Abstract：
BACKGROUND:Dental caries is a big public health problem which is prevalent in the highest degree worldwide, especially in lower socioeconomic levels. This study aims to investigate the anti-caries effects of Curcumin in Turmeric on the caries model of enamel under laboratory conditions. METHODS:In order to make a reliable model of caries, a Streptococcus mutans (ATCC 3568) bacterium was used. The biofilm was created on enamel slabs in 5 days. There were 5 groups of slabs. In order to create Cariogenic conditions, the slabs were exposed to Sucrose 10% three times a day and then, it was exposed to different concentrations of Curcumin (5, 10, 20 mg/ml). The slabs of one group were exposed to the normal saline after the exposure to Sucrose and called positive caries control group; and the other group was exposed to normal saline in each time of exposure which was called negative caries control groups. Environment PH was measured by PH meter two times in a day. After the laboratory phase, the slabs were washed and dried and Vickers hardness test was used to determine the superficial hardness and then the decrease rate of superficial hardness (SHL%) was measured by the approved formula. SPSS version 20 was used to analyse the data. Then, to analyse the data, One-way ANOVA with 95% confidence, Kolmogorov - Smirnov, and Tukey test was used. RESULTS:The present study showed that Curcumin can have anti caries effect at the most level even in the least level of concentration used in this study (5 mg/ml). With regard to changes in PH of environment, we can declare that Curcumin results in reducing the dental caries by restraining the bacterial activity. CONCLUSIONS:Regarding that these results were received in laboratory conditions, further studies are needed.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Basir L,Kalhori S,Zare Javid A,Khaneh Masjedi Mdoi
10.1016/j.jnma.2017.12.005subject
Has Abstractpub_date
2018-10-01 00:00:00pages
486-490issue
5eissn
0027-9684issn
1943-4693pii
S0027-9684(17)30174-8journal_volume
110pub_type
杂志文章abstract：:Stroke in black Americans is an important health problem that has been understudied. A brief review of the pertinent literature and strategies for evaluating and managing patients with cerebrovascular disease are presented. ...
journal_title：Journal of the National Medical Association
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abstract：:In 1977, the National Institute of Mental Health funded the National Survey of Black Americans (NSBA). The NSBA was an omnibus, nationally representative sample (N = 2,107) of adult black Americans that explored numerous issues relevant to black quality of life. One topic that has received much attention is where blac...
journal_title：Journal of the National Medical Association
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journal_title：Journal of the National Medical Association
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journal_title：Journal of the National Medical Association
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doi：
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journal_title：Journal of the National Medical Association
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journal_title：Journal of the National Medical Association
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journal_title：Journal of the National Medical Association
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journal_title：Journal of the National Medical Association
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