Analysis of HLA DQ alpha allele and genotype frequencies in populations from Florida.

Abstract:

:HLA DQ alpha allele and genotype frequencies for Caucasian, African American, Haitian, and Hispanic populations in Florida have been estimated. The Florida laboratories involved in these studies collected donor samples from a variety of sites including clinical laboratories, victim and suspect standards, blood banks, county jail detainees, and laboratory personnel. We have determined that the Caucasian and African American DQ alpha genotype frequencies do not deviate significantly from Hardy-Weinberg expectations and as a result of this heterogeneity analyses, data from the four Florida Caucasian populations may be combined and data from the four Florida African American populations may be combined to form two large HLA DQ alpha genotype frequency databanks. Further, data from the Florida Haitian population may be combined with the Florida African American population. Comparison of the combined Florida Caucasian populations, combined Florida African American populations, the Palm Beach Sheriff's Office (PBSO) Hispanic, and PBSO Haitian population with other databases does not support combination because allele frequency distributions are heterogeneous.

journal_name

J Forensic Sci

authors

Crouse CA,Feuer WJ,Nippes DC,Hutto SC,Barnes KS,Coffman D,Livingston SH,Ginsberg L,Glidewell DE

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

731-42

issue

3

eissn

0022-1198

issn

1556-4029

journal_volume

39

pub_type

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