Effect of phenazone (antipyrine) on the prostanoid formation in human umbilical arteries perfused in vitro.

Abstract:

:The influence of phenazone on the production of prostacyclin and thromboxane in human umbilical arteries was investigated by in vitro perfusion. With perfusate concentrations ranging from 10(-7) to 10(-4) M a decrease in the formation of both prostanoids was observed. The inhibitory effect of phenazone on prostanoid formation was found to be equal to that of indomethacin.

journal_name

Gynecol Obstet Invest

authors

Haugen G,Stray-Pedersen S,Bjøro K

doi

10.1159/000292366

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

8-10

issue

1

eissn

0378-7346

issn

1423-002X

journal_volume

39

pub_type

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