Abstract：
:The distribution of gap junctions (nexuses) in various parts of the small and large intestines of the guinea-pig was studied using the freeze-fracture technique and in thin sections. The percentage area of smooth muscle cell surface occupied by gap junctions varies from 0.50% in the circular muscle of the duodenum to zero in the longitudinal muscle of the ileum. In the circular muscle of the jejunum and ileum the area occupied by nexuses is 0.22% (or about 11 micrometers 2 per cell). The sizes of junctions range from less than 0.01 micrometer 2 to 0.20 micrometer 2, with two-thirds of them being smaller than 0.05 micrometer 2. In the colon, gap junctions are rare, very small and confined to the circular muscle layer. Even the smallest aggregates of intramembrane particles correspond to areas of close apposition between the membranes of adjacent cells; it is therefore justified to interpret them as being gap junctions. Some gap junctions are formed between a smooth muscle cell and an interstitial cell. Gap junctions are not found in the longitudinal muscle of the small intestine; this is in sharp contrast to the abundance of gap junctions in the adjacent circular layer. In the small intestine of cats and rabbits, gap junctions are abundant in the circular muscle layer, whereas they are very small in size and very few in number in the longitudinal muscle layer.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Gabella G,Blundell Ddoi
10.1007/BF00209987subject
Has Abstractpub_date
1981-01-01 00:00:00pages
469-88issue
3eissn
0302-766Xissn
1432-0878journal_volume
219pub_type
杂志文章abstract：:The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000240
更新日期：2000-08-01 00:00:00
abstract：:Rat thymic phagocytic cells were characterized in vitro using various light- and electron-microscopical techniques. Thymic cell suspensions were mechanically prepared and enriched for non-lymphoid cells, which were predominantly phagocytic and of three types. Type I showed acid phosphatase (APh) activity in small gran...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222183
更新日期：1983-01-01 00:00:00
abstract：:Peeling skin syndrome is a heterogeneous group of rare disorders. Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads (PLACK syndrome, OMIM616295) is a newly described form of PSS with an autosomal recessive mode of inheritance. We report a 5.5-year-old boy with features of PLACK syndrome. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03077-9
更新日期：2019-11-01 00:00:00
abstract：:Captopril [1-(D-3-mercapto-2-methyl-1-oxopropyl)-L-proline (S,S)] is now known to be an inhibitor of angiotensin-converting enzyme. In male mice, the juxtaglomerular cells were examined by electron microscopy 42 h after administration of captopril. Numerous dense granules appeared in the rough endoplasmic reticulum of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209980
更新日期：1981-01-01 00:00:00
abstract：:It is believed that differentiation and maintenance of taste buds in vertebrates is dependent on the trophic function of their sensory nerve supply. In the present work, colchicine was injected into the circumvallate papilla of the rat. This produced a reversible blockade of neuroplasmic transport and disappearance of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231023
更新日期：1978-08-25 00:00:00
abstract：:To investigate the control of the timing in the epithelio-mesenchymal transformation of the neural crest into a migrating population, neural anlagen (neural tube plus crest) were isolated from 2-day quail embryos by proteases in the presence of CA++ and explanted onto substrates favourable for neural crest cell migrat...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218011
更新日期：1985-01-01 00:00:00
abstract：:The uptake of macromolecules and larger energy-rich particles into the cell is known as phagocytosis. Phagocytosed material is enzymatically degraded in membrane-bound vesicles of the endosome/lysosome system (intracellular digestion). Whereas most, if not all, cells of the animal body are equipped with the molecular ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-019-03096-6
更新日期：2019-09-01 00:00:00
abstract：:Pancreatic acinar cells of euthermic, hibernating and arousing individuals of the hazel dormouse Muscardinus avellanarius (Gliridae) have been observed at the electron-microscopic level and analysed by means of ultrastructural morphometry and immunocytochemistry in order to investigate possible fine structural changes...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051082
更新日期：1998-06-01 00:00:00
abstract：:The spermatogonial stem cell line in prepubertal and adult bovine testis was studied by electron microscopy and protein gene product 9.5 immunohistochemistry. Three successive spermatogonia precursor cell configurations were observed. Small basal stem cells were found to possess a spherical shape and nuclei with two t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00583394
更新日期：1995-08-01 00:00:00
abstract：:The dissociation and maintenance in culture of cells derived from the mushroom bodies of adult crickets (Acheta domesticus) are described. This primary culture was developed in order to investigate maturation and differentiation of mushroom-body cells including Kenyon cells, the major intrinsic interneurons of mushroo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051023
更新日期：1998-03-01 00:00:00
abstract：:The periodontal ligament (PDL) is a highly specialized tissue connecting the cementum with the tooth socket bone and affects the life span of the tooth. However, little is known about the precise characteristics and regenerative mechanism of PDL cells because of the absence of specific markers and cell lines. Therefor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0101-4
更新日期：2006-04-01 00:00:00
abstract：:To identify and describe ovarian follicles committed to undergo follicular degeneration (atresia), immature rats were primed with pregnant mare serum gonadotropin (PMSG). After PMSG treatment, preovulatory follicles develop but subsequently degenerate. Prior to the appearance of pyknotic nuclei (Stage I of atresia), d...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233727
更新日期：1980-01-01 00:00:00
abstract：:CD4+CD25+(high) regulatory T cells (Tregs) play a pivotal role in the control of the immune response. A growing body of evidence suggests the reduced function of these cells in autoimmune diseases, including type 1 diabetes (T1D). Restoration of their function can potentially delay further disease development. In the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0900-0
更新日期：2010-03-01 00:00:00
abstract：:In mouse hepatocytes, the gap junctional proteins connexin32 (Cx32) and connexin26 (Cx26) are expressed in the same gap junctional plaque. Expression of the major Cx32 protein is downregulated during liver regeneration and cholestasis. Here we have analyzed the acute-phase response (after experimental inflammation) an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000177
更新日期：2000-04-01 00:00:00
abstract：:Intercellular communication between smooth muscle cells is crucial for contractile behaviour in normal and pathologically altered urinary bladder. Since the study of coupling is difficult in situ, we established cell cultures of bladder smooth muscle cells to analyse coupling mechanisms. Microinjection of Lucifer yell...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0559-2
更新日期：2002-08-01 00:00:00
abstract：:The innervation of the anococcygeus muscle of the rat was investigated with regard to the histochemical features of nerve fibers within the muscle and to the location of the postganglionic autonomic neurons which are the source of these fibers. Acetylcholinesterase-positive fibers and catecholaminergic fibers are abun...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00571438
更新日期：1990-01-01 00:00:00
abstract：:Regenerated adrenocortical nodules were obtained by implanting fragments of the capsular tissue of excised adrenal glands into the musculus gracilis of rats (Belloni et al. 1990). Five months after the operation, operated rats showed a normal basal blood level of corticosterone, but a very low concentration of circula...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318136
更新日期：1991-07-01 00:00:00
abstract：:The effects of radiotherapy on neuropeptide expression in the rat larynx were studied. Irradiation was given for five days, 6 or 8 Gray daily. Ten days after the end of irradiation, the larynx, the laryngeal nerves and different ganglia related to the larynx were dissected out from irradiated and control animals and p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00300691
更新日期：1995-01-01 00:00:00
abstract：:Neurotrophins NGF, BDNF, NT-3, and NT-4/5 are members of the neurotrophin family of proteins, which support the survival and induce differentiation of vertebrate neurons. We have studied the effects of neurotrophins on growth cones of embryonic sensory neurons. BDNF and NT-4/5 cause growth cone collapse and transient ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050933
更新日期：1997-11-01 00:00:00
abstract：:Adult white-footed mice, Peromyscus leucopus, were kept either in long photoperiod (LP; LD 16:8) or in short photoperiod (SP; LD 8:16) for six weeks. Ovaries were serially sectioned and examined histologically. Preantral follicles were observed to release their oocyte into the ovarian stroma. This phenomenon is termed...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218373
更新日期：1982-01-01 00:00:00
abstract：:NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051246
更新日期：1999-03-01 00:00:00
abstract：:Unique rod-shaped secretory granules were observed among oval or spherical secretory granules in GH cells of the anterior pituitary gland of musk shrew using the protein A-gold procedure combined with electron microscopy. The rod-shaped and spherical secretory granules were both immunoreactive by the immuno-gold metho...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215454
更新日期：1988-01-01 00:00:00
abstract：:In the small intestine of the pig, neuromedin U (NMU)-immunoreactivity was mainly confined to the nerve plexus of the inner submucosal and mucosal regions. After colchicine treatment, a high number of immunoreactive nerve cell bodies was observed in the plexus submucosus internus (Meissner), whereas only a low number ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00239453
更新日期：1989-11-01 00:00:00
abstract：:The structure of the bulbus arteriosus of a wide range of teleost fish is described with particular reference to the vascularization and innervation. The adventitia of the organ consists of blood vessels and large nerve bundles in a collagen matrix. The nerve bundles contain monoamines, and fluorescence studies show s...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00240106
更新日期：1979-02-15 00:00:00
abstract：:The distribution of estradiol-concentrating cells in the pituitary of the platyfish, Xiphophorus maculatus, is studied after the injection of 3H estradiol-17 beta by thaw-mount autoradiography. Autoradiograms prepared 2-8 h after the injection show nuclear concentration of radioactivity in certain cells of the rostral...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234188
更新日期：1979-05-25 00:00:00
abstract：:We have recently reported that Sox2-expressing pituitary stem/progenitor cells contact each other via a tight-junction protein CAR to form stem/progenitor cell niches in the marginal cell layer facing the lumen and in the clusters scattered in the parenchyma of the anterior lobe. However, the microenvironment of the n...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-2054-y
更新日期：2015-03-01 00:00:00
abstract：:An ectodermal network of nerve cells has been observed in the echinopluteus. It seems to connect the ectodermal cell bodies with each other and with deeper parts of the nerve system. Together with the neurohumour containing parts of the ventral and oral ciliated bands, the nerve cells probably provide the larva with t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219793
更新日期：1977-04-07 00:00:00
abstract：:Loss of serotonergic and dopaminergic neurons may have serious implications for normal brain function. Drosophila models of neurodegenerative diseases utilize the short life-span and simple anatomy of the fly to characterize the molecular and genetic processes characteristic of each dysfunctional state. In fly embryon...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0940-4
更新日期：2004-09-01 00:00:00
abstract：:The electrocyte fibers in the gymnotid Sternarchus albifrons are highly differentiated myelinated axons which exhibit several types of nodes of Ranvier and characteristically short internode lengths. In the present study, regeneration of the electrocyte fibers following removal of the tail was examined by electron mic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233869
更新日期：1980-01-01 00:00:00
abstract：:Galanin immunoreactivity was observed in nerve cell bodies and nerve fibres, but not in enteroendocrine cells, in the small intestine of the guinea-pig. Nerve terminals were found in the myenteric plexus, in the circular muscle, in submucous ganglia, around submucous arterioles, and in the mucosa. Lesion studies showe...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218954
更新日期：1987-12-01 00:00:00
