Dipsogenic effect of L-5-hydroxytryptophan in rats.

abstract：:Individual cardiac nerves from which stimulation elicited cardioinhibition (bradycardia and negative inotropism) were identified in 24 of 38 dogs. Subsequently, 3-25 microliters of 30% horseradish peroxidase (HRP) were injected into an identified cardiac nerve. After a 3-day survival period, the medulla oblongata was ...

journal_title：Brain research bulletin

authors： Hopkins DA,Armour JA

更新日期：1982-04-01 00:00:00

abstract：:Ten years after the discovery of human diseases caused by trinucleotide repeat expansions, searching for mechanistic links between gene mutation and pathological phenotype remains a fundamental and unsolved issue. Evidence accumulated so far indicates that the pathogenesis of repeat disorders is complex and multi-fact...

journal_title：Brain research bulletin

authors： Galvão R,Mendes-Soares L,Câmara J,Jaco I,Carmo-Fonseca M

更新日期：2001-10-01 00:00:00

abstract：:Gestational exposure to nicotine has been shown to interfere with biochemical markers of development of central and peripheral noradrenergic activity. The current study examines the development and function of cardiac beta-adrenergic receptors in the offspring of pregnant rats given nicotine infusions of 6 mg/kg/day f...

journal_title：Brain research bulletin

authors： Navarro HA,Mills E,Seidler FJ,Baker FE,Lappi SE,Tayyeb MI,Spencer JR,Slotkin TA

更新日期：1990-08-01 00:00:00

abstract：:Effects of the selective alpha 2-adrenoceptor agonist, medetomidine, on a compound volley of a tibial nerve stimulation-evoked spinal reflex, pain-induced phrenic motor responses and on postoperative neuropathic pain behavior were studied in rats. Medetomidine (0.3 mg/kg) decreased the amplitude of the compound volley...

journal_title：Brain research bulletin

authors： Taira T,Tanila H,Jyväsjärvi E,Pertovaara A,Kauppila T

更新日期：1995-01-01 00:00:00

abstract：:High dietary salt intake activates the brain renin-angiotensin system in spontaneously hypertensive rats (SHR) and Dahl S rats, resulting in sympathetic hyperactivity and hypertension. Increases of sodium concentration in cerebrospinal fluid (CSF) and/or enhanced responses to CSF sodium are considered to be involved i...

journal_title：Brain research bulletin

authors： Kubo T,Hagiwara Y

更新日期：2006-01-30 00:00:00

abstract：:Adenoviral vector directed gene transfer to rat facial motoneurons occurs efficiently following intra-parenchymal injection of relatively high dosages (> or =10(7) pfu per injection) of a prototype first generation adenoviral vector. However, high level of transgene expression, as observed during the first week follow...

journal_title：Brain research bulletin

authors： Hermens WT,Verhaagen J

更新日期：1998-09-15 00:00:00

abstract：:Methoxetamine (MXE) is a novel psychoactive compound (NPS) that emerged in 2010 as a substitute for the dissociative anaesthetic ketamine. MXE has a reputation of carrying a lower risk of harm than ketamine, however a number of deaths have been reported. Currently very little is known about the psychopharmacological e...

journal_title：Brain research bulletin

authors： Horsley RR,Lhotkova E,Hajkova K,Jurasek B,Kuchar M,Palenicek T

更新日期：2016-09-01 00:00:00

abstract：:Previously we have shown that systemic injection of adenosine antagonists can significantly improve cold tolerance in both rats and humans. However, it is not clear whether systemic administration of adenosine antagonist acts peripherally or centrally at the thermoregulatory site. To resolve this, theophylline (nonsel...

journal_title：Brain research bulletin

authors： Wang XL,Lee TF,Wang LC

更新日期：1990-03-01 00:00:00

abstract：:The effects of a low protein diet during gestation, lactation, and after weaning on the anatomical development of a subcortical nucleate formation, the neostriatum, and a reticulate formation, the diagonal band of Broca, were studied. At 10, 30, and 90 days the volume of the neostriatum was decreased in the experiment...

journal_title：Brain research bulletin

authors： Kemper TL,Pasquier DA,Drazen S

更新日期：1978-09-01 00:00:00

abstract：:The localization and relative number of serotonergic (5HT) cell bodies in the brainstem of the cat were studied through the use of a specific immunocytochemical technique. A surprisingly large number of 5HT cells were found in regions in addition to the classical raphe nuclei (obscurus, pallidus, magnus, centralis sup...

journal_title：Brain research bulletin

authors： Jacobs BL,Gannon PJ,Azmitia EC

更新日期：1984-07-01 00:00:00

abstract：:Neural progenitors in the subgranular zone of the hippocampal formation form a continuously proliferating cell population, generating new granule neurons throughout adult life. Between 10 days and 1 month after their formation, many of the newly generated cells die. The present study investigated whether a partial les...

journal_title：Brain research bulletin

authors： Van der Borght K,Mulder J,Keijser JN,Eggen BJ,Luiten PG,Van der Zee EA

更新日期：2005-09-30 00:00:00

abstract：:We studied the ontogeny of muscarinic depression in the developing rat visual cortex using carbachol (a nonhydrolyzable cholinergic agonist) application to neocortical slices obtained from four postnatal age groups: 9-10 days, 15 days, 30-40 days and 18 months. Carbachol suppressed the evoked synaptic response of laye...

journal_title：Brain research bulletin

authors： Vaknin G,Teyler TJ

更新日期：1991-02-01 00:00:00

abstract：:Microinjection of galanin into the paraventricular nucleus (PVN) of the hypothalamus has been reported to predominantly increase dietary fat consumption during the light or late dark periods. However, there have been no studies of the macronutrient-specific effects of galanin administered into the amygdala (AMY). We u...

journal_title：Brain research bulletin

authors： Smith BK,York DA,Bray GA

更新日期：1996-01-01 00:00:00

abstract：:Acute inflammation activates macrophages or monocytes and subsequently releases several inflammatory cytokines and reactive oxygen and nitrogen species. These proinflammatory cytokines activate astrocytes and trigger neurodegenerative diseases. In this work, we chose to address the mechanistic aspects of alpha-crystal...

journal_title：Brain research bulletin

authors： Masilamoni JG,Vignesh S,Kirubagaran R,Jesudason EP,Jayakumar R

更新日期：2005-10-15 00:00:00

abstract：:Male and female rats were treated daily for 7 days with mazindol (5, 10, and 20 mg/kg), an anorectic drug, and tested in the open field. Mazindol developed sensitization to its locomotor stimulatory effect in both sexes on day 7 with a nondose-dependent pattern of response. However, the locomotor activity appeared to ...

journal_title：Brain research bulletin

authors： Zanin M,Takahashi RN

更新日期：1994-01-01 00:00:00

abstract：:The distribution of substance P-containing fibers in the cerebral cortex and the hippocampal formation of the Japanese monkey (Macaca fuscata fuscata) was studied by immunohistochemistry using a monoclonal antibody raised against substance P. The results were compared with the distribution in homologous regions of the...

journal_title：Brain research bulletin

authors： Iritani S,Fujii M,Satoh K

更新日期：1989-02-01 00:00:00

abstract：:The influence of gender and stage of the estrous cycle on the levels of acetylcholine, serotonin, and noradrenaline in the hippocampus and on the susceptibility of the cholinergic septo-hippocampal pathway to the neurotoxic effect of ethylcholine aziridinium (AF64A) was investigated in the rat. Levels of acetylcholine...

journal_title：Brain research bulletin

authors： Hörtnagl H,Hansen L,Kindel G,Schneider B,el Tamer A,Hanin I

更新日期：1993-01-01 00:00:00

abstract：:The present study investigated whether the raphe neurons which give rise to the transient serotonergic fibers in the visual cortex of neonatal rats persist or disappear as the rats mature. Three experiments were performed employing the WGA-apoHRP-Au retrograde transport technique in conjunction with 5-HT or WGA-HRP im...

journal_title：Brain research bulletin

authors： Koh T,Nakazawa M,Kani K,Maeda T

更新日期：1991-11-01 00:00:00

abstract：:The topographical distribution of cholinergic cell bodies has been studied in the rat brain and spinal cord by choline acetyltransferase (ChAT)-immunohistochemistry and acetylcholinesterase (AChE)-pharmacohistochemistry using diisopropylfluorophosphate (DFP). The ChAT-containing cells and the cells that stained intens...

journal_title：Brain research bulletin

authors： Satoh K,Armstrong DM,Fibiger HC

更新日期：1983-12-01 00:00:00

abstract：:Recent investigations of the nucleus ambiguus (NA) have attempted to identify motoneurons associated with the branchiomeric muscles of the larynx and pharynx. However, relatively little attention has been directed to the levator veli palatini muscle (LVP) which is critical in respiration, deglutition and eustachian tu...

journal_title：Brain research bulletin

authors： van Loveren H,Saunders MC,Keller JT

更新日期：1983-09-01 00:00:00

abstract：:The non-adenosine nucleoside guanosine (Guo) was demonstrated to decrease quinolinic acid(QA)-induced seizures, spontaneously emerged absence epileptic seizures and lipopolysaccharide(LPS)-evoked induction of absence epileptic seizures suggesting its antiepileptic potential. It was also described previously that intra...

journal_title：Brain research bulletin

authors： Lakatos RK,Dobolyi Á,Todorov MI,Kékesi KA,Juhász G,Aleksza M,Kovács Z

更新日期：2016-06-01 00:00:00

abstract：:Endogenous opioids (EO) probably do not modulate endotoxin (LPS)- or interleukin 1 (IL1)-induced fever because naloxone does not prevent its development. Yet, increases in CSF and hypothalamic levels of beta-endorphin have been reported during LPS-and IL1-induced fevers. Since IL1 also reduces the specific binding of ...

journal_title：Brain research bulletin

authors： Ahokas RA,Seydoux J,Llanos-Q J,Mashburn TA Jr,Blatteis CM

更新日期：1985-12-01 00:00:00

abstract：:Some C57Bl/6 mice become obese, whereas others remain lean when raised on a high-fat diet. The mechanisms underlying this interindividual susceptibility to diet-induced obesity remain unknown. Because hypothalamus plays a major role in the regulation of body weight, this study was conducted to identify the differences...

journal_title：Brain research bulletin

authors： Xin X,Storlien LH,Huang XF

更新日期：2000-07-01 00:00:00

abstract：:The effects of delta-9-tetrahydrocannabinol (delta-9-THC) on monosynaptic population responses in hippocampal CA1 pyramidal cells were examined in acute rats for several doses and at several post injection time periods. Delta-9-THC enhanced paired pulse inhibition in a dose-dependent manner; however biphasic dose effe...

journal_title：Brain research bulletin

authors： Weisz DJ,Gunnell DL,Teyler TJ,Vardaris RM

更新日期：1982-02-01 00:00:00

abstract：:Electrophysiologic response characteristics of mouse sciatic nerve and spinal cord were investigated following CNS infection with the temperature-sensitive (ts) vesicular stomatitis virus (VSV) mutant G31 KS5. Measurements were obtained before clinical symptoms of the virus-induced CNS disease appeared. Sciatic nerve ...

journal_title：Brain research bulletin

authors： Gerren RA,Johnson TC

更新日期：1994-01-01 00:00:00

abstract：:Fetal ventromedial hypothalamic (VMH) tissue was transplanted into or around the third ventricle of adult Fischer 344 rats to determine if transplanted VMH tissue could reverse the hyperphagia and obesity produced by bilateral VMH electrolytic lesions. Host VMH-lesioned rats received stereotaxic implants of 13 to 19 p...

journal_title：Brain research bulletin

authors： Ono K,Kawamura K,Shimizu N,Ito C,Plata-Salamán CR,Ogawa N,Oomura Y

更新日期：1990-01-01 00:00:00

abstract：:Measurements were made in 29 adult baboons that were housed in social groups, allowing the occurrence of the full range of species-specific behavioral interactions. The cardiovascular variables measured included blood pressure, heart rate, renal blood flow, lower limb blood flow, and occasionally mesenteric blood flow...

journal_title：Brain research bulletin

authors： Smith OA,Astley CA,Spelman FA,Golanov EV,Bowden DM,Chesney MA,Chalyan V

更新日期：2000-09-01 00:00:00

abstract：:Reserpine depletes dopamine (DA) levels and increases tyrosine hydroxylase (TH) activity in the rat corpus striatum. TH is activated not only by enhancement of DA neuronal impulse flow, but also by cessation of impulse flow. To assist in the understanding of the relative contribution of impulse flow to the regulation ...

journal_title：Brain research bulletin

authors： German DC,McMillen BA,Sanghera MK,Saffer SI,Shore PA

更新日期：1981-02-01 00:00:00

abstract：:We previously reported that systemic treatment with a noncompetitive antagonist affecting the NMDA subtype of excitatory amino acid (EAA) receptor, MK-801, inhibits photic induction of Fos-like immunoreactivity (Fos-lir) in the hamster suprachiasmatic nucleus (SCN). Because MK-801 blocks the Ca2+ channel associated wi...

journal_title：Brain research bulletin

authors： Abe H,Rusak B,Robertson HA

更新日期：1992-05-01 00:00:00

abstract：:Astrocytes become activated and proliferate in response to autoimmune diseases involving the CNS. In many cases, elevated numbers of astrocytes may compound inflammatory responses and exacerbate neuronal degeneration. The regulation of astrocytes in disease states has been shown as an important corollary to disease pr...

journal_title：Brain research bulletin

authors： Campbell AM,Zagon IS,McLaughlin PJ

更新日期：2013-01-01 00:00:00