Abstract:
:Pineal glands were collected from superior cervical ganglionectomized (SCGX) and sham-treated rats at time intervals following surgical manipulation. Pineal noradrenaline (NA) levels were quantitated by a radioisotopic-enzyme technique, or the pineals were examined by histofluorescence or electron microscopic techniques. A significant decline in pineal NA content was observed by 12 hours with a virtual disappearance of NA by 24 hours following SCGX. The depletion of NA content correlated with the disappearance of synaptic vesicles and the appearance of generalized fine structural degeneration of the sympathetic nerve endings in the pineals. Then results indicate that less than one day is required to remove all of the potentially, functional neurotransmitter from the denervated pineal gland. These observations agree closely with the time course of degeneration of other sympathetic nerve terminals following SCGX.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Morgan WW,Hansen JTdoi
10.1007/BF00238713subject
Has Abstractpub_date
1978-07-14 00:00:00pages
429-34issue
3eissn
0014-4819issn
1432-1106journal_volume
32pub_type
杂志文章abstract::Extracellular recordings were made from the nucleus ambiguous in three conscious Macaca nemestrina monkeys during spontaneous vocalizations and swallows. The temporal relationship of neuronal activity to swallowing was inferred through correlation with the thyroarytenoid electromyographic (EMG) activity. Videofluorosc...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227276
更新日期:1994-01-01 00:00:00
abstract::The present study examined the dopaminergic innervation of the rat globus pallidus by in vivo microdialysis and immunohistochemistry in more detail. Using tyrosine hydroxylase immunohistochemistry, two classes of dopaminergic fibers were distinguished morphologically in the globus pallidus. Unilateral infusion of 6-hy...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1638-7
更新日期:2004-01-01 00:00:00
abstract::Chronic pain and gait variability in a dual-task situation are both associated with higher risk of falling. Executive functions regulate (dual-task) gait variability. A possible cause explaining why chronic pain increases risk of falling in an everyday dual-task situation might be that pain interferes with executive f...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4039-1
更新日期:2014-11-01 00:00:00
abstract::Rhythmic movement patterns between the hands in response to environmental signals are studied in normal (musicians and nonmusicians) and split-brain subjects. Only two phase-locked states - in-phase and anti-phase - are shown to be stable for all subjects. Split-brain subjects show an even greater attraction to these ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247936
更新日期:1989-01-01 00:00:00
abstract::A wealth of evidence describes the strong positive impact that reward has on motor control at the behavioural level. However, surprisingly little is known regarding the neural mechanisms which underpin these effects, beyond a reliance on the dopaminergic system. In recent work, we developed a task that enabled the dis...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05802-1
更新日期:2020-08-01 00:00:00
abstract::Blinks are known to affect eye movements, e.g., saccades, slow and fast vergence, and saccade-vergence interaction, in two ways: by superimposition of blink-associated eye movements and changes of the central premotor activity in the brainstem. The goal of this study was to determine, for the first time, the effects o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2040-9
更新日期:2005-02-01 00:00:00
abstract::The overlap of dominant tremor frequencies and similarly amplified tremor observed for Parkinson's disease (PD) and essential tremor (ET) means differentiating between these pathologies is often difficult. As tremor exhibits non-linear properties, employing both linear and non-linear analyses may help distinguish betw...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-4924-5
更新日期:2017-06-01 00:00:00
abstract::The current study examined the EEG of young, old and old declined adults performing a visual paired associate task. In order to examine the effects of encoding context and stimulus repetition, target pairs were presented on either detailed or white backgrounds and were repeatedly presented during both early and late p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2966-7
更新日期:2012-02-01 00:00:00
abstract::Static and dynamic otolith, horizontal vestibular and optokinetic ocular reflexes were investigated in pigmented rats 1-6 and more months after unilateral vestibular nerve (UVN) section. Evoked responses were compared with published data from control rats studied under identical conditions. Static lateral tilt of UVN ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050287
更新日期:1998-02-01 00:00:00
abstract::Previous studies have shown that the vestibular short-latency-evoked potential (VsEP) in response to the brief head acceleration stimulus is a compound action potential of neurons innervating the otolith organs. However, due to the lack of direct evidence, it is currently unclear whether the VsEP is primarily generate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3602-5
更新日期:2013-08-01 00:00:00
abstract::The effects of learning on strategy selection in the context of action imitation have been investigated in two experiments conducted with healthy individuals. It was predicted that, once learnt, meaningless actions are processed by the cognitive system as meaningful and this new representational status might influence...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-006-0395-9
更新日期:2006-08-01 00:00:00
abstract::Scientific interest has increased the influence of temperature in neurodegenerative and psychiatric disorders, and according to the monoamine hypothesis, depression is a neurochemical disorder arising from hypofunctioning of brain monoamine systems. Here, in vivo flow-oxymetry is applied to verify relationships betwee...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3443-2
更新日期:2013-10-01 00:00:00
abstract::In the thalamic ventrobasal complex (VB) of the cat, effects of electrical stimulation of the pyramidal tract (PT) upon activities of 112 relay cells and 18 internuncial cells were examined. Single PT shocks to the cerebral peduncle elicited short-latency discharges in 31 relay cells (mean latency, 1.4 +/- 0.5 msec). ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00234770
更新日期:1975-03-27 00:00:00
abstract::It is widely believed that cells in area 17 send axons specifically to neurons in other cortical areas whose receptive fields coincide with their own. We asked whether this was true in cats for area 17's projection to a large suprasylvian visual area, the Clare-Bishop area. Receptive fields were plotted at multiple si...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00250246
更新日期:1988-01-01 00:00:00
abstract::Sinusoidal translation while rotating at constant angular velocity about a vertical axis (translation while rotating, TWR) produces centripetal and translational accelerations along the direction of translation and an orthogonal Coriolis acceleration due to the translation in the rotating frame. Thus, a Coriolis accel...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2178-5
更新日期:2005-06-01 00:00:00
abstract::The egocentric localization of objects in extrapersonal space requires that the retinal and extraretinal signals specifying the gaze direction be simultaneously processed. The question as to whether the extraretinal signal is of central or peripheral origin is still a matter of controversy, however. Three experiments ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229419
更新日期:1991-01-01 00:00:00
abstract::We have reported previously that intracranial application of near-infrared light (NIr) reduces clinical signs and offers neuroprotection in a subacute MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) monkey model of Parkinson's disease. In this study, we explored whether NIr reduces the gliosis in this animal model...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4720-7
更新日期:2016-11-01 00:00:00
abstract::Despite holding significant promise for counteracting the deleterious effects of ageing on cognitive and motor function, little is known of the effects of facilitatory non-invasive brain stimulation (NBS) techniques on corticospinal excitability (CSE) in older adults. Thirty-three older adults (≥60 years) participated...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4740-3
更新日期:2016-12-01 00:00:00
abstract::When reaches are performed toward target objects, the presence of other non-target objects influences kinematic parameters of the reach. A typical observation has been that non-targets positioned ipsilaterally to the acting limb interfere more with the trajectory of the hand than contralateral non-targets. Here, we in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3615-0
更新日期:2013-09-01 00:00:00
abstract::The output from a motor nucleus is determined by the synaptic input to the motor neurons and their intrinsic properties. Here, we explore whether the source of synaptic inputs to the motor neurons (cats) and the age or post-stroke conditions (humans) may change the recruitment gain of the motor neuron pool. In cats, t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05628-6
更新日期:2019-11-01 00:00:00
abstract::Fetal spinal cord tissue was grafted to the anterior chamber of the eye of adult recipients. Transverse segments from the cervical and high thoracic levels were divided in halves which were grafted directly or further divided into ventral horn and dorsal horn parts before grafting. Survival and intraocular growth was ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237016
更新日期:1985-01-01 00:00:00
abstract::The distribution of anterogradely-labeled fibers and retrogradely-labeled cell bodies in the interpeduncular nucleus (IPN) was mapped after injections of wheat-germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) into various structures of the basal forebrain in adult rats. WGA-HRP injections into the medial...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00279657
更新日期:1988-01-01 00:00:00
abstract::Previous data have indicated that, if guinea pigs are deprived of all visual information during a crucial period early in development (26-30 days after birth), the map of auditory space in the superior colliculus (SC) is completely disrupted. In the experiments reported here, multi-unit auditory receptive fields were ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00241121
更新日期:1995-01-01 00:00:00
abstract::In the present article, we summarize the recent progress on investigating the mechanism of corticofugal modulation on the auditory thalamus of mammals excluding the bat as it has a specialized auditory system. The article comprises: (1) a review of the anatomy and physiology of the auditory thalamus, and a discussion ...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-003-1680-5
更新日期:2003-12-01 00:00:00
abstract::Both human and animal research indicate that rapid eye movement sleep (REM) plays an important role in the processing of emotional information. REM is altered after fear conditioning in rats, but this alteration can be mitigated by exposure to a naïve conspecific. In addition, both the housing condition (isolated vs p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3828-x
更新日期:2014-05-01 00:00:00
abstract::In earlier studies the tetrahydroisoquinoline derivative N-methyl-norsalsolinol (2-MDTIQ) was discovered in lumbar cerebrospinal fluid and brain of patients with Parkinson's disease. To establish whether 2-MDTIQ is toxic to the dopaminergic system, 2-MDTIQ or 6-hydroxydopamine (6-OHDA) were stereotactically injected i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227181
更新日期:1996-11-01 00:00:00
abstract::Our recent work has revealed that visuospatial working memory (VSWM) relates to the rate of explicit motor sequence learning (Bo and Seidler in J Neurophysiol 101:3116-3125, 2009) and implicit sequence performance (Bo et al. in Exp Brain Res 214:73-81, 2011a) in young adults (YA). Although aging has a detrimental impa...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3189-2
更新日期:2012-09-01 00:00:00
abstract::The gain of the vestibulo-ocular reflex (VOR) of intact pigmented rats was adaptively modified by training protocols that created a visual-vestibular conflict. For training, head restrained animals were oscillated on a turntable in front of an optokinetic pattern projected onto a cylindrical wall. The optokinetic patt...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230530
更新日期:1991-01-01 00:00:00
abstract::The information transmitted (Ti) by the direction of two-dimensional (2-D) isometric forces at different stereoscopic depths was studied in 50 naive human subjects using an isometric manipulandum and random dot stereograms generated in a color display (Massey et al. 1988). Subjects viewed the display through appropria...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231170
更新日期:1991-01-01 00:00:00
abstract::Single unit activity was studied in the dorsomedial edge of the frontal lobe, above the superior arcuate sulcus in three trained monkeys (Macaca nemestrina). Gaze and head movements were recorded with two magnetic search coils. Discharges preceding spontaneous eye movements in a preferred direction were consistently o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238971
更新日期:1985-01-01 00:00:00