Correlation of transcranial Doppler ultrasonography with MRI and MRA in the evaluation of sickle cell disease patients with prior stroke.

Abstract:

:We prospectively evaluated a group of patients with sickle cell disease and a clinical history of prior stroke, comparing transcranial Doppler sonography (TCD) to both magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) to determine its efficacy for the detection of flow abnormalities associated with prior cerebral infarction. Using MRI as the standard examination, there was 94% sensitivity and 30% specificity, and using MRA as the standard examination, there was 91% sensitivity and 22% specificity. We concur with other reports that the transcranial Doppler examination is a highly sensitive study. In our group of sickle cell disease patients with prior stroke, TCD reliably detected flow abnormalities that correlated to areas of prior cerebral infarction.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Kogutt MS,Goldwag SS,Gupta KL,Kaneko K,Humbert JR

doi

10.1007/BF02012192

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

204-6

issue

3

eissn

0301-0449

issn

1432-1998

journal_volume

24

pub_type

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