An evaluation of the balanced placebo design in alcohol administration research.

Abstract:

:Results from a study using the balanced placebo design to assess alcohol's effects on anxiety raise serious doubts about the utility of the design even at moderate blood alcohol concentrations. Despite being informed that they were not drinking alcohol, 44% of the subjects who were administered alcohol reported consuming at least some alcohol. Moreover, subjects' scores on the Marlowe-Crowne Social Desirability Index (MCSD) were associated with deception success, suggesting that individual differences in reporting bias influence the manipulation. In contrast, only 6% of subjects who were told that they had consumed alcohol but were given tonic water were not deceived. Among subjects in this placebo condition, scores on the MCSD were not associated with success of the deception. These data suggest that at a moderate dose of alcohol, drink deception in the antiplacebo condition is much more difficult to execute than in the placebo condition, and that deception in the former condition may be confounded with experimenter demand.

journal_name

Addict Behav

journal_title

Addictive behaviors

authors

Sayette MA,Breslin FC,Wilson GT,Rosenblum GD

doi

10.1016/0306-4603(94)90034-5

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

333-42

issue

3

eissn

0306-4603

issn

1873-6327

pii

0306-4603(94)90034-5

journal_volume

19

pub_type

临床试验,杂志文章,随机对照试验
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