Rapid assessment of protein-tyrosine phosphatase expression levels by RT-PCR with degenerate primers.

abstract：:Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. Direct exposure of human hepatoma cell line SMMC-7221 to hydrogen peroxide (H2O2) can induce apoptosis characterized by morphological evidence and fragmentation of DNA assayed by terminal deoxynucleotidyl transferase ...

journal_title：Molecular biology reports

authors： Huang C,Li J,Zheng R,Cui K

更新日期：2000-03-01 00:00:00

abstract：:C2H2 proteins belong to a group of transcription factors (TFs) existing as a superfamily that plays important roles in defense responses and various other physiological processes in plants. The present study aimed to screen for and identify C2H2 proteins associated with defense responses to abiotic and biotic stresses...

journal_title：Molecular biology reports

authors： Jiang L,Pan LJ

更新日期：2012-06-01 00:00:00

abstract：:The potential benefiting effects of probiotic Dahi on age-inflicted accumulation of oxidation products, antioxidant enzymes and expression of biomarkers of ageing were evaluated in mice. Probiotic Dahi were prepared by co-culturing in buffalo milk (3% fat) Dahi bacteria (Lactococcus lactis ssp. cremoris NCDC-86 and La...

journal_title：Molecular biology reports

authors： Kaushal D,Kansal VK

更新日期：2012-02-01 00:00:00

abstract：:The programmed cell death (PCD) is important in maintaining the cell number homoeostasis of tissues and organs in metazoan. This process is regulated by the inhibitors of apoptosis proteins (IAPs). The function and mechanism of IAPs have been well studied in animal embryonic development and human cancers. However, the...

journal_title：Molecular biology reports

authors： He HJ,Hou L,Wang JX,Zhao XF

更新日期：2012-02-01 00:00:00

abstract：:Stomatal closure is a common adaptation response of plants to the onset of drought condition and its regulation is controlled by transcription factors. MYB60, a transcription factor involved in the regulation of light-induced stomatal opening, has been characterized in arabidopsis and grapevine. In this work, we studi...

journal_title：Molecular biology reports

authors： Rodríguez-Hoces de la Guardia A,Ugalde MB,Lobos-Diaz V,Romero-Romero JL,Meyer-Regueiro C,Inostroza-Blancheteau C,Reyes-Diaz M,Aquea F,Arce-Johnson P

更新日期：2021-01-27 00:00:00

abstract：:India has a rich heritage of rearing cattle where farmers selected native cattle suitable to their local agro-ecological conditions for centuries. It is reflected in 50 indigenous breeds of cattle, besides many lesser known populations not explored so far. It is the need of the hour to characterize such populations to...

journal_title：Molecular biology reports

authors： Sharma R,Ahlawat S,Sharma H,Bhagat RL,Singh PK,Tantia MS

更新日期：2020-08-01 00:00:00

abstract：:The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice. The tumor xenograft models were established and randomly assigned to 4 groups: control group, Endostar group (1.5 mg/kg day, once daily for 3 weeks), chemotherap...

journal_title：Molecular biology reports

authors： Chang L,Guo F,Lv Y,Wang Y,Huo B,Wang L,Liu W

更新日期：2013-01-01 00:00:00

abstract：:We examined genetic associations of previously identified sequence variants with bone mineral density and their heterogeneity by gender. Large-scale cohort data were used including a total of 8,419 subjects (4,034 males and 4,385 females) from the Korean Association REsource (KARE) cohort. Bone speed of sound (SOS) va...

journal_title：Molecular biology reports

authors： Woo J,Kim Y,Lee C

更新日期：2012-03-01 00:00:00

abstract：:The interferon-inducible human MxA protein plays an important role in innate defense against an array of viruses. One might expect allelic diversity at the MxA locus to influence the timing and magnitude of its expression or even the range of viruses whose biological cycle is inhibited by the encoded product. Here we ...

journal_title：Molecular biology reports

authors： Duc TT,Farnir F,Michaux C,Desmecht D,Cornet A

更新日期：2012-08-01 00:00:00

abstract：:Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence, this study evaluated the cardioprotective mechanism(s) of Morin against isoproterenol induced myocardial necrosis in rats. Male albino Wistar rats were divided ...

journal_title：Molecular biology reports

authors： Verma VK,Malik S,Narayanan SP,Mutneja E,Sahu AK,Bhatia J,Arya DS

更新日期：2019-02-01 00:00:00

abstract：:Sepsis is one of the major health problems all over the world. Early diagnostic of sepsis is an attractive strategy to decrease the mortality of septic patients. However, an effective biomarker that fulfills all the necessary requirements for the accurate characterization of sepsis is still unavailable until now. In t...

journal_title：Molecular biology reports

authors： Liu J,Li J,Deng X

更新日期：2014-05-01 00:00:00

abstract：:It is widely accepted that protein phosphorylation is a major control event in regulating cell cycle. In the present study, a novel M-phase phosphoprotein 6 (MPP6) was identified from black tiger shrimp Penaeus monodon (designated as PmMPP6) by cDNA library and RACE approaches. The full-length cDNA of PmMPP6 was of 69...

journal_title：Molecular biology reports

authors： Zhou J,Qiu L,Jiang S,Zhou F,Huang J,Yang L,Su T,Zhang D

更新日期：2013-02-01 00:00:00

abstract：:Methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism shows considerable heterogeneity in its distribution in humans worldwide. The current study was conducted to investigate whether this polymorphism exhibited adaptive developmental plasticity in the control of the TT-genotype frequency. We screened 1,818 S...

journal_title：Molecular biology reports

authors： Naushad SM,Krishnaprasad C,Devi AR

更新日期：2014-05-01 00:00:00

abstract：:Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor sup...

journal_title：Molecular biology reports

authors： de Lourdes Perim A,Guembarovski RL,Oda JM,Lopes LF,Ariza CB,Amarante MK,Fungaro MH,de Oliveira KB,Watanabe MA

更新日期：2013-07-01 00:00:00

abstract：:Complexity is one of the hallmarks that applies to C2H2 type zinc finger proteins (ZFPs). Structurally distinct clusters of zinc finger modules define an extremely large superfamily of nucleic acid binding proteins with several hundred, perhaps thousands of different members in vertebrates. Recent discoveries have pro...

journal_title：Molecular biology reports

authors： Pieler T,Bellefroid E

更新日期：1994-07-01 00:00:00

abstract：:Micro-RNAs (miRNAs) play key roles in regulating genes of the immune system. The aim of this study was to examine the expression of miR-1, 21 and 125a in the immune cells taken from the peripheral blood of patients suffering from chronic HBV infection (CHB). This cross-sectional study was performed on 60 CHB patients ...

journal_title：Molecular biology reports

authors： Momeni M,Hassanshahi G,Arababadi MK,Kennedy D

更新日期：2014-07-01 00:00:00

abstract：:Relying on the regulation of transcription factors, plants resist to various abiotic and biotic stresses. NAC (NAM, ATAF1/2, CUC2) are one of the largest families of plant-specific transcription factors and known to play important roles in plant development and response to environmental stresses. A new NAC gene was cl...

journal_title：Molecular biology reports

authors： Wang YX

更新日期：2013-11-01 00:00:00

abstract：:Inhibitor of growth protein 3 (ING3), a new member of ING family, is involved in the regulation of various processes. In this study, a full-length cDNA of ING3 (named as RpING3) was cloned from the gill of Ruditapes philippinarum by rapid amplification of cDNA ends method for the first time. The cDNA obtained was 1442...

journal_title：Molecular biology reports

authors： Hu GW,Yan XW,Qin YJ,Nie HT

更新日期：2014-06-01 00:00:00

abstract：:The aim of this study is to investigate whether ketamine, a noncompetitive N-methyl-D: -aspartate receptor (NMDAR) antagonist, had an influence on learning and memory in developing mice. Fifty Kunming mice aged 21 days were randomly divided into 5 subgroups (n = 10 for each) to receive intraperitoneal injection of equ...

journal_title：Molecular biology reports

authors： Peng S,Zhang Y,Wang H,Ren B,Zhang J

更新日期：2011-10-01 00:00:00

abstract：:Mitochondrial disorders are a frequent cause of neurological disability affecting children and adults. Traditionally, molecular diagnosis of mitochondrial diseases was mostly accomplished by the use of Sanger sequencing and PCR-RFLP. However, there are particular drawbacks associated with the use of these methods. Rec...

journal_title：Molecular biology reports

authors： Kauffman MA,Gonzlez-Morón D,Consalvo D,Westergaard G,Vazquez M,Mancini E,Taratuto AL,Rey R,Kochen S

更新日期：2012-06-01 00:00:00

abstract：:Myocilin (MYOC) gene is expressed in many ocular tissues, including the trabecular meshwork, a specialized eye tissue essential in regulating intraocular pressure. Many mutations in MYOC have been detected in primary open-angle glaucoma (POAG). We investigated whether MYOC mutations contributed to the susceptibility t...

journal_title：Molecular biology reports

authors： Qu X,Zhou X,Zhou K,Xie X,Tian Y

更新日期：2010-01-01 00:00:00

abstract：:Metabolic syndrome is an agglomeration of disorders including obesity, diabetes and cardiovascular diseases and characterized as chronic mild inflammation which elevates the circulatory inflammatory markers. This could be due to mitochondrial dysfunction, oxidative stress and hypoxia as a consequence of high fat diet ...

journal_title：Molecular biology reports

authors： Jha D,Mitra Mazumder P

更新日期：2019-04-01 00:00:00

abstract：:Berberine (BBR), an effective compound of Chinese traditional herbal medicine, has preventive effects on diabetes and its complications. In this study, we investigated the therapeutic effects and underlying molecular mechanisms of BBR in rats with high-fat diet and streptozotocin (STZ)-induced diabetic nephropathy mod...

journal_title：Molecular biology reports

authors： Wang FL,Tang LQ,Yang F,Zhu LN,Cai M,Wei W

更新日期：2013-03-01 00:00:00

abstract：:Molecular abnormalities in the 11p15.5 imprinted gene cluster lead to two different growth diseases: Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS). They are mainly caused by epigenetic alterations in one of the two imprinting 11p15 control regions (ICR1 and ICR2). These CpG-rich regions are diffe...

journal_title：Molecular biology reports

authors： Lukova M,Todorova A,Todorov T,Mitev V

更新日期：2013-01-01 00:00:00

abstract：:The full length cDNA sequence of the Tpt1/TCTP (Tumor protein, Translationally-controlled1) gene was identified from Common Carp (Cyprinus carpio, Cyprinidae), and was designated as CcTpt1 gene. The CDS is 510 bp and encodes a 170-amino acid peptide with a typical Tpt1 signature 2 domain, and is a typical Tpt1 protein...

journal_title：Molecular biology reports

authors： Jiang L,Wang Y,Cheng A,Zhang B,Ma L,Liu Y,Sun X

更新日期：2013-10-13 00:00:00

abstract：:One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which encodes the major t...

journal_title：Molecular biology reports

authors： Seven M,Batar B,Unal S,Yesil G,Yuksel A,Guven M

更新日期：2014-01-01 00:00:00

abstract：:Kidney transplantation to treat end-stage renal disease has evolved rapidly from the first successful transplantations to the current widespread use of grafts from both cadaveric and living donors. But acute rejection is still a strong risk factor for chronic rejection in recipients of renal grafts. To investigate pos...

journal_title：Molecular biology reports

authors： Chen G,Mi J,Xiao MZ,Fu YR

更新日期：2012-05-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:A full-length cDNA encoding common bean (Phaseolus vulgaris L.) sucrose synthase (designated as Pv_BAT93 Sus), which catalyses the synthesis and cleavage of sucrose, was isolated from seeds at 15 days after pollination (DAP) by rapid amplification of cDNA ends (RACE). The full-length cDNA of Pv_BAT93 Sus had a 2,418 b...

journal_title：Molecular biology reports

authors： Abid G,Muhovski Y,Jacquemin JM,Mingeot D,Sassi K,Toussaint A,Baudoin JP

更新日期：2012-02-01 00:00:00

abstract：:Cold stress adversely affects the growth and development of seedling of spring soybean. Revealing responses in seedling to cold stress at proteomic level will help us to breed cold-tolerant spring soybean cultivars. In this study, to understand the responses, a proteomic analysis on the leaves of seedlings of one cold...

journal_title：Molecular biology reports

authors： Tian X,Liu Y,Huang Z,Duan H,Tong J,He X,Gu W,Ma H,Xiao L

更新日期：2015-03-01 00:00:00