Treatment outcome and compliance with therapeutic regimens: long-term follow-up of a multidisciplinary pain program.

abstract：:It is well known that acupuncture has pain-relieving effects, but the contribution of specific and especially nonspecific factors to acupuncture analgesia is less clear. One hundred one patients who developed pain of ≥ 3 on a visual analog scale (VAS, 0 to 10) after third molar surgery were randomized to receive activ...

journal_title：Pain

authors： Vase L,Baram S,Takakura N,Yajima H,Takayama M,Kaptchuk TJ,Schou S,Jensen TS,Zachariae R,Svensson P

更新日期：2013-09-01 00:00:00

abstract：:Inflammatory thermal hyperalgesia is principally mediated through transient receptor potential vanilloid 1 (TRPV1) channels, as demonstrated by prior studies using models of cutaneous inflammation. Muscle pain is significantly different from cutaneous pain, and the involvement of TRPV1 in hyperalgesia induced by muscl...

journal_title：Pain

authors： Walder RY,Radhakrishnan R,Loo L,Rasmussen LA,Mohapatra DP,Wilson SP,Sluka KA

更新日期：2012-08-01 00:00:00

abstract：:This research was designed to identify and validate facial expressions of pain occurring in a clinical chronic pain condition. Facial expressions of 28 patients with chronic temporomandibular disorder pain were videotaped during a painful clinical examination procedure and coded using an anatomically based system. Cha...

journal_title：Pain

authors： LeResche L,Dworkin SF

更新日期：1988-10-01 00:00:00

abstract：:We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verify whether it is associated with voltage-gated sodium channel variants. In 57 consecutively enrolled patients with fibro...

journal_title：Pain

authors： Fasolino A,Di Stefano G,Leone C,Galosi E,Gioia C,Lucchino B,Terracciano A,Di Franco M,Cruccu G,Truini A

更新日期：2020-10-01 00:00:00

abstract：:Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity, and poorer response to treatment. Genetic factors acting in an age-specific manner have been implicated but never comprehensively explored. We performed sex- and age-stratified genome-wide assoc...

journal_title：Pain

authors： Freidin MB,Tsepilov YA,Stanaway IB,Meng W,Hayward C,Smith BH,Khoury S,Parisien M,Bortsov A,Diatchenko L,Børte S,Winsvold BS,Brumpton BM,Zwart JA,Aulchenko YS,Suri P,Williams FMK,HUNT All-In Pain.

更新日期：2020-09-30 00:00:00

abstract：:The induction of hyperalgesia upon capsaicin administration requires activation of specific sub-classes of nociceptive afferent C-fibres providing nociceptive input to the central nervous system. It has been demonstrated in animal models that the endocannabinoid anandamide has anti-hyperalgesic properties upon capsaic...

journal_title：Pain

authors： Rukwied R,Watkinson A,McGlone F,Dvorak M

更新日期：2003-04-01 00:00:00

abstract：:The literature on cognitive and cognitive-behavioral methods for pain control is selectively reviewed, with particular focus on controlled studies. Such methods include the provision of preparatory information, cognitive coping skills or strategies, the provision of preparatory information plus some form of coping ski...

journal_title：Pain

authors： Tan SY

更新日期：1982-03-01 00:00:00

abstract：:Although trigeminal neuralgia and atypical facial pain can usually be distinguished on the basis of several well-established criteria, differential diagnosis is difficult in a small number of patients. The purpose of this study was to determine whether the McGill Pain Questionnaire (MPQ) is capable of discriminating b...

journal_title：Pain

authors： Melzack R,Terrence C,Fromm G,Amsel R

更新日期：1986-12-01 00:00:00

abstract：:The purpose of this study was to determine if some commonly used admission variables could predict treatment outcome on a multidisciplinary pain center. Specifically, it was designed as a prospective study of an index proposed by Maruta et al. The subjects were 104 patients. The 4 outcome measures used were staff judg...

journal_title：Pain

authors： Aronoff GM,Evans WO

更新日期：1982-09-01 00:00:00

abstract：:We assessed nimodipine's ability to increase the analgesic effect of morphine in 32 patients suffering from cancer pain in a double-blind, placebo controlled cross-over study. Morphine administration began a few days before the start of the study. The analgesic effects of two combinations were compared: morphine (M) p...

journal_title：Pain

authors： Roca G,Aguilar JL,Gomar C,Mazo V,Costa J,Vidal F

更新日期：1996-12-01 00:00:00

abstract：:Dysmenorrhea is the most prevalent gynecological disorder in women of child-bearing age. Dysmenorrhea is associated with central sensitization and functional and structural changes in the brain. Our recent brain morphometry study disclosed that dysmenorrhea is associated with trait-related abnormal gray matter (GM) ch...

journal_title：Pain

authors： Tu CH,Niddam DM,Yeh TC,Lirng JF,Cheng CM,Chou CC,Chao HT,Hsieh JC

更新日期：2013-09-01 00:00:00

abstract：:A portable constant current electrical stimulator with bipolar felt disk electrodes was developed for quantitative assessment of cutaneous sensibility. The new method was used in the measurement of thresholds for perception and pain in healthy volunteers. The mean values of the threshold for perception in different ar...

journal_title：Pain

authors： Laitinen LV,Eriksson TA

更新日期：1985-06-01 00:00:00

abstract：:Pediatric chronic pain is associated with numerous negative outcomes including increased physical disability, increased rates of depression and anxiety, and decreased quality of life (QOL). Pain catastrophizing-broadly conceptualized as including rumination, magnification, and helplessness cognitions surrounding one's...

journal_title：Pain

authors： Miller MM,Meints SM,Hirsh AT

更新日期：2018-12-01 00:00:00

abstract：:Iatrogenic Cushing's syndrome has been reported after the use of nasal, aerosol, oral, and intramuscular steroid preparations. Presented is a case of Cushing's syndrome due to an epidural injection of methylprednisolone. A 24-year-old man had left arm pain after an occupational injury. Electromyography revealed C7 rad...

journal_title：Pain

authors： Tuel SM,Meythaler JM,Cross LL

更新日期：1990-01-01 00:00:00

abstract：:Part I of our earlier pilot study demonstrated that patients preferred modulated stimulation forms - frequency modulation and burst - rather than conventional continuous mode. To assess whether long-term therapeutic effects validate the immediate test results, this trial was performed in 14 patients with 21 pain condi...

journal_title：Pain

authors： Tulgar M,McGlone F,Bowsher D,Miles JB

更新日期：1991-11-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanisms of referred pain observed in female patients with pain from the reproductive organs. We developed a model of inflammatory uterine pain in the rat. Inflammation of the uterus in rats pretreated with Evans Blue Dye resulted in dye extravasation in the skin over...

journal_title：Pain

authors： Wesselmann U,Lai J

更新日期：1997-12-01 00:00:00

abstract：:Tibia fracture induces exaggerated substance P (SP) and calcitonin gene-related peptide (CGRP) signaling and neuropeptide-dependent nociceptive and inflammatory changes in the hind limbs of rats similar to those seen in complex regional pain syndrome. Inflammatory changes in the spinal cord contribute to nociceptive s...

journal_title：Pain

authors： Shi X,Guo TZ,Wei T,Li WW,Clark DJ,Kingery WS

更新日期：2015-10-01 00:00:00

abstract：:The habituation to sensory stimuli of different modalities is reduced in migraine patients. However, the habituation to pain has never been evaluated. Our aim was to assess the nociceptive pathway function and the habituation to experimental pain in patients with migraine. Scalp potentials were evoked by CO(2) laser s...

journal_title：Pain

authors： Valeriani M,de Tommaso M,Restuccia D,Le Pera D,Guido M,Iannetti GD,Libro G,Truini A,Di Trapani G,Puca F,Tonali P,Cruccu G

更新日期：2003-09-01 00:00:00

abstract：:Microglia-neuron signalling in the spinal cord is a key mediator of mechanical allodynia caused by peripheral nerve injury. We recently reported sex differences in microglia in pain signalling in mice: spinal mechanisms underlying nerve injury-induced allodynia are microglial dependent in male but not female mice. Whe...

journal_title：Pain

authors： Mapplebeck JCS,Dalgarno R,Tu Y,Moriarty O,Beggs S,Kwok CHT,Halievski K,Assi S,Mogil JS,Trang T,Salter MW

更新日期：2018-09-01 00:00:00

abstract：:Several studies have implicated a potential role for histamine H(3) receptors in pain processing, although the data are somewhat conflicting. In the present study we investigated the effects of the novel potent and highly selective H(3) receptor antagonists GSK189254 (6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepi...

journal_title：Pain

authors： Medhurst SJ,Collins SD,Billinton A,Bingham S,Dalziel RG,Brass A,Roberts JC,Medhurst AD,Chessell IP

更新日期：2008-08-15 00:00:00

abstract：:The effect of PF-04457845, a potent and selective fatty acid amide hydrolase-1 (FAAH1) inhibitor, on pain due to osteoarthritis of the knee was investigated in a randomised placebo and active-controlled clinical trial. The trial involved 2 periods (separated by a 2-week washout) consisting of a 1-week wash-in phase fo...

journal_title：Pain

authors： Huggins JP,Smart TS,Langman S,Taylor L,Young T

更新日期：2012-09-01 00:00:00

abstract：:The present study describes a new test of tonic pain to be used as an animal model of persistent pain. First, pain responses and edema produced by subcutaneous injection of increasing doses of honey bee venom into the hind paw of the rat were quantified. Second, the effect of morphine and aspirin on the pain responses...

journal_title：Pain

authors： Lariviere WR,Melzack R

更新日期：1996-08-01 00:00:00

abstract：:Ten patients who suffered from severe cancer-related pain participated in a randomised, double-blind and cross-over study to compare the effectiveness and acceptability of epidural and subcutaneous administration of morphine. The patients titrated themselves pain-free in 48 h using a patient controlled analgesia syste...

journal_title：Pain

authors： Kalso E,Heiskanen T,Rantio M,Rosenberg PH,Vainio A

更新日期：1996-10-01 00:00:00

abstract：:A chronic compression of the dorsal root ganglion (CCD) produces ipsilateral cutaneous hyperalgesia and allodynia in rats. Intracellular electrophysiological recordings from formerly compressed neurons in the intact dorsal root ganglion (DRG) reveal lower than normal current thresholds (CTs) and abnormal spontaneous a...

journal_title：Pain

authors： Ma C,LaMotte RH

更新日期：2005-01-01 00:00:00

abstract：:A cold pressor task (CPT) was used with 203 college students (112 women and 91 men) in a study of sex differences in pain response. Physiological measures were taken before and after pain induction, and sex-differentiating personality traits were assessed with the Personal Attributes Questionnaire (PAQ). The Pain Cata...

journal_title：Pain

authors： Dixon KE,Thorn BE,Ward LC

更新日期：2004-11-01 00:00:00

abstract：:Distinct developmental trajectories for neck disability and posttraumatic stress disorder (PTSD) symptoms after whiplash injury have recently been identified. This study aimed to identify baseline predictors of membership to these trajectories and to explore their dual development. In a prospective study, 155 individu...

journal_title：Pain

authors： Sterling M,Hendrikz J,Kenardy J

更新日期：2011-06-01 00:00:00

abstract：:Anxiety has been described as an important comorbidity in patients suffering from chronic pain. However, in animals the connection between persistent pain and anxiety has hardly been investigated. Therefore, in the current study it was assessed whether chronic pain also causes anxiety-like behaviour in animals and if ...

journal_title：Pain

authors： Roeska K,Doods H,Arndt K,Treede RD,Ceci A

更新日期：2008-10-15 00:00:00

abstract：:Chronic visceral pain affects millions of individuals worldwide and remains poorly understood, with current therapeutic options constrained by gastrointestinal adverse effects. Visceral pain is strongly associated with inflammation and distension of the gut. Here we report that the voltage-gated sodium channel subtype...

journal_title：Pain

authors： Hockley JR,Boundouki G,Cibert-Goton V,McGuire C,Yip PK,Chan C,Tranter M,Wood JN,Nassar MA,Blackshaw LA,Aziz Q,Michael GJ,Baker MD,Winchester WJ,Knowles CH,Bulmer DC

更新日期：2014-10-01 00:00:00

abstract：:In response to an earlier published paper by Fordyce, some assumptions underlying the behavior management paradigm of chronic pain are critically discussed. While operant treatment has proved successful, the conclusion that operant factors play an important role in the development and maintenance of chronic benign pai...

journal_title：Pain

authors： Schmidt AJM

更新日期：1987-09-01 00:00:00

abstract：:The ability to sense and respond to thermal stimuli at varied environmental temperatures is essential for survival in seasonal areas. In this study, we show that mice respond similarly to ramping changes in temperature from a wide range of baseline temperatures. Further investigation suggests that this ability to adap...

journal_title：Pain

authors： Brenner DS,Golden JP,Vogt SK,Dhaka A,Story GM,Gereau RW IV

更新日期：2014-10-01 00:00:00