Immunosuppressive therapy of ocular disease.

Abstract:

:Care and caution are required in using immunosuppressive agents to combat sight-threatening ocular disease. Informed consent of the patient and the active participation of a knowledgeable internist are mandatory in view of the known potential consequences of therapy. These consequences or side effects include specific and general problems, and before initiating therapy the cost/benefit ratio must be considered. Although the most commonly used agents are nonspecific, some drugs appear more beneficial in certain conditions than others, as is the case of chlorambucil in Behcet disease. It is a policy at the Uveitis Clinic of the University of California, Irvine, to institute immunosuppressive therapy early enough for conservation of useful vision, yet late enough so that it is clear that moderate to heavy steroid therapy cannot prevent blindness. In the event of failure of the "conventional" immunosuppressive therapy, plasmapheresis may prove a helpful adjunct.

journal_name

J Natl Med Assoc

authors

Boone WB,Slater L

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

837-8

issue

9

eissn

0027-9684

issn

1943-4693

journal_volume

71

pub_type

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