Characterization of a small-cell-lung-carcinoma cell line from a patient with cancer-associated retinopathy.

abstract：:This study profiles testicular cancer incidence and mortality across Europe, and the effects of age, period and generational influences, using age-period-cohort modeling. Despite a 5-fold variation in incidence rates, there were consistent mean increases in incidence in each of the 12 European countries studied, rangi...

journal_title：International journal of cancer

authors： Bray F,Richiardi L,Ekbom A,Pukkala E,Cuninkova M,Møller H

更新日期：2006-06-15 00:00:00

abstract：:A cytogenetic study, including prophase-prometaphase chromosome analysis, of a patient with EBV-genome-negative acute lymphocytic leukemia of B-cell type with Burkitt-type cells is presented. All bone-marrow mitoses examined had a 14q+ marker chromosome which was identified as a reciprocal 8;14 translocation of exactl...

journal_title：International journal of cancer

authors： Mitelman F,Andersson-Anvret M,Brandt L,Catovsky D,Klein G,Manolov G,Manolova Y,Mark-Vendel E,Nilsson PG

更新日期：1979-07-15 00:00:00

abstract：:The following studies were undertaken to determine the levels of serum carotene and vitamin A (retinol) in Egyptian patients with intestinal, urinary, hepatosplenic schistosomiasis, and bladder cancer. These studies have shown that both serum carotene and serum retinol levels are significantly reduced in patients with...

journal_title：International journal of cancer

authors： Mahmoud LA,Robinson WA

更新日期：1982-08-15 00:00:00

abstract：:The FUS-CHOP fusion protein has been found to be instrumental for specific oncogenic processes in liposarcoma, but its ability to induce metastasis and the underlying mechanisms by which this can be achieved remain unknown. To dissect its functional role in this context, we stably overexpressed this protein in SW872 l...

journal_title：International journal of cancer

authors： Patil N,Ahmed Kabeer Rasheed S,Abba M,Hendrik Leupold J,Schwarzbach M,Allgayer H

更新日期：2014-06-15 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChR) are expressed on bronchial epithelial and non-small cell lung cancer cells and are involved in cell growth regulation. Nicotine (classical nAChR agonist) induced cell proliferation, whereas nAChR antagonists, d- tubocurarine or alpha-cobratoxin (alpha-CbT), induced cell death....

journal_title：International journal of cancer

authors： Paleari L,Sessa F,Catassi A,Servent D,Mourier G,Doria-Miglietta G,Ognio E,Cilli M,Dominioni L,Paolucci M,Calcaterra A,Cesario A,Margaritora S,Granone P,Russo P

更新日期：2009-07-01 00:00:00

abstract：:Markers of exposure to polycyclic aromatic hydrocarbons (urinary 1-hydroxypyrene-glucuronide) and aromatic amines (4-aminobiphenyl-hemoglobin adducts), as well as urinary mutagenicity, were measured in 47 healthy smokers and 50 nonsmokers. DNA adducts were determined by P32-postlabeling in the exfoliated bladder cells...

journal_title：International journal of cancer

authors： Vineis P,Talaska G,Malaveille C,Bartsch H,Martone T,Sithisarankul P,Strickland P

更新日期：1996-01-26 00:00:00

abstract：:Therapeutics targeting the phosphatidylinositol 3-kinase/mammalian target of rapamycin (PI3K/mTOR) pathway initially produce potent antitumor effects, but resistance frequently occurs. Using a phosphoproteome analysis, we found that colorectal cancer (CRC) cells exhibit resistance against PI3K/mTOR inhibition through ...

journal_title：International journal of cancer

authors： Lee HS,Lee S,Cho KH

更新日期：2020-11-15 00:00:00

abstract：:Knowledge about the prevalence of human papillomavirus (HPV) on a population level is important. We conducted a large population-based study in Denmark to determine the overall and age-specific HPV prevalence, and HPV type distribution in women. Liquid-based cytology samples (SurePath) were collected consecutively. HP...

journal_title：International journal of cancer

authors： Kjaer SK,Breugelmans G,Munk C,Junge J,Watson M,Iftner T

更新日期：2008-10-15 00:00:00

abstract：:Annamycin (Ann) is a non-cross-resistant lipophilic anthracycline antiobiotic optimally suited for liposome delivery. We studied how vesicle size and presence of phospholipids with a high phase transition temperature and monosialoganglioside (GM I) in the liposome bilayers affect the pharmacokinetics, tumor selectivit...

journal_title：International journal of cancer

authors： Zou Y,Ling YH,Reddy S,Priebe W,Perez-Soler R

更新日期：1995-05-29 00:00:00

abstract：:The murine B16 melanoma (H-2b) was transfected with a retroviral vector containing the mouse IFN-alpha 1 gene. IFN-alpha 1-transfected cells produced IFN-alpha in vitro and exhibited an altered phenotype characterized by a decreased rate of multiplication, enhanced expression of H-2 antigens, an antiviral state to VSV...

journal_title：International journal of cancer

authors： Kaido T,Bandu MT,Maury C,Ferrantini M,Belardelli F,Gresser I

更新日期：1995-01-17 00:00:00

abstract：:We evaluated the associations of such lifestyle factors as alcohol drinking, coffee consumption and medical history with risk of death from pancreatic cancer in a large-scale prospective cohort study [the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC study)] in Japan. Subjects were 110,792 (46,4...

journal_title：International journal of cancer

authors： Lin Y,Tamakoshi A,Kawamura T,Inaba Y,Kikuchi S,Motohashi Y,Kurosawa M,Ohno Y

更新日期：2002-06-10 00:00:00

abstract：:The occurrence of resistance to cytotoxic agents in tumor cells, associated with several phenotypic alterations, is one of the major obstacles to successful anticancer chemotherapy. A new strategy to overcome MDR of human cancer cells was studied, using BSAO, which generates cytotoxic products from spermine, H(2)O(2) ...

journal_title：International journal of cancer

authors： Calcabrini A,Arancia G,Marra M,Crateri P,Befani O,Martone A,Agostinelli E

更新日期：2002-05-01 00:00:00

abstract：:In order to study the mechanisms responsible for resistance to CDDP, 5 human tumor cell lines were made resistant to CDDP by repeated in vitro exposures. After cloning it was found that the cell lines developed were between 3.3-fold and 17-fold more resistant to CDDP than the parental cell lines at the IC90. These lin...

journal_title：International journal of cancer

authors： Teicher BA,Holden SA,Herman TS,Sotomayor EA,Khandekar V,Rosbe KW,Brann TW,Korbut TT,Frei E 3rd

更新日期：1991-01-21 00:00:00

abstract：:There are few published estimates of the risk of developing breast or ovarian cancer in women with a strong family history of ovarian cancer. As these women commonly present to family cancer clinics, accurate cancer risk estimates are needed. We have estimated these risks in women from families with 2 or more confirme...

journal_title：International journal of cancer

authors： Sutcliffe S,Pharoah PD,Easton DF,Ponder BA

更新日期：2000-07-01 00:00:00

abstract：:Macrophages were isolated from 22 human ascitic ovarian epithelial tumors and their growth-inhibitory capacity was tested using as targets the following in vitro tumor cell lines: murine TLX9 lymphoma and FS6 sarcoma; human myeloid K562 leukemia and human E cell line derived from an ovarian carcinoma. Macrophage prepa...

journal_title：International journal of cancer

authors： Mantovani A,Peri G,Polentarutti N,Bolis G,Mangioni C,Spreafico F

更新日期：1979-02-01 00:00:00

abstract：:Over 10% of children with Wilms tumor (WT) have an underlying cancer predisposition syndrome (CPS). Cognizant of increasing demand for genetic evaluation and limited resources across health care settings, there is an urgent need to rationalize genetic referrals for this population. The McGill Interactive Pediatric Onc...

journal_title：International journal of cancer

authors： Cullinan N,Villani A,Mourad S,Somers GR,Reichman L,van Engelen K,Stephens D,Weksberg R,Foulkes WD,Malkin D,Grant R,Goudie C

更新日期：2020-02-15 00:00:00

abstract：:Duodenogastric reflux (DGR) causes glandular stomach carcinogenesis in rats without carcinogens. We aimed to investigate how this carcinogenesis might be prevented by a selective COX-2 inhibitor, meloxicam. A series of 188 Fisher 344 rats underwent a surgical DGR procedure and were divided into 2 groups. One group was...

journal_title：International journal of cancer

authors： Oba M,Miwa K,Fujimura T,Harada S,Sasaki S,Hattori T

更新日期：2008-10-01 00:00:00

abstract：:The diagnostic specificity of the detection of disseminated prostatic cells by reverse-transcriptase polymerase chain reaction (RT-PCR) of PSA mRNA was investigated. A sensitive nested PCR was developed. In blood samples from 10 healthy female and 10 healthy male persons examined by RT-PCR, mRNA of PSA was detected 3 ...

journal_title：International journal of cancer

authors： Henke W,Jung M,Jung K,Lein M,Schlechte H,Berndt C,Rudolph B,Schnorr D,Loening SA

更新日期：1997-01-06 00:00:00

abstract：:The findings of mutations and the development of targeted therapies have improved lung cancer management. Still, the prognosis remains poor, and we need to know more about the genetic and epigenetic alterations in lung cancer. MicroRNAs are involved in crucial biological processes like carcinogenesis by regulating gen...

journal_title：International journal of cancer

authors： Bjaanaes MM,Halvorsen AR,Solberg S,Jørgensen L,Dragani TA,Galvan A,Colombo F,Anderlini M,Pastorino U,Kure E,Børresen-Dale AL,Brustugun OT,Helland A

更新日期：2014-10-15 00:00:00

abstract：:Lysine-specific demethylase 1 (LSD1), a histone lysine demethylase with the main specificity for H3K4me2, has been shown to be overexpressed in rhabdomyosarcoma (RMS) tumor samples. However, its role in RMS biology is not yet well understood. Here, we identified a new role of LSD1 in regulating adhesion of RMS cells. ...

journal_title：International journal of cancer

authors： Haydn T,Kehr S,Willmann D,Metzger E,Schüle R,Fulda S

更新日期：2020-06-15 00:00:00

abstract：:In our study, we aimed to investigate the expression of N-cadherin and E-cadherin and their dependency on epithelial-mesenchymal transition regulators SNAI1, SIP1 and TWIST in human colon cancer. Expression of E-cadherin and N-cadherin was examined by immunohistochemistry in 80 colon carcinomas by using paraffin embed...

journal_title：International journal of cancer

authors： Rosivatz E,Becker I,Bamba M,Schott C,Diebold J,Mayr D,Höfler H,Becker KF

更新日期：2004-09-20 00:00:00

abstract：:Cytokines such as Interleukin (IL)-12p70 ("IL-12") and IL-23 can influence tumor progression. We tested the hypothesis that blood levels of IL-12p40, the common subunit of both cytokines, are associated with melanoma progression. Blood from 2,048 white melanoma patients were collected at a single institution between M...

journal_title：International journal of cancer

authors： Fang S,Wang Y,Chun YS,Liu H,Ross MI,Gershenwald JE,Cormier JN,Royal RE,Lucci A,Schacherer CW,Reveille JD,Sui D,Bassett RL Jr,Wang LE,Wei Q,Amos CI,Lee JE

更新日期：2015-04-15 00:00:00

abstract：:In children, renal cell carcinoma (RCC) is rare. This study is the first report of pediatric patients with RCC registered by the International Society of Pediatric Oncology-Renal Tumor Study Group (SIOP-RTSG). Pediatric patients with histologically confirmed RCC, registered in SIOP 93-01, 2001 and UK-IMPORT databases,...

journal_title：International journal of cancer

authors： van der Beek JN,Hol JA,Coulomb-l'Hermine A,Graf N,van Tinteren H,Pritchard-Jones K,Houwing ME,de Krijger RR,Vujanic GM,Dzhuma K,Schenk JP,Littooij AS,Ramírez-Villar GL,Murphy D,Ray S,Al-Saadi R,Gessler M,Godzinski J,R

更新日期：2021-01-18 00:00:00

abstract：:We have developed novel 3-dimensional in vitro and in vivo tissue models that mimic premalignant disease of human stratified epithelium in order to analyze the stromal contribution of extracellular matrix and basement membrane proteins to the progression of intraepithelial neoplasia. Three-dimensional, organotypic cul...

journal_title：International journal of cancer

authors： Andriani F,Garfield J,Fusenig NE,Garlick JA

更新日期：2004-01-20 00:00:00

abstract：:Recently reported genome-wide association studies have identified more than 20 common low-penetrance colorectal cancer (CRC) susceptibility loci. Recent studies have reported that copy number variations (CNVs) are considered important human genomic variants related to cancer, while the contribution of CNVs remains unc...

journal_title：International journal of cancer

authors： Park C,Kim JI,Hong SN,Jung HM,Kim TJ,Lee S,Kim SJ,Kim HC,Kim DH,Cho B,Park JH,Sung J,Lee DS,Kang M,Son HJ,Kim YH

更新日期：2017-01-01 00:00:00

abstract：:Although in the normal healthy organism angiogenesis is a tightly regulated process, under a variety of circumstances it may contribute to disease states. These include the growth of solid tumors, the hematogenous spread of tumor cells and the growth of metastasis. Our aim was to measure the levels of 5 angiogenic cyt...

journal_title：International journal of cancer

authors： Fuhrmann-Benzakein E,Ma MN,Rubbia-Brandt L,Mentha G,Ruefenacht D,Sappino AP,Pepper MS

更新日期：2000-01-01 00:00:00

abstract：:The Swedish Family-Cancer Database was used to analyze familial relationships in mothers and daughters in invasive and in situ cervical cancers from years 1958-1994, including a total of 125,000 in situ and 14,000 invasive cancers. In situ cancers were diagnosed on average 10 years earlier than invasive cancers. Famil...

journal_title：International journal of cancer

authors： Hemminki K,Dong C,Vaittinen P

更新日期：1999-09-09 00:00:00

abstract：:The c-KIT protooncogene encodes a tyrosine kinase receptor, KIT, that is expressed in many normal and cancerous tissues. In this study, we have examined the expression of c-KIT and its ligand, stem cell factor (SCF), in human epithelial ovarian tumors, in normal ovaries and in cultured ovarian surface epithelium (OSE)...

journal_title：International journal of cancer

authors： Tonary AM,Macdonald EA,Faught W,Senterman MK,Vanderhyden BC

更新日期：2000-05-20 00:00:00

abstract：:In Japan, cervical cancer incidence has increased since the late 1990s especially among young women, despite a decreasing trend in most developed countries. Here, we examined age, period and birth cohort trends in cervical cancer incidence rates from 1985 to 2012. Incidence rates were ascertained using three populatio...

journal_title：International journal of cancer

authors： Utada M,Chernyavskiy P,Lee WJ,Franceschi S,Sauvaget C,de Gonzalez AB,Withrow DR

更新日期：2019-05-01 00:00:00

abstract：:Ferric nitrilotriacetate (Fe-NTA) causes renal proximal tubular necrosis, a consequence of iron ion-mediated free-radical-associated damage, that finally leads to a high incidence of renal adenocarcinoma in male rats and mice. We have investigated the levels of typical hydroxyl radical-induced DNA base modifications i...

journal_title：International journal of cancer

authors： Toyokuni S,Mori T,Dizdaroglu M

更新日期：1994-04-01 00:00:00