Cytologic problems in diagnosis of endocervical atypia in young females with and without maternal history of diethylstilbestrol exposure.

Abstract:

:Sixteen cytologic endocervical atypias are reported with corroborative tissue analysis. Maternal diethylstilbestrol (DES) history was positive in three patients, one with clear cell adenocarcinoma, one with colposcopy and biopsy proven benign vaginal adenosis, and one with squamous carcinoma in situ of the cervix. Colposcopy was performed in two cases, one with adenosis and one with clear cell adenocarcinoma.In three patients, aged 19, 17, and 25, respectively, clear cell adenocarcinomas were found with unknown DES history and positive cytology. In five other cytologically positive cases, endocervicitis was found in three, atypical endocervical hyperplasia in one, and severe squamous dysplasia in one. This represents a cytologic false positive or specificity reading error of 37 percent in this type of material. One case of clear cell adenocarcinoma was linked with DES exposure.In the six suspicious and borderline cytologic reports, one vaginal adenosis, one condyloma acuminata, and one squamous carcinoma in situ were found. This represents a false positive or specificity reading error rate of 43 percent.Cytology is clinically valuable in Proven cases of vaginal adenosis or adenocarcinoma. It is not a diagnostic modality, with a high sensitivity error (false-negative rates) of 50 percent and higher, as reported in the literature and high specificity error (false-positive rates) as herein reported.

journal_name

J Natl Med Assoc

authors

Chenoweth B,Rodney MB

subject

Has Abstract

pub_date

1978-12-01 00:00:00

pages

925-30

issue

12

eissn

0027-9684

issn

1943-4693

journal_volume

70

pub_type

杂志文章
  • Cure rates in small cell and non-small cell carcinoma of the lung utilizing high-dose radiotherapy and chemotherapy.

    abstract::From 1967 to 1977, 72 patients with small cell carcinoma of the lung were seen. Thirty-five of these patients had unilaterally localized lesions (limited disease) and were treated with cobalt 60 radiation therapy (6,000 rad in six weeks) followed by chemotherapy consisting of cyclophosphamide (Cytoxan), vincristine, m...

    journal_title:Journal of the National Medical Association

    pub_type: 临床试验,杂志文章

    doi:

    authors: Akbiyik N,Alexander LL

    更新日期:1986-03-01 00:00:00

  • Time management: a review for physicians.

    abstract::This article reviews the basic concepts and techniques of time management as they relate to a medical lifestyle. Essential tools are described to help the physician reassess and sharpen skills for handling intensifying demands and constraints of juggling patient care, research, teaching, and family responsibilities. T...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,评审

    doi:

    authors: Brunicardi FC,Hobson FL

    更新日期:1996-09-01 00:00:00

  • Cultural sensitivity and readability of breast and prostate printed cancer education materials targeting African Americans.

    abstract::Cancer prevention materials such as pamphlets, booklets, and fact sheets play a significant role in reducing cancer disparities. Little is documented in the literature about the cultural sensitivity of materials targeting African Americans. The Cancer Prevention Materials and African Americans project was conducted to...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Guidry JJ,Fagan P,Walker V

    更新日期:1998-03-01 00:00:00

  • Status epilepticus after baclofen withdrawal.

    abstract::Baclofen is widely used in the treatment of spasticity of spinal origin. It is relatively free of side effects or toxic actions on the nervous system or other organs. Agitation, personality change, and auditory and visual hallucinations have been described following its abrupt withdrawal. One patient with generalized ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Hyser CL,Drake ME Jr

    更新日期:1984-05-01 00:00:00

  • Respondent-Driven Sampling in a Multi-Site Study of Black and Latino Men Who Have Sex with Men.

    abstract:PURPOSE:Respondent-driven sampling (RDS) was used to recruit four samples of Black and Latino men who have sex with men (MSM) in three metropolitan areas to measure HIV prevalence and sexual and drug use behaviors. We compared demographic and behavioral risk characteristics of participants across sites, assessed the ex...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:10.1016/j.jnma.2015.12.009

    authors: Murrill CS,Bingham T,Lauby J,Liu KL,Wheeler D,Carballo-Diéguez A,Marks G,Millett GA

    更新日期:2016-02-01 00:00:00

  • Medicine and science in the 19th and 20th centuries.

    abstract::The achievements of 19th century medical education, practice, literature, and science and their affect on 20th century medicine are reviewed. The contributions made by 19th century physicians to change medical education are described, as well as the social processes that influenced medicine and science in both centuri...

    journal_title:Journal of the National Medical Association

    pub_type: 历史文章,杂志文章

    doi:

    authors: Bloch H

    更新日期:1988-02-01 00:00:00

  • Clear Lensectomy, Goniosynechiolysis and Hydrus Microstent in a Patient with Mixed Mechanism Glaucoma.

    abstract:PURPOSE:To report a case of a patient with mixed mechanism glaucoma and a clear lens who was successfully surgically treated with combination cataract extraction, goniosynechiolysis and the Hydrus stent. OBSERVATION:A 59-year-old Afro-Latino woman with a history of mixed mechanism glaucoma. She was taking latanoprost ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:10.1016/j.jnma.2020.04.003

    authors: Laroche D,Brown A,Ng C

    更新日期:2020-08-01 00:00:00

  • Effectiveness of a social marketing media campaign to reduce oral cancer racial disparities.

    abstract:OBJECTIVES:The purpose of this study was to provide a systematic evaluation of a theory-driven oral cancer awareness media campaign. METHODS:We surveyed a cohort of residents in an intervention city (250) and a control city (250) immediately prior to and after the media campaign. Participants (125 black/African Americ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:10.1016/s0027-9684(15)31005-1

    authors: Watson JM,Tomar SL,Dodd V,Logan HL,Choi Y

    更新日期:2009-08-01 00:00:00

  • Strongyloides duodenitis: case report and review of literature.

    abstract::Strongyloides stercoralis affects 30 to 100 million people worldwide and is a common cause of abdominal pain and diarrhea. Strongyloidiasis is a chronic and limited disease; however, in immunocompromised patients, hyperinfection syndrome can occur. Diagnosing strongyloidiasis early is important, as almost all deaths d...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,评审

    doi:10.1016/s0027-9684(15)30246-7

    authors: Kakati B,Dang S,Heif M,Caradine K,McKnight W,Aduli F

    更新日期:2011-01-01 00:00:00

  • Early detection of pregnancy.

    abstract::Early detection of pregnancy offers many advantages for the fetus and the mother. Many medical benefits depend on early detection, including social and emotional well-being and the aviodance of medicationss, irradiation, and other teratogencis. In the past, women became aware of their pregnancies only when organogen...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Poma PA

    更新日期:1984-03-01 00:00:00

  • Characterization of frequent douchers attending a community clinic primarily serving African-American women.

    abstract:OBJECTIVE:The purpose of this study is to characterize African-American women attending a community clinic who report frequent douching (douching > or = 2 times per week). METHODS:A consecutive sample of 115 black women attending a community clinic were interviewed face-to-face about their douching practices. Logistic...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Smith LV,Rudy ET,Ivie SD,Lee D,Visscher B,Kerndt P

    更新日期:2005-10-01 00:00:00

  • The NIMH Diagnostic Interview Schedule: a test of its validity in a population of black adults.

    abstract::This article examines the validity of the National Institute of Mental Health Diagnostic Interview Schedule (DIS) relative to three of its measures: alcoholism, depression, and schizophrenia when compared with the clinical interview. Preliminary results indicate that greater diagnostic agreement was observed for alcoh...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Hendricks LE,Bayton JA,Collins JL,Mathura CB,McMillan SR,Montgomery TA

    更新日期:1983-07-01 00:00:00

  • Evaluating HIV/AIDS disparities for blacks in the United States: a review of antiretroviral and mortality studies.

    abstract::The purpose of this systematic review was to identify studies that evaluated HIV/AIDS disparities by examining differences in the receipt of antiretroviral therapy and differences in mortality between blacks and whites in the United States. The authors conducted 2 Web-based literature searches of the MEDLINE database ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,评审

    doi:10.1016/s0027-9684(15)31133-0

    authors: Oramasionwu CU,Brown CM,Lawson KA,Ryan L,Frei CR

    更新日期:2009-12-01 00:00:00

  • A response to history: a review of one medical school's efforts to graduate minority physicians.

    abstract::The number of minority physician graduates depends upon both the recruitment and retention of physician manpower. Numbers cannot be increased until the problems of recruiting and retaining minority students are minimized. This paper describes the process by which one medical school initiated changes to overcome barrie...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Bruhn JG

    更新日期:1978-11-01 00:00:00

  • Pneumomediastinum and retroperitoneal air after removal of papillomas with the microdebrider and jet ventilation.

    abstract:OBJECTIVE:To discuss the complication of pneumothorax from alveolar rupture after transtracheal high-frequency jet ventilation and to present a case of pneumothorax, pneumomediastinum and pneumoperitoneum after jet ventilation coupled with use of the microdebrider. METHOD:Detailed case report. RESULTS:Unilateral pnue...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Sims HS,Lertsburapa K

    更新日期:2007-09-01 00:00:00

  • Enlarged spleen syndrome.

    abstract::Enlarged spleen without a clear-cut etiology, and believed to be related to malarial infestations, has been referred to as "tropical splenomegaly" and "cryptogenetic splenomegaly." Splenectomy performed in such cases after a failure of antimalarial therapy shows histopathologically, while some of these meet the criter...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Ajao OG

    更新日期:1980-04-01 00:00:00

  • Doctors--who are they?

    abstract::The title "Doctor" has an interesting and not commonly understood inception, and those entitled to use the accolade Doctor have had an interesting evolution. The title is now used by a plethora of individuals with a variety of skills and levels of achievement. A random survey of the population reveals that the public ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Hrisomalos NF

    更新日期:1987-11-01 00:00:00

  • A pilot study to evaluate awareness of and attitudes about prenatal and neonatal genetic testing in postpartum African American women.

    abstract:OBJECTIVE:A pilot study to determine whether prenatal and neonatal sickle cell tests conform to the guidelines established by the American Congress of Obstetricians and Gynecologists and the American Academy of Pediatrics. METHODS:The project was initially structured as a pair of in-person interviews of postpartum wom...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0027-9684(15)30089-4

    authors: Kusyk D,Acharya K,Garvey K,Ross LF

    更新日期:2013-04-01 00:00:00

  • The role of the experience and expression of anger and anxiety in elevated blood pressure among black and white adolescents.

    abstract::Differences between black and white adolescents in the experience and expression of anger and anxiety, traditional risk factors for hypertension, and blood pressure were examined among adolescents enrolled in a health science course in Tampa, Florida. Relationships between blood pressure and anger/anxiety and traditio...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Johnson EH

    更新日期:1989-05-01 00:00:00

  • Race and kidney disease: role of social and environmental factors.

    abstract::Numerous studies have documented the presence of racial disparities among Americans in health outcomes with respect to cardiovascular disease, infant mortality, cancer, and kidney disease. With regard to kidney diseases, these disparities are more dramatic. African, Hispanic, and Native Americans have the highest risk...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,评审

    doi:

    authors: Nzerue CM,Demissochew H,Tucker JK

    更新日期:2002-08-01 00:00:00

  • Colorectal cancer screening of African Americans by internal medicine resident physicians can be improved with focused educational efforts.

    abstract::Colorectal cancer causes significant morbidity and mortality in the United States. African Americans are disproportionately affected by this malignancy. There is evidence to suggest that resident physicians inconsistently screen for colorectal cancer in African Americans, perhaps because of a deficiency in knowledge a...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Friedman M,Borum ML

    更新日期:2007-09-01 00:00:00

  • Pharmacogenomics and Opioid Use Disorder: Clinical Decision Support in an African American Cohort.

    abstract::Opioid use disorder (OUD) constitutes a significant public health burden as opioid overdose deaths have continued to rise in the United States. Although treatment modalities are available to manage OUD, some patients experience challenges achieving their OUD management goals. Some of these challenges may be attributab...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:10.1016/j.jnma.2019.09.006

    authors: Ettienne EB,Ofoegbu A,Maneno MK,Briggs J,Ezeude G,Williams S,Walker C,Chapman E

    更新日期:2019-12-01 00:00:00

  • Evolving perspectives on the exposure risks from magnetic fields.

    abstract::Based on information from suggesting effects of positive and negative polarity on cancer cells, surveys were performed on magnetic resonance imaging devices, as well as other types of equipment capable of producing appreciable magnetic fields. These surveys were performed in areas where there was a potential for both ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Trappier A,Lorio P,Johnson LP

    更新日期:1990-09-01 00:00:00

  • Frequency and characteristics of ocular trauma in an urban population.

    abstract::All patients presenting with ocular trauma to the emergency room of a large inner-city hospital during a 2-month period were prospectively examined and interviewed. Of 3,627 trauma visits, ocular trauma accounted for 126 (3%). There were 514 trauma admissions; 26 (5%) of these were for ocular trauma. Bilateral injurie...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Wilson MR,Wooten F,Williams J

    更新日期:1991-08-01 00:00:00

  • Advanced skin cancer in Tanzanian albinos: preliminary observations.

    abstract::Ten cases of advanced squamous cell carcinoma of the skin in albinos, treated by radiotherapy from 1973 to 1979 at the Muhimbili Medical Center of Dar-es-Salaam, have been reviewed. Age, sex, duration of symptoms, anatomic distribution, stage of disease, and treatment are reviewed. The relationship between albinism, s...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Alexander GA,Henschke UK

    更新日期:1981-11-01 00:00:00

  • Breast and cervical cancer screening among low-income women: impact of a simple centralized HMO intervention.

    abstract::In 1994, it was estimated that about 44,500 American women would die from breast cancer and 7000 women from cervical cancer. While early detection methods (screening mammography, breast examinations, and pap smears) have proven to be effective means of decreasing these cancers, they are underused by all groups. In par...

    journal_title:Journal of the National Medical Association

    pub_type: 临床试验,杂志文章

    doi:

    authors: Hardy RE,Eckert C,Hargreaves MK,Belay Y,Jones TN,Cebrun AJ

    更新日期:1996-06-01 00:00:00

  • Syndrome of multiple jaw cysts, skeletal anomalies, and basal cell nevi: report of a case.

    abstract::A Nigerian school boy with the syndrome of multiple jaw cysts, skeletal anomalies, and basal cell nevi is described and discussed. To the authors' knowledge, this is the first report of this syndrome in a black African. ...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Daramola JO,Komolafe OF,Ajagbe HA,Lawoyin DO

    更新日期:1980-03-01 00:00:00

  • Thoracic aortic dissection in a patient with autosomal dominant polycystic kidney disease.

    abstract::Autosomal dominant polycystic kidney disease is one of the most common hereditary diseases, and frequently has well defined extrarenal manifestations. Very few cases of aortic aneurysms associated with this disorder are described in literature. We report a 42-year-old male with autosomal dominant polycystic kidney dis...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章,评审

    doi:

    authors: Adeola T,Adeleye O,Potts JL,Faulkner M,Oso A

    更新日期:2001-07-01 00:00:00

  • Primary malignant small bowel tumors: an atypical abdominal emergency.

    abstract::Primary malignant tumors of the small bowel are uncommon in the United States. They comprise less than 1% of all gastrointestinal malignancies, with an incidence of 2200 cases per year. The clinical presentation of small bowel tumors is frequently insidious and often overlooked by physicians. The low incidence and lac...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: Mitchell KJ,Williams ES,Leffall LD Jr

    更新日期:1995-04-01 00:00:00

  • The relationship between health status and blood pressure in urban African Americans.

    abstract::African Americans have higher rates of hypertension and poorer health status than their white counterparts. This study assessed the relationship between health status, cardiovascular risk factors, and measured blood pressure. Free blood pressure screenings were performed at businesses and organizations located in west...

    journal_title:Journal of the National Medical Association

    pub_type: 杂志文章

    doi:

    authors: DeForge BR,Stewart DL,DeVoe-Weston M,Graham L,Charleston J

    更新日期:1998-11-01 00:00:00