Abstract：
:An elevated serum tryptase concentration is considered a specific marker for systemic mast cell activation, a central feature of anaphylaxis. However, in some cases of acute cardiovascular death, high concentrations of serum tryptase are also observed. We compared the postmortem serum tryptase concentrations in 74 cases assigned to the following four groups: anaphylactic deaths (Group A, n = 20), acute cardiac deaths (Group ACD, n = 30), acute dissecting aneurysm ruptures (Group ADA, n = 10), and controls (Group C, n = 14). Additionally, the cutoff between Group A and the other groups was calculated using receiver-operating characteristic (ROC) curve analysis. Tryptase concentrations were markedly elevated in Group A (p < 0.001), Group ACD (p = 0.015), and Group ADA (p = 0.005). The optimal cutoff was 43 ng/mL, the sensitivity was 90%, and the specificity was 98%. While elevated concentrations of tryptase were noted in practical autopsy cases, due attention should be paid to the differential diagnosis between anaphylactic and acute cardiovascular deaths.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Xiao N,Li DR,Wang Q,Zhang F,Yu YG,Wang HJdoi
10.1111/1556-4029.13420subject
Has Abstractpub_date
2017-09-01 00:00:00pages
1336-1338issue
5eissn
0022-1198issn
1556-4029journal_volume
62pub_type
杂志文章abstract：:Nosocomial infections have become a major issue of public health and lead to an increasing number of suits for damages. We present a rare case of Aspergillus contamination during cardiac surgery, describe the medicolegal investigation, and present the new system for compensation of bodily injury after nosocomial infec...
journal_title：Journal of forensic sciences
pub_type：
doi：10.1111/1556-4029.13328
更新日期：2017-05-01 00:00:00
abstract：:Previously reported cases of suicide by intravenous barbiturates, as well as two other unusual cases [5,6], are compared in Table 2. All decedents were either medical or paramedical personnel and familiar with the drugs and the routes of administration used for their suicides. Lethal is used in veterinary euthanasia a...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1979-10-01 00:00:00
abstract：:Using an enzyme-linked immunosorbent assay (ELISA), this study investigated the use of monoclonal antibodies for detecting secreted ABH blood group substances in semen and saliva. The results demonstrated that the behavior of some monoclonals were unpredictable and often failed to detect the corresponding antigen in a...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:A simple, rapid radioimmunoassay employing 125-I-labeled secobarbital derivative has been developed and has been shown to be capable of detecting at the nanogram level a variety of barbiturates in urine as well as in plasma. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Human fetal skeletal elements of different gestational ages were screened with multiple mesh sizes (6.4 mm [1/4 inch], 3.2 mm [1/8 inch], 2.0 mm, and 1.0 mm) to determine their recovery rates. All remains were previously macerated, and no significantly damaged elements were used. The 6.4 mm mesh allowed a large loss o...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12922
更新日期：2016-01-01 00:00:00
abstract：:A case of apparent suicide by injection of snake venom was investigated. Evidence found at the scene and presumably used for self-injection was positive for nonspecific venom but had the characteristics of a viper venom. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：:Opium is the raw material for the production of heroin, and the characterization of opium seizures through laboratory analysis is a valuable tool for law enforcement agencies to trace clandestine opium production and trafficking. In this work, a method for opium profiling based on the relative content of five principa...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13190
更新日期：2016-11-01 00:00:00
abstract：:The analysis of cocaine base is a major part of the forensic drug chemist's workload. Simplifying quantitative methodology can assist the drug chemist. Methods currently employed for quantitation of cocaine base utilize either an internal standard or a direct comparison. This gas chromatographic method for the quantit...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Internal standards are commonly used for the quantitative determination of drugs of abuse and their metabolites (drug/metabolite) in biological fluids and tissues by the selective ion monitoring (SIM) gas chromatography/mass spectrometry (GC/MS) procedure. Analogs of drugs/metabolites that are labeled with three or mo...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：:The duty to protect, or Tarasoff duty, has been conceptualized as arising solely in the context of a clinical setting. A recent California Supreme Court ruling in People v. Clark adds legal, clinical, and ethical dilemmas to the oftentimes contentious Tarasoff issue. Though the Tarasoff issue is but a minor legal poin...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:This work compares epidemiological and sociological data on persons having committed suicide in 2002 and in 2012 through a retrospective study of every suicide case having led to an autopsy at the Institute for Forensic Medicine of Lyon in 2002 and in 2012. The study included sociodemographic data, medical data, and t...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12888
更新日期：2016-01-01 00:00:00
abstract：:Currently in the United States there is little direction for what constitutes sufficient guidelines for DNA mixture interpretation. While a standardized approach is not possible or desirable, more definition is necessary to ensure reliable interpretation of results is carried out. In addition, qualified DNA examiners ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01046.x
更新日期：2009-07-01 00:00:00
abstract：:Adermatoglyphia is a very rare autosomal-dominant condition that is genetically inherited and causes an individual to be born without conventional ridge detail on either their palmar or plantar surfaces (the fingers and palms of the hands and the toes and the soles of the feet). While adermatoglyphia has been the focu...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.14597
更新日期：2021-01-01 00:00:00
abstract：:Reproducibility of quantitative PCR results is dependent on the generation of consistent calibration curves via accurate volume transfers and instrument performance. A review of 14 standard curves, using two different QuantDuo® standard DNA lots, showed variability of cycle threshold values between assays were larger ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01460.x
更新日期：2010-09-01 00:00:00
abstract：:A 38-year-old nondiabetic female developed fatal hypoglycemia when chlorpropamide (Diabinese) was accidentally substituted for acetaminophen (Tylenol) with codeine no. 3 in a pharmacy dispensing error. When found, the patient's serum glucose was less than 20 mg/dL. The serum chlorpropamide level on hospital admission ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Previous studies have indicated that the relative position of the inferior alveolar canal and its mental and mandibular foramina in adults vary with age and show sexual dimorphism. Conceivably, these purported differences could be of forensic value for determining identity of human remains. This study was designed to ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01508.x
更新日期：2011-01-01 00:00:00
abstract：:We present an unusual example of multiple mesosternal foramina (MMF). The alignment of the paired defects is unlike any previously described. Although single sternal defects are often encountered, paired defects are quite uncommon. This is the first documented example of bilateral paired defects in the sternum. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Phencyclidine (PCP) can be detected in human hair wih commercially available radioimmunoassay regents. hair samples of all subjects admitting PCP use were positive, while thin-layer chromatographic urine analyses were positive in only one of seven cases. Presumably the drug is incorporated into the hair during period...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:The demographic and toxicological characteristics of deliberate (SUI, n = 50) and accidental (ACC, n = 927) fatal heroin overdose cases were examined. SUI cases were more likely to be female, had lower body mass indices, were more likely to be enrolled in treatment and less likely to have hepatic pathology. The median...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01385.x
更新日期：2010-07-01 00:00:00
abstract：:Preventative dental treatment has reduced caries incidence and thereby rendered dental identification, in caries-free individuals, more difficult. An alternate method comparing spatial relationships of dental structures in digitized superimposed antemortem and postmortem radiographs has been previously developed. This...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The aim of this study was to assess the histomorphological features of the fourth rib and to develop age-predicting equations for Koreans. Sixty-four rib samples (36 males and 28 females) obtained from forensic cases were used for developing equations. Two thin sections (<100-microm thick) per sample were prepared by ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2007.00566.x
更新日期：2007-11-01 00:00:00
abstract：:To estimate postmortem interval (PMI), spontaneous cleavage of the third component of complement (C3) was studied in aged blood and cadaveric blood by crossed immunoelectrophoresis. Using the kinetics of C3 cleavage in vitro described as dC/dt = -kC, where C is the concentration of native C3 at time t and k is a first...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:A sensitive analysis of sulfide in blood was established, using an extractive alkylation technique. Pentafluorobenzyl bromide was used as the alkylating agent, tetradecyldimethylbenzylammonium chloride as the phase-transfer catalyst, and potassium dihydrogenphosphate as the buffer to suppress the formation of sulfide....
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Pica is characterized by the persistent eating of non-nutritive substances over some time that is inappropriate for the maturation stage of the individual and is not culturally sanctioned. A 9-year-old boy with Goldenhar syndrome, significant developmental delay and pica, collapsed and died after a short history of di...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12520
更新日期：2014-09-01 00:00:00
abstract：:The likelihood of dipteran maggots colonizing a corpse due to nocturnal oviposition can be used to challenge the postmortem interval (PMI) estimated assuming diurnal oviposition. Earlier experiments tested nocturnal oviposition behavior by exposing fresh baits once during a single night. In this pilot study, ovipositi...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01095.x
更新日期：2009-09-01 00:00:00
abstract：:Data from 100 cases of alleged rape victims demonstrate why the author believes the AP test to be a reliable tool, when employed by an expert for the identification of seminal fluid. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1978-10-01 00:00:00
abstract：:The objective of this study was to compare the accuracy of contact and laser 3D scanners in tooth mark analysis. Ten dental casts were scanned with both 3D scanners. Seven linear measurements were made from the 3D images of dental casts and biting edges generated with DentalPrint© software (University of Granada, Gran...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12598
更新日期：2015-01-01 00:00:00
abstract：:The separation of 12 explosives by capillary electrophoresis was optimized with the aid of artificial neural networks (ANNs). The selectivity of the separation was manipulated by varying the concentration of sodium dodecyl sulfate (SDS) and the pH of the electrolyte, while maintaining the buffer concentration at 10 mM...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The estimation of postmortem interval (PMI) based on successional patterns of adult insects is largely limited, due to the lack of potential PMI markers. Sex and size of adult insects could be easily used for such estimation. In this study, sex- and size-related patterns of carrion attendance by adult insects were ana...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13376
更新日期：2017-09-01 00:00:00
abstract：:Four individuals died as the result of a propane explosion. As with many propane explosions, the question was raised as to the adequacy of the product's odorization after the autopsy studies had been conducted. In most cases, this question leads to litigation. Ethyl mercaptan is a widely used odorant for propane and w...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
