Short-term cocaine self administration alters striatal gene expression.

abstract：:Orexin/hypocretin neurons of the lateral hypothalamus/perifornical area project to a diverse array of brain regions and are responsive to a variety of psychostimulant drugs. It has been shown that orexin neurons are activated by systemic nicotine administration suggesting a possible orexinergic contribution to the eff...

journal_title：Brain research bulletin

authors： Pasumarthi RK,Fadel J

更新日期：2008-12-16 00:00:00

abstract：:Creutzfeldt-Jakob disease (CJD) and other transmissible spongiform encephalopathies (TSEs) are characterised by the accumulation of a pathological conformer of PrP, named PrPsc. Molecular weight and glycosylation of the protease-resistant core of PrPsc (PrP27-30) are heterogeneous in different forms of TSEs. We analys...

journal_title：Brain research bulletin

authors： Cardone F,Liu QG,Petraroli R,Ladogana A,D'Alessandro M,Arpino C,Di Bari M,Macchi G,Pocchiari M

更新日期：1999-08-01 00:00:00

abstract：:Single units were recorded bilaterally from the caudate nuclei of cats before and after 50 microliter injections of either Merlis solution or L-DOPA (200 microgram) dissolved in Merlis into the left lateral cerebral ventricle. After injection of L-DOPA, but not Merlis solution, there was a period of unit silence in bo...

journal_title：Brain research bulletin

authors： Shellenberger MK,Young DN,Levine MS

更新日期：1977-07-01 00:00:00

abstract：:Massively obese males often show symptoms of hypogonadism, but the mechanism for this is unclear. Increased endogenous opioid inhibition of the hypothalamic GnRH pulse generator resulting in insufficient stimulation of the pituitary gonadotroph has been proposed as a possible mechanism. If this hypothesis is correct, ...

journal_title：Brain research bulletin

authors： Blank DM,Clark RV,Heymsfield SB,Rudman DR,Blank MS

更新日期：1994-01-01 00:00:00

abstract：:It is now generally accepted that adenosine has a neuroprotective role in the central nervous system. Agonists of adenosine such as 2-chloroadenosine (2-ClA) have been shown to be neuroprotective, while antagonists such as 8-phenyltheophylline (8-PT) increase neurotoxicity. However, paradoxical results have been repor...

journal_title：Brain research bulletin

authors： Brooke SM,Sapolsky RM

更新日期：2000-03-01 00:00:00

abstract：:Autophagy is the lysosome-mediated bulk degradation of cellular components for material recycling to maintain cellular homeostasis. Autophagy was initially regarded as a nonselective process, however, recent evidence indicates that this process can in fact be highly selective, especially for targeting and degrading or...

journal_title：Brain research bulletin

authors： Wu MY,Song JX,Wang SF,Cai CZ,Li M,Lu JH

更新日期：2018-03-01 00:00:00

abstract：:Mechanisms underlying shock-induced conditioned fear - a paradigm frequently used to model posttraumatic stress disorder, PTSD - are usually studied shortly after shocks. Some of the brain regions relevant to conditioned fear were activated in all the c-Fos studies published so far, but the overlap between the activat...

journal_title：Brain research bulletin

authors： Tulogdi A,Sörös P,Tóth M,Nagy R,Biró L,Aliczki M,Klausz B,Mikics E,Haller J

更新日期：2012-07-01 00:00:00

abstract：:Ethanol has a pharmacological profile similar to other centrally acting drugs, which facilitate GABAergic transmission. GABA is known to produce its effects by increasing the conductance to Cl- ions. In this study, we have examined the effect of ethanol on GABA-induced 36Cl-influx in primary spinal cord cultured neuro...

journal_title：Brain research bulletin

authors： Ticku MK,Lowrimore P,Lehoullier P

更新日期：1986-07-01 00:00:00

abstract：:In the present study we investigated the effect of electrolytic lesion of the medial septal area (MSA) on the pressor and dipsogenic response to cholinergic activation and angiotensin II (ANGII) injection into the subfornical organ (SFO) in rats. In addition the effect of MSA lesion on the natriuresis, kaliuresis and ...

journal_title：Brain research bulletin

authors： Colombari DS,Haibara AS,Camargo LA,Saad WA,Renzi A,DeLuca LA Jr,Menani JV

更新日期：1994-01-01 00:00:00

abstract：:In precollicular decerebrate cats, the vestibulospinal reflex (VSR) was intermittently recorded from the triceps brachii during sinusoidal roll tilt of the whole animal (at 0.15 Hz, +/- 10 degrees), leading to selective stimulation of labyrinth receptors. This reflex, tested during and after a 3-h period of sustained ...

journal_title：Brain research bulletin

authors： Pompeiano O,Manzoni D,D'Ascanio P,Andre P

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Transcranial near-infrared stimulation (tNIRS) can penetrate the scalp and skull and can reach the superficial layers of the cerebral cortex. In this study, we evaluated whether an 820-nm tNIRS can modulate the excitability of the primary motor cortex (M1) as measured by transcranial magnetic stimulation (TMS...

journal_title：Brain research bulletin

authors： Song P,Han T,Lin H,Li S,Huang Q,Dai X,Wang R,Wang Y

更新日期：2020-02-01 00:00:00

abstract：:Multiple unit activities (MUA) in 307 brainstem sites were recorded by chronically implanted electrodes in cats, using a polygraph with 4 channel MUA recording units. During transition from waking to slow wave sleep, at 15 sites including the medial preoptic area (11), the diagonal band of Broca (2) and medial anterio...

journal_title：Brain research bulletin

authors： Ogawa Y,Kawamura H

更新日期：1988-06-01 00:00:00

abstract：:Chemical preconditioning using the mitochondrial toxin, 3-nitropropionic acid (3-NP) has been reported to induce neuroprotection against subsequent global ischemia. To investigate the underlying mechanisms, Mongolian gerbils were pretreated with either vehicle or 3-NP at the dose of 3 or 10 mg/kg, intraperitoneal, 3 d...

journal_title：Brain research bulletin

authors： Garnier P,Bertrand N,Demougeot C,Prigent-Tessier A,Marie C,Beley A

更新日期：2002-05-01 00:00:00

abstract：:Perinatal exposure to delta 9-THC has been shown to produce effects on brain development. In this study we evaluated the changes induced by maternal exposure to delta 9-THC (5 mg/kg per day) from gestational day 5 to postnatal day 24 in eight discrete brain areas on the central serotoninergic system in both adult male...

journal_title：Brain research bulletin

authors： Molina-Holgado F,Alvarez FJ,Gonzalez I,Antonio MT,Leret ML

更新日期：1997-01-01 00:00:00

abstract：:Bone marrow stromal cells (BMSCs) are promising donor cells for transplantation therapies for a variety of diseases. However, there still lack efficient ways to induce directional differentiation of BMSCs to promote their practical use in transplantation therapy. In this study, we constructed hybrid cells by transferr...

journal_title：Brain research bulletin

authors： Zhou Z,Xu Y,Zhong Q,Zheng J

更新日期：2012-02-10 00:00:00

abstract：:Direct intracellular measurements of excitability changes to injected current were made in 116 cortical neurons of awake cats following antidromic or orthodromic activation by repetitive, 1-6 Hz stimulation of the pes pedunculi. The predominant effect seen in antidromically activated cells was a transient decrease in ...

journal_title：Brain research bulletin

authors： Tzebelikos E,Woody CD

更新日期：1979-09-01 00:00:00

abstract：:The effects of unilateral and bilateral electrolytic lesions of the dorsal raphe nuclei (DRN) of 30-day-old rats, on the spontaneous and induced ovulation, were analyzed. The bilateral lesion and the lesion on the right side of the DRN delayed the age of first vaginal estrous. None of the animals with bilateral lesion...

journal_title：Brain research bulletin

authors： Ayala ME,Rosas P,Dominguez R

更新日期：1994-01-01 00:00:00

abstract：:Chronic social stress and/or pharmacological treatments differentially modulate the expression of c-Fos, a marker of neuronal activity, in subregions of the rat brain. Here, we examined the effect of the atypical antipsychotic Clozapine (Clz) (20 mg/kg/day for 3 weeks) on the neuronal activation pattern of c-Fos prote...

journal_title：Brain research bulletin

authors： Stanisavljević A,Perić I,Bernardi RE,Gass P,Filipović D

更新日期：2019-10-01 00:00:00

abstract：:Changes in dietary habits, including the increased consumption of processed foods, rich in trans fatty acids (TFA), have profound effects on offspring health in later life. Thus, this study aimed to assess the influence of maternal trans fat intake during pregnancy or lactation on anxiety behavior, as well as markers ...

journal_title：Brain research bulletin

authors： Pase CS,Metz VG,Roversi K,Roversi K,Vey LT,Dias VT,Schons CF,de David Antoniazzi CT,Duarte T,Duarte M,Burger ME

更新日期：2021-01-01 00:00:00

abstract：:Although increasing evidence indicates that psychiatric symptoms are crucial characteristic of the early stage of Parkinson's disease (PD) and precede motor impairments, the neuronal firing activity of the basolateral nucleus of the amygdala (BLA) in the psychiatric symptom of PD and the involved mechanism are still u...

journal_title：Brain research bulletin

authors： Chen L,Liu J,Zhang QJ,Feng JJ,Gui ZH,Ali U,Wang Y,Fan LL,Hou C,Wang T

更新日期：2011-07-15 00:00:00

abstract：:Migraine and dizziness are relatively common disorders. Patients with dizziness have a higher incidence of migraines than the general population. The discomfort experienced by these patients is often poorly controlled by medication. However, the pathophysiology of vestibular migraine (VM) remains unclear. We hypothesi...

journal_title：Brain research bulletin

authors： Lee YY,Yang YP,Huang PI,Li WC,Huang MC,Kao CL,Chen YJ,Chen MT

更新日期：2015-07-01 00:00:00

abstract：:This study tests the influence of transcranial magnetic stimulation (TMS) of the posterior parietal cortex (PPC) on the initiation of horizontal and vertical saccades, alone or combined with a predictable divergence. A gap paradigm was used; TMS was applied 100 ms after target onset. TMS of the left PPC increased the ...

journal_title：Brain research bulletin

authors： Vernet M,Yang Q,Daunys G,Orssaud C,Kapoula Z

更新日期：2008-05-15 00:00:00

abstract：:The transcription factor cAMP response element-binding protein (CREB) promotes target DNA transcription in response to cellular stimulation in brain neurons. Phosphorylation of CREB is regulated by a variety of extracellular and intracellular signals. In this study, protein kinase C (PKC)-regulated CREB phosphorylatio...

journal_title：Brain research bulletin

authors： Mao LM,Tang Q,Wang JQ

更新日期：2007-05-30 00:00:00

abstract：:The effects of two diketopiperazines, Cyclo (His-Pro) (CHP) and Cyclo (Asp-Phe) (CAP), on striatal extracellular levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) were examined using in vivo microdialysis in anaesthetized rats. Treatment with ...

journal_title：Brain research bulletin

authors： Kaakkola S,Wurtman RJ

更新日期：1993-01-01 00:00:00

abstract：:Small GTPases of the rho family regulate the extensive rearrangements of the cytoskeleton that characterize neuronal differentiation. Citron kinase is a target molecule for activated rhoA, previously implicated in control of cytokinesis. We have found that, in addition, it could play an important role in modulating th...

journal_title：Brain research bulletin

authors： Di Cunto F,Ferrara L,Curtetti R,Imarisio S,Guazzone S,Broccoli V,Bulfone A,Altruda F,Vercelli A,Silengo L

更新日期：2003-05-30 00:00:00

abstract：:Walker 256 carcinosarcoma cells produce subpleural pulmonary metastases when given intravenously to the Sprague-Dawley rat. The number of metastases increases when the rat is given morphine subsequent to the tumor load. The increase in the number of metastases can be blocked be pretreatment with the opiate antagonist ...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE

更新日期：1986-03-01 00:00:00

abstract：:Aged (25-27 months) Long-Evans female rats were distinguished according to whether they showed no significant impairment (AU), moderate impairment (AMI), or severe impairment (ASI) in a spatial reference-memory task. Young (3-5 months) rats served as controls. Electrically evoked overflow of tritium was assessed in hi...

journal_title：Brain research bulletin

authors： Birthelmer A,Stemmelin J,Jackisch R,Cassel JC

更新日期：2003-05-15 00:00:00

abstract：:Mounting clinical and experimental evidence suggests the gut-brain interplay as a novel important paradigm in translational neuroscience, including the critical role for gut microbiota in modulating brain development and behavior, as well as neuroimmune and neuroendocrine responses. Animal models are an indispensable ...

journal_title：Brain research bulletin

authors： de Abreu MS,Giacomini ACVV,Sysoev M,Demin KA,Alekseeva PA,Spagnoli ST,Kalueff AV

更新日期：2019-05-01 00:00:00

abstract：:Regenerative medicine strategies rely on exogenous cell transplantation and/or endogenous cell stimulation. Biomaterials can help to increase the regenerative potential of cells and biomolecules by controlling transplanted cell fate and provide a local, sustained release of biomolecules. In this review, we describe th...

journal_title：Brain research bulletin

authors： Ho MT,Teal CJ,Shoichet MS

更新日期：2019-05-01 00:00:00

abstract：:A method is described for the isolation and culture of neurons in the adult mammalian brain. The cell could be maintained in primary culture for more than several weeks. Whereas the neurons freshly dissociated from the adult brain did not respond to any of the neurotransmitter substances applied, the neurons regained ...

journal_title：Brain research bulletin

authors： Ogata N,Tatebayashi H

更新日期：1991-11-01 00:00:00