Estradiol masculinizes the posteromedial cortical nucleus of the amygdala in the rat.

abstract：:Bacillus Calmette-Guérin (BCG) is administered to neonates worldwide, but it is still unknown whether this neonatal vaccination affects brain development during early postnatal life, despite the close association of the immune system with the brain. Newborn C57BL/6 mice were injected subcutaneously with BCG or phospha...

journal_title：Brain research bulletin

authors： Yang J,Qi F,Gu H,Zou J,Yang Y,Yuan Q,Yao Z

更新日期：2016-01-01 00:00:00

abstract：:We showed previously that the number and time of spike-wave discharges (SWDs) were increased after intraperitoneal (i.p.) injection of lipopolysaccharide (LPS), an effect, which was completely abolished by cyclooxygenase-2 (COX-2) inhibitor indomethacin (IND) pretreatment in Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats...

journal_title：Brain research bulletin

authors： Kovács Z,Dobolyi A,Juhász G,Kékesi KA

更新日期：2014-05-01 00:00:00

abstract：:Sexually relevant pheromonal cues are detected by the vomeronasal system which includes the posterodorsal part of the medial amygdala, the posteromedial part of the bed nucleus of the stria terminalis and the medial preoptic area. Copulatory behavior is impaired in mice lacking functional aromatase, the enzyme convert...

journal_title：Brain research bulletin

authors： Aste N,Honda S,Harada N

更新日期：2003-05-15 00:00:00

abstract：:Bilateral lesions of the entorhinal cortex (E.C.) of the rat result in persistent deficits in both spontaneous and reinforced alternation. The present study analyzes the nature of this impairment. To determine if changes in exploratory activity accompanied the deficits in alternation, open field activity was measured ...

journal_title：Brain research bulletin

authors： Steward O,Loesche J,Horton WC

更新日期：1977-01-01 00:00:00

abstract：:Rats with chronic hippocampal electrode implants had afterdischarges induced with electrical stimulus intensities of 115, 200, and 800% of a previously determined threshold. Afterdischarge duration, postictal EEG depression duration, and the duration of postictal electrical hypoexcitability were assessed. After discha...

journal_title：Brain research bulletin

authors： Swartzwelder HS,Wegener ST,Johnson CT,Dyer RS

更新日期：1980-09-01 00:00:00

abstract：:In pigeons, the tectofugal system is functionally as well as structurally lateralized. So for example the right nucleus rotundus is less modulated by right forebrain influences than the left nucleus rotundus by the left ones. This functional lateralization pattern may depend on a dynamic balance between left and right...

journal_title：Brain research bulletin

authors： Freund N,Güntürkün O,Manns M

更新日期：2008-03-18 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:Massively obese males often show symptoms of hypogonadism, but the mechanism for this is unclear. Increased endogenous opioid inhibition of the hypothalamic GnRH pulse generator resulting in insufficient stimulation of the pituitary gonadotroph has been proposed as a possible mechanism. If this hypothesis is correct, ...

journal_title：Brain research bulletin

authors： Blank DM,Clark RV,Heymsfield SB,Rudman DR,Blank MS

更新日期：1994-01-01 00:00:00

abstract：:The possible existence of two separate RSA generators in the dorsal hippocampus raises questions as to the degree of coupling or independence of both. In order to answer these questions bipolar EEG recording were made in the CA1 and dentate gyrus of freely moving rats during conditions of RSA generation by different m...

journal_title：Brain research bulletin

authors： Krug M,Brödemann R,Ott T

更新日期：1981-01-01 00:00:00

abstract：:A high correlation between alcohol use and smoking has long been suggested by epidemiological data. We examined the potential behavioral interactions between ethanol and nicotine using ethanol-induced motor incoordination as the test response in mice. Effect of pretreatment of various doses of (-)-nicotine, (-)-cotini...

journal_title：Brain research bulletin

authors： Dar MS,Li C,Bowman ER

更新日期：1993-01-01 00:00:00

abstract：:The influence of gender and stage of the estrous cycle on the levels of acetylcholine, serotonin, and noradrenaline in the hippocampus and on the susceptibility of the cholinergic septo-hippocampal pathway to the neurotoxic effect of ethylcholine aziridinium (AF64A) was investigated in the rat. Levels of acetylcholine...

journal_title：Brain research bulletin

authors： Hörtnagl H,Hansen L,Kindel G,Schneider B,el Tamer A,Hanin I

更新日期：1993-01-01 00:00:00

abstract：:The relationship between the "passions" (emotions or feelings) and psychopathology has been a constant throughout the history of medicine. In this context, melancholy was considered a perversion of the soul (corruption of the passions). One of the most influential authors on this subject was René Descartes, who discus...

journal_title：Brain research bulletin

authors： López-Muñoz F,Rubio G,Molina JD,Alamo C

更新日期：2011-04-25 00:00:00

abstract：:Perinatal exposure to delta 9-THC has been shown to produce effects on brain development. In this study we evaluated the changes induced by maternal exposure to delta 9-THC (5 mg/kg per day) from gestational day 5 to postnatal day 24 in eight discrete brain areas on the central serotoninergic system in both adult male...

journal_title：Brain research bulletin

authors： Molina-Holgado F,Alvarez FJ,Gonzalez I,Antonio MT,Leret ML

更新日期：1997-01-01 00:00:00

abstract：:The dynamics of hypothalamic arginine vasopressin (AVP) release was examined during the development of hypertension in rats with deoxycorticosterone (DOCA)-NaCL induced hypertension. Experiments were performed in four groups of uninephrectomized Sprague-Dawley rats 3, 7, 14 and 21 days after treatment with: (I) DOCA a...

journal_title：Brain research bulletin

authors： Chen YF,Lindheimer MD,Oparil S

更新日期：1986-01-01 00:00:00

abstract：:Brain cytokines have been implicated in brain plasticity and mood alterations. We present here the first evidence of a chronic stress-induced modulation of central cytokines, in absence of experimentally induced inflammatory processes. Several brain areas were extracted from stressed and control mice and cytokines mRN...

journal_title：Brain research bulletin

authors： Bartolomucci A,Palanza P,Parmigiani S,Pederzani T,Merlot E,Neveu PJ,Dantzer R

更新日期：2003-12-30 00:00:00

abstract：:Constant light exposure (LL) can result in "splitting" of circadian rhythms into two components coupled about 12 hr apart. Splitting has been interpreted as evidence for the presence of two main oscillators or groups of oscillators underlying circadian rhythms. Abolition of splitting after unilateral suprachiasmatic n...

journal_title：Brain research bulletin

authors： Harrington ME,Eskes GA,Dickson P,Rusak B

更新日期：1990-04-01 00:00:00

abstract：:Extracellular matrix (ECM) molecules in the central nervous system form highly organized ECM structures around cell somata, axon initial segments, and synapses and play prominent roles in early development by guiding cell migration, neurite outgrowth and synaptogenesis, and by regulating closure of the critical period...

journal_title：Brain research bulletin

authors： Song I,Dityatev A

更新日期：2018-01-01 00:00:00

abstract：:To determine whether repeated exposure of cocaine affects the dopaminergic innervation of the nucleus accumbens, we employed a typical cocaine-dosing regimen in adult male Sprague-Dawley rats followed by an immunocytochemical analysis of tyrosine hydroxylase (TH). Treatment consisted of bi-daily injections of saline o...

journal_title：Brain research bulletin

authors： Todtenkopf MS,De Leon KR,Stellar JR

更新日期：2000-07-15 00:00:00

abstract：:We previously reported that a low threshold action of norepinephrine (NE) on the cerebellar circuitry is expressed as an amplification of the inhibitory action of gamma aminobutyric acid (GABA) on Purkinje cell activity. Here we examined the effects of locus coeruleus (LC) stimulation on "off-beam" inhibitions of Purk...

journal_title：Brain research bulletin

authors： Moises HC,Waterhouse BD,Woodward DJ

更新日期：1983-06-01 00:00:00

abstract：:We studied mitochondria in the satellite cell sheaths which envelope the spinal ganglion neurons of rabbits aged 12, 42, and 79 months. While the mean cytoplasmic volume of satellite cell sheaths did not change significantly with age, the mean percentage of cytoplasmic volume occupied by mitochondria decreased with ag...

journal_title：Brain research bulletin

authors： Martinelli C,Sartori P,Ledda M,Pannese E

更新日期：2003-07-15 00:00:00

abstract：:We examined some developmental and behavioral sequelae of exposing Binghamton Heterogeneous Stock (HET) mice to a 0.5% aqueous lead acetate solution (as the only available fluid source) for either none, one, two, or three generations. Lead exposure, regardless of generation, resulted in decreased body weight and a del...

journal_title：Brain research bulletin

authors： Rasile DA,Stewart PW,Burright RG,Donovick PJ

更新日期：1995-01-01 00:00:00

abstract：:Complex interactions between genetic and environmental factors exert a sustained influence on the pathogenesis of schizophrenia (SCZ). Adolescent social isolation is regarded as a typical paradigm for SCZ. However, the underlying pathological mechanisms are not fully understood. In this study, adolescent Sprague-Dawle...

journal_title：Brain research bulletin

authors： Sun L,Min L,Li M,Shao F,Wang W

更新日期：2018-09-01 00:00:00

abstract：:Cell-free incorporation of (14C) leucine into protein was 38% greater for cerebral cortical microsomes from 22-day old neonatally thyroidectomized rats compared to littermate controls. In contrast, incorporation by liver microsomes of hypothyroid rats was 33% lower compared to controls, confirming their deficient horm...

journal_title：Brain research bulletin

authors： Gonzales LW,Geel SE

更新日期：1980-01-01 00:00:00

abstract：:Depression is the root of various diseases. It is one of the most debilitating conditions globally. Antidepressant drugs are usually the first-line of depression treatment. Arctigenin (ARC), one of active ingredient of Arctium lappa L, has been found to exert neuroprotective, anti-decrepitude, and anti-inflammatory ac...

journal_title：Brain research bulletin

authors： Du Y,Li W,Li Y,Yang J,Wang X,Yin S,Wang X,Velez de-la-Paz OI,Gao Y,Chen H,Yin X,Shi H

更新日期：2019-03-01 00:00:00

abstract：:The gonadotrophin-releasing hormone 1 (GnRH1) system has been investigated immunohistochemically in Cape dune mole-rats (Bathyergus suillus), subterranean rodents that normally display severe aggression towards conspecifics. These animals breed seasonally and show a reduced mean plasma level of luteinising hormone dur...

journal_title：Brain research bulletin

authors： Hart L,Bennett NC,Kalamatianos T,Oosthuizen MK,Jarvis JU,O'Riain MJ,Coen CW

更新日期：2008-10-22 00:00:00

abstract：:Rats were tested in the elevated plus-maze test of anxiety after a probe injection of chlordiazepoxide (CDP 5 mg/kg) following short-term (5 days) or long-term (20 days) pretreatment with 5 or 20 mg/kg/day. After short-term pretreatment with either dose, the probe dose had anxiolytic effects (it increased the % number...

journal_title：Brain research bulletin

authors： File SE,Baldwin HA,Aranko K

更新日期：1987-11-01 00:00:00

abstract：:Until now, economic theory has not systematically integrated the influence of emotions on decision-making. Since evidence from neuroscience suggests that decision-making as hypothesized in economic theory depends on prior emotional processing, interdisciplinary research under the label of "neuroeconomics" arose. The k...

journal_title：Brain research bulletin

authors： Kenning P,Plassmann H

更新日期：2005-11-15 00:00:00

abstract：:The microdialysis method was utilized to study the effects of N omega-nitro-L-arginine (L-NNA) and N omega-nitro-D-arginine (D-NNA), an inhibitor of nitric oxide (NO) synthesis from L-arginine and its D-enantiomer, on spontaneous and N-methyl-D-aspartate (NMDA)-evoked overflow of striatal extracellular dopamine (DA) i...

journal_title：Brain research bulletin

authors： Ishida Y,Yamamoto R,Mitsuyama Y

更新日期：1994-01-01 00:00:00

abstract：:In people with Huntington's disease, an expanded CAG repeat sequence on the HTT gene confers a toxic gain function resulting in a progressive and fatal neurodegeneration. The Hdh((CAG)Q150) Huntington's disease mouse line is a knock-in model of the disease that carries ∼150 CAG repeats on the normal mouse Htt locus. T...

journal_title：Brain research bulletin

authors： Brooks S,Higgs G,Jones L,Dunnett SB

更新日期：2012-06-01 00:00:00

abstract：:Calcium channels affect many neuronal functions, including membrane electrical excitability, synaptic transmission, cellular homeostasis, gene transcription, growth, and development. We used recently developed methods for serum-free culture of adult and embryonic rat neurons to study the development of voltage-sensiti...

journal_title：Brain research bulletin

authors： Collings MA,Brewer GJ,Evans MS

更新日期：1999-01-01 00:00:00