Abstract:
:The localization and relative number of serotonergic (5HT) cell bodies in the brainstem of the cat were studied through the use of a specific immunocytochemical technique. A surprisingly large number of 5HT cells were found in regions in addition to the classical raphe nuclei (obscurus, pallidus, magnus, centralis superior, and dorsalis). Foremost among these were: the ventral medulla, just dorsal to the pyramidal tract and inferior olivary complex, and especially the area in and around the lateral reticular nucleus; the dorsal pons, surrounding the central reticular core, and in the central gray area; and a region in the mesencephalon, in and around the interpeduncular nucleus. The advantages and disadvantages of the existing schemas for subdividing and labeling groups of brain 5HT neurons are discussed.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Jacobs BL,Gannon PJ,Azmitia ECdoi
10.1016/0361-9230(84)90003-0subject
Has Abstractpub_date
1984-07-01 00:00:00pages
1-31issue
1eissn
0361-9230issn
1873-2747pii
0361-9230(84)90003-0journal_volume
13pub_type
杂志文章abstract::The vestibulo-ocular reflex (VOR) has historically been considered a computationally simple reflex: to stabilize images on the retina against imposed head rotation, the eyes must be counterrotated by an equal amount in the opposite direction. During almost any head rotation, however, the eyes are also translated. We s...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(96)00118-9
更新日期:1996-01-01 00:00:00
abstract::A method is described for the removal of discrete areas of the monkey brain. A detailed mapping of norepinephrine, dopamine, choline acetyltransferase and glutamic acid decarboxylase in the newborn and pubescent monkey brain is presented. ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(80)80016-5
更新日期:1980-07-01 00:00:00
abstract::Patterns of female sexual behavior in the hamster are qualitatively different from that observed in the rat. Hamsters demonstrate tonic immobility and a sustained lordotic response that can last for several minutes following minimal stimulation from the male while in rats, the lordotic response is highly dependent upo...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(87)90064-5
更新日期:1987-12-01 00:00:00
abstract::Groups of male Sprague-Dawley rats were predominantly fed either a high-fat or a high-carbohydrate (CHO) diet. For designated 2-day periods, their diets were switched. After baseline measurements of food and water intake, the rats were made diabetic by injections of either 40 or 46-50 mg/kg streptozotocin. Food and wa...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(86)90100-0
更新日期:1986-12-01 00:00:00
abstract::The present study investigated whether the raphe neurons which give rise to the transient serotonergic fibers in the visual cortex of neonatal rats persist or disappear as the rats mature. Three experiments were performed employing the WGA-apoHRP-Au retrograde transport technique in conjunction with 5-HT or WGA-HRP im...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(91)90044-k
更新日期:1991-11-01 00:00:00
abstract::To elucidate the role of the medial basal hypothalamus (MBH) in stress-induced prolactin (Prl) release, adult male rats which had received monosodium glutamate (MSG 4 mg/g) on alternate days for the first 10 days of life were subjected to ether stress for 2 min. Blood samples were drawn at 0, 15, 30 and 60 min after e...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(83)90068-0
更新日期:1983-01-01 00:00:00
abstract::In post-natal kittens which were given injections of HRP in the suprasylvian gyrus (polysensory cortex), the cortico-cortical connections were studied qualitatively and quantitatively. These connections originate essentially from cortical cells localized in cortices of the upper part of the hemisphere. They are formed...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(85)90040-1
更新日期:1985-11-01 00:00:00
abstract::Creutzfeldt-Jakob disease (CJD) and other transmissible spongiform encephalopathies (TSEs) are characterised by the accumulation of a pathological conformer of PrP, named PrPsc. Molecular weight and glycosylation of the protease-resistant core of PrPsc (PrP27-30) are heterogeneous in different forms of TSEs. We analys...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(99)00077-5
更新日期:1999-08-01 00:00:00
abstract::Astrocytes are key active elements of the brain that contribute to information processing. They not only provide neurons with metabolic and structural support, but also regulate neurogenesis and brain wiring. Furthermore, astrocytes modulate synaptic activity and plasticity in part by controlling the extracellular spa...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2017.02.001
更新日期:2018-01-01 00:00:00
abstract::We quantitated the activity of ornithine decarboxylase (ODC) in homogenates and subcellular fractions of inner ear tissues from the rat and guinea pig and demonstrate inhibition of cochlear ODC by the aminoglycoside neomycin. Subcellular fractionation showed the enzyme associated with the post-mitochondrial supernatan...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(87)90056-6
更新日期:1987-12-01 00:00:00
abstract::Pregnancy involves changes in brain function that implicate a re-organization in neuronal cytoskeleton. We analyzed the content of the microtubule associated protein Tau (65kDa isoform) and its phosphorylated form (PhosphoTau) in several rat brain regions throughout pregnancy and on day 2 of lactation by Western blot....
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2012.07.011
更新日期:2012-11-01 00:00:00
abstract::The purinergic signaling system, including P2 receptors, plays an important role in various central nervous system (CNS) disorders. Over the last few decades, a substantial amount of accumulated data suggest that most P2 receptor subtypes (P2X1, 2, 3, 4, 6, and 7, and P2Y1, 2, 6, 12, and 13) regulate neuronal/neurogli...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2019.01.030
更新日期:2019-09-01 00:00:00
abstract::Gamma-secretase (GS) is an enzyme complex that cleaves numerous substrates, and it is best known for cleaving amyloid precursor protein (APP) to form amyloid-beta (Aβ) peptides. Aberrant cleavage of APP can lead to Alzheimer's disease, so much research has been done to better understand GS structure and function in ho...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2016.04.019
更新日期:2016-09-01 00:00:00
abstract::Extracellular recordings were made from 467 anti-dromically identified neurosecretory neurons and 148 non-neurosecretory neurons in the paraventricular nucleus of the hypothalamus of hemispherectomized cats under pentobarbital anesthesia. Stimulation of the dorsal, median, and pontine raphe nuclei excited 31%, 26%, an...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(92)90105-7
更新日期:1992-04-01 00:00:00
abstract::After sustaining a traumatic brain injury (TBI), a person's ability to make daily decisions can be affected. Simple tasks such as, deciding what to wear are no longer effortless choices, but are instead difficult decisions. This study explored the use of a discrimination task with a magnesium treatment in order to exa...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2018.02.019
更新日期:2018-05-01 00:00:00
abstract::It has been wildly accepted that willed movement(WM) training promotes neurological rehabilitation in patients with stroke. However, it was not clear whether the effect of WM is better than other forms of exercise. The purpose of this study is to assess different effects of WM and other forms of exercise on rats with ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2015.11.004
更新日期:2016-01-01 00:00:00
abstract::Fibroblast growth factor 9 (FGF9) is a member of the fibroblast growth factor family and is widely expressed in the central nervous system (CNS). However, it is not clear how the working mechanism of FGF9 is involved in cerebellar development. To address this question, we deleted the Fgf9 gene specifically in GABAergi...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2019.10.012
更新日期:2020-01-01 00:00:00
abstract::It has been demonstrated that the posteromedial cortical amygdaloid nucleus (PMCo), is sexually dimorphic. It is shown (Experiment 1) that male orchidectomy on the day of birth (D1) decreases the volume and number of neurons of the PMCo, while a single injection of propionate testosterone to the female on D1 masculini...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(00)00332-4
更新日期:2000-10-01 00:00:00
abstract::The periventricular tissue surrounding the anteroventral third ventricle (AV3V) is critically involved in the maintenance of normal body fluid balance and distribution. The present review examines the anatomical, neurochemical, and functional relationship of the AV3V with neural systems subserving body fluid homeostas...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/0361-9230(85)90209-6
更新日期:1985-12-01 00:00:00
abstract::The vertebrate neural tube consists of a series of neuromeres along its anteroposterior axis. Between amphioxus that possesses no neuromeres and gnathostomes, the lamprey occupies a critical position in the phylogeny for the origin of the segmented brain. To clarify the rhombomeric configuration of the Japanese lampre...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/s0361-9230(01)00669-4
更新日期:2002-02-01 00:00:00
abstract::The distribution of 125I-alpha-bungarotoxin (alpha-BTX), a putative nicotinic cholinergic receptor ligand was studied both in vitro and in vivo in the suprachiasmatic nucleus (SCN), anterior hypothalamic area (AHA), and supraoptic nucleus (SON) of the hypothalamus. For in vitro studies 20 micron frozen frontal section...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(86)90139-5
更新日期:1986-05-01 00:00:00
abstract::We have examined the effects of the presence of the mutated human presenilin 1 gene (M146L; hps1*) on lesion-induced sprouting in the hippocampus of the mouse (C57/CBA). The entorhinal cortex was unilaterally lesioned with ibotenic acid in adult, male mice. Four weeks later the subsequent axonal sprouting in the denta...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(01)00751-1
更新日期:2002-03-15 00:00:00
abstract::Nogo, also known as Reticulon-4, is a protein that is specific to the central nervous system (CNS), and has been identified as an inhibitor of neurite outgrowth. Nogo-A is the largest member of the Nogo family and is responsible for inhibition of CNS regeneration. The structural information and biological functions of...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2012.02.011
更新日期:2012-04-10 00:00:00
abstract::The development of morphine-induced antinociceptive tolerance limits its therapeutic efficacy in pain management. Atorvastatin, or competitive inhibitor of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase, is mainstay agent in hypercholesterolemia treatment. Beyond the cholesterol-lowering activity, exploratio...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2016.07.002
更新日期:2016-07-01 00:00:00
abstract::Sequence variations in genes involved in inflammation system are known to contribute to the risk of cardiovascular diseases (CVD) including stroke. In this study, we performed a genetic association study on the single nucleotide polymorphisms (SNPs) present in the genes CD14 (-159 C/T), TNFalpha (-308 G/A), IL-1alpha ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2007.08.007
更新日期:2008-01-31 00:00:00
abstract::Adenoviral vector directed gene transfer to rat facial motoneurons occurs efficiently following intra-parenchymal injection of relatively high dosages (> or =10(7) pfu per injection) of a prototype first generation adenoviral vector. However, high level of transgene expression, as observed during the first week follow...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(98)00042-2
更新日期:1998-09-15 00:00:00
abstract::The brain serotoninergic (5HTergic) system of epileptic subjects can influence their vulnerability to stress. We studied the putative dependency of 5HT neurotransmission parameters on emotional stress, and the presence, types and severity of seizures using rats with genetic generalized (absence and/or audiogenic) epil...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2006.03.008
更新日期:2006-05-31 00:00:00
abstract::Multiple unit activities (MUA) in 307 brainstem sites were recorded by chronically implanted electrodes in cats, using a polygraph with 4 channel MUA recording units. During transition from waking to slow wave sleep, at 15 sites including the medial preoptic area (11), the diagonal band of Broca (2) and medial anterio...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(88)90108-6
更新日期:1988-06-01 00:00:00
abstract::Parkinson's disease (PD) is mostly known as a dopamine deficiency syndrome due the structural and functional changes in striatal projection neurons. However, studies have considered this pathology as a multi-systemic disease in which the neurodegenerative process extends beyond the dopaminergic system. Therefore, the ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2019.01.009
更新日期:2019-03-01 00:00:00
abstract::A method for constructing a simple spike counter from a conventional calculator by taking advantage of the "adding display to memory" function [(M+) key] is described. The modification involves connecting the (M+) key to a dissecting pin and to a metallic notebook binder which is taped on to a transparent plastic shee...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(83)90017-5
更新日期:1983-12-01 00:00:00