Abstract：
:Somatovisceral convergence was demonstrated in recordings from 15 of 16 spinothalamic tract cells in the lower thoracic spinal cords of anesthetized monkeys. Inputs were produced by mechanical (or sometimes electrical) stimulation of the skin over the lower trunk and by electrical stimulation of the greater splanchnic nerve through a buried electrode. The volley in the greater splanchnic nerve was monitored using a buried electrode on the sympathetic chain. Spinothalamic tract cells could be excited by activity in A delta and C fibers, but no effects produced by A beta fibers were noted. In some cases inhibitory effects were observed due to movement of hair on the trunk, and inhibitory interactions could be demonstrated between cutaneous and visceral afferent volleys.
journal_name
Painjournal_title
Painauthors
Foreman RD,Hancock MB,Willis WDdoi
10.1016/0304-3959(81)90002-6subject
Has Abstractpub_date
1981-10-01 00:00:00pages
149-162issue
2eissn
0304-3959issn
1872-6623pii
00006396-198110000-00002journal_volume
11pub_type
杂志文章相关文献
PAIN文献大全abstract：:This report describes a placebo-controlled study of transcutaneous electrical nerve stimulation (TENS) applied to the contralateral lower leg and outer ears of an amputee with non-painful phantom sensations. The subject received TENS or placebo stimulation on separate sessions in which baseline periods of no stimulati...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(89)90098-5
更新日期：1989-03-01 00:00:00
abstract：:We report findings from clinical examination and cutaneous laser stimulation in a 57-year-old male, who suffered from a right-sided postcentral stroke. In this patient, we were able to demonstrate (i) a dissociation of discriminative and affective components of pain perception and, for the first time in humans, (ii) t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00012-3
更新日期：1999-05-01 00:00:00
abstract：:Laser-evoked potentials (LEPs) are acknowledged as the most reliable laboratory tool for assessing thermal and pain pathways. Electrical stimulation with a newly developed planar concentric electrode, delivering stimuli limited to the superficial skin layers, has been suggested to provide selective activation of Aδ fi...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/j.pain.2012.03.004
更新日期：2012-06-01 00:00:00
abstract：:Fifty-seven patients (74%) who had completed a multidisciplinary pain program returned mailed questionnaires assessing both outcome and compliance measures. Significant treatment gains were observed at follow-up. Compliance with prescribed therapeutic regimens was low, averaging around 42% for individual regimens. Com...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(83)90102-1
更新日期：1983-11-01 00:00:00
abstract：:Conditioned pain modulation (CPM) is a phenomenon that may be tested with a dynamic quantitative sensory test that assesses the inhibitory aspect of this pain modulatory network. Although CPM has been adopted as a clinical assessment tool in recent years, the stability of the measure has not been determined over long ...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/j.pain.2013.06.038
更新日期：2013-12-01 00:00:00
abstract：:Mechanical allodynia is pain caused by normally innocuous mechanical stimuli and is a cardinal and intractable symptom of neuropathic pain. Roles of low-threshold mechanoreceptors (LTMRs), including Aβ fibers, in mechanical allodynia have previously been proposed, but the necessity and sufficiency of LTMRs in allodyni...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1097/j.pain.0000000000001506
更新日期：2019-05-01 00:00:00
abstract：:Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish pop...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.07.023
更新日期：2012-12-01 00:00:00
abstract：:A fundamental question for placebo research is whether such responses are a predisposition, quantifiable by brain characteristics. We examine this issue in chronic back pain (CBP) patients who participated in a double-blind brain imaging (functional magnetic resonance imaging) clinical trial. We recently reported that...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2012.08.008
更新日期：2012-12-01 00:00:00
abstract：:Slow-release strong opioids (SRSO) are indicated in patients with severe chronic pain. Side effects, lack of efficacy and risk of dependency limit their use in clinical practice. The aim of this study was to explore prescription patterns of SRSO in Swedish real-world data on patients with a diagnosis related to chroni...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.07.011
更新日期：2012-12-01 00:00:00
abstract：:Late-life depression and pain more often co-occur than can be explained by chance. Determinants of pain in late-life depression are unknown, even though knowledge on possible determinants of pain in depression is important for clinical practice. Therefore, the objectives of the present study were 1) to describe pain c...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2014.07.019
更新日期：2014-10-01 00:00:00
abstract：:Thirty subjects were given a placebo (intravenous saline), which was described as a known pain killer, once a week for 3 consecutive weeks. Experimental ischemic arm pain was produced prior to the placebo and again 1 h later. In a double blind procedure, half of the subjects received 10 mg of naloxone after placebo; t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(83)90203-8
更新日期：1983-06-01 00:00:00
abstract：:Despite decades of research, hundreds of studies, and a number of recent reviews, the effects of aging on the experience of pain remain poorly understood. Many prior investigators have reported increases in persistent pain conditions and diminished tolerance for certain types of laboratory-induced pain among the elder...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(02)00324-x
更新日期：2003-01-01 00:00:00
abstract：:Data from the World Health Organization's study of psychological problems in general health care were used to examine the course of persistent pain syndromes among primary care patients. Across 15 sites in 14 countries, 3197 randomly selected primary care patients completed baseline and 12-month follow-up assessments ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(00)00483-8
更新日期：2001-05-01 00:00:00
abstract：:In recent years, oxytocin has been implicated in a wide diversity of functions. The role of oxytocin in analgesia and pain modulation represents an important new function of an endogenous system controlling sensorial information. The paraventricular (PV) nucleus of the hypothalamus is one of the most important sources...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.01.029
更新日期：2006-05-01 00:00:00
abstract：:We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verify whether it is associated with voltage-gated sodium channel variants. In 57 consecutively enrolled patients with fibro...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001920
更新日期：2020-10-01 00:00:00
abstract：:Fifty adult patients with chronic pain and substance dependence were admitted to an inpatient unit for treatment of addiction without primary emphasis on treatment of pain. As a group they had received considerable medical attention for their pain, but relatively little for their addictions. When compared with a group...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(86)90072-2
更新日期：1986-08-01 00:00:00
abstract：:Visceral pain/discomfort is the cardinal complaints and treatment targets for functional gastrointestinal disorders (FGID). However, effective treatment for such pain is limited and often associated with high placebo effects. The mechanisms of placebo effects in visceral pain are unclear. We used functional neuroimagi...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.pain.2009.10.012
更新日期：2010-01-01 00:00:00
abstract：:Anti-nociceptive tolerance to opioids is a well-described phenomenon, which severely limits the clinical efficacy of opioids for the treatment of chronic pain syndromes. The mechanisms that drive anti-nociceptive tolerance, however, are less well understood. We have previously shown that glia have a central role in th...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2010.02.042
更新日期：2010-09-01 00:00:00
abstract：:Polyneuropathy can be linked to chronic pain but also to reduced pain sensitivity. We investigated peripheral C-nociceptors in painful and painless polyneuropathy patients to identify pain-specific changes. Eleven polyneuropathy patients with persistent spontaneous pain and 8 polyneuropathy patients without spontaneou...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.05.017
更新日期：2012-10-01 00:00:00
abstract：:Pain and thermal sensitivity thresholds in healthy volunteers were examined for diurnal variations. The subjects were 11 men aged between 22 and 27 years (means = 23.5, S.D. = 1.5). Data were collected for 2 days, with 7 measurements per day. To ensure the pain specificity of the results the subliminal modality, i.e.,...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90120-6
更新日期：1989-01-01 00:00:00
abstract：:The aim of this paper is to study the synergistic anti-analgesic effect of angiotensin II (Ang II) plus cholecystokinin octapeptide (CCK-8). Our previous studies have shown that both CCK-8 and Ang II are potent anti-opioid substances. Intracerebroventricular (i.c.v.) injection of CCK-8 or Ang II dose-dependently antag...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(99)00294-8
更新日期：2000-04-01 00:00:00
abstract：:Data on comparative safety of opioid analgesics are limited, but some reports suggest disproportionate mortality risk associated with methadone. Our objective was to compare mortality rates among patients who received prescribed methadone or long-acting morphine for pain. This is a retrospective observational cohort d...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2011.03.023
更新日期：2011-08-01 00:00:00
abstract：:In knee osteoarthritis (OA), pain sensitization has been linked to a more severe symptomatology, but the prognostic implications of pain sensitivity in people undergoing conservative treatment such as physiotherapy are not established. This study aimed to prospectively investigate the association between features of p...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001288
更新日期：2018-09-01 00:00:00
abstract：:Measurement of depression and other mood states in pain patients has been criticised in recent years on the grounds that most questionnaires were not developed in pain populations and suffer from criterion contamination by somatic items. In addition, there is no accepted measurement for positive emotions which are mor...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.02.004
更新日期：2004-05-01 00:00:00
abstract：ABSTRACT:The burden of pain in newborn infants has been investigated in numerous studies, but little is known about the appropriateness of the use of pain scales according to the specific type of pain or infant condition. This systematic review aimed to evaluate the reporting of neonatal pain scales in randomized trial...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000002046
更新日期：2021-02-01 00:00:00
abstract：:The effects of intrathecal administration of substance P and N-methyl-D-aspartate (NMDA) were studied in the formalin test in mice. Both substances were administered 5 min before injection of formalin into the hind paw. Co-administration of substance P and NMDA intensified the response in both the 1st (0-10 min) and t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(92)90260-I
更新日期：1992-11-01 00:00:00
abstract：:Clinical observations and recent studies suggest that arthritis patients vary considerably in their involvement in self-management efforts. In the literature on health promotion, there is growing recognition that patients may be at different stages of change with respect to the adoption of self-management strategies. ...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0304-3959(00)00294-3
更新日期：2000-09-01 00:00:00
abstract：:Tailored treatment based on individual risk factors is an area with promise to improve options for pain relief. Musculoskeletal pain has a biopsychosocial nature, and multiple factors should be considered when determining risk for chronic pain. This study investigated whether subgroups comprised genetic and psychologi...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.0000000000000012
更新日期：2015-01-01 00:00:00
abstract：:Internet-delivered interventions are emerging as a strategy to address barriers to care for individuals with chronic pain. This is the first large multicenter randomized controlled trial of Internet-delivered cognitive-behavioral therapy (CBT) for pediatric chronic pain. Participants included were 273 adolescents (205...
journal_title：Pain
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/j.pain.0000000000000348
更新日期：2016-01-01 00:00:00
abstract：:Hindlimb pain models developed in rats have been transposed to mice, but assumed sciatic nerve neuroanatomic similarities have not been examined. We compared sciatic nerve structural organization in mouse strains (C57BL/6J, DBA/2J, and B6129PF2/J) and rat strains (Wistar, Brown Norway, and Sprague-Dawley). Dissection ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2008.01.016
更新日期：2008-05-01 00:00:00
