Abstract:
:Group B streptococci (GBS) have been infrequently recognized as a cause of pharyngitis. We report three cases of GBS pharyngitis in patients with underlying diseases, two of whom were treated with and responded incompletely to oral beta-lactam antibiotics. The susceptibility of 20 clinical isolates of GBS was tested by a broth dilution method to six antibiotics which could conceivably be used in the therapy of GBS pharyngitis. Penicillin G, clindamycin, and erythromycin were most active with mean minimal inhibitory concentrations (MIC) of 0.06 μg/ml or less. Rifampin and cefaclor were least active with mean MICs of 0.71 ug/ml or more. Ampicillin was intermediate in its activity. Therapy traditionally used for Group A streptococcal (GAS) pharyngitis may, at times, be suboptimal for GBS pharyngitis in compromised patients. This may be due to higher minimal bactericidal concentrations (MBC) of GBS than GAS, to inadequate penetration of penicillins into pharyngeal tissues or to host factors. It is suggested that GBS can cause pharyngitis in adults, particularly the compromised patient, and that in cases where there is a poor response to penicillin or ampicillin therapy, alternative drugs (erythromycin or clindamycin) may be used.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Corrado ML,Palmadessa DJ,Corrado SH,Weissman C,Cherubin CE,Landesman SHsubject
Has Abstractpub_date
1981-10-01 00:00:00pages
943-7issue
10eissn
0027-9684issn
1943-4693journal_volume
73pub_type
杂志文章abstract::It is now well documented that substantial disparities exist in the quality and quantity of medical care received by minority Americans, especially those of African, Asian and Hispanic heritage. In addition, the special needs and responses to pharmaceutical treatment of these groups have been undervalued or ignored. T...
journal_title:Journal of the National Medical Association
pub_type: 杂志文章,评审
doi:
更新日期:2002-10-01 00:00:00
abstract::Strangulated right Richter's inguinal hernia of the cecum is relatively rare. A case of this unusual hernia was successfully managed with a wedge resection and closure of the infarcted bowel wall in conjunction with complementary tube cecostomy. The procedure is easy to perform and relatively safe and is therefore rec...
journal_title:Journal of the National Medical Association
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
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更新日期:1994-11-01 00:00:00
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更新日期:1983-11-01 00:00:00
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更新日期:2003-12-01 00:00:00
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更新日期:2005-04-01 00:00:00
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journal_title:Journal of the National Medical Association
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更新日期:1978-09-01 00:00:00
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更新日期:2006-10-01 00:00:00
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journal_title:Journal of the National Medical Association
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更新日期:1992-02-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
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更新日期:2010-01-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
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更新日期:1977-11-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 历史文章,杂志文章
doi:
更新日期:2004-08-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
doi:
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journal_title:Journal of the National Medical Association
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更新日期:2006-05-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
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journal_title:Journal of the National Medical Association
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journal_title:Journal of the National Medical Association
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更新日期:1992-11-01 00:00:00
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journal_title:Journal of the National Medical Association
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更新日期:1979-09-01 00:00:00
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journal_title:Journal of the National Medical Association
pub_type: 杂志文章
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更新日期:1980-08-01 00:00:00
abstract::A 5-year-old boy with purpura fulminans (PF) was successfully managed with a protocol in which fresh frozen plasma (FFP) was administered, followed by a trial of certain therapeutic agents. This approach was based upon combined experience both with the reference patient and with a subject with a chronic form of PF. FF...
journal_title:Journal of the National Medical Association
pub_type: 临床试验,杂志文章
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更新日期:1983-08-01 00:00:00
abstract::Organizational barriers play a key role in colorectal cancer (CRC) screening disparities in low-income minorities. This is a prospective, randomized trial to determine whether a patient navigator (PN) can help overcome the organizational barriers low-income minorities face in trying to obtain screening colonoscopy. Pa...
journal_title:Journal of the National Medical Association
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2008-03-01 00:00:00