Abstract:
:The association between parity and hepatocellular carcinoma (HCC) was studied using a data-base generated by linking 2 Swedish nation-wide registries; the Cancer Registry and the Fertility Registry. Among women born between 1925 and 1960, 133 patients with HCC recorded in the Cancer Registry between 1958 and 1984 were compared with 665 age-matched controls. In this nested case-control study there was no positive association between parity, age at first birth or frequency of twinning on the one hand, and risk of HCC on the other. It appears that the positive association between parity and HCC previously reported is limited to cases of HCC caused by chronic infection with hepatitis B virus; these cases represent only a small fraction of HCC cases in Sweden.
journal_name
Int J Cancerjournal_title
International journal of cancerauthors
Lambe M,Trichopoulos D,Hsieh CC,Ekbom A,Pavia Mdoi
10.1002/ijc.2910550508subject
Has Abstractpub_date
1993-11-11 00:00:00pages
745-7issue
5eissn
0020-7136issn
1097-0215journal_volume
55pub_type
杂志文章abstract::We examined the geospatial dimension of delays to diagnosis of breast cancer in a prospective study of 1541 women newly diagnosed in the African Breast Cancer - Disparities in Outcomes (ABC-DO) Study. Women were recruited at cancer treatment facilities in Namibia, Nigeria, Uganda, and Zambia. The baseline interview in...
journal_title:International journal of cancer
pub_type: 杂志文章
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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更新日期:1999-01-29 00:00:00
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journal_title:International journal of cancer
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更新日期:2003-02-10 00:00:00
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journal_title:International journal of cancer
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doi:10.1002/ijc.22839
更新日期:2007-09-15 00:00:00
abstract::Loss of heterozygosity (LOH) on 10q is associated with late-stage events in urothelial neoplastic progression. The tumor suppressor gene PTEN, which is mutated or homozygously deleted in numerous cancers, maps to a region of 10q within the reported region of minimal loss in bladder tumors. In two recent studies altera...
journal_title:International journal of cancer
pub_type: 杂志文章
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更新日期:2000-11-15 00:00:00
abstract::We have employed the DNA-mediated gene transfer method to introduce the allogenic major-histocompatibility-complex(MHC)-class-I gene H-2Kb into the K36.16 tumor cells, H-2k, in order to generate tumor-specific immunity. The acquisition of immunogenicity by the H-2Kb-transformed clones following gene transfer is associ...
journal_title:International journal of cancer
pub_type: 杂志文章
doi:10.1002/ijc.2910570215
更新日期:1994-04-15 00:00:00
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journal_title:International journal of cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0215(19960301)65:5<671::AID-IJC
更新日期:1996-03-01 00:00:00
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journal_title:International journal of cancer
pub_type: 杂志文章
doi:10.1002/ijc.2910540618
更新日期:1993-07-30 00:00:00
abstract::MaTu is a novel agent which may be of relevance in human oncogenesis, and has 2 components. One of them, the exogenous MX (coding for protein p58X), is transmissible to human fibroblasts, to HeLa and to HeLa x fibroblast (H/F) hybrids. The other component, MN, is a cellular gene. Its product, the protein p54/58N, is i...
journal_title:International journal of cancer
pub_type: 杂志文章
doi:10.1002/ijc.2910540218
更新日期:1993-05-08 00:00:00
abstract::The stability of expression of a membrane antigen on human FME melanoma cells was investigated by means of flow cytometric cell sorting and analysis. The melanoma-associated 250 kd antigen was strongly expressed on all cells, as recognized by binding of the monoclonal antibody 9.2.27. By flow cytometric cell sorting, ...
journal_title:International journal of cancer
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doi:10.1002/ijc.2910340413
更新日期:1984-10-15 00:00:00
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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journal_title:International journal of cancer
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更新日期:2002-05-20 00:00:00
abstract::Chemokines and chemokine receptors mediate lymphocyte migration and tissue localization. To analyze CCL5 (RANTES) expression by EBV-infected cells, we examined the expression of CCL5 in BL cell lines. Among 4 BL cell lines, those infected with EBV selectively expressed the CCL5 gene and secreted CCL5. Four cell lines ...
journal_title:International journal of cancer
pub_type: 杂志文章,收录出版
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更新日期:2005-05-01 00:00:00
abstract::This study was aimed at comparing screen-detected and symptomatic breast carcinomas with regard to the prevalence of positive immunostaining for c-erb-B-2 oncoprotein. Paraffin sections of 81 breast carcinomas detected through the National Screening Programme were examined for the over-expression of c-erbB-2 oncoprote...
journal_title:International journal of cancer
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更新日期:1993-08-19 00:00:00
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journal_title:International journal of cancer
pub_type: 杂志文章,评审
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更新日期:2010-10-15 00:00:00
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journal_title:International journal of cancer
pub_type: 杂志文章
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更新日期:2019-07-15 00:00:00
abstract::A population-based case-control study of gastric cancer was conducted in areas with contrasting incidence rates in Sweden. Face-to-face interviews were carried out with 338 (74.1%) of all eligible cases and 679 (77.3%) of the selected controls. Consumption of selected nutrients during adolescence and 20 years prior to...
journal_title:International journal of cancer
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doi:10.1002/ijc.2910570505
更新日期:1994-06-01 00:00:00
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journal_title:International journal of cancer
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更新日期:2005-11-01 00:00:00
abstract::The effect of cyclic phosphatidic acid, a unique analogue of lysophosphatidic acid, on the induction of bombesin-enhanced peritoneal metastases from intestinal adenocarcinomas induced by azoxymethane was investigated in male Wistar rats. Rats were given 10 weekly injections of azoxymethane (7.4 mg/kg body weight, s.c....
journal_title:International journal of cancer
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更新日期:2004-06-10 00:00:00
abstract::A series of 39 human brain tumors has been screened for the presence or absence of SV40-related T antigen by the direct and indirect immunoperoxidase methods. Two tumors of ependymal origin (malignant ependymoma, choroid plexus papilloma) revealed markedly positive nuclear staining for T antigen both in vivo and in vi...
journal_title:International journal of cancer
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更新日期:1978-01-15 00:00:00