Epigallocatechin-3-gallate has dual, independent effects on the cardiac sarcoplasmic reticulum/endoplasmic reticulum Ca2+ ATPase.

abstract：:Small but statistically significant shifts (hysteresis) between the up (increasing tension direction) and down (decreasing tension) pCa/tension relation for several muscle types of the rabbit and rat were found. The largest shift is, at most, 0.093 p units or 60% of that reported for the barnacle muscle. The direction...

journal_title：Journal of muscle research and cell motility

authors： Brandt PW,Gluck B,Mini M,Cerri C

更新日期：1985-04-01 00:00:00

abstract：:Stretchin-klp is a newly described protein in Drosophila indirect flight muscles (IFM) that migrates on SDS gels as two distinct components of approximately 225 and 231 kD. Although the larger isoform is IFM specific, the smaller stretchin-klp isoform is expressed not only in IFM, but also in wild-type tissues of the ...

journal_title：Journal of muscle research and cell motility

authors： Patel SR,Saide JD

更新日期：2005-01-01 00:00:00

abstract：:Mechanical properties of myofibrillar bundles from single chemically skinned fibres from the superficial abdominal flexor muscle of the Norway lobster Nephrops norvegicus were measured, and the protein content of these fibres was analysed by SDS-PAGE. Two slow fibre phenotypes (S1, S2) were distinguished on the basis ...

journal_title：Journal of muscle research and cell motility

authors： Holmes JM,Hilber K,Galler S,Neil DM

更新日期：1999-04-01 00:00:00

abstract：:The sonic muscle of the oyster toadfish, Opsanus tau, can produce unfused contractions at 300 Hz. Electron microscopy shows a great abundance of the Sarcoplasmic reticulum (SR) in this muscle, but no functional characterization of the capabilities of the SR has been reported. We measured the oxalate-supported Ca2+ upt...

journal_title：Journal of muscle research and cell motility

authors： Feher JJ,Waybright TD,Fine ML

更新日期：1998-08-01 00:00:00

abstract：:A set of five differential equations has been found which gives a satisfactory account of the isotonic and isometric properties of striated muscle. Four of these differential equations give an equally satisfactory account of the results of length-drive experiments with sinusoidal variation of length. In this case, the...

journal_title：Journal of muscle research and cell motility

authors： Cheung AS,Gray BF

更新日期：1984-10-01 00:00:00

abstract：:The developmental shift in contractile protein isoform expression in the rodent heart likely affects actin-myosin cross-bridge interactions. We compared the Ca2+ sensitivity for force generation and cross-bridge cycling kinetics in neonatal (postnatal days 0-3) and adult (day 84) rats. The force-pCa relationship was d...

journal_title：Journal of muscle research and cell motility

authors： Prakash YS,Cody MJ,Housmans PR,Hannon JD,Sieck GC

更新日期：1999-10-01 00:00:00

abstract：:The pattern of spontaneous skeletal muscle degeneration and clinical recovery hindlimb muscles of the mdx mutant mouse was examined for functional and metabolic confirmation of apparent structural regeneration. The contractile properties, histochemical staining and myosin light chain and parvalbumin contents of extens...

journal_title：Journal of muscle research and cell motility

authors： Anderson JE,Bressler BH,Ovalle WK

更新日期：1988-12-01 00:00:00

abstract：:RNA-binding motif protein 3 (RBM3), a stress-inducible RNA-binding protein that increases protein synthesis and confers cell protection in multiple cell types, has been identified as a possible regulator of skeletal muscle mass. Therefore, the primary aim of this study was to examine the impact of elevated RBM3 on ske...

journal_title：Journal of muscle research and cell motility

authors： Van Pelt DW,Confides AL,Judge AR,Vanderklish PW,Dupont-Versteegden EE

更新日期：2018-04-01 00:00:00

abstract：:Several mutations in the beta-myosin heavy chain gene cause hypertrophic cardiomyopathy. This study investigates (1) the in vitro velocities of translocation of fluorescently-labelled actin by beta-myosin purified from soleus muscle of 30 hypertrophic cardiomyopathy patients with seven distinct beta-myosin heavy chain...

journal_title：Journal of muscle research and cell motility

authors： Cuda G,Fananapazir L,Epstein ND,Sellers JR

更新日期：1997-06-01 00:00:00

abstract：:The effects of a ramp stretch (amplitude <6% muscle fibre length (L0), speed < 13L0 s(-1)) on twitch tension and twitch tension re-development were examined in intact mammalian (rat) fast and slow muscle fibre bundles. The experiments were done in vitro at 20 degrees C and at an initial sarcomere length of 2.68 microm...

journal_title：Journal of muscle research and cell motility

authors： Mutungi G,Ranatunga KW

更新日期：2001-01-01 00:00:00

abstract：:Although a substantial literature exists on the in vitro polymerization of purified myosin, little is known about native thick filament assembly, remodeling or turnover. We have recently described a cell-free system (Bouche et al., 1988) to examine the interactions between thick filaments and soluble, newly synthesize...

journal_title：Journal of muscle research and cell motility

authors： Goldfine SM,Einheber S,Fischman DA

更新日期：1991-04-01 00:00:00

abstract：:Filamin binds to F-actin and influences the myosin-actin interaction. At relatively low concentrations, filamin activates actomyosin Mg2+-ATPase, whereas higher concentrations of filamin exert an inhibitory effect. Activation of ATPase activity occurs under conditions where a loose meshwork of actin filaments is prese...

journal_title：Journal of muscle research and cell motility

authors： Dabrowska R,Goch A,Osińska H,Szpacenko A,Sosinski J

更新日期：1985-02-01 00:00:00

abstract：:Isolated fibres from various muscles were skinned mechanically in oil. From a Ca2+-loaded micropipette, local applications of Ca2+ were made. These produced a limited contraction which relaxed spontaneously. The time-course of sarcomere shortening and re-lengthening was recorded by microcinephotography. Application of...

journal_title：Journal of muscle research and cell motility

authors： Gillis JM

更新日期：1997-08-01 00:00:00

abstract：:The sarcomere of striated muscle is a very efficient machine transforming chemical energy into movement. However, a wrong distribution of the generated forces may lead to self-destruction of the engine itself. A well-known example for this is eccentric contraction (elongation of the sarcomere in the activated state), ...

journal_title：Journal of muscle research and cell motility

authors： Agarkova I,Ehler E,Lange S,Schoenauer R,Perriard JC

更新日期：2003-01-01 00:00:00

abstract：:Skeletal muscle has a remarkable ability to respond to different physical stresses. Loading muscle through exercise, either anaerobic or aerobic, can lead to increases in muscle size and function while, conversely, the absence of muscle loading stimulates rapid decreases in size and function. A principal mediator of t...

journal_title：Journal of muscle research and cell motility

authors： Graham ZA,Gallagher PM,Cardozo CP

更新日期：2015-10-01 00:00:00

abstract：:The term 'microtubule dynamics' is often used to describe assembly/disassembly characteristics of this important cytoskeletal polymer. The ability to image microtubules in live Dictyostelium cells has revealed additional dynamic components, acting on the individual assembled tubules. At least two separate forces are i...

journal_title：Journal of muscle research and cell motility

authors： Koonce MP,Khodjakov A

更新日期：2002-01-01 00:00:00

abstract：:Myosin binding protein C (MYBPC) is a crucial component of the sarcomere and an important regulator of muscle function. While mutations in different myosin binding protein C (MYBPC) genes are well known causes of various human diseases, such as hypertrophic (HCM) and dilated (DCM) forms of cardiomyopathy as well as sk...

journal_title：Journal of muscle research and cell motility

authors： Knöll R

更新日期：2012-05-01 00:00:00

abstract：:Tropomyosins (Tm) in humans are expressed from four distinct genes and by alternate splicing >40 different Tm polypeptide chains can be made. The functional Tm unit is a dimer of two parallel polypeptide chains and these can be assembled from identical (homodimer) or different (heterodimer) polypeptide chains provided...

journal_title：Journal of muscle research and cell motility

authors： Janco M,Suphamungmee W,Li X,Lehman W,Lehrer SS,Geeves MA

更新日期：2013-08-01 00:00:00

abstract：:2,3-butanedione 2-monoxime (BDM, 3-30 mM) decreased twitch force of intact ventricular trabeculae isolated from 19-day embryonic chick hearts in a dose-dependent manner. The responses to BDM were rapid and reversible. In an attempt to determine the cellular basis for the inhibitory effect of BDM, experiments were carr...

journal_title：Journal of muscle research and cell motility

authors： Brotto MA,Fogaça RT,Creazzo TL,Godt RE,Nosek TM

更新日期：1995-02-01 00:00:00

abstract：:Muscle development involves a complex sequence of time and spatially regulated cellular events leading to the formation of highly specialised syncytial muscle cells displaying a common feature, the capacity of contraction. Analyses of mechanisms controlling muscle development reveals that the main steps of muscle form...

journal_title：Journal of muscle research and cell motility

authors： Maqbool T,Jagla K

更新日期：2007-01-01 00:00:00

abstract：:Rotary-shadowed filamin molecules appear as long, highly flexible rods curved into a variety of configurations. The particles observed were 2.7 nm wide but had contour lengths of either 98 nm or 193 nm. The longer particles are probably end-to-end dimers of the shorter but it is not clear how many polypeptide chains t...

journal_title：Journal of muscle research and cell motility

authors： Castellani L,Offer G,Elliott A,O'Brien EJ

更新日期：1981-06-01 00:00:00

abstract：:The β-adrenergic receptor stimulation improves endurance in fast twitch muscles and these effects are sensitive to extracellular Ca2+ influx. Present study is aimed to determine the effects of adrenaline, with different concentrations of extracellular Ca2+[Formula: see text], on the contractility and endurance of slow...

journal_title：Journal of muscle research and cell motility

authors： Rizvi MH,Abdul Azeem M,Savanur A

更新日期：2019-12-01 00:00:00

abstract：:Recent studies have revealed unconventional myosin V to be an important actin-based molecular motor involved in vesicular movement. In this paper we report the molecular characterization of the Drosophila myosin V, identified by reverse genetics. The gene encodes a 1792-residue, 207 kDa heavy chain polypeptide which p...

journal_title：Journal of muscle research and cell motility

authors： Bonafé N,Sellers JR

更新日期：1998-02-01 00:00:00

abstract：:Extensor digitorum longus muscles of normal mice (C57BL/10ScSn hereafter called C57) were orthotopically transplanted into dystrophin-deficient mice (mdx) and reciprocally, mdx Extensor digitorum longus muscles were transplanted into C57 mice. After an initial phase of degeneration, transplanted muscles regenerate nea...

journal_title：Journal of muscle research and cell motility

authors： Moens PD,Van-Schoor MC,Maréchal G

更新日期：1996-02-01 00:00:00

abstract：:Protein kinase C (PKC) is known to play important roles in integrin mediated cell spreading. This study investigated the role of PKC during insulin mediated muscle cell spreading, which was independent of integrin alpha5. We found that PKC-alpha becomes active and localise to membrane during insulin mediated cell spre...

journal_title：Journal of muscle research and cell motility

authors： Goel HL,Dey CS

更新日期：2002-01-01 00:00:00

abstract：:Cells isolated from pig urinary bladders and pregnant full term human uteruses were attached longitudinally between a microforce transducer and a length displacement apparatus. Cells were stretched by applying a series of ramp-like length changes of 0.2 s duration and 10.0 microns amplitude at intervals of 15 min. Pas...

journal_title：Journal of muscle research and cell motility

authors： Glerum JJ,Van Mastrigt R,Van Koeveringe AJ

更新日期：1990-10-01 00:00:00

abstract：:Changes in the isoform patterns of myosin heavy chains (MHC) and Ca2+-ATPase (SERCA) were studied in long-term (72 days) denervated slow-twitch soleus muscles of euthyroid and hyperthyroid rabbits. MHC isoforms were separated electrophoretically. SERCA isoforms were assessed by electrophoretic separation of the trypsi...

journal_title：Journal of muscle research and cell motility

authors： Hämäläinen N,Pette D

更新日期：2001-01-01 00:00:00

abstract：:Results were obtained from contracting frog muscles by collecting high quality time-resolved, two-dimensional, X-ray diffraction patterns at the British Synchrotron Radiation Source (SERC, Daresbury, Laboratory). The structural transitions associated with isometric tension generation were recorded under conditions in ...

journal_title：Journal of muscle research and cell motility

authors： Bordas J,Diakun GP,Diaz FG,Harries JE,Lewis RA,Lowy J,Mant GR,Martin-Fernandez ML,Towns-Andrews E

更新日期：1993-06-01 00:00:00

abstract：:Troponin T (TnT) is one of the muscle regulatory proteins and is thought to be related to unique contractile properties in diverse muscles and also to myogenesis. The expression of TnT isoforms in the chicken wing muscles was investigated by two-dimensional gel electrophoresis and immunoblotting with an antiserum agai...

journal_title：Journal of muscle research and cell motility

authors： Miyazaki JI,Akutsu S,Satow N,Hirao C,Yao Y

更新日期：2001-01-01 00:00:00

abstract：:ADF/cofilins disassemble the actin filament and contribute to a wide range of actin dynamics. These proteins are regulated by several factors, including phosphorylation, pH and mechanical forces. Although the cofilin-decorated actin filament structure was published recently, the mechanisms of these regulating factors ...

journal_title：Journal of muscle research and cell motility

authors： Narita A

更新日期：2020-03-01 00:00:00