Abstract:
:Brief electrical pulses were applied to the pulp of individual pre-molar teeth of 14 healthy, adult volunteers via wire electrodes implanted and sealed in dentine. The sensation threshold was estimated in each individual by the Two-Alternative Forced-Choice Staircase (2AFCS) method. Seven, 5 or 4 stimulus intensities were employed which were equally spaced in a logarithmic scale between 10 microA above threshold and 500 microA. Magnitude estimates of the subjective intensity of the sensation produced by individual dental excitations were obtained. Cerebral tooth pulp-evoked potentials were simultaneously recorded in 11 subjects. The growth of psychological sensory magnitude with increasing strength of electrical stimulus conformed to the general psychophysical power law. Individual power function exponents varied from 0.204 to 0.907 with a mean of 0.475 and a standard deviation of 0.190. The amplitude of TPEPs, measured between components N135 and P293, also was a power function of stimulus intensity. The exponents of individual TPEP amplitude-intensity functions ranged from 0.055 to 0.362 with a mean of 0.144 and a standard deviation of 0.100. These last exponents were substantially smaller than those describing the growth of psychological magnitude estimates. Neither magnitude estimation nor TPEP amplitude-intensity functions displayed abrupt changes in slope which might accompany transition from one operating sensory mechanism to another and/or changes in qualities of subjective sensations from 'innocuous' to 'uncomfortable' to 'painful.' The result of our psychophysical and electrophysiologic experiments indicate that: (1) albeit highly specialized both morphologically and functionally, human tooth pulp has certain fundamental properties in common with other sensory systems and (2) late midline TPEP components may provide measures of central events that, within a range of stimulus intensities, are associated with the perception of pain, but should not be looked upon as specific indicators of pain processes.
journal_name
Painjournal_title
Painauthors
Fernandes de Lima VM,Chatrian GE,Lettich E,Canfield RC,Miller CR,Soso MJdoi
10.1016/0304-3959(82)90130-0subject
Has Abstractpub_date
1982-11-01 00:00:00pages
207-232issue
3eissn
0304-3959issn
1872-6623pii
00006396-198211000-00002journal_volume
14pub_type
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