An evaluation of sex differences in psychological and physiological responses to experimentally-induced pain: a path analytic description.

Abstract:

:A cold pressor task (CPT) was used with 203 college students (112 women and 91 men) in a study of sex differences in pain response. Physiological measures were taken before and after pain induction, and sex-differentiating personality traits were assessed with the Personal Attributes Questionnaire (PAQ). The Pain Catastrophizing Scale (PCS) was given with standard instructions prior to the CPT, and it was re-administered after the CPT with modified instructions to assess catastrophic thinking during the CPT. Hypotheses were formulated into an explanatory model that was evaluated by path analysis. Pain induction elevated blood pressures and cortisol levels for both sexes, but systolic blood pressure reactivity and cortisol response were greater in men, even with sex differences in CPT tolerance times controlled statistically. Post-CPT PCS scores were positively related to pain ratings and negatively related to tolerance, but baseline PCS scores did not predict tolerance or pain ratings. Pre-PCS scores were not well correlated with post-PCS scores (r=0.46) and underestimated post-PCS scores, particularly for women. The Sex difference on the post-CPT PCS was largely attributable to the PAQ personality trait of Emotional Vulnerability. The differential results obtained from assessing catastrophizing before and after the CPT emphasized the importance of specifying the context in which catastrophizing is assessed (both timing and instructions). Theoretical considerations in the construct of catastrophizing are also highlighted, including, but not limited to, the confounding of variables such as pain intensity and unpleasantness.

journal_name

Pain

journal_title

Pain

authors

Dixon KE,Thorn BE,Ward LC

doi

10.1016/j.pain.2004.08.017

keywords:

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

188-96

issue

1-2

eissn

0304-3959

issn

1872-6623

pii

S0304-3959(04)00411-7

journal_volume

112

pub_type

杂志文章

相关文献

PAIN文献大全
  • Mu- and delta-opioid receptors are downregulated in the largest diameter primary sensory neurons during postnatal development in rats.

    abstract::The aim of this study was to investigate the postnatal development of mu-(MOR) and delta-opioid receptor (DOR) immunoreactivity in rat dorsal root ganglia. Lumbar dorsal root ganglia (DRG) from postnatal day (P) 0, 3, 7 and 21 rat pups were immunostained for MOR and DOR. Proportions of MOR +ve and DOR +ve cells were c...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/s0304-3959(00)00397-3

    authors: Beland B,Fitzgerald M

    更新日期:2001-02-01 00:00:00

  • Ratio scales of sensory and affective verbal pain descriptors.

    abstract::The results of two experiments show that ratio scales of sensory and affective verbal pain descriptors are valid, reliable and objective. In the first experiment, 16 subjects rated 15 sensory and 15 affective verbal pain descriptors by numerical magnitude estimation and by cross-modality matching to handgrip force. Ra...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(78)90020-9

    authors: Gracely RH,McGrath P,Dubner R

    更新日期:1978-06-01 00:00:00

  • The role of developmental factors in predicting young children's use of a self-report scale for pain.

    abstract::Accurate pain assessment is the foundation for effective pain management in children. At present, there is no clear consensus regarding the age at which young children are able to appropriately use self-report scales for pain. This study examined young children's ability to use the Faces Pain Scale-Revised; (FPS-R; [H...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2005.10.004

    authors: Stanford EA,Chambers CT,Craig KD

    更新日期:2006-01-01 00:00:00

  • Long-term maintenance of the analgesic effects of transcranial magnetic stimulation in fibromyalgia.

    abstract::We assessed for the first time the long-term maintenance of repetitive transcranial magnetic stimulation (rTMS)-induced analgesia in patients with chronic widespread pain due to fibromyalgia. Forty consecutive patients were randomly assigned, in a double-blind fashion, to 2 groups: one receiving active rTMS (n=20) and...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2011.01.034

    authors: Mhalla A,Baudic S,de Andrade DC,Gautron M,Perrot S,Teixeira MJ,Attal N,Bouhassira D

    更新日期:2011-07-01 00:00:00

  • Vibratory stimulation for the relief of pain of dental origin.

    abstract::The present paper describes the effect of vibratory stimulation on pain of dental origin in 36 patients. The patients were from a clinic for dental surgery and all had suffered pain from pulpal inflammation, apical periodontitis or postoperative pain following extraction of an impacted wisdom tooth for more than 2 day...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(81)90043-9

    authors: Ottoson D,Ekblom A,Hansson P

    更新日期:1981-02-01 00:00:00

  • High-threshold primary afferent supply of spinal lamina X neurons.

    abstract::The spinal gray matter region around the central canal, lamina X, is critically involved in somatosensory processing and visceral nociception. Although several classes of primary afferent fibers terminate or decussate in this area, little is known about organization and functional significance of the afferent supply o...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001586

    authors: Krotov V,Tokhtamysh A,Safronov BV,Belan P,Voitenko N

    更新日期:2019-09-01 00:00:00

  • Nitric oxide (NO) and nociceptive processing in the spinal cord.

    abstract::There is considerable evidence to implicate N-methyl-D-aspartate (NMDA) receptor activation in the mechanisms that underly thermal hyperalgesia in the spinal cord. As many of the effects of NMDA receptor activation appear to be ultimately mediated through production of nitric oxide (NO), recent reports have begun to d...

    journal_title:Pain

    pub_type: 杂志文章,评审

    doi:10.1016/0304-3959(93)90124-8

    authors: Meller ST,Gebhart GF

    更新日期:1993-02-01 00:00:00

  • A scale to measure pain in non-verbally communicating older patients: the EPCA-2 Study of its psychometric properties.

    abstract::We have constructed and validated the Elderly Pain Caring Assessment 2 (EPCA-2) an 8 items behavioural scale to rate the intensity of pain in non-verbally communicating older (age 65 years) patients (NVC-OP). It was postulated that the assessed pain had two dimensions (signs outside and during caregiving). The first v...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2007.03.007

    authors: Morello R,Jean A,Alix M,Sellin-Peres D,Fermanian J

    更新日期:2007-12-15 00:00:00

  • Pain and placebo in pediatrics: a comprehensive review of laboratory and clinical findings.

    abstract::Pain modulation by placebo mechanisms is one of the most robust and best-studied phenomena, yet almost all research investigating the mechanisms and implications of the placebo analgesia are based on adult research. After highlighting crucial aspects that need to be considered in studying pain modulation in children, ...

    journal_title:Pain

    pub_type: 杂志文章,评审

    doi:10.1016/j.pain.2014.08.036

    authors: Simmons K,Ortiz R,Kossowsky J,Krummenacher P,Grillon C,Pine D,Colloca L

    更新日期:2014-11-01 00:00:00

  • Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene.

    abstract::Pain is a complex human trait. It is likely that the interaction of multiple genes, each with a small individual effect, along with the effect of environmental factors, influences the clinical efficacy of opioids rather than a single gene alone. Polymorphisms in genes coding for the mu-opioid receptor (A118G) and cate...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2006.10.023

    authors: Reyes-Gibby CC,Shete S,Rakvåg T,Bhat SV,Skorpen F,Bruera E,Kaasa S,Klepstad P

    更新日期:2007-07-01 00:00:00

  • A complete national cohort study of prescriptions of analgesics and benzodiazepines to cancer survivors in Norway 10 years after diagnosis.

    abstract::Chronic pain due to surgery, radiotherapy, or chemotherapy is prevalent in long-term cancer survivors. Chronic pain due to successful cancer treatment should be treated as chronic nonmalignant pain, primarily with nonpharmacological strategies. Based on complete national data from the Cancer Registry of Norway and the...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001459

    authors: Fredheim OM,Skurtveit S,Handal M,Hjellvik V

    更新日期:2019-04-01 00:00:00

  • A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain.

    abstract::A preliminary report of clinical study revealed that chronic discogenic low back pain could be treated by intradiscal methylene blue (MB) injection. We investigated the effect of intradiscal MB injection for the treatment of chronic discogenic low back pain in a randomized placebo-controlled trial. We recruited 136 pa...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2010.01.021

    authors: Peng B,Pang X,Wu Y,Zhao C,Song X

    更新日期:2010-04-01 00:00:00

  • Peripheral nerve injury and sensitization underlie pain associated with oral cancer perineural invasion.

    abstract::Cancer invading into nerves, termed perineural invasion (PNI), is associated with pain. Here, we show that oral cancer patients with PNI report greater spontaneous pain and mechanical allodynia compared with patients without PNI, suggesting that unique mechanisms drive PNI-induced pain. We studied the impact of PNI on...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001986

    authors: Salvo E,Campana WM,Scheff NN,Nguyen TH,Jeong SH,Wall I,Wu AK,Zhang S,Kim H,Bhattacharya A,Janal MN,Liu C,Albertson DG,Schmidt BL,Dolan JC,Schmidt RE,Boada MD,Ye Y

    更新日期:2020-11-01 00:00:00

  • Are both the sensory and the affective dimensions of pain encoded in the face?

    abstract::The facial expression of pain plays a crucial role in pain communication and pain diagnostics. Despite its importance, it has remained unknown which dimensions of pain (sensory and/or affective) are encoded in the face. To answer this question, we used a well-established cognitive strategy (suggestions) to differentia...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2011.10.027

    authors: Kunz M,Lautenbacher S,LeBlanc N,Rainville P

    更新日期:2012-02-01 00:00:00

  • Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain - results from the EPIFUND study.

    abstract::Chronic widespread pain (CWP) is associated with poor health-related quality of life (HRQoL). It is unclear whether pain itself is the cause of poor HRQoL or other factors play a role. We hypothesised that new onset of CWP was associated with poor physical and mental HRQoL but that psychosocial risk markers for CWP on...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2008.10.022

    authors: Nicholl BI,Macfarlane GJ,Davies KA,Morriss R,Dickens C,McBeth J

    更新日期:2009-01-01 00:00:00

  • Estrogen and progesterone activate spinal kappa-opiate receptor analgesic mechanisms.

    abstract::Rats and humans manifest elevated response thresholds to aversive stimuli during gestation and parturition. This pregnancy-associated antinociception is mediated, in part, by a spinal cord dynorphin/kappa antinociceptive system. Simulating the maternal pregnancy blood concentration profile (in non-pregnant animals) of...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(95)00092-5

    authors: Dawson-Basoa ME,Gintzler AR

    更新日期:1996-01-01 00:00:00

  • Magnetic resonance imaging contribution for diagnosing symptomatic neurovascular contact in classical trigeminal neuralgia: a blinded case-control study and meta-analysis.

    abstract::Although classical trigeminal neuralgia (CTN) is frequently caused by neurovascular contact (NVC) at the trigeminal root entry zone (REZ), both anatomical and MRI studies have shown that NVC of the trigeminal nerve frequently occurs in individuals without CTN. To assess the accuracy of MRI in distinguishing symptomati...

    journal_title:Pain

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.pain.2014.04.020

    authors: Antonini G,Di Pasquale A,Cruccu G,Truini A,Morino S,Saltelli G,Romano A,Trasimeni G,Vanacore N,Bozzao A

    更新日期:2014-08-01 00:00:00

  • Chronic stress-associated visceral hyperalgesia correlates with severity of intestinal barrier dysfunction.

    abstract::In humans, chronic psychological stress is associated with increased intestinal paracellular permeability and visceral hyperalgesia, which is recapitulated in the chronic intermittent water avoidance stress (WAS) rat model. However, it is unknown whether enhanced visceral pain and permeability are intrinsically linked...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001271

    authors: Creekmore AL,Hong S,Zhu S,Xue J,Wiley JW

    更新日期:2018-09-01 00:00:00

  • Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine.

    abstract::A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression. Treatment was given, in randomized order, for periods of 4 weeks, separated by 1 week wash-o...

    journal_title:Pain

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0304-3959(89)90108-5

    authors: Leijon G,Boivie J

    更新日期:1989-01-01 00:00:00

  • A comprehensive categorical and bibliometric analysis of published research articles on pediatric pain from 1975 to 2010.

    abstract::The field of pediatric pain research began in the mid-1970s and has undergone significant growth and development in recent years as evidenced by the variety of books, conferences, and journals on the topic and also the number of disciplines engaged in work in this area. Using categorical and bibliometric meta-trend an...

    journal_title:Pain

    pub_type: 历史文章,杂志文章,评审

    doi:10.1097/j.pain.0000000000000403

    authors: Caes L,Boerner KE,Chambers CT,Campbell-Yeo M,Stinson J,Birnie KA,Parker JA,Huguet A,Jordan A,MacLaren Chorney J,Schinkel M,Dol J

    更新日期:2016-02-01 00:00:00

  • The formalin test in mice: effect of formalin concentration.

    abstract::The effect of different formalin concentrations on the nociceptive response in the formalin test was examined in mice. Subcutaneous formalin injection induces 2 distinct periods of high licking activity: an early phase lasting the first 5 min, and a late phase lasting 20-30 min after the injection. Formalin concentrat...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(90)91167-H

    authors: Rosland JH,Tjølsen A,Mæhle B,Hole K

    更新日期:1990-08-01 00:00:00

  • Electrical stimulation of tooth pulp in humans. I. Relationships among physical stimulus intensities, psychological magnitude estimates and cerebral evoked potentials.

    abstract::Brief electrical pulses were applied to the pulp of individual pre-molar teeth of 14 healthy, adult volunteers via wire electrodes implanted and sealed in dentine. The sensation threshold was estimated in each individual by the Two-Alternative Forced-Choice Staircase (2AFCS) method. Seven, 5 or 4 stimulus intensities ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(82)90130-0

    authors: Fernandes de Lima VM,Chatrian GE,Lettich E,Canfield RC,Miller CR,Soso MJ

    更新日期:1982-11-01 00:00:00

  • Cerebral analgesic response to nonsteroidal anti-inflammatory drug ibuprofen.

    abstract::Nonopioid agents, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are the most commonly used class of analgesics. Increasing evidence suggests that cyclooxygenase (COX) inhibition at both peripheral and central sites can contribute to the antihyperalgesic effects of NSAIDs, with the predominant clinical effect ...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/j.pain.0000000000000176

    authors: Hodkinson DJ,Khawaja N,O'Daly O,Thacker MA,Zelaya FO,Wooldridge CL,Renton TF,Williams SCR,Howard MA

    更新日期:2015-07-01 00:00:00

  • Trigeminal neuralgia and atypical facial pain: use of the McGill Pain Questionnaire for discrimination and diagnosis.

    abstract::Although trigeminal neuralgia and atypical facial pain can usually be distinguished on the basis of several well-established criteria, differential diagnosis is difficult in a small number of patients. The purpose of this study was to determine whether the McGill Pain Questionnaire (MPQ) is capable of discriminating b...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(86)90157-0

    authors: Melzack R,Terrence C,Fromm G,Amsel R

    更新日期:1986-12-01 00:00:00

  • Oxytocin and electrical stimulation of the paraventricular hypothalamic nucleus produce antinociceptive effects that are reversed by an oxytocin antagonist.

    abstract::In recent years, oxytocin has been implicated in a wide diversity of functions. The role of oxytocin in analgesia and pain modulation represents an important new function of an endogenous system controlling sensorial information. The paraventricular (PV) nucleus of the hypothalamus is one of the most important sources...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2006.01.029

    authors: Miranda-Cardenas Y,Rojas-Piloni G,Martínez-Lorenzana G,Rodríguez-Jiménez J,López-Hidalgo M,Freund-Mercier MJ,Condés-Lara M

    更新日期:2006-05-01 00:00:00

  • Vagal afferent fibers excite upper cervical neurons and inhibit activity of lumbar spinal cord neurons in the rat.

    abstract::Effects of electrical stimulation of the cervical vagus nerve were determined in cervical or lumbar spinal neurons in 27 rats anesthetized with pentobarbital. Ipsilateral cervical vagus stimulation (ICVS) increased activity of 44 neurons in the C1 segment. At the same stimulation parameters, contralateral cervical vag...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(92)90013-2

    authors: Qing-Gong F,Chandler MJ,McNeill DL,Foreman RD

    更新日期:1992-10-01 00:00:00

  • Multiple roles for NaV1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease-derived stimuli.

    abstract::Chronic visceral pain affects millions of individuals worldwide and remains poorly understood, with current therapeutic options constrained by gastrointestinal adverse effects. Visceral pain is strongly associated with inflammation and distension of the gut. Here we report that the voltage-gated sodium channel subtype...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2014.06.015

    authors: Hockley JR,Boundouki G,Cibert-Goton V,McGuire C,Yip PK,Chan C,Tranter M,Wood JN,Nassar MA,Blackshaw LA,Aziz Q,Michael GJ,Baker MD,Winchester WJ,Knowles CH,Bulmer DC

    更新日期:2014-10-01 00:00:00

  • Nitrous oxide inhibits glutamatergic transmission in spinal dorsal horn neurons.

    abstract::The effects of nitrous oxide (N2O) are thought to be mediated by several pharmacological pathways at different levels of the central nervous system. Here, we focus on excitatory glutamatergic transmission in the superficial dorsal horn of the spinal cord with respect to its importance for the nociceptive processing. T...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2007.03.026

    authors: Georgiev SK,Kohno T,Ikoma M,Yamakura T,Baba H

    更新日期:2008-01-01 00:00:00

  • The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.

    abstract::To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes. Sixty-one patients (42 with fibromyalgia (FM) and 19 with myofascial pain syndrome (MPS)) completed the trial. Outcome measures included pain intensity...

    journal_title:Pain

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0304-3959(94)00232-4

    authors: Scudds RA,Janzen V,Delaney G,Heck C,McCain GA,Russell AL,Teasell RW,Varkey G,Woodbury GM

    更新日期:1995-07-01 00:00:00

  • Intratrigeminal ganglionic injection of LPA causes neuropathic pain-like behavior and demyelination in rats.

    abstract::We have previously reported a novel method for producing chronic nociceptive behavior in rats following compression of the trigeminal ganglion. In the present study, we have further studied the role of demyelination in the development of prolonged nociceptive behavior in the trigeminal territory. For this purpose, lys...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2009.07.012

    authors: Ahn DK,Lee SY,Han SR,Ju JS,Yang GY,Lee MK,Youn DH,Bae YC

    更新日期:2009-11-01 00:00:00