Abstract：
:In our earlier studies we have observed that T lymphocytes of dengue type 2 virus (DV)-infected mouse spleen produce a cytotoxic factor (CF). In the present study it has been observed that CF induces mouse spleen and peritoneal macrophages to produce a cytotoxin (CF2) as has been revealed by DEAE-cellulose chromatography. CF2 is produced by an induction process and is present intracellularly as well as leaking out of the cells. CF2 kills most of the macrophages and some of the T cells, as observed with CF. It appears that CF2 is produced to amplify the effect of CF and/or for cooperative action with CF.
journal_name
Immunologyjournal_title
Immunologyauthors
Gulati L,Chaturvedi UC,Mathur Asubject
Has Abstractpub_date
1983-05-01 00:00:00pages
121-30issue
1eissn
0019-2805issn
1365-2567journal_volume
49pub_type
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