Abstract：
ABSTRACT:The burden of pain in newborn infants has been investigated in numerous studies, but little is known about the appropriateness of the use of pain scales according to the specific type of pain or infant condition. This systematic review aimed to evaluate the reporting of neonatal pain scales in randomized trials. A systematic search up to March 2019 was performed in Embase, PubMed, PsycINFO, CINAHL, Cochrane Library, Scopus, and Luxid. Randomized and quasirandomized trials reporting neonatal pain scales were included. Screening of the studies for inclusion, data extraction, and quality assessment was performed independently by 2 researchers. Of 3718 trials found, 352 with 29,137 infants and 22 published pain scales were included. Most studies (92%) concerned procedural pain, where the most frequently used pain scales were the Premature Infant Pain Profile or Premature Infant Pain Profile-Revised (48%), followed by the Neonatal Infant Pain Scale (23%). Although the Neonatal Infant Pain Scale is validated only for acute pain, it was also the second most used scale for ongoing and postoperative pain (21%). Only in a third of the trials, blinding for those performing the pain assessment was described. In 55 studies (16%), pain scales that were used lacked validation for the specific neonatal population or type of pain. Six validated pain scales were used in 90% of all trials, although not always in the correct population or type of pain. Depending on the type of pain and population of infants included in a study, appropriate scales should be selected. The inappropriate use raises serious concerns about research ethics and use of resources.
journal_name
Painjournal_title
Painauthors
Olsson E,Ahl H,Bengtsson K,Vejayaram DN,Norman E,Bruschettini M,Eriksson Mdoi
10.1097/j.pain.0000000000002046subject
Has Abstractpub_date
2021-02-01 00:00:00pages
353-360issue
2eissn
0304-3959issn
1872-6623pii
00006396-202102000-00004journal_volume
162pub_type
杂志文章相关文献
PAIN文献大全abstract：:Mindfulness-based stress reduction (MBSR) is a structured 8-week group program teaching mindfulness meditation and mindful yoga exercises. MBSR aims to help participants develop nonjudgmental awareness of moment-to-moment experience. Fibromyalgia is a clinical syndrome with chronic pain, fatigue, and insomnia as major...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2010.10.043
更新日期：2011-02-01 00:00:00
abstract：ABSTRACT:While knee and hip replacements are intended to relieve pain and improve function, up to 44% of knee replacement patients and 27% of hip replacement patients report persistent postoperative joint pain. Improving surgical pain management is essential. We conducted a single-site, three-arm, parallel-group random...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000002195
更新日期：2021-01-12 00:00:00
abstract：:Mounting evidence suggests that the spinal dorsal horn (SDH) contains multiple subpopulations of inhibitory interneurons that play distinct roles in somatosensory processing, as exemplified by the importance of spinal dynorphin-expressing neurons for the suppression of mechanical pain and chemical itch. Although it is...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001636
更新日期：2019-10-01 00:00:00
abstract：:The proinflammatory cytokines tumor necrosis factor (TNF) α and interleukin (IL) 1β have been strongly implicated in the pathogenesis of neuropathic pain, but the intracellular signaling of these cytokines in glial cells is not fully understood. TNF receptor-associated factor 6 (TRAF6) plays a key role in signal trans...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2014.09.027
更新日期：2014-12-01 00:00:00
abstract：:Dynorphin A is an endogenous opioid peptide, which has previously been shown to produce a long-lasting allodynia and hyperalgesia in mice, behavioral states consistent with signs of clinically observed neuropathic pain. This dynorphin-induced allodynia was used as a pharmacological, central model of neuropathic pain. ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00195-5
更新日期：2000-02-01 00:00:00
abstract：:Cognitive factors are thought to play an important mediational role between pain and consequent levels of suffering, yet there has been little investigation of these issues in older chronic pain patients. The present study sought to examine the reliability and validity of the Pain Locus of Control (PLOC) scale when us...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/S0304-3959(99)00284-5
更新日期：2000-04-01 00:00:00
abstract：:Pro-inflammatory cytokine production after nociceptive stimuli is pivotal for hyperalgesia. As macrophage migration inhibitory factor (MIF), a pleiotropic cytokine produced mainly by nonneuronal tissue, has been involved in the regulation of neuronal functions, herein we examined the role for MIF in formalin-induced i...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.11.011
更新日期：2010-02-01 00:00:00
abstract：:Non-invasive, movement-based models were used to investigate muscle pain. In rats, the masseter muscle was rapidly stretched or electrically stimulated during forced lengthening to produce eccentric muscle contractions (EC). Both EC and stretching disrupted scattered myofibers and produced intramuscular plasma extrava...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2010.02.022
更新日期：2010-05-01 00:00:00
abstract：:After a pilot study had indicated that the topical application of guanethidine might be of value in the treatment of tooth dentine hypersensitivity, a double-blind study was undertaken to investigate whether guanethidine was more effective than a distilled water control in alleviating dentinal pain. In 39 adult subjec...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(93)90205-4
更新日期：1993-08-01 00:00:00
abstract：:We investigated the effects of acute and of chronic morphine treatment on T-lymphocyte function and natural killer (NK) cell activity in rats receiving chronic constriction injury (CCI) of the sciatic nerve. T-Lymphocyte function was evaluated based on concanavalin-A (ConA)- and phytohemagglutinin (PHA)-induced spleno...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(00)00323-7
更新日期：2000-11-01 00:00:00
abstract：:Approximately 70-80% of women meeting criteria for borderline personality disorder (BPD) report attenuated pain perception or analgesia during non-suicidal, intentional self-mutilation. The aim of this study was to use laser-evoked potentials (LEPs) and psychophysical methods to differentiate the factors that may unde...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.04.035
更新日期：2004-07-01 00:00:00
abstract：:The proinflammatory cytokine interferon-gamma (IFN-gamma), which can be present in elevated levels in the central nervous system during pathological conditions, may be involved in the generation of persistent pain states by inducing neuronal hyperexcitability. The aim of the present study was to examine whether loss o...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.02.010
更新日期：2007-12-15 00:00:00
abstract：:Pain patients' retrospective reports of pain are important to physicians and other health professionals in helping to decide on future treatment plans. Unfortunately patients' memory of pain can be inaccurate and subject to overestimation. This study examined variables which influenced accuracy of remembering pain in ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90193-0
更新日期：1989-06-01 00:00:00
abstract：:Patients with neuropathic pain (NP) are challenging to manage and evidence-based clinical recommendations for pharmacologic management are needed. Systematic literature reviews, randomized clinical trials, and existing guidelines were evaluated at a consensus meeting. Medications were considered for recommendation if ...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1016/j.pain.2007.08.033
更新日期：2007-12-05 00:00:00
abstract：:The blood vessels and the pial surface of the brain, spinal cord and its roots are innervated by primary afferent neurones. Here, we have electrophysiologically characterized the functional properties of a subpopulation of these afferent fibres that supply the ventral roots of the cat sacral spinal cord. We have taken...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(91)90167-V
更新日期：1991-04-01 00:00:00
abstract：:A cold pressor task (CPT) was used with 203 college students (112 women and 91 men) in a study of sex differences in pain response. Physiological measures were taken before and after pain induction, and sex-differentiating personality traits were assessed with the Personal Attributes Questionnaire (PAQ). The Pain Cata...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.08.017
更新日期：2004-11-01 00:00:00
abstract：:Supraspinal opioid analgesia is mediated in part by connections between the periaqueductal gray (PAG) and rostral ventromedial medulla (RVM). Morphine analgesia elicited from the PAG is respectively decreased by selective serotonergic and opioid receptor antagonists administered into the RVM, and increased by RVM neur...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00192-1
更新日期：1996-03-01 00:00:00
abstract：:We have constructed and validated the Elderly Pain Caring Assessment 2 (EPCA-2) an 8 items behavioural scale to rate the intensity of pain in non-verbally communicating older (age 65 years) patients (NVC-OP). It was postulated that the assessed pain had two dimensions (signs outside and during caregiving). The first v...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.03.007
更新日期：2007-12-15 00:00:00
abstract：:Chronic and acute pre-mastectomy pain as well as prevalence and characteristics of phantom phenomena following mastectomy were investigated by interview in a sample of 39 women who had undergone unilateral breast amputation. Twenty of 39 participants reported phantom sensations in the breast. Nine of the participants ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2003.10.007
更新日期：2004-01-01 00:00:00
abstract：:Ninety-two knees in 46 patients were evaluated with regard to pain: in 51 of these knees, implantation of a hinged endoprosthesis had been performed. The reliability and validity of 2 pain evaluation methods were assessed: the knee-pain questionnaire method (standard version including 10 questions and modified version...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90069-9
更新日期：1989-07-01 00:00:00
abstract：:Burrowing, an ethologically relevant rodent behaviour, has been proposed as a novel outcome measure to assess the global impact of pain in rats. In a prospective multicentre study using male rats (Wistar, Sprague-Dawley), replication of suppressed burrowing behaviour in the complete Freund adjuvant (CFA)-induced model...
journal_title：Pain
pub_type： 杂志文章,多中心研究
doi：10.1097/j.pain.0000000000000657
更新日期：2016-10-01 00:00:00
abstract：:Chronic pain due to surgery, radiotherapy, or chemotherapy is prevalent in long-term cancer survivors. Chronic pain due to successful cancer treatment should be treated as chronic nonmalignant pain, primarily with nonpharmacological strategies. Based on complete national data from the Cancer Registry of Norway and the...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001459
更新日期：2019-04-01 00:00:00
abstract：:In the last decade, there has been burgeoning interest in the effectiveness of third-generation psychological therapies for managing fibromyalgia (FM) symptoms. The present study examined the effectiveness of acceptance and commitment therapy (ACT) on functional status as well as the role of pain acceptance as a media...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2013.12.029
更新日期：2014-04-01 00:00:00
abstract：:Changes in perception of pure thermal stimuli delivered to the hand at threshold intensity were observed during ischemic nerve block in 27 healthy subjects in order to study the significance of unmyelinated cutaneous cold receptors for thermal sensibility. Paresthesias and an increasing feeling of numbness were follow...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(84)90112-X
更新日期：1984-12-01 00:00:00
abstract：:Vascular head pain is thought to result from activation of trigeminal sensory nerve fibers innervating cranial blood vessels. Support for this hypothesis was sought by searching in the trigeminal brain-stem subnucleus caudalis (SNC) for neuronal responses evoked by electrical stimulation of the middle meningeal artery...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(86)90244-7
更新日期：1986-06-01 00:00:00
abstract：:Spasticity is a major clinical manifestation of spinal cord injury and upper motor neuron syndrome. ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00255-9
更新日期：2000-03-01 00:00:00
abstract：:Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from corti...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.07.007
更新日期：2012-11-01 00:00:00
abstract：:Effects of electrical stimulation of the cervical vagus nerve were determined in cervical or lumbar spinal neurons in 27 rats anesthetized with pentobarbital. Ipsilateral cervical vagus stimulation (ICVS) increased activity of 44 neurons in the C1 segment. At the same stimulation parameters, contralateral cervical vag...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(92)90013-2
更新日期：1992-10-01 00:00:00
abstract：:The aim of the present study was to investigate changes in the plasma calcitonin gene-related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT) content during the immediate headache and the delayed genuine migraine attack provoked by nitroglycerin. Fifteen female migraineurs (without aura...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2003.09.008
更新日期：2003-12-01 00:00:00
abstract：:Extracellular nucleosides and nucleotides have widespread functions in responding to physiological stress. The "purinome" encompasses 4 G-protein-coupled receptors (GPCRs) for adenosine, 8 GPCRs activated by nucleotides, 7 adenosine 5'-triphosphate-gated P2X ion channels, as well as the associated enzymes and transpor...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001857
更新日期：2020-07-01 00:00:00
