Septins, a cytoskeletal protein family, with emerging role in striated muscle.

abstract：:Dr. John Gergely passed away on July 26, 2013 after a long and distinguished career. His publications spanned 67 years. He founded the Department of Muscle Research in the Retina Foundation (which later became the Boston Biomedical Research Institute) and served as director for 34 years. Dr. Gergely served on the edit...

journal_title：Journal of muscle research and cell motility

authors： Greaser ML,Potter JD,Thomas DD,Strasburg GM,Lehrer SS,Wang CL,Grabarek Z

更新日期：2013-12-01 00:00:00

abstract：:The in vivo state of assembly of myosin in vertebrate smooth muscle is controversial. In vitro studies on purified smooth muscle myosin show that it is monomeric (10S) under relaxing conditions and filamentous under contraction conditions. Electron microscopic and antibody labelling studies of intact smooth muscles, o...

journal_title：Journal of muscle research and cell motility

authors： Xu JQ,Gillis JM,Craig R

更新日期：1997-06-01 00:00:00

abstract：:A balanced redox status is necessary to optimize force production in contractile apparatus, where free radicals generated by skeletal muscle are involved in some basic physiological processes like excitation-contraction coupling. Protein glutathionylation has a key role in redox regulation of proteins and signal trans...

journal_title：Journal of muscle research and cell motility

authors： Passarelli C,Petrini S,Pastore A,Bonetto V,Sale P,Gaeta LM,Tozzi G,Bertini E,Canepari M,Rossi R,Piemonte F

更新日期：2008-01-01 00:00:00

abstract：:In this study alterations are characterized which occur, in myocardial force development morphological appearance and protein composition, during the development of cardiac hypertrophy and heart failure in monocrotaline (MCT) treated rats. The transition from cardiac hypertrophy to heart failure was studied by compari...

journal_title：Journal of muscle research and cell motility

authors： Korstjens IJ,Rouws CH,van der Laarse WJ,Van der Zee L,Stienen GJ

更新日期：2002-01-01 00:00:00

abstract：:The effects of 2,3-butanedione monoxime (BDM) on contraction characteristics were studied at 5 degrees C in single intact fibres isolated from the tibialis anterior muscle of the frog. The force-velocity relation was determined using the controlled-velocity method in either whole fibres or short fibre segments in whic...

journal_title：Journal of muscle research and cell motility

authors： Bagni MA,Cecchi G,Colomo F,Garzella P

更新日期：1992-10-01 00:00:00

abstract：:The force-velocity (T-V) relation and the force-extension (T1) relation from single fibres isolated from the muscle tibialis anterior of the frog were determined at present times during the rise of tension and the plateau of an isometric tetanus. During the rise of an isometric tetanus the value of V0 (the velocity of...

journal_title：Journal of muscle research and cell motility

authors： Ambrogi-Lorenzini C,Colomo F,Lombardi V

更新日期：1983-04-01 00:00:00

abstract：:Recent studies have revealed unconventional myosin V to be an important actin-based molecular motor involved in vesicular movement. In this paper we report the molecular characterization of the Drosophila myosin V, identified by reverse genetics. The gene encodes a 1792-residue, 207 kDa heavy chain polypeptide which p...

journal_title：Journal of muscle research and cell motility

authors： Bonafé N,Sellers JR

更新日期：1998-02-01 00:00:00

abstract：:Critical illness myopathy (CIM) is associated with severe muscle atrophy and fatigue in affected patients. Apoptotic signaling is involved in atrophy and is elevated in muscles from patients with CIM. In this study we investigated underlying mechanisms of apoptosis-related pathways in muscles with different fiber type...

journal_title：Journal of muscle research and cell motility

authors： Barnes BT,Confides AL,Rich MM,Dupont-Versteegden EE

更新日期：2015-06-01 00:00:00

abstract：:To evaluate a potential regulatory role of the nerve, the distribution and expression of dystrophin, of beta-dystroglycan (43DAG) and adhalin (50DAG), two of the dystrophin-associated proteins and utrophin (dystrophin related protein or DRP) were studied in rat muscles after 2 weeks of denervation. We found that dystr...

journal_title：Journal of muscle research and cell motility

authors： Biral D,Senter L,Salviati G

更新日期：1996-10-01 00:00:00

abstract：:Myosin heavy chain species were investigated during development in avian pectoralis major muscles (type IIB fibres) by high resolution anion-exchange chromatography of the myosin head region, subfragment-1. At 15 days in ovo four distinct fast-type heavy chain species, I, II, III and IV, in order of elution, were iden...

journal_title：Journal of muscle research and cell motility

authors： Rushbrook JI,Weiss C,Yao TT

更新日期：1991-06-01 00:00:00

abstract：:The effect of urocortin (Uro), a recently discovered neuropeptide with selectivity towards corticotropin-releasing hormone type 2 receptor, was tested on whole cell currents expressed by guinea-pig gastric antrum smooth muscle cells. Uro (1 pmol/l-1 nmol/l) caused a concentration-dependent increase of Ca2+-sensitive K...

journal_title：Journal of muscle research and cell motility

authors： Petkova-Kirova PS,Gagov HS,Duridanova DB

更新日期：2000-01-01 00:00:00

abstract：:The effect of changes in hydrostatic pressure (up to 10 MPa) on the maximally calcium-activated tension in glycerinated rabbit psoas fibres has been examined. The steady active tension was depressed by 0.8% per MPa pressure rise. This pressure sensitivity was enhanced by the pressure of millimolar phosphate and depres...

journal_title：Journal of muscle research and cell motility

authors： Fortune NS,Geeves MA,Ranatunga KW

更新日期：1989-04-01 00:00:00

abstract：:Ryanodine receptors (RyRs) are huge homotetrameric Ca2+ release channels localized to the sarcoplasmic reticulum. RyRs are responsible for the release of Ca2+ from the SR during excitation-contraction coupling in striated muscle cells. Recent revolutionary advancements in cryo-electron microscopy have provided a numbe...

journal_title：Journal of muscle research and cell motility

authors： Ogawa H,Kurebayashi N,Yamazawa T,Murayama T

更新日期：2020-02-10 00:00:00

abstract：:Skeletal muscle fibers exhibit plasticity of their physiological and biochemical properties in response to the firing pattern from the innervating motor neuron. In particular, the gene expression pattern generally characteristic of a slow twitch fiber can be induced in a fast twitch fiber by chronic slow fiber type el...

journal_title：Journal of muscle research and cell motility

authors： Shen T,Liu Y,Randall WR,Schneider MF

更新日期：2006-01-01 00:00:00

abstract：:MagFluo-4 fluorescence (Ca2+) transients associated with action potentials were measured in intact muscle fibres, manually dissected from toads ( Leptodactylus insularis ) or enzymatically dissociated from mice. In toads, the decay phase of the Ca2+ transients is described by a single exponential with a time constant ...

journal_title：Journal of muscle research and cell motility

authors： Caputo C,Bolaños P,Gonzalez A

更新日期：2004-01-01 00:00:00

abstract：:Myomesin-I (also known as Skelemin) is a approximately 185 kDa protein, which is highly expressed in striated muscle. It contains the prototypic class-I (type-III fibronectin) and class-II (C2-immunoglobulin) motifs. Previous studies have shown the presence of Myomesin-I at the M-line of the sarcomere, where it is tho...

journal_title：Journal of muscle research and cell motility

authors： Reddy KB,Fox JE,Price MG,Kulkarni S,Gupta S,Das B,Smith DM

更新日期：2008-01-01 00:00:00

abstract：:A confocal microscope was used to investigate the reversible vacuolation of frog skeletal muscle fibres produced by the efflux and entry of glycerol (80-100 mM). The formation, development and disappearance of vacuoles was observed in the fibres by staining simultaneously with two fluorescent membrane probes, RH414 an...

journal_title：Journal of muscle research and cell motility

authors： Krolenko SA,Amos WB,Lucy JA

更新日期：1995-08-01 00:00:00

abstract：:Proteins containing disintegrin domains play a variety of roles in regulating processes involving adhesion, migration and cell type specification during development of many metazoan organisms. Most disintegrin domain containing proteins belong to the ADAM (a disintegrin and a metalloprotease) family of proteins that a...

journal_title：Journal of muscle research and cell motility

authors： Blumberg DD,Ho HN,Petty CL,Varney TR,Gandham S

更新日期：2002-01-01 00:00:00

abstract：:Single muscle fiber sodium dodecyl sulfate polyacrylamide gel-electrophoresis (SDS-PAGE) is a sensitive technique for determining skeletal muscle myosin heavy chain (MHC) composition of human biopsy samples. However, the number of fibers suitable to represent fiber type distribution via this method is undefined. Muscl...

journal_title：Journal of muscle research and cell motility

authors： Murach KA,Bagley JR,McLeland KA,Arevalo JA,Ciccone AB,Malyszek KK,Wen Y,Galpin AJ

更新日期：2016-04-01 00:00:00

abstract：:The phenotypic expression of cardiomyopathy is greatly influenced by extrinsic factors other than intrinsic genetic defects, such as environmental stress. Exercise is assumed to be an important extrinsic factor, since sudden death is sometimes seen during exercise in young patients with hypertrophic cardiomyopathy (HC...

journal_title：Journal of muscle research and cell motility

authors： Tatsuguchi M,Hiratsuka E,Machida S,Nishikawa T,Imamura S,Shimizu S,Nishimura M,Komuro I,Furutani Y,Furutani M,Nagao H,Komatsu K,Kasanuki H,Matsuoka R

更新日期：2004-01-01 00:00:00

abstract：:Much has been written about the effects of aging on reproductive function, especially female fertility. Much less is known about how aging may affect the contractility of the smooth muscle within the uterus, the myometrium. The myometrium is active through a woman's entire life, not just during pregnancy. Here we will...

journal_title：Journal of muscle research and cell motility

authors： Arrowsmith S,Robinson H,Noble K,Wray S

更新日期：2012-08-01 00:00:00

abstract：:The sonic muscle of the oyster toadfish, Opsanus tau, can produce unfused contractions at 300 Hz. Electron microscopy shows a great abundance of the Sarcoplasmic reticulum (SR) in this muscle, but no functional characterization of the capabilities of the SR has been reported. We measured the oxalate-supported Ca2+ upt...

journal_title：Journal of muscle research and cell motility

authors： Feher JJ,Waybright TD,Fine ML

更新日期：1998-08-01 00:00:00

abstract：:The optimal utilization of energy substrates in muscle fibers is of primary importance for muscle contraction and whole body physiology. This study aimed to investigate the age-related changes in some indicators of glucose catabolism and fatty acid oxidation in muscles of growing rabbits. Longissimus lumborum (fast-tw...

journal_title：Journal of muscle research and cell motility

authors： Gondret F,Damon M,Jadhao SB,Houdebine LM,Herpin P,Hocquette JF

更新日期：2004-01-01 00:00:00

abstract：:Rotary-shadowed filamin molecules appear as long, highly flexible rods curved into a variety of configurations. The particles observed were 2.7 nm wide but had contour lengths of either 98 nm or 193 nm. The longer particles are probably end-to-end dimers of the shorter but it is not clear how many polypeptide chains t...

journal_title：Journal of muscle research and cell motility

authors： Castellani L,Offer G,Elliott A,O'Brien EJ

更新日期：1981-06-01 00:00:00

abstract：:The giant molecule titin (also called connectin) provides an elastic connection in the I-band between the Z-disk and A-band of striated muscle. This region is assembled in a tissue-specific way by extensive differential splicing events. We have raised monoclonal antibodies against the two N2-line isoforms of titin and...

journal_title：Journal of muscle research and cell motility

authors： Gautel M,Lehtonen E,Pietruschka F

更新日期：1996-08-01 00:00:00

abstract：:The remodelling of connective tissue components is a fundamental requirement for a number of pivotal processes in cell biology. These may include myoblast migration and fusion during development and regeneration. In other systems, similar biological processes are facilitated by secretion of the matrix metalloproteinas...

journal_title：Journal of muscle research and cell motility

authors： Lewis MP,Tippett HL,Sinanan AC,Morgan MJ,Hunt NP

更新日期：2000-04-01 00:00:00

abstract：:Muscle development involves a complex sequence of time and spatially regulated cellular events leading to the formation of highly specialised syncytial muscle cells displaying a common feature, the capacity of contraction. Analyses of mechanisms controlling muscle development reveals that the main steps of muscle form...

journal_title：Journal of muscle research and cell motility

authors： Maqbool T,Jagla K

更新日期：2007-01-01 00:00:00

abstract：:To study the development of muscle-specific features during myogenesis, we analysed the ultrastructure and voltage-dependent currents of frog embryonic skeletal myocytes maintained in culture for 10 days. The cells were maintained under culture conditions that prevented cell division, fusion and cell contacts with neu...

journal_title：Journal of muscle research and cell motility

authors： Nasledov GA,Katina IE,Terentyev DA,Tomilin NV,Lukyanenko VI

更新日期：1999-08-01 00:00:00

abstract：:The effects of a ramp stretch (amplitude <6% muscle fibre length (L0), speed < 13L0 s(-1)) on twitch tension and twitch tension re-development were examined in intact mammalian (rat) fast and slow muscle fibre bundles. The experiments were done in vitro at 20 degrees C and at an initial sarcomere length of 2.68 microm...

journal_title：Journal of muscle research and cell motility

authors： Mutungi G,Ranatunga KW

更新日期：2001-01-01 00:00:00

abstract：:We investigated the regulatory roles of MgADP and free Ca2+ in isometric tension development in skinned bovine cardiac muscle. We found that, in the relaxed state without free Ca2+, MgADP elicited a sigmoidal increase in active tension, as is the case in skeletal muscle (ADP-contraction). The critical MgADP concentrat...

journal_title：Journal of muscle research and cell motility

authors： Fukuda N,Fujita H,Fujita T,Ishiwata S

更新日期：1998-11-01 00:00:00