M-band structure, M-bridge interactions and contraction speed in vertebrate cardiac muscles.

abstract：:Extensor digitorum longus muscles of normal mice (C57BL/10ScSn hereafter called C57) were orthotopically transplanted into dystrophin-deficient mice (mdx) and reciprocally, mdx Extensor digitorum longus muscles were transplanted into C57 mice. After an initial phase of degeneration, transplanted muscles regenerate nea...

journal_title：Journal of muscle research and cell motility

authors： Moens PD,Van-Schoor MC,Maréchal G

更新日期：1996-02-01 00:00:00

abstract：:We found that the active tension of C2C12 myotubes that had been subjected to artificial exercise for ~10 days decreased rapidly after termination of the artificial exercise. When differentiated C2C12 myotubes were subjected to continuous 1 Hz artificial exercise for ~10 days, the active tension increased to ~4× compa...

journal_title：Journal of muscle research and cell motility

authors： Fujita H,Hirano M,Shimizu K,Nagamori E

更新日期：2010-12-01 00:00:00

abstract：:The mechanical events following release of ATP from P3-1-(2-nitro)phenylethyladenosine-5'-triphosphate (caged-ATP) in skinned guinea pig taenia coli smooth muscle in rigor were investigated. A rigor force of about 25-35% of the maximal active force was obtained by removing ATP at the plateau of a maximal active contra...

journal_title：Journal of muscle research and cell motility

authors： Arner A,Goody RS,Rapp G,Rüegg JC

更新日期：1987-10-01 00:00:00

abstract：:The hypothesis that calmodulin (CaM) may act as a positive modulator of junctional SR Ca2+-release channel/ ryanodine receptor (RyRl) rests largerly on the demonstrated capacity of CaM to interact structurally and functionally with RyRl at pCa > 8 (Tripathy et al., 1995). The goal of the present [3H]-ryanodine binding...

journal_title：Journal of muscle research and cell motility

authors： Damiani E,Margreth A

更新日期：2000-01-01 00:00:00

abstract：:ADF/cofilins disassemble the actin filament and contribute to a wide range of actin dynamics. These proteins are regulated by several factors, including phosphorylation, pH and mechanical forces. Although the cofilin-decorated actin filament structure was published recently, the mechanisms of these regulating factors ...

journal_title：Journal of muscle research and cell motility

authors： Narita A

更新日期：2020-03-01 00:00:00

abstract：:We determined the effects of epigallocatechin-3-gallate (EGCG) and epicatechin (EC), on pump turnover and Ca2+ transport by the cardiac form of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA). Fluorescence spectroscopy was used to directly measure SERCA ATPase activity and to measure Ca2+ uptake into cardia...

journal_title：Journal of muscle research and cell motility

authors： Kargacin ME,Emmett TL,Kargacin GJ

更新日期：2011-09-01 00:00:00

abstract：:The aim of the present study was to examine the temperature dependence of active force in lengthening and shortening muscle. Experiments were done, in vitro, on bundles of intact fibres (fibre length L(0) ~2 mm; sarcomere length ~2.5 μm) isolated from a rat fast muscle (flexor hallucis brevis) and a ramp length change...

journal_title：Journal of muscle research and cell motility

authors： Roots H,Pinniger GJ,Offer GW,Ranatunga KW

更新日期：2012-10-01 00:00:00

abstract：:Effects of Mn2+ and Ca2+ on the mechanical properties of glycerinated myofibrillar bundles originating from slow S1 type muscle fibres of superficial flexor muscles of the lobster Nephrops norvegicus were investigated. Mn2+ (5-20 microM) activated the preparations in a dose-dependent manner. The sensitivity of myofibr...

journal_title：Journal of muscle research and cell motility

authors： Holmes JM,Hilber K,Galler S,Neil DM

更新日期：1998-06-01 00:00:00

abstract：:MagFluo-4 fluorescence (Ca2+) transients associated with action potentials were measured in intact muscle fibres, manually dissected from toads ( Leptodactylus insularis ) or enzymatically dissociated from mice. In toads, the decay phase of the Ca2+ transients is described by a single exponential with a time constant ...

journal_title：Journal of muscle research and cell motility

authors： Caputo C,Bolaños P,Gonzalez A

更新日期：2004-01-01 00:00:00

abstract：:The ability for muscle to repeatedly generate force is limited by fatigue. The cellular mechanisms behind muscle fatigue are complex and potentially include breakdown at many points along the excitation-contraction pathway. In this paper we construct a mathematical model of the skeletal muscle excitation-contraction p...

journal_title：Journal of muscle research and cell motility

authors： Shorten PR,O'Callaghan P,Davidson JB,Soboleva TK

更新日期：2007-01-01 00:00:00

abstract：:Single muscle fiber sodium dodecyl sulfate polyacrylamide gel-electrophoresis (SDS-PAGE) is a sensitive technique for determining skeletal muscle myosin heavy chain (MHC) composition of human biopsy samples. However, the number of fibers suitable to represent fiber type distribution via this method is undefined. Muscl...

journal_title：Journal of muscle research and cell motility

authors： Murach KA,Bagley JR,McLeland KA,Arevalo JA,Ciccone AB,Malyszek KK,Wen Y,Galpin AJ

更新日期：2016-04-01 00:00:00

abstract：:Although a substantial literature exists on the in vitro polymerization of purified myosin, little is known about native thick filament assembly, remodeling or turnover. We have recently described a cell-free system (Bouche et al., 1988) to examine the interactions between thick filaments and soluble, newly synthesize...

journal_title：Journal of muscle research and cell motility

authors： Goldfine SM,Einheber S,Fischman DA

更新日期：1991-04-01 00:00:00

abstract：:Myosin has been purified from chicken pectoralis muscle at various stages of development, from 10 days' incubation to approximately 10 months after hatching. Embryonic myosin from the earliest stage showed a high level of ATPase activity, similar to that obtained for adult pectoralis myosin. Two-dimensional peptide ma...

journal_title：Journal of muscle research and cell motility

authors： Lowey S,Benfield PA,LeBlanc DD,Waller GS

更新日期：1983-12-01 00:00:00

abstract：:2,3-butanedione 2-monoxime (BDM, 3-30 mM) decreased twitch force of intact ventricular trabeculae isolated from 19-day embryonic chick hearts in a dose-dependent manner. The responses to BDM were rapid and reversible. In an attempt to determine the cellular basis for the inhibitory effect of BDM, experiments were carr...

journal_title：Journal of muscle research and cell motility

authors： Brotto MA,Fogaça RT,Creazzo TL,Godt RE,Nosek TM

更新日期：1995-02-01 00:00:00

abstract：:The effects of two amino acids, arginine which has a positively charged side-chain and glutamate which has a negatively charged side-chain on the Ca2+-activation properties of the contractile apparatus were examined in four structurally and functionally different types of skeletal muscle; long- and short-sarcomere fib...

journal_title：Journal of muscle research and cell motility

authors： Jame DW,West JM,Dooley PC,Stephenson DG

更新日期：2004-01-01 00:00:00

abstract：:The in vivo state of assembly of myosin in vertebrate smooth muscle is controversial. In vitro studies on purified smooth muscle myosin show that it is monomeric (10S) under relaxing conditions and filamentous under contraction conditions. Electron microscopic and antibody labelling studies of intact smooth muscles, o...

journal_title：Journal of muscle research and cell motility

authors： Xu JQ,Gillis JM,Craig R

更新日期：1997-06-01 00:00:00

abstract：:A high resolution, time efficient method is described for determining the complex modulus of activated striated muscle. In this method the applied oscillation of muscle length takes the form of pseudo-random binary noise, PRBN. As a time-domain signal, PRBN is an extension of the double step approach to include n step...

journal_title：Journal of muscle research and cell motility

authors： Rossmanith GH

更新日期：1986-08-01 00:00:00

abstract：:Telokin, a 17 kDa smooth muscle specific protein, consists of the C-terminal domain of MLCK, is phosphorylated by PKA and PKG at Ser13 in vivo (Wu et al. (1998) J Biol Chem 273: 11362-11369; Walker et al. (2001) J. Biol Chem 276: 24519-24524) and is proposed to induce Ca2+-desensitization through activation of myosin ...

journal_title：Journal of muscle research and cell motility

authors： Choudhury N,Khromov AS,Somlyo AP,Somlyo AV

更新日期：2004-01-01 00:00:00

abstract：:Dr. John Gergely passed away on July 26, 2013 after a long and distinguished career. His publications spanned 67 years. He founded the Department of Muscle Research in the Retina Foundation (which later became the Boston Biomedical Research Institute) and served as director for 34 years. Dr. Gergely served on the edit...

journal_title：Journal of muscle research and cell motility

authors： Greaser ML,Potter JD,Thomas DD,Strasburg GM,Lehrer SS,Wang CL,Grabarek Z

更新日期：2013-12-01 00:00:00

abstract：:The kinetics of smooth muscle are thought to be partially determined by the level of the expression of the 7 amino acid insert, SMB, in the myosin heavy chain, as SMB is generally expressed at higher levels in faster smooth muscle. In this study, we determined the role of this insert on shortening velocity and force r...

journal_title：Journal of muscle research and cell motility

authors： Karagiannis P,Babu GJ,Periasamy M,Brozovich FV

更新日期：2004-01-01 00:00:00

abstract：:The characteristics of the titin filament in the vicinity of the Z-line were investigated using immunoelectron microscopy. We used monoclonal titin antibodies T-11 and T-12 on single fibres of frog skeletal muscle, and on Z-line-extracted fibres. It is well established that the I-band region of titin is elastic. We fi...

journal_title：Journal of muscle research and cell motility

authors： Trombitás K,Pollack GH

更新日期：1993-08-01 00:00:00

abstract：:The effect of Ca2+ activation on the apparent rate constant governing the dissociation of force generating myosin crossbridges was studied in skinned rabbit adductor magnus fibres (fast-twitch) at 21 +/- 1 degree C. Simultaneous measurements of Ca2(+)-activated isometric force and ATPase activity were conducted in par...

journal_title：Journal of muscle research and cell motility

authors： Kerrick WG,Potter JD,Hoar PE

更新日期：1991-02-01 00:00:00

abstract：:Using a variety of techniques, we have demonstrated the presence of at least two fibre types in Limulus median telson levator muscle. By light and electron microscopy, large (2,156 microns 2 mean cross-sectional area) fibres have A-bands of 4.1 microns, one-half I bands of 2.15 microns and Z lines less than or equal t...

journal_title：Journal of muscle research and cell motility

authors： Levine RJ,Davidheiser S,Kelly AM,Kensler RW,Leferovich J,Davies RE

更新日期：1989-02-01 00:00:00

abstract：:The β-adrenergic receptor stimulation improves endurance in fast twitch muscles and these effects are sensitive to extracellular Ca2+ influx. Present study is aimed to determine the effects of adrenaline, with different concentrations of extracellular Ca2+[Formula: see text], on the contractility and endurance of slow...

journal_title：Journal of muscle research and cell motility

authors： Rizvi MH,Abdul Azeem M,Savanur A

更新日期：2019-12-01 00:00:00

abstract：:The distribution of Ca2+ and Mg2+ among the 'regulatory' cation binding sites of troponin (T-sites) and the strong, Ca2+-Mg2+ binding sites of troponin and parvalbumins (P-sites) in the sarcoplasm of a muscle was calculated. At rest, 60% of the T-sites were metal free, while 92% of the P-sites were loaded with Mg2+. I...

journal_title：Journal of muscle research and cell motility

authors： Gillis JM,Thomason D,Lefèvre J,Kretsinger RH

更新日期：1982-12-01 00:00:00

abstract：:White muscle fibres from dogfish were used to compare the energetic costs of shortening by fully active muscle and by relaxing muscle. The muscle preparation was tetanized for 0.6 s and shortened either during stimulation or during relaxation. The distance shortened was 1 mm (about 15% L0, the muscle length optimum fo...

journal_title：Journal of muscle research and cell motility

authors： Lou F,Curtin NA,Woledge RC

更新日期：1998-10-01 00:00:00

abstract：:The myosin light chains of slow muscles from different species have been examined two-dimensional gel electrophoresis. While the myosin light chain 2S of mammalian soleus muscles (rabbit, rat and guinea-pig) could not be distinguished from that of avian anterior latissimus dorsi (chicken and turkey), the 1S light chai...

journal_title：Journal of muscle research and cell motility

authors： Carraro U,dalla Libera L,Catani C

更新日期：1981-09-01 00:00:00

abstract：:Appropriate organization of cytoskeletal components are required for normal distribution and intracellular localization of different ion channels and proteins involved in calcium homeostasis, signal transduction, and contractile function of striated muscle. Proteins of the contractile system are in direct or indirect ...

journal_title：Journal of muscle research and cell motility

authors： Gönczi M,Dienes B,Dobrosi N,Fodor J,Balogh N,Oláh T,Csernoch L

更新日期：2020-01-18 00:00:00

abstract：:Monoclonal antibodies (mAb's) have been raised against proteins in preparations of Z-discs isolated from honeybee fibrillar flight muscle. These antibodies have identified four Z-disc antigens on immunoblots of honeybee fibrillar proteins. Antibody alpha binds to the 90-100 kD protein, alpha-actinin; mAb P interacts w...

journal_title：Journal of muscle research and cell motility

authors： Saide JD,Chin-Bow S,Hogan-Sheldon J,Busquets-Turner L

更新日期：1990-04-01 00:00:00

abstract：:CapZ is a widely distributed and highly conserved, heterodimeric protein, that nucleates actin polymerization and binds to the barbed ends of actin filaments, preventing the addition or loss of actin monomers. CapZ interaction with actin filaments was shown to be of high affinity and decreased in the presence of PIP2....

journal_title：Journal of muscle research and cell motility

authors： Papa I,Astier C,Kwiatek O,Raynaud F,Bonnal C,Lebart MC,Roustan C,Benyamin Y

更新日期：1999-02-01 00:00:00