Abstract：
CONTEXT:The incidence of esophageal adenocarcinoma is rising and has surpassed squamous cell carcinoma. OBJECTIVE:To determine how the increasing incidence of esophageal adenocarcinoma alters the classic clinical presentation and the implications of these changes for diagnosis. DESIGN AND SETTING:A five-year retrospective review (1991-1996) was made. PARTICIPANTS:All patients were identified by a computerized registry search with a diagnosis of esophageal carcinoma. MAIN OUTCOME MEASURES:Clinical presentation; duration of symptoms; and correlation with diagnosis, pathology, treatment and outcome. RESULTS:One-hundred-eight (35%) patients had squamous cell carcinoma and 199 (65%) had adenocarcinoma. Dysphagia and weight loss were more common among patients with squamous cell carcinoma (93% and 68%), when compared to adenocarcinoma (79% and 53%). Twenty-one percent of adenocarcinoma patients had other symptoms presentation, including gastroesophageal reflux disease. Once dysphagia was present, there was no correlation between the duration.of symptoms and survival. However, cancers detected in patients who presented with reflux symptoms without dysphagia showed an improved prognosis over patients who presented with both. CONCLUSIONS:Esophageal adenocarcinoma has surpassed squamous cell carcinoma. Gastroesophageal reflux was associated with an earlier stage of presentation compared to the "classic" presentation of esophageal cancer.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Gibbs JF,Rajput A,Chadha KS,Douglas WG,Hill H,Nwogu C,Nava HR,Sabel MSsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
620-6issue
6eissn
0027-9684issn
1943-4693journal_volume
99pub_type
杂志文章abstract：:This study investigates parameters related to calcium and bone metabolism by determining the concentrations of total calcium, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, parathyroid hormone, and phosphorous in young pregnant women. The patient population was 30 pregnant Nigerian teenage women grouped by trimester (1...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:The author presents a four-year follow-up of a male patient with cancer of the breast. The lesion was large, fungating, and ulcerating. It was treated effectively with cobalt without mastectomy. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1987-08-01 00:00:00
abstract：PURPOSE:To report a case of a patient with mixed mechanism glaucoma and a clear lens who was successfully surgically treated with combination cataract extraction, goniosynechiolysis and the Hydrus stent. OBSERVATION:A 59-year-old Afro-Latino woman with a history of mixed mechanism glaucoma. She was taking latanoprost ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2020.04.003
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVES:African Americans bear a disproportionate burden of lower extremity complications associated with a type 2 diabetes diagnosis. We examined the relationship that self-reported foot care knowledge, foot self-care behaviors, and foot self-care management barriers had on a participants' intention to maintain lon...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.10.004
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND/PURPOSE:With the urgency to create more equitable health care, increased research and early exposure to health interventions and clinical medicine are imperative. Health disparities continue to persist nationwide, particularly in underserved areas and among traditionally disadvantaged populations. In additio...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.12.003
更新日期：2020-02-01 00:00:00
abstract：:Precocious puberty can be very confusing and frightening to an affected child and his or her family. The following presentation includes the pertinent physiology, psychology, etiology, diagnosis, and treatment of precocious pubertal development. Radioimmunoassays for gonadotropins and several key hormones are now avai...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1979-02-01 00:00:00
abstract：:This paper describes the use of a mobile health unit as a part of a community education, screening, and counseling program. By virtue of its mobility and more flexible hours, this model extends services into the basic urban, suburban, and rural community. Quality control of the diagnostic and counseling activities on ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-10-01 00:00:00
abstract：:Students of African ancestry often share an experience of being a racialized minority in the context of the educational institution. Late Professor of Anthropology John Ogbu's Cultural-ecological Theory of Academic Disengagement is employed to describe the negative responses encountered by peers in the name of academi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2016.12.001
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To study racial disparities and the weapons used to commit youth homicide in New Jersey. METHODS:The homicide data were obtained from New Jersey death certificate files, 1989-1997. RESULTS:There was a statistically significant racial disparity in homicide incidence rates in this study. The homicide incidenc...
journal_title：Journal of the National Medical Association
pub_type： 社论
doi：
更新日期：2004-04-01 00:00:00
abstract：:This preliminary study explored the roles of knowledge, attitudes, and significant others on decisions of older African-American women to enroll in a clinical trial involving estrogen and osteoporosis. Sixteen older African-American women (average age 75 years) participated in three focus groups. Twelve of the women h...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：:Over 600 Howard University medical alumni of seven representative classes graduating from 1955 to 1975 were surveyed by questionnaire in 1975 and 1976. Replies of the 252 black respondents confirm that these graduates are providing substantial care to blacks, the economically disadvantaged, and residents of the inner ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-02-01 00:00:00
abstract：:A 75-year-old woman with two previous neck operations for follicular carcinoma of the thyroid presented with a breast mass nine years after diagnosis. The mass recurred one month after excisional biopsy. Pathological examination revealed metastatic follicular carcinoma. The breast tumor was weakly positive for estroge...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-11-01 00:00:00
abstract：:The epidemiology of nosocomial infections was studied for 5 years in 10 Oklahoma hospitals. These were categorized into small and large hospitals. The seven small hospitals averaged 47 beds and the three large hospitals averaged 266 beds. Overall, most of the infected patients were < 5 years of > 60 years of age. Fema...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：PURPOSE:To explore why some African-American smokers choose not to use nicotine replacement therapy (NRT) when attempting smoking cessation. DESIGN AND SETTING:Semistructured audiotaped qualitative telephone interviews. PARTICIPANTS:Thirty-three participants who were enrolled in a five-week cessation program were off...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31211-6
更新日期：2008-02-01 00:00:00
abstract：:Decreased revenue from clinical services has required academic hospitals and physicians to improve productivity. Medical student education may be a significant hindrance to increased productivity and income. This study quantifies the amount of time spent by faculty members teaching medical students in an ambulatory ne...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
abstract：:A questionnaire was administered to 52 females with sickle disease of genotypes Hgb SS, SC, and S-thalassemia, and to 80 control subjects. They answered questions pertaining to their contraceptive habits, their reproductive habits, and their sexual activity. It was found that sexual activity differed significantly f...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:A review of 313 intraoperative consultations and/or frozen section evaluations of neoplasms of the ovary was conducted. The intraoperative diagnosis of benign or malignant was compared with the diagnosis found at permanent section. Only six cases were deferred to permanent section. The overall accuracy was 93.9%. The ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:There has been considerable discussion about translating science into practical messages, especially among urban minority and "hard-to-reach" populations. Unfortunately, many research findings rarely make it back in useful format to the general public. Few innovative techniques have been established that provide resea...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:Peritoneal lavage fluid for cytologic study was obtained in 73 patients undergoing primary surgery for stage I endometrial adenocarcinoma. Preoperative irradiation was not used. Malignant cells consistent with endometrial adenocarcinoma were present in eight (11 percent) cases. There was no significant difference in t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1985-10-01 00:00:00
abstract：UNLABELLED:Severe hyponatremia is associated with increased morbidity and mortality. Clinicians treating patients with severe hyponatremia are often torn between a desire to promptly raise serum sodium concentration to a "safe range," and at the same time, to avoid excessively rapid correction of hyponatremia. The aim ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:The data of the Third National Cancer Survey show for many cancer types, large differences in cancer incidence between Euro-Americans and Afro-Americans.(1) As in other racial studies, it is difficult to separate environmental and genetic factors. For the cancers which are more frequent among Afro-Americans, environme...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1981-08-01 00:00:00
abstract：:This survey was undertaken to determine the prevalence of diabetes mellitus and impaired glucose tolerance in a group of urban adults in Ibadan, Nigeria. A total of 998 subjects randomly selected from five main ministries and departments in the Government Secretariat participated in the survey. Each subject was asked ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Newly diagnosed insulin-dependent diabetic Nigerian Africans were studied prospectively over a 6-year period and were analyzed for sex, age at diagnosis, and month of onset of symptoms. Insulin-dependent diabetes mellitus (IDDM) rarely occurred in patients younger than the age of 10. A female preponderance occurred in...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:Stroke in black Americans is an important health problem that has been understudied. A brief review of the pertinent literature and strategies for evaluating and managing patients with cerebrovascular disease are presented. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:A day-long seminar was held at Wake Forest University School of Medicine to address barriers among ethnic minorities in cancer clinical trials and explore ways that individuals who design and conduct clinical trials could increase minority representation. Speakers addressed implications of under-representation of mino...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2002-01-01 00:00:00
abstract：:Bellevue Hospital, the oldest public hospital in the United States and a lineal descendant of an infirmary for slaves, accepted its first African-American resident, Dr. Ubert Conrad Vincent, in 1918. This occurred at a time when many medical centers were not accepting African-American residents. At the end of WWII, on...
journal_title：Journal of the National Medical Association
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:The rare association of protease inhibitor deficiency (Pi(zz) genotype) in a black American with chronic, obstructive pulmonary disease due to asthmatic bronchitis, rather than basal pan lobular emphysema, is presented. The late onset of symptoms, despite environmental exposures, is also unusual in this homozygote, as...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：PURPOSE OF THE STUDY:To review technological advances in the field of radiation oncology in the management of benign and malignant diseases. BASIC PROCEDURES:We reviewed major advances in the field of radiation oncology in the past decade with special emphasis on reduction of treatment related toxicities, and technolo...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：:A higher incidence of hallucinations has been previously reported among blacks, as compared to whites, in both psychiatric and nonpsychiatric populations. In contrast to these reports, which relied on hospital records, the present study utilized standardized research rating scales, and confirmed the above observation ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1981-06-01 00:00:00
abstract：:A retrospective descriptive study of older patients evaluated by the psychiatric emergency service (PES) of a general hospital was implemented. The medical records of all patients aged 65 years and older evaluated by the PES during the 1980 calendar year were reviewed. Seventy-four patients were identified, 38 male an...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
