Biliary tree in cystic fibrosis. Biliary tract abnormalities in cystic fibrosis demonstrated by endoscopic retrograde cholangiography.

abstract：:Gastrointestinal symptoms occur in a large number of patients with food allergies. Immediate hypersensitivity mechanisms may give rise to the nausea, vomiting, abdominal pain, and diarrhea experienced by these patients. However, there are limited human data about the pathophysiological basis for these symptoms. Most o...

journal_title：Gastroenterology

authors： Crowe SE,Perdue MH

更新日期：1992-09-01 00:00:00

abstract：:Rising trends in the incidence and mortality of early-onset CRC in those who are ages less than 50 years have been well-established. These trends have spurred intense investigation focused on elucidating the epidemiology and characteristics of early-onset CRC, as well on identifying strategies for early detection and ...

journal_title：Gastroenterology

authors： Burnett-Hartman AN,Lee JK,Demb J,Gupta S

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND & AIMS:We performed a prospective, randomized, controlled study to compare the combination of esomeprazole and clopidogrel vs clopidogrel alone in preventing recurrent peptic ulcers in patients with atherosclerosis and a history of peptic ulcers. We also investigated the effects of esomeprazole on the antipl...

journal_title：Gastroenterology

authors： Hsu PI,Lai KH,Liu CP

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND/AIMS:Hepatic vein thrombosis is thought to be manifested by ascites, abdominal pain, and hepatomegaly, with a uniformly poor prognosis. However, new imaging techniques allow for the diagnosis of hepatic vein thrombosis in asymptomatic cases. The aim of our study was to re-evaluate symptoms and prognosis in p...

journal_title：Gastroenterology

authors： Hadengue A,Poliquin M,Vilgrain V,Belghiti J,Degott C,Erlinger S,Benhamou JP

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND & AIMS:Induction of colitis in mice by administration of oxazolone is mediated by T-helper (Th) 2 cells and has features of human ulcerative colitis. We investigated whether activation of interleukin (IL)-4Rα on T and B cells determines their effector functions and mediates oxazolone-induced colitis. METHOD...

journal_title：Gastroenterology

authors： Hoving JC,Kirstein F,Nieuwenhuizen NE,Fick LC,Hobeika E,Reth M,Brombacher F

更新日期：2012-01-01 00:00:00

abstract：:Canine ileal segments were luminally perfused with known amounts of polyethylene glycol (PEG), and samples obtained were freed of protein by a cold acetone (CA) method and assayed for PEG by trichloroacetic acid in the presence of calcium cations. This procedure was compared to the Barium salt (BaS) protein precipitat...

journal_title：Gastroenterology

authors： Buxton TB,Crockett JK,Moore WL 3rd,Moore WL Jr,Rissing JP

更新日期：1979-04-01 00:00:00

abstract：:Reduction in caloric intake was associated with a greater absolute rise in the serum bilirubin concentration in patients with Gilbert's syndrome and partial hepatic bilirubin uridine diphosphate glucuronyltransferase (UDPG-T) dysfunction compared to patients with hemolytic unconjugated hyperbilirubinemia and normal su...

journal_title：Gastroenterology

authors： Felsher BF,Carpio NM

更新日期：1975-07-01 00:00:00

abstract：:Polycystic liver diseases (PLD) are inherited disorders of the biliary epithelium, caused by genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic reticulum and the cilium. PLD are characterized by the formation and progressive enlargement of multiple cysts scattered throughout t...

journal_title：Gastroenterology

authors： Strazzabosco M,Somlo S

更新日期：2011-06-01 00:00:00

abstract：:The purpose of this study was to determine whether gamma-hydroxybutyrate provides protection against intestinal ischemia/reperfusion injury and to compare its effect with that of allopurinol and vitamin E. Thirty minutes of total regional ischemia, followed by 3 hours of reperfusion, produced intestinal damage that wa...

journal_title：Gastroenterology

authors： Boyd AJ,Sherman IA,Saibil FG,Mamelak M

更新日期：1990-09-01 00:00:00

abstract：:There are apparent similarities in the mechanisms of the intestinal phase of exocrine and pancreatic polypeptide (PP) secretion by the pancreas. To characterize this relationship, we measured incremental responses of protein, bicarbonate, and PP to graded doses of intravenous secretin, caerulein, CCK8, CCK33, bethanec...

journal_title：Gastroenterology

authors： Beglinger C,Taylor IL,Grossman MI,Solomon TE

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND & AIMS:Confocal laser endomicroscopy (CLE) is a technique that permits real-time detection and quantification of changes in intestinal tissues and cells, including increases in intraepithelial lymphocytes and fluid extravasation through epithelial leaks. Using CLE analysis of patients with irritable bowel sy...

journal_title：Gastroenterology

authors： Fritscher-Ravens A,Pflaum T,Mösinger M,Ruchay Z,Röcken C,Milla PJ,Das M,Böttner M,Wedel T,Schuppan D

更新日期：2019-07-01 00:00:00

abstract：:The intracellular pH (pHi) of isolated hamster intestinal cells was determined with three techniques: the null-point method with digitonin, the distribution of the weak acid 5,5-dimethyloxazolidine-2,4-dione, and the trapped fluorescent indicator 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein. In physiologic saline, ...

journal_title：Gastroenterology

authors： Goré J,Hoinard C

更新日期：1989-10-01 00:00:00

abstract：:Phenobarbital response, bile pigment composition, and the fractional biliary excretion ratio of bilirubin were studied in nine children with Crigler-Najjar disease. In five children, serum bilirubin levels decreased during phenobarbital treatment by 26% or more and the pigment composition in bile changed with a decrea...

journal_title：Gastroenterology

authors： Sinaasappel M,Jansen PL

更新日期：1991-03-01 00:00:00

abstract：:We report the case of a patient in whom amitriptyline administration for 5 wk was followed by prolonged cholestasis. Jaundice and pruritus lasted 19 and 20 mo, respectively. Three liver biopsies were performed at different stages of the disease showing the course of liver lesions. Cholestasis initially located in the ...

journal_title：Gastroenterology

authors： Larrey D,Amouyal G,Pessayre D,Degott C,Danne O,Machayekhi JP,Feldmann G,Benhamou JP

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND & AIMS:The basic mechanisms of food allergies are still unknown. The aims of this study were to investigate whether endothelins (ETs) in the intestinal mucosa are involved in the pathogenesis of intestinal anaphylaxis. METHODS:Sprague-Dawley rats were sensitized to chicken egg albumin (EA) by intraperitonea...

journal_title：Gastroenterology

authors： Shigematsu T,Miura S,Hirokawa M,Hokari R,Higuchi H,Tsuzuki Y,Kimura H,Nakatsumi RC,Serizawa H,Saito H,Ishii H

更新日期：1998-08-01 00:00:00

abstract：:In humans and most other species, a decline in pH of gallbladder contents occurs during the concentration of bile. Recent in vitro studies in rabbit, guinea pig, and Necturus gallbladders have strongly suggested mucosal H+ secretion during sodium reabsorption, presumably representing a Na+/H+ exchange. The present in ...

journal_title：Gastroenterology

authors： Rege RV,Moore EW

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND & AIMS:T helper (Th) 17 cells that express the retinoid-related orphan receptor (ROR) γt contribute to the development of colitis in mice, yet are found in normal and inflamed intestine. We investigated their development and functions in intestines of mice. METHODS:We analyzed intestinal Th17 cells in healt...

journal_title：Gastroenterology

authors： Ono Y,Kanai T,Sujino T,Nemoto Y,Kanai Y,Mikami Y,Hayashi A,Matsumoto A,Takaishi H,Ogata H,Matsuoka K,Hisamatsu T,Watanabe M,Hibi T

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatic mucinous cystic neoplasm (MCN), a cystic tumor of the pancreas that develops most frequently in women, is a potential precursor to pancreatic ductal adenocarcinoma. MCNs develop primarily in the body and tail of the pancreas and are characterized by the presence of a mucinous epithelium and...

journal_title：Gastroenterology

authors： Sano M,Driscoll DR,De Jesus-Monge WE,Klimstra DS,Lewis BC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanism by which antimicrobial therapy against Helicobacter pylori is enhanced by acid suppression is unknown. The aim of this study was to investigate the effect of omeprazole on gastric juice, plasma, and saliva concentrations of metronidazole, amoxicillin, and clarithromycin. METHODS:Single ...

journal_title：Gastroenterology

authors： Goddard AF,Jessa MJ,Barrett DA,Shaw PN,Idström JP,Cederberg C,Spiller RC

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND/AIMS:Liver fat-storing cells (FSCs) actively proliferate and secrete extracellular matrix during liver injury. Platelet-derived growth factor (PDGF) is a potent mitogen for cultured FSCs. In the present study, we investigated the regulation of PDGF gene expression and production in cultured human liver FSCs....

journal_title：Gastroenterology

authors： Marra F,Choudhury GG,Pinzani M,Abboud HE

更新日期：1994-10-01 00:00:00

abstract：:Human gastrointestinal cancer xenografts were established in the nude mouse. Grafts were accomplished with gastric adenocarcinomas, gastric leiomyosarcoma, histiocytic lymphoma of the stomach and gallbladder, pancreatic tumors, colonic cancers and cell lines of duodenal (HUTU-80) and pancreatic (HS-766-T) cancers, mel...

journal_title：Gastroenterology

authors： Schmidt M,Deschner EE,Thaler HT,Clements L,Good RA

更新日期：1977-05-01 00:00:00

abstract：:The role of central (supraspinal and spinal) and peripheral alpha-adrenoceptors in the regulation of gastrointestinal propulsion in the mouse was studied using clonidine, an alpha 2-adrenoceptor agonist. Clonidine produced a dose-dependent inhibition of propulsion when given intracerebroventricularly, intrathecally, o...

journal_title：Gastroenterology

authors： Jiang Q,Sheldon RJ,Porreca F

更新日期：1988-11-01 00:00:00

abstract：:A 22-yr-old woman with a 7-yr history of systemic lupus erythematosus presented with anasarca and a serum albumin of 0.8 g/dl. Renal and hepatic function were near normal; the major route of protein loss appeared to be the intestine. A full-thickness section of jejunum obtained at laparotomy demonstrated a severe, dif...

journal_title：Gastroenterology

authors： Weiser MM,Andres GA,Brentjens JR,Evans JT,Reichlin M

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The peptidyl prolyl isomerase Pin1 frequently is overexpressed in hepatocellular carcinoma (HCC). Hepatitis B virus (HBV) is the most common etiologic agent in HCC, and its encoded X-protein (HBx) is oncogenic and possesses a serine-proline motif that may bind Pin1. The role of Pin1 in hepatocarcino...

journal_title：Gastroenterology

authors： Pang R,Lee TK,Poon RT,Fan ST,Wong KB,Kwong YL,Tse E

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND & AIMS:The Forkhead box gene, group O (FoxO) family of Forkhead transcription factors is phopsphorylated and inactivated by the phosphatidylinositol 3-kinase (PI3K)/AKT pathway and regulates a variety of cellular functions. Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis. A fibrotic stimu...

journal_title：Gastroenterology

authors： Adachi M,Osawa Y,Uchinami H,Kitamura T,Accili D,Brenner DA

更新日期：2007-04-01 00:00:00

abstract：:The clinical case is presented of a 16-yr-old patient with thoracoabdominal duplication that communicated with the main pancreatic duct and the right pleural cavity and resulted in pancreaticopleural fistula. Although abdominal duplications communicating with the pancreas have been described before, to our knowledge, ...

journal_title：Gastroenterology

authors： Fitzgibbons RJ Jr,Nugent FW,Ellis FH Jr,Braasch JW,Scholz FJ

更新日期：1980-08-01 00:00:00

abstract：:The effects of some newly developed tachykinin antagonists that are selective for the neurokinin (NK)-1 (L 668,169) or the NK-2 (MEN 10,207, L 659,877 and R 396) tachykinin receptor on the cholinergic and noncholinergic contraction and on the nonadrenergic noncholinergic relaxation produced by electrical field stimula...

journal_title：Gastroenterology

authors： Maggi CA,Giuliani S,Patacchini R,Santicioli P,Theodorsson E,Barbanti G,Turini D,Giachetti A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND & AIMS:Development of pancreatic ductal adenocarcinoma (PDA) involves acinar to ductal metaplasia and genesis of tuft cells. It has been a challenge to study these rare cells because of the lack of animal models. We investigated the role of tuft cells in pancreatic tumorigenesis. METHODS:We performed studie...

journal_title：Gastroenterology

authors： DelGiorno KE,Chung CY,Vavinskaya V,Maurer HC,Novak SW,Lytle NK,Ma Z,Giraddi RR,Wang D,Fang L,Naeem RF,Andrade LR,Ali WH,Tseng H,Tsui C,Gubbala VB,Ridinger-Saison M,Ohmoto M,Erikson GA,O'Connor C,Shokhirev MN,Hah

更新日期：2020-11-01 00:00:00

abstract：:The effects of IV injection of 5-hydroxytryptamine 3 receptor antagonists (BRL 43694 and GR38032F) on gastrointestinal contractile activity were studied in dogs with vagally denervated fundic pouch in the conscious state by means of chronically implanted force transducers in the gastrointestinal tract and the pouch. I...

journal_title：Gastroenterology

authors： Itoh Z,Mizumoto A,Iwanaga Y,Yoshida N,Torii K,Wakabayashi K

更新日期：1991-04-01 00:00:00

abstract：:Furosemide occasionally causes azotemia in patients with ascites, independently of induced volume depletion. To define this effect, we measured renal clearances in patients with chronic liver disease and ascites and in nonascitic controls. Furosemide (80 mg i.v.) transiently increased p-aminohippurate clearance in con...

journal_title：Gastroenterology

authors： Daskalopoulos G,Laffi G,Morgan T,Pinzani M,Harley H,Reynolds T,Zipser RD

更新日期：1987-06-01 00:00:00