Invasion of Toxoplasma gondii occurs by active penetration of the host cell.

abstract：:An analysis of the concanavalinA binding polypeptide components of bovine tongue epithelial desmosomes reveals that in addition to the known desmosomal glycoproteins of 100/115K (the 'desmocollins'), 140K and 160/165K ('desmoglein 1') there is an uncharacterized glycoprotein of 125K (K = Mr x 10(-3). This latter polyp...

journal_title：Journal of cell science

authors： Jones JC

更新日期：1988-02-01 00:00:00

abstract：:Interactions between different cell types can induce distinct contact inhibition of locomotion (CIL) responses that are hypothesised to control population-wide behaviours during embryogenesis. However, our understanding of the signals that lead to cell-type specific repulsion and the precise capacity of heterotypic CI...

journal_title：Journal of cell science

authors： Brayford S,Kenny FN,Hiratsuka T,Serna-Morales E,Yolland L,Luchici A,Stramer BM

更新日期：2019-05-31 00:00:00

abstract：:The highly elongated bristles of Drosophila have proven to be a valuable model system for studying cellular morphogenesis. Extending bristles contain a series of large bundles of actin filaments juxtaposed to the plasma membrane and centrally located microtubules. Models to explain the extension of the bristle have pr...

journal_title：Journal of cell science

authors： Fei X,He B,Adler PN

更新日期：2002-10-01 00:00:00

abstract：:The movement of cells in small groups, or clusters, was studied in vitro using epithelioid cells from Gordon-Kosswig melanomas (from poecelid fish) and time-lapse cinemicrography. Tumour explants cultured on glass yield cell sheets from which groups of cells separate and become independently motile clusters. These clu...

journal_title：Journal of cell science

authors： Kolega J

更新日期：1981-06-01 00:00:00

abstract：:Meiosis is characterized by two chromosome segregation rounds (meiosis I and II), which follow a single round of DNA replication, resulting in haploid genome formation. Chromosome reduction occurs at meiosis I. It relies on key structures, such as chiasmata, which are formed by repair of double-strand breaks (DSBs) be...

journal_title：Journal of cell science

authors： Meyer RE,Algazeery A,Capri M,Brazier H,Ferry C,Aït-Ahmed O

更新日期：2014-11-01 00:00:00

abstract：:Epithelial cell-cell junctions are specialised structures connecting individual cells in epithelial tissues. They are dynamically and functionally linked to the actin cytoskeleton. Disassembly of these junctions is a key event during physiological and pathological processes, but how this influences gene expression is ...

journal_title：Journal of cell science

authors： Busche S,Descot A,Julien S,Genth H,Posern G

更新日期：2008-04-01 00:00:00

abstract：:Casein kinase 1 (CK1) plays central roles in various signal transduction pathways and performs many cellular activities. For many years CK1 was thought to act independently of modulatory subunits and in a constitutive manner. Recently, DEAD box RNA helicases, in particular DEAD box RNA helicase 3 X-linked (DDX3X), wer...

journal_title：Journal of cell science

authors： Dolde C,Bischof J,Grüter S,Montada A,Halekotte J,Peifer C,Kalbacher H,Baumann U,Knippschild U,Suter B

更新日期：2018-01-04 00:00:00

abstract：:During muscle development myosin molecules form symmetrical thick filaments, which integrate with the thin filaments to produce the regular sarcomeric lattice. In Drosophila indirect flight muscles (IFMs) the details of this process can be studied using genetic approaches. The weeP26 transgenic line has a GFP-encoding...

journal_title：Journal of cell science

authors： Orfanos Z,Sparrow JC

更新日期：2013-01-01 00:00:00

abstract：:Uptake of cadmium into cultured cells and its effects on cell growth and DNA synthesis are measured over a range of Cd concentrations of seven orders of magnitude. Cd uptake is found to be proportional to the external Cd concentration and to incubation time over a very broad range of concentrations. At least 200 mmol ...

journal_title：Journal of cell science

authors： von Zglinicki T,Edwall C,Ostlund E,Lind B,Nordberg M,Ringertz NR,Wroblewski J

更新日期：1992-12-01 00:00:00

abstract：:Multivesicular endosomes are present in virtually every eucaryotic cell, where they arise by intra-endosomal budding of the limiting endosomal membrane. Some genetic diseases such as Chediak-Higashi syndrome are characterized by enlarged membrane-filled endosomes. The same altered endosomal morphology can be observed ...

journal_title：Journal of cell science

authors： Marchetti A,Mercanti V,Cornillon S,Alibaud L,Charette SJ,Cosson P

更新日期：2004-12-01 00:00:00

abstract：:Nuclear domains called ND10 or PML nuclear bodies consist of an aggregation of several proteins, most notably PML and Sp100. PML is essential in the nucleation and formation of ND10 as well as in the recruitment of other ND10-associated proteins such as Daxx, pRb, BLM and Sp100. In cells induced to overexpress Sp100, ...

journal_title：Journal of cell science

authors： Negorev D,Ishov AM,Maul GG

更新日期：2001-01-01 00:00:00

abstract：:A mutation in the alpha 1-tubulin gene of Chlamydomonas reinhardtii was isolated by using the amiprophos-methyl-resistant mutation apm1-18 as a background to select new mutants that showed increased resistance to the drug. The upA12 mutation caused twofold resistance to amiprophos-methyl and oryzalin, and twofold hype...

journal_title：Journal of cell science

authors： James SW,Silflow CD,Stroom P,Lefebvre PA

更新日期：1993-09-01 00:00:00

abstract：:Intermediate filament protein keratin 8 (K8) binds to heat shock protein 70 (Hsp70) and p38 MAPK, and is phosphorylated at Ser74 by p38α (MAPK14, hereafter p38). However, a p38 binding site on K8 and the molecular mechanism of K8-p38 interaction related to Hsp70 are unknown. Here, we identify a p38 docking site on K8 ...

journal_title：Journal of cell science

authors： Lee SY,Kim S,Lim Y,Yoon HN,Ku NO

更新日期：2019-09-26 00:00:00

abstract：:In fibroblasts, platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) stimulate the formation of actin-rich, circular dorsal ruffles (CDRs) and phosphatidylinositol 3-kinase (PI3K)-dependent phosphorylation of Akt. To test the hypothesis that CDRs increase synthesis of phosphorylated Akt1 (pAkt), we ...

journal_title：Journal of cell science

authors： Yoshida S,Pacitto R,Sesi C,Kotula L,Swanson JA

更新日期：2018-11-16 00:00:00

abstract：:In primary cultures of rat cerebellar granule cells with a functional network of glutamatergic neurons, the expression pattern of the different subunits of nitric-oxide (NO)-sensitive guanylyl cyclase changes during cell differentiation. These cells express the alpha1, alpha2 and beta1 subunits of NO-sensitive guanyly...

journal_title：Journal of cell science

authors： Jurado S,Sanchez-Prieto J,Torres M

更新日期：2003-08-01 00:00:00

abstract：:Nodal signaling induces the formation of the endoderm and mesoderm during gastrulation. Nodal expression persists until the definitive endoderm progenitor has completely formed, and disappears thereafter. A tightly regulated Nodal expression system is essential for the differentiation of embryonic stem (ES) cells into...

journal_title：Journal of cell science

authors： Takenaga M,Fukumoto M,Hori Y

更新日期：2007-06-15 00:00:00

abstract：:In Saccharomyces cerevisiae, three classes of sphingolipids contain myo-inositol--inositol phosphorylceramide (IPC), mannosylinositol phosphorylceramide (MIPC) and mannosyldiinositol phosphorylceramide [M(IP)(2)C]. No fission yeast equivalent of Ipt1p, the inositolphosphotransferase that synthesizes M(IP)(2)C from MIP...

journal_title：Journal of cell science

authors： Nakase M,Tani M,Morita T,Kitamoto HK,Kashiwazaki J,Nakamura T,Hosomi A,Tanaka N,Takegawa K

更新日期：2010-05-01 00:00:00

abstract：:African trypanosomes undergo extensive changes in cellular morphology, biochemistry and surface antigen expression as they differentiate from their bloodstream form to those forms that colonise the midgut of their tsetse fly vector. If initiated with stumpy-form cells, a non-dividing sub-type of the bloodstream parasi...

journal_title：Journal of cell science

authors： Matthews KR,Gull K

更新日期：1997-10-01 00:00:00

abstract：:The Cep63-Cep152 complex located at the mother centriole recruits Plk4 to initiate centriole biogenesis. How the complex is targeted to mother centrioles, however, is unclear. In this study, we show that Cep57 and its paralog, Cep57l1, colocalize with Cep63 and Cep152 at the proximal end of mother centrioles in both c...

journal_title：Journal of cell science

authors： Zhao H,Yang S,Chen Q,Duan X,Li G,Huang Q,Zhu X,Yan X

更新日期：2020-07-03 00:00:00

abstract：:The forkhead transcription factor FOXN1 is required for normal cutaneous and thymic epithelial development. Mutations in FOXN1 give rise to the nude phenotype in mice, rats and man. However, the genes that are regulated by FOXN1 are unknown. To investigate FOXN1 function we expressed an inducible form of the protein, ...

journal_title：Journal of cell science

authors： Janes SM,Ofstad TA,Campbell DH,Watt FM,Prowse DM

更新日期：2004-08-15 00:00:00

abstract：:Proteins of the Wiskott-Aldrich syndrome protein (WASP) family function as nucleation-promoting factors for the ubiquitously expressed Arp2/3 complex, which drives the generation of branched actin filaments. Arp2/3-generated actin regulates diverse cellular processes, including the formation of lamellipodia and filopo...

journal_title：Journal of cell science

authors： Alekhina O,Burstein E,Billadeau DD

更新日期：2017-07-15 00:00:00

abstract：:It is generally accepted that global translation varies during the cell cycle and is low during mitosis. However, addressing this issue is challenging because it involves cell synchronization, which evokes stress responses that, in turn, affect translation rates. Here, we have used two approaches to measure global tra...

journal_title：Journal of cell science

authors： Stonyte V,Boye E,Grallert B

更新日期：2018-09-03 00:00:00

abstract：:The lymphatic endothelial cell (LEC) fate decision program during development has been described. However, the mechanism underlying the maintenance of differentiated LEC identity remains largely unknown. Here, we show that fibroblast growth factor 2 (FGF2) plays a fundamental role in maintaining a differentiated LEC t...

journal_title：Journal of cell science

authors： Ichise T,Yoshida N,Ichise H

更新日期：2014-02-15 00:00:00

abstract：:Immediately following embryonic cleavage, the cells of Astrephomene have four equal-sized basal bodies, two of which are connected by a striated distal fibre and two striated proximal fibres. The four microtubular rootlets, which alternate between having 3/1 and 2 members, are arranged cruciately. The two basal bodies...

journal_title：Journal of cell science

authors： Hoops HJ,Floyd GL

更新日期：1983-09-01 00:00:00

abstract：:Although many pathogenic copy number variations (CNVs) are associated with neuropsychiatric diseases, few of them have been functionally characterised. Here we report multiple schizophrenia cases with CNV abnormalities specific to unc-51-like kinase 4 (ULK4), a serine/threonine kinase gene. Deletions spanning exons 21...

journal_title：Journal of cell science

authors： Lang B,Pu J,Hunter I,Liu M,Martin-Granados C,Reilly TJ,Gao GD,Guan ZL,Li WD,Shi YY,He G,He L,Stefánsson H,St Clair D,Blackwood DH,McCaig CD,Shen S

更新日期：2014-02-01 00:00:00

abstract：:The role of inhibition of prelamin A processing in the inhibition of DNA synthesis by lovastatin was examined by expressing prelamin A in F9 teratocarcinoma cells. These cells, normally lacking expression of the A/C lamins, were transfected with constructs expressing either prelamin A or mature lamin A and the effect ...

journal_title：Journal of cell science

authors： Sinensky M,McLain T,Fantle K

更新日期：1994-08-01 00:00:00

abstract：:Osh6 and Osh7 are lipid transfer proteins (LTPs) that move phosphatidylserine (PS) from the endoplasmic reticulum (ER) to the plasma membrane (PM). High PS levels at the PM are key for many cellular functions. Intriguingly, Osh6 and Osh7 localize to ER-PM contact sites, although they lack membrane-targeting motifs, in...

journal_title：Journal of cell science

authors： D'Ambrosio JM,Albanèse V,Lipp NF,Fleuriot L,Debayle D,Drin G,Čopič A

更新日期：2020-06-04 00:00:00

abstract：:Collagen binding proteins (CBP) are hydrophobic, cell surface polypeptides, isolated by collagen affinity chromatography. Antibodies to CBPs inhibit the attachment of embryonic chicken heart fibroblasts to native type I collagen fibrils in a dose-dependent manner. The CBP antibodies also induce rounding and detachment...

journal_title：Journal of cell science

authors： Ogle RC,Potts AJ,Yacoe M,Little CD

更新日期：1989-10-01 00:00:00

abstract：:Re-epithelialization of wounded skin is necessary for wound closure and restoration of barrier function and requires directional keratinocyte migration towards the center of the wound. The electric field (EF) generated immediately upon wounding could be the earliest signal keratinocytes receive to initiate directional...

journal_title：Journal of cell science

authors： Pullar CE,Isseroff RR

更新日期：2005-05-01 00:00:00

abstract：:The control of bull spermatozoon flagellar activity has been investigated using direct current injection into the cells through an impaling glass microelectrode. Negative current injection results in a decrease in the flagellar frequency. Flagellar frequencies can be decreased to zero with high negative currents. This...

journal_title：Journal of cell science

authors： O'Day PM,Rikmenspoel R

更新日期：1979-02-01 00:00:00