established and characterized B-cell lines and clones that produced anticolon antibody from inflamed colonic mucosa of UC subjects. M...

journal_title：Gastroenterology

authors： Inoue N,Watanabe M,Sato T,Okazawa A,Yamazaki M,Kanai T,Ogata H,Iwao Y,Ishii H,Hibi T

更新日期：2001-07-01 00:00:00

abstract：:The polypeptide core of mucin glycoprotein subunits resists cleavage by proteases. To determine if the carbohydrate side chains of these subunits protect the underlying polypeptide core from proteolytic cleavage, we compared the effect of pancreatic proteases on hog gastric mucin before and after cleavage of its carbo...

journal_title：Gastroenterology

authors： Variyam EP,Hoskins LC

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatic iron toxicity may be mediated by free radical species and lipid peroxidation of biological membranes. The antioxidant property of silybin, a main constituent of natural flavonoids, was investigated in vivo during experimental iron overload. METHODS:Rats were fed a 2.5% carbonyl-iron diet and ...

journal_title：Gastroenterology

authors： Pietrangelo A,Borella F,Casalgrandi G,Montosi G,Ceccarelli D,Gallesi D,Giovannini F,Gasparetto A,Masini A

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic hepatitis C virus (HCV) infection is a major burden on individuals and health care systems. The Extension for Community Healthcare Outcomes (Project ECHO) enables primary care providers to deliver best-practice care for complex conditions to underserved populations. The US Congress passed the ...

journal_title：Gastroenterology

authors： Rattay T,Dumont IP,Heinzow HS,Hutton DW

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND & AIMS:The majority of patients with Helicobacter pylori infection have autoantibodies cross-reacting with gastric antigens. In this study, the relation between autoantibody status, histopathology of body mucosa, and antigenic profile of H. pylori was investigated. METHODS:One hundred patients were examined...

journal_title：Gastroenterology

authors： Negrini R,Savio A,Poiesi C,Appelmelk BJ,Buffoli F,Paterlini A,Cesari P,Graffeo M,Vaira D,Franzin G

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND & AIMS:Helicobacter pylori infection is mainly acquired in early childhood, but the exact routes of transmission remain elusive. To distinguish between risks of intrafamilial and extraneous child-to-child transmission, we studied H. pylori seroprevalence among Swedish school children with varying family back...

journal_title：Gastroenterology

authors： Tindberg Y,Bengtsson C,Granath F,Blennow M,Nyrén O,Granström M

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately 10% of children on the liver transplant wait-list in the United States die every year. We examined deceased donor liver offer acceptance patterns and their contribution to pediatric wait-list mortality. METHODS:We performed a retrospective cohort study of children on the US liver transp...

journal_title：Gastroenterology

authors： Hsu EK,Shaffer ML,Gao L,Sonnenday C,Volk ML,Bucuvalas J,Lai JC

更新日期：2017-10-01 00:00:00

abstract：:To understand the disorders of bowel motility, it is important to know the range of bowel patterns in the general population. We have devised a brief self-administered questionnaire which, when used among a group of 789 students and hospital employees, disclosed that 94.2% had stool frequencies between three per day a...

journal_title：Gastroenterology

authors： Drossman DA,Sandler RS,McKee DC,Lovitz AJ

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND/AIMS:Human colonic epithelium produces large amounts of mucin. The aim of this study was to examine mucin biosynthesis in the human colon. METHODS:Human colonic mucin was isolated using CsCl density gradients, and polyclonal antiserum was raised. Biosynthesis of colonic mucins was studied by labeling coloni...

journal_title：Gastroenterology

authors： Tytgat KM,Büller HA,Opdam FJ,Kim YS,Einerhand AW,Dekker J

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal microbes induce homeostatic mucosal immune responses, but can also cause inappropriate immune activation in genetically susceptible hosts. Although immune responses to bacterial products have been studied extensively, little is known about how intestinal inflammation affects functions of co...

journal_title：Gastroenterology

authors： Patwa LG,Fan TJ,Tchaptchet S,Liu Y,Lussier YA,Sartor RB,Hansen JJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND & AIMS:Administration of secretin improves noninvasive imaging of the pancreatic duct with magnetic resonance cholangiopancreatography (MRCP). We performed a large prospective study to investigate whether synthetic human secretin (RG1068)-stimulated MRCP detects pancreatic duct abnormalities with higher leve...

journal_title：Gastroenterology

authors： Sherman S,Freeman ML,Tarnasky PR,Wilcox CM,Kulkarni A,Aisen AM,Jacoby D,Kozarek RA

更新日期：2014-09-01 00:00:00

abstract：:Polycystic liver diseases (PLD) are inherited disorders of the biliary epithelium, caused by genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic reticulum and the cilium. PLD are characterized by the formation and progressive enlargement of multiple cysts scattered throughout t...

journal_title：Gastroenterology

authors： Strazzabosco M,Somlo S

更新日期：2011-06-01 00:00:00

abstract：:Twenty-one of 52 patients with regional enteritis had low serum zinc concentrations on initial testing. Fourteen of 31 patients followed longitudinally had low serum zinc concentrations. Two patients are presented as case reports who developed acrodermatitis skin lesions that responded to zinc therapy. Hypogonadism, g...

journal_title：Gastroenterology

authors： McClain C,Soutor C,Zieve L

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Capsaicin-sensitive neurons contain various peptides including calcitonin gene-related peptide. This study examines (1) whether calcitonin gene-related peptide is involved in capsaicin-induced gastroprotection and (2) whether nitric oxide and prostaglandin are required for calcitonin gene-related peptide to ...

journal_title：Gastroenterology

authors： Lambrecht N,Burchert M,Respondek M,Müller KM,Peskar BM

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatitis G virus (HGV) has been recently identified as a new transfusion-transmissible agent. This study was performed to evaluate the role of HGV infection in patients with acute posttransfusion hepatitis in Taiwan. METHODS:Sera from 63 patients with acute posttransfusion hepatitis and 61 patients ...

journal_title：Gastroenterology

authors： Hwang SJ,Lu RH,Chan CY,Wang YJ,Wu JC,Lee SD

更新日期：1997-04-01 00:00:00

abstract：:Plasma levels of gastrinlike, somatostatinlike, and cholecystokininlike immunoreactivity were determined by radioimmunoassay in peripheral blood from 11 beagles during pregnancy and in response to suckling during lactation. Cholecystokinin was determined in pooled and in individual plasma samples after separation of c...

journal_title：Gastroenterology

authors： Linden A,Eriksson M,Carlquist M,Uvnäs-Moberg K

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND/AIMS:Recent in vivo studies using proton magnetic resonance (1H-MR) spectroscopy showed low levels of myo-inositol in the brain in hepatic encephalopathy; the pathogenetic relevance of this observation is unclear. METHODS:Myo-inositol and glutamine levels in the brain were studied in vivo by 1H-MR spectrosc...

journal_title：Gastroenterology

authors： Häussinger D,Laubenberger J,vom Dahl S,Ernst T,Bayer S,Langer M,Gerok W,Hennig J

更新日期：1994-11-01 00:00:00