The response of the Intoxilyzer 5000 to five potential interfering substances.

Abstract:

:A study was conducted of potential vapor phase interferents which could be present on human breath and also be capable of inducing a false-positive response for ethanol on the evidential infrared-based breath testing device, the Intoxilyzer-5000. This involved preparation and validation of a range of vapor standards, which were introduced to the instrument using a dynamic flow double-bubbler system. Potential interferents were chosen on the basis of both their infrared signatures and their general availability, and included toluene, m-xylene, o-xylene, methanol and isopropanol. All compounds tested were found to be capable of inducing false-positive readings for ethanol in a highly reproducible manner, as a result of which it has been possible to derive precise least-squares equations describing the ethanol readout expected for any given blood concentration of toluene, m-xylene, o-xylene, methanol and isopropanol. The likelihood of an interference compromising the integrity of the analysis is related to both the toxicological significance and prevalence of a given blood concentration of each solvent, and the point at which the instrumental interference light is triggered in each case.

journal_name

J Forensic Sci

authors

Caldwell JP,Kim ND

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

1080-7

issue

6

eissn

0022-1198

issn

1556-4029

journal_volume

42

pub_type

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