Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments.

abstract：:Ongoing maternal behavior in rats is under the inhibitory influence of opiates. Exposure to drugs of abuse may result in a progressive and enduring enhancement of their reinforcing effects. Little attention has been paid to the possibility that puerperal treatment with morphine may lead to sensitization to this drug, ...

journal_title：Brain research bulletin

authors： Miranda-Paiva CM,Nasello AG,Yin AJ,Felicio LF

更新日期：2001-07-01 00:00:00

abstract：:As nicotinic acetylcholine receptor (nAChR) agonists directly address cholinergic neurotransmission with potential impact on glutamatergic function, they are considered as potential new symptomatic treatment options for Alzheimer's disease compared to the indirectly operating acetylcholinesterase inhibitors such as th...

journal_title：Brain research bulletin

authors： Kroker KS,Moreth J,Kussmaul L,Rast G,Rosenbrock H

更新日期：2013-07-01 00:00:00

abstract：:Neutral, magnesium-stimulated sphingomyelinase and acid sphingomyelinase activities in the neurohypophysis, adenohypophysis and cerebrum of rats given 2.25% NaCl drinking water for 7 or 14 days were compared with the same enzyme activities in the tissues of control animals allowed free access to distilled drinking wat...

journal_title：Brain research bulletin

authors： Guy NC,Clarke JT,Spence MW,Cook HW

更新日期：1983-05-01 00:00:00

abstract：:The alpha-2 adrenoreceptor agonist clonidine in low dose inhibits the release of noradrenaline and aggravates absence seizures. The present study examines properties of two types of spike-wave discharges (SWD) in a genetic model of absence epilepsy, the WAG/Rij rats. After reduction of noradrenergic neurotransmission ...

journal_title：Brain research bulletin

authors： Sitnikova E,van Luijtelaar G

更新日期：2005-01-30 00:00:00

abstract：:Systemically administered human recombinant erythropoietin (EPO) may have the potential to reduce the cognitive and behavioural symptoms of mechanical brain injury. In a series of studies we address this possibility. Previously, we studied the effects of EPO given to fimbria-fornix transected rats at the moment of inj...

journal_title：Brain research bulletin

authors： Mogensen J,Boyd MH,Nielsen MD,Kristensen RS,Malá H

更新日期：2008-09-05 00:00:00

abstract：:The anticonvulsant drug Diazepam (DIA-2 mg/kg b. wt), the nitric oxide (NO) donor L-Arginine (L-Arg-2000 mg/kg b. wt) and the putative nitric oxide synthase (NOS) inhibitor N(G)-Nitro-L-Arginine methyl ester (L-NAME-50 mg/kg b. wt) were used to determine the role of endogenous NO on convulsions induced by picrotoxin (...

journal_title：Brain research bulletin

authors： Jayakumar AR,Sujatha R,Paul V,Puviarasan K,Jayakumar R

更新日期：1999-03-01 00:00:00

abstract：:Electrical stimulation of the periaqueductal gray of the rat's midbrain analgesia leads to an increase in the number of artificial pulmonary metastases from the Walker 256 tumor. In an effort to investigate the influence of the pain suppression system and its associated peptides on this phenomenon, we activated the pa...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE,Lundy J

更新日期：1984-05-01 00:00:00

abstract：:Spinal NMDA receptors contribute to control of the cardiovascular system by the ventrolateral medulla. However, little is known about the contribution of these receptors to suprabulbar regulation of hemodynamics and sympathetic outflow. Hence, the involvement of spinal NMDA receptors in regulation of the cardiovascula...

journal_title：Brain research bulletin

authors： Porter JP

更新日期：1993-01-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) receives a direct retinal projection, which in rats includes substance P (SP)-immunoreactive retinal ganglion cells. While SP has been shown to have neurophysiological effects on SCN cells in Syrian hamsters and rats, it is not known what effects SP in the SCN has on circadian rhythms...

journal_title：Brain research bulletin

authors： Piggins HD,Rusak B

更新日期：1997-01-01 00:00:00

abstract：:Administration of methionine enkephalin (ICV) to rats for 5 days resulted in the development of physical dependence as exemplified by a hypothermic response which peaked 2-8 hours after initiation of withdrawal. Twenty-four hours post-withdrawal, opioid receptor binding was determined in the striatum using a selective...

journal_title：Brain research bulletin

authors： Steece KA,DeLeon-Jones FA,Meyerson LR,Lee JM,Fields JZ,Ritzmann RF

更新日期：1986-08-01 00:00:00

abstract：:To acquire knowledge about the environment two types of learning are necessary: declarative localizatory learning about where environmental cues and the subject are, and procedural learning about how to explore and move around the environment. Experimental data indicate that hippocampal regions are involved in spatial...

journal_title：Brain research bulletin

authors： Leggio MG,Federico F,Neri P,Graziano A,Mandolesi L,Petrosini L

更新日期：2006-10-16 00:00:00

abstract：:The present study examined the changes of extracellular concentration of dopamine and its metabolite homovanillic acid in the striatum, the periaqueductal gray and the dorsal horn of lumbar spinal cord following intraplantar injection of carrageenan. In vivo microdialysis and high-performance liquid chromatography wit...

journal_title：Brain research bulletin

authors： Gao X,Zhang YQ,Zhang LM,Wu GC

更新日期：2001-03-01 00:00:00

abstract：:On the basis of the evidence that approximately 45% of Schaffer collateral boutons are zinc-positive, zinc release from Schaffer collaterals and its action were examined in hippocampal slices. When zinc release from Schaffer collaterals was examined using ZnAF-2, a membrane-impermeable zinc indicator, ZnAF-2 signal in...

journal_title：Brain research bulletin

authors： Takeda A,Nakajima S,Fuke S,Sakurada N,Minami A,Oku N

更新日期：2006-02-15 00:00:00

abstract：:Arachidonic acid [20:4(N-6)] has been implicated in neurological damage induced by cerebral ischaemia. Membrane arachidonate concentrations can be reduced by changes in dietary fat intake. Therefore, in the present study, we have investigated the effects of N-3 fatty acid supplementation on neuronal damage induced by ...

journal_title：Brain research bulletin

authors： Relton JK,Strijbos PJ,Cooper AL,Rothwell NJ

更新日期：1993-01-01 00:00:00

abstract：:The issue of possible neurobiological effects of the electromagnetic field (EMF) exposure is highly controversial. To determine whether electromagnetic field exposure could act as an environmental stimulus capable of producing stress responses, we employed the hippocampus, a sensitive target of electromagnetic radiati...

journal_title：Brain research bulletin

authors： Yang XS,He GL,Hao YT,Xiao Y,Chen CH,Zhang GB,Yu ZP

更新日期：2012-07-01 00:00:00

abstract：:Intelligence depends on the ability of the brain to acquire and apply rules and representations. At the neuronal level these properties have been shown to critically depend on the prefrontal cortex. Here we present, in the context of the Distributed Adaptive Control architecture (DAC), a biologically based model for f...

journal_title：Brain research bulletin

authors： Duff A,Fibla MS,Verschure PF

更新日期：2011-06-30 00:00:00

abstract：:Spinocerebellar ataxia type 2 is caused by a polyglutamine stretch in the protein ataxin-2 that is due to an expansion of a CAG repeat in the spinocerebellar ataxia-2 gene. The function of wild-type ataxin-2 has not been clarified. A widespread distribution of this protein throughout the brain has been reported. We ex...

journal_title：Brain research bulletin

authors： Fusco FR,Viscomi MT,Bernardi G,Molinari M

更新日期：2001-10-01 00:00:00

abstract：:Degeneration of substantia nigra dopaminergic neurons is a key pathological change of Parkinson's disease (PD), and its motor consequences have been widely recognized. Recently, mood disorders associated with PD have begun to attract a great deal of interest, however, their pathogenesis remains unclear. PD is associat...

journal_title：Brain research bulletin

authors： Luo XF,Zhang BL,Li JC,Yang YY,Sun YF,Zhao H

更新日期：2015-01-01 00:00:00

abstract：:We have found that thiamine-deficient (TD) rats show significant impairment of avoidance learning on the 25th day after the start of TD diet, as measured by passive-avoidance task. Administration of physostigmine (0.1 mg/kg, i.p.) from the 14th day after the start of TD diet improved the impairment of avoidance learni...

journal_title：Brain research bulletin

authors： Nakagawasai O,Tadano T,Hozumi S,Tan-No K,Niijima F,Kisara K

更新日期：2000-06-01 00:00:00

abstract：:A number of procedures exist for the experimental induction of sodium appetite. With the exception of a low sodium diet, nearly all of these methods are invasive, requiring injections, surgery, or both. In addition to stimulating intake of concentrated salt, some of them produce substantial side-effects like reduced f...

journal_title：Brain research bulletin

authors： Caloiero VG,Lundy RF

更新日期：2004-07-30 00:00:00

abstract：:The inhibition of excitatory mechanisms by components of low molecular weight, isolated from spiders and solitary wasps, such as, the acyl-polyamines, has demonstrated, on the one hand, neuroprotection potential, and on the other hand, it is well known that some arthropod venom components have convulsant activity. Whi...

journal_title：Brain research bulletin

authors： Ribeiro AM,dos Santos WF,Garcia-Cairasco N

更新日期：2000-08-01 00:00:00

abstract：:We previously reported that a low threshold action of norepinephrine (NE) on the cerebellar circuitry is expressed as an amplification of the inhibitory action of gamma aminobutyric acid (GABA) on Purkinje cell activity. Here we examined the effects of locus coeruleus (LC) stimulation on "off-beam" inhibitions of Purk...

journal_title：Brain research bulletin

authors： Moises HC,Waterhouse BD,Woodward DJ

更新日期：1983-06-01 00:00:00

abstract：:The present work describes a series of experiments designed to examine the possible role of central 5-HT circuits in the control of feeding and drinking in pigeons. Acute effects (within 1 h) of intracerebroventricular (ICV) injections of 5-HT (0, 9.7, 19.4, 38.7, 77.5, 155, and 310 nmol) in 24-h food-deprived (24FD) ...

journal_title：Brain research bulletin

authors： Steffens SM,Casas DC,Milanez BC,Freitas CG,Paschoalini MA,Marino-Neto J

更新日期：1997-01-01 00:00:00

abstract：:The uptake of 3H-2-deoxyglucose (3H-2-DG) in selected brain structures was determined subsequent to electrical stimulation of insular cortex (Ins) and the mediodorsal (MD) nucleus of the thalamus in rabbits. Stimulation of Ins elicited parasympathetic-like responding (i.e., bradycardia and depressor responses); wherea...

journal_title：Brain research bulletin

authors： Buchanan SL,Powell DA

更新日期：1987-10-01 00:00:00

abstract：:Rats with chronic hippocampal electrode implants had afterdischarges induced with electrical stimulus intensities of 115, 200, and 800% of a previously determined threshold. Afterdischarge duration, postictal EEG depression duration, and the duration of postictal electrical hypoexcitability were assessed. After discha...

journal_title：Brain research bulletin

authors： Swartzwelder HS,Wegener ST,Johnson CT,Dyer RS

更新日期：1980-09-01 00:00:00

abstract：:Adaptation of the frog, Rana temporaria, to a white background for 12 hr has resulted in an intense formaldehyde-induced fluorescence (FIF) in the neurons of the preoptic recess organ (PRO), paraventricular organ (PVO), nucleus infundibularis dorsalis (NID) and their basal processes permitting visualization of the PRO...

journal_title：Brain research bulletin

authors： Prasada Rao PD

更新日期：1982-07-01 00:00:00

abstract：:Neonatal hippocampal lesions in rats produce behavioral and neurochemical abnormalities post-puberty that are used in animal models for developmentally linked pathology in schizophrenia. In one model, adult rats exhibit enhanced sensitivity to the locomotor-activating effects of amphetamine, if they had sustained exci...

journal_title：Brain research bulletin

authors： Swerdlow NR,Halim N,Hanlon FM,Platten A,Auerbach PP

更新日期：2001-05-01 00:00:00

abstract：:Prior results (37) showed that morphine pretreatment reduces the escape response of the crab Chasmagnathus to a shadow passing overhead and prevents the acquisition of a long-term habituation. These results were explained by a reduction in the danger signalled by the stimulus, and to test this hypothesis methods other...

journal_title：Brain research bulletin

authors： Tomsic D,Maldonado H,Rakitin A

更新日期：1991-05-01 00:00:00

abstract：:In accordance with the genetic nature of Huntington's disease (HD), transgenic and knock-in mouse models have been developed that have sought to recapitulate the key features of the human condition. To date, only a single rat model has been developed, the tgHD rat that carries 51 CAG repeats. The tgHD rat has many of ...

journal_title：Brain research bulletin

authors： Brooks S,Fielding S,Döbrössy M,von Hörsten S,Dunnett S

更新日期：2009-06-30 00:00:00

abstract：:The topographical distribution of glutamate uptake, GABA uptake, and GAD activity was studied in caudal, intermediate and rostral areas of the nucleus of the solitary tract (NTS), dorsal motor nucleus of the vagus (DMN) and the of the solitary tract (NTS), dorsal motor nucleus of the vagus (DMN) and the hypoglossal nu...

journal_title：Brain research bulletin

authors： Simon JR,DiMicco SK,Aprison MH

更新日期：1985-01-01 00:00:00