Abstract：
:Total hemolytic complement (CH50) and activation of the alternate mechanism were measured in eight patients before and after splenectomy and compared to similar measurements made in a control group of patients following other abdominal surgery. In the splenectomy group, alternate-pathway-mediated activation of C3 was significantly different from the controls. The mean five-day postsplenectomy value of 16 percent for the immunoelectrophoretic conversion of C3 to C3i was depressed (p<0.001) from the presplenectomy value of 85 percent and five-month postsplenectomy level of 71 percent (p<0.01). The difference between presplenectomy and five-month postsplenectomy values was not significant. Further, activation of C3 in patients five days postsplenectomy was significantly less (p<0.01) than in the five-day postoperative controls. In both the splenectomized patients and control group, five-day postoperative determinations indicated an increase in CH50 values and a decrease in degree of activation of Factor B. The spleen appears to manufacture certain substances required for activation of C3 via the alternate mechanism. That the manufacture is eventually assumed by other immune-competent organs is shown by the eventual increase of activation toward preoperative levels five months postsplenectomy. This defect in C3 activation may account for the tendency of splenectomized patients to have an increased incidence of bacterial infections and sepsis in the postoperative period.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
de Ciutiis A,Polley MJ,Metakis LJ,Peterson CMsubject
Has Abstractpub_date
1978-09-01 00:00:00pages
667-70issue
9eissn
0027-9684issn
1943-4693journal_volume
70pub_type
杂志文章abstract：:African Americans are less likely than European Americans to participate in biomedical research. Researchers often attribute nonparticipation to the "Tuskegee effect." Using critical qualitative analysis of focus group data, we examined the public's use of the Tuskegee Study of Untreated Syphilis (TSUS) to discuss bio...
journal_title：Journal of the National Medical Association
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-08-01 00:00:00
abstract：:A patient with thymoma metastatic to bone is presented. The case differs radiographically and pathologically from one previously reported case in which the diagnosis was made during life. The diagnosis was obtained by percutaneous needle biopsy under fluoroscopic control. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1979-08-01 00:00:00
abstract：BACKGROUND:Dental caries is a big public health problem which is prevalent in the highest degree worldwide, especially in lower socioeconomic levels. This study aims to investigate the anti-caries effects of Curcumin in Turmeric on the caries model of enamel under laboratory conditions. METHODS:In order to make a reli...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.12.005
更新日期：2018-10-01 00:00:00
abstract：:Increasing attention has been given to the investigation of cardiovascular disease in women, although African-American women have received little attention. This study compares characteristics and outcomes in women admitted to coronary care units for suspected acute myocardial infarction (MI). Between January 1988 and...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:Swainsonine, an indolizidine alkaloid with immunomodulatory activity, has been found to be effective in inhibiting metastatic dissemination and growth of primary tumors of both murine and human origins. The unique ability of swainsonine to exhibit antimetastatic, anti-proliferative, and immunomodulatory activity impar...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：:This study was undertaken to clarify the complex relationship between poverty and race with disease-specific mortality. Data from the 1987 National Health Interview Survey and the 1986 National Mortality Followback Survey were used to estimate standardized mortality ratios (SMRs) for various categories (all causes, al...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:The purpose of this report is to review personal experience with digital palpation of the nasopharynx, particularly as it relates to an apparently reversible posterior pharyngeal mass commonly found in patients who are heavy smokers. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:Invasive techniques continue to be used in monitoring and treating the critically ill patient in spite of preference for, and increasing use of, non-invasive or minimally invasive techniques. With or without simultaneous determination of left ventricular filling pressure, the central venous pressure (CVP) catheter is ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1977-05-01 00:00:00
abstract：OBJECTIVE:To identify social, behavioral and epidemiologic factors associated with HIV infection among HIV-infected and HIV-uninfected black women residing in North Carolina. DESIGN:A case-control study conducted in August 2004 in North Carolina. METHODS:Cases were 18-40-year-old women with HIV infections diagnosed f...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：CONTEXT:The incidence of esophageal adenocarcinoma is rising and has surpassed squamous cell carcinoma. OBJECTIVE:To determine how the increasing incidence of esophageal adenocarcinoma alters the classic clinical presentation and the implications of these changes for diagnosis. DESIGN AND SETTING:A five-year retrospe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND AND STUDY AIMS:Barrett's Esophagus (BE) is a well-recognized pre-malignant condition. Previous data indicate histologically confirmed BE frequency varies by ethnicity in the United States. However, clinical factor assessment to explain this has only occurred in a veteran population to date. The study aim was...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.09.008
更新日期：2019-04-01 00:00:00
abstract：:Magnetic resonance spectroscopy (MRS) provides a means to assess functional (metabolic activity) of the brain. It is now possible to perform MRS in a clinical setting with the use of an inexpensive software package called Proton Brain Exam/Single Voxel (PROBE/SV) developed by General Electric Medical System for use on...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：OBJECTIVES:To examine the sexually transmitted infection (STI) and HIV testing practices of primary care providers (PCPs) practicing in predominantly Hispanic communities. METHODS:This is a cross-sectional study. PCPs were identified by matching ZIP codes of physician directories with ZIP codes of Los Angeles County a...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:Particularly for children of color, one's productivity and prosperity as an adult depend to a significant degree on one's education as a child. Education is both the attainment of skills and the development of character. In the National Academy of Science's 1993 publication, Losing Generations: Adolescents in High Ris...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-07-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to characterize African-American women attending a community clinic who report frequent douching (douching > or = 2 times per week). METHODS:A consecutive sample of 115 black women attending a community clinic were interviewed face-to-face about their douching practices. Logistic...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:Our study aims to build on existing literature by assessing factors that may be associated with an increased risk of burnout amongst medical students, particularly students of color. METHODS:Our cross-sectional survey included the Copenhagen Burnout Inventory (CBI) and additional de novo questions. Surveys wer...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2020.05.019
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:To assess the level and determinants of African-American physicians' employment in health maintenance organizations (HMOs), particularly early in their careers. METHODS:We analyzed data from the 1991 and 1996 Young Physicians Surveys to assess racial differences in the likelihood of HMO employment (n = 3,70...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:Growth data were analyzed on 406 infants (211 black, 195 white) during their first two years of life. Only term children weighing more than 2500 g were included in the study. Prenatal and postnatal care were provided at the same university affiliated health maintenance organization. Mean birth weight of black female n...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:An update of the state of the art of cancer chemotherapeutic treatment of genitourinary tract cancer is described in this multi-part series. Included in the review are cancers of the kidney, bladder, prostate, testicle, ovary, uterus, vulva, and gestational trophoblastic neoplasms. Part 2 focuses on Wilms' tumor and b...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1988-02-01 00:00:00
abstract：PURPOSE:The purpose of this qualitative study was to explore the causes and management of blindness and blinding eye conditions as perceived by rural dwellers of two Yoruba communities in Oyo State, Nigeria. METHODS:Four focus group discussions were conducted among residents of Iddo and Isale Oyo, two rural Yoruba com...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:The surgical approach to liver injury depends on a clear and concise characterization of the wound. Blunt trauma can produce devastating wounds that disrupt hepatic venous drainage. Atrial caval shunting remains a useful technique for Grade V liver wounds. Liver packing may be necessary if diffuse lobar injury, acidos...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：ISSUES:Tobacco Control remains one of the greatest determinants for reducing the morbidity and mortality of African Americans. OBJECTIVE:To examine the scope and consequences of tobacco use among African Americans and characterize its implications for the National Medical Association physician membership and their pat...
journal_title：Journal of the National Medical Association
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2002-02-01 00:00:00
abstract：:Labetalol and hydrochlorothiazide (HCTZ) were compared for their efficacy in controlling hypertension of blacks in a prospective, double-blind study. Sixty-one adult patients with mild to moderate hypertension (standing diastolic blood pressure greater than or equal to 95 mm Hg and less than or equal to 114 mm Hg) wer...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-10-01 00:00:00
abstract：:Bellevue Hospital, the oldest public hospital in the United States and a lineal descendant of an infirmary for slaves, accepted its first African-American resident, Dr. Ubert Conrad Vincent, in 1918. This occurred at a time when many medical centers were not accepting African-American residents. At the end of WWII, on...
journal_title：Journal of the National Medical Association
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:Newly diagnosed insulin-dependent diabetic Nigerian Africans were studied prospectively over a 6-year period and were analyzed for sex, age at diagnosis, and month of onset of symptoms. Insulin-dependent diabetes mellitus (IDDM) rarely occurred in patients younger than the age of 10. A female preponderance occurred in...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:Underrepresented minorities (URMs) make up a disproportionately small percentage of medical school applicants, matriculants, and physicians relative to the general US population. Preprofessional pipeline programs may help introduce URMs to careers in the medical field. MiniMeds was developed as a paracurricular enrich...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30437-5
更新日期：2011-09-01 00:00:00
abstract：:THIS RESEARCH EXAMINES THE KINDS OF PROBLEMS THESE YOUNG FATHERS ARE LIKELY TO SEEK HELP FOR AND ADDRESSES ITSELF TO THE QUESTION: Is there a difference in the help-seeking behavior of unwed adolescent fathers who reside in different cities? Despite the complexity and diversity of their difficulties, it was clear from...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：:This article examines the validity of the National Institute of Mental Health Diagnostic Interview Schedule (DIS) relative to three of its measures: alcoholism, depression, and schizophrenia when compared with the clinical interview. Preliminary results indicate that greater diagnostic agreement was observed for alcoh...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-07-01 00:00:00
abstract：:Small-bowel obstruction due to foreign bodies is unusual in adults. Intestinal obstruction is occasionally caused by pits, bezoars, endoscopy capsules, and gastrostomy tube buttons. We report a rare case of distal small-bowel obstruction due to dental impression material. Avoidance of this potentially life-threatening...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31143-3
更新日期：2009-12-01 00:00:00
abstract：:Carcinoma of the colorectum should be suspected and diagnosed early and treated adequately. Principles of surgical therapy are discussed. Meticulous follow-up is essential and re-exploration to remove recurrent disease is necessary. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
