Abstract:
:Calcification is the most characteristic pathologic feature of healed meconium peritonitis. Occurrence of calcification in meconium peritonitis has been reported, but its mechanism has not been discussed. According to our studies, the cause of calcification and giant cell reaction is meconium peritonitis is related to several distinct factors leading to three morphologic presentations described under type I, II and III in this paper. These factors can be traced to components of meconium. These morphologic findings are specific and in the proper context diagnostic of meconium peritonitis.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Forouhar Fdoi
10.1016/0306-9877(84)90062-8subject
Has Abstractpub_date
1984-05-01 00:00:00pages
51-6issue
1eissn
0306-9877issn
1532-2777pii
0306-9877(84)90062-8journal_volume
14pub_type
杂志文章abstract::Articles dealing with the epidemiological aspects of asthma were carefully reviewed in order to support or reject our clinical impression of increased rate of asthma among immigrants. Particular emphasis was put on data on very high or very low rates of asthma. The proposed theories to explain these differences were c...
journal_title:Medical hypotheses
pub_type: 杂志文章,meta分析
doi:10.1016/s0306-9877(98)90047-0
更新日期:1998-10-01 00:00:00
abstract::Random connection weight disturbances within an assembly of artificial neural networks (ANN) drive a progression of activation patterns that are tantamount to the memories and ideas nucleating within the brain's cortex. The numerical evaluation of these pattern-based notions by another, more placid system of ANNs gove...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2016.07.010
更新日期:2016-09-01 00:00:00
abstract::Recent findings indicate a principal role for Hepcidin in iron homeostasis. Hepcidin is also thought to play a vital role in the pathogenic mechanism of anaemia in patients with inflammation or chronic disease. Under normal conditions influx and efflux of iron from duodenal enterocytes is regulated by Ferroportin. Fer...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2007.10.007
更新日期:2008-01-01 00:00:00
abstract::In the early postnatal period, intraventricular hemorrhage may develop in infants with extremely low birth weights due to hemodynamic instability. One of the most significant factors in intraventricular hemorrhage development is fluctuations in the cerebral blood flow due to left-to-right shunting as a result of paten...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2018.07.013
更新日期:2018-10-01 00:00:00
abstract::This thesis explores the activation of chemicals in metabolic systems from the viewpoint that this activation is under the control of elements of the space-sea in which the chemicals are immersed. Themselves inert, the chemicals are theorised to exploit a force or action issuing from space (fluctuation) and characteri...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2001.1298
更新日期:2001-07-01 00:00:00
abstract::Keratoacanthomas have many characteristics of squamous cell carcinoma and in the past were interpreted as squamous cell carcinomas. It is now known that these lesions spontaneously resolve if left untreated. In man the lesions occur on sunlight damaged areas or areas exposed to tar. Many of the experimental cancers of...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(88)90063-1
更新日期:1988-06-01 00:00:00
abstract::It is hypothesized that Alzheimer's disease is a human phylogenetic disease which has a common multifactorial pathogenesis in sporadic and familial cases and in Down syndrome, related to a genomic character function G(x). Increments in G(x) accompanied the increased gene expression that sustained brain growth and diff...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(89)90185-0
更新日期:1989-07-01 00:00:00
abstract::Persistently infecting DNA viruses depend heavily on host cell DNA synthesis machinery. Replication of cellular and viral DNA is inhibited by mutagenic stress. It is hypothesized that diurnal regulation of viral DNA replication may occur at the level of cell cycle checkpoints and DNA repair, to protect DNA from exposu...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2006.08.018
更新日期:2007-01-01 00:00:00
abstract::Foster found areas with the highest incidence of SIDS in USA in 1983-1984 coincided with the highest areas recorded with the highest incidence of goitre in First World War troops (1). Reid compared the two populations described as having the highest incidence of SIDS worldwide. Both were selenium deficient areas (King...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(94)90124-4
更新日期:1994-04-01 00:00:00
abstract::In this editorial, we provide concise suggestions to help individuals decide what scientific papers to read and how to read them. We do so because--like others--we are frequently asked by people with interest in science as to how to effectively surf today's information tsunami. This is particularly important in, but n...
journal_title:Medical hypotheses
pub_type: 社论
doi:10.1016/j.mehy.2009.05.002
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:In smoking cessation trials, placebo response rates are reported to be rather low, and they are lowest when compared to the placebo response rates of treatment of other addictions. We hypothesized that high placebo response rates in trials outside of cessation treatment may predict low participation of smoke...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.06.012
更新日期:2014-09-01 00:00:00
abstract::Over the last century and a half there has been a secular decline in the age of menarche in Western, industrialized cultures. This trend has been largely ascribed to improved nutrition and health, and we offer an alternative hypothesis that changes in socio-economic conditions have resulted in changes in the pheromona...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(85)90018-0
更新日期:1985-05-01 00:00:00
abstract::Extracellular matrix metalloproteinase inducer (EMMPRIN), which is also called BASIGIN/CD147, is a cell surface glycoprotein that belongs to the immunoglobulin superfamily and plays a significant role in intercellular recognition in immunology, cellular differentiation and development. Apart from ACE-2, recently EMMPR...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2020.110089
更新日期:2020-10-01 00:00:00
abstract::Non-union after bone fracture is rather common with an increasing frequency of incidence rate due to poorly treated early operations, among which the mechanism of atrophic non-union remains unclear. Previous opinions showed that impaired blood supply of affected limbs might mostly contribute to the atrophic non-union,...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2011.03.027
更新日期:2011-07-01 00:00:00
abstract::At present no good method of assisting the right ventricle of the heart exists. This paper presents a new and effective approach to assisting the right ventricle of the heart which can be utilized independently or during cardiac surgery. Through implementation of this method, and timed inflation and deflation of sever...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(79)90003-3
更新日期:1979-11-01 00:00:00
abstract::Evidence from clinical and experimental studies has shown that placebos influence mood and behavior, that endogenous opioids are involved in the placebo effect, and that the endogenous opioid system is related to psychological events. Recent studies have also demonstrated that the endogenous opioid system is closely c...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(97)90105-5
更新日期:1997-04-01 00:00:00
abstract::Lysosomes, lysosomal enzymes and oxidant processes are known to be involved in cancer processes. The prostasomes contain proteins and enzymes that would constitute pathways for the hydrolysis of proteins and peptides. However, integrated biochemical and cell biology studies are necessary to understand how lysosomal en...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2004.11.039
更新日期:2005-01-01 00:00:00
abstract::Hyperemesis gravidarum (HG) is the most severe form of illness within the spectrum of nausea and vomiting of pregnancy. Liver disease, usually consisting of mild serum transaminase elevation, occurs in almost 50% of patients with HG. While multiple risk factors have been proposed, the etiology and underlying mechanism...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2005.05.035
更新日期:2005-01-01 00:00:00
abstract::Emerging evidences indicate that elevated cholesterol and triglyceride levels precede Alzheimer's disease (AD) pathology. High caloric intake based on saturated fat raises hyperlipidaemia and also promotes AD pathology. As a result, strategy that limits the absorption of dietary fat and attenuates hyperlipidemia could...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2009.04.046
更新日期:2009-11-01 00:00:00
abstract::Chronic idiopathic axonal polyneuropathy (CIAP) is referred to as axonal neuropathy after an adequate workup fails to determine a cause. A subgroup of patients with CIAP has impaired glucose tolerance (IGT). These patients have been considered by some investigators to have a neuropathy as a result of IGT and/or metabo...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2010.12.012
更新日期:2011-04-01 00:00:00
abstract::In literature, the cerebellum is given a substantial role in cognitive processes, in addition to traditional views on cerebellar function of regulating motor behaviour. The phenomenon of cerebellar damage causing impairments in memory and executive functioning was observed in various cerebellar disorders. Cerebellar c...
journal_title:Medical hypotheses
pub_type: 杂志文章,评审
doi:10.1016/j.mehy.2010.02.035
更新日期:2010-08-01 00:00:00
abstract::The reluctance of physicians to get involved with child abuse can be attributed to the problem of role conflict. Physicians derive their social authority from the Aesculapian tradition. This form of social authority is fragile and easily subverted, yet of utmost importance if physicians are to retain their effectivene...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(82)90028-7
更新日期:1982-04-01 00:00:00
abstract::Human immunodeficiency virus may regulate its replication by stimulating the synthesis of interleukin-1. Interleukin-1, in turn, has the ability to stimulate the human immunodeficiency virus enhancer region. The human genes responsible for interleukin-1 and interleukin-1 receptor antagonist synthesis are located on th...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(97)90040-2
更新日期:1997-05-01 00:00:00
abstract::We developed a new hypothesis claiming that natriuresis of fasting is not only caused by diminished insulin resistance and hyperinsulinaemia with the subsequent reduction of renal sodium retention but it can also be attributed to the function of the leptin-NPY system. Each element of this concept has been substantiate...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2000.1176
更新日期:2001-05-01 00:00:00
abstract::Cancer and other diseases may be a natural biological event, the activities of which may be dependent on the constitution of the individual. Where fetal and embryonic cells are not diseased or faulty or defective, they may be useful as therapies against cancer and other diseases. ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2001.1517
更新日期:2002-05-01 00:00:00
abstract::This paper outlines a method of demonstrating hepatitis B virus (HBV)-related transcriptional activity based on the random amplification of cDNA ends (RACE) protocol. Following RNA extraction from the appropriate tissue, cDNA is synthesized using a long oligo d(T) based primer containing unique 5' oligonucleotide sequ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(95)90056-x
更新日期:1995-08-01 00:00:00
abstract::Many studies have focused on the detrimental effects of malnourishment to the performance of the brain and peripheral nerves. Undernourished children and adults have been studied extensively to establish these consequences. Little attention has been given to the body habitus that affects optimum neurological performan...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.08.012
更新日期:2014-11-01 00:00:00
abstract::It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimicrobial resistance acqui...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(03)00205-6
更新日期:2003-10-01 00:00:00
abstract::A hypothesis is presented describing the operation of mammalian brains on the basis of rapid percussion chemical reactions and shock waves generated by such reactions. It is shown that the products of these are various chemical compounds identified as present in the brain. The manner in which the brain deals with vari...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(02)00296-7
更新日期:2002-12-01 00:00:00
abstract::Despite important advances in understanding its pathophysiology, therapy for septic shock remains largely symptomatic and supportive. Aiming to elevate the systemic arterial blood pressure by using vasoconstrictor manoeuvers are preferred without paying much attention to the ischaemia produced at the peripheral tissue...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2003.11.009
更新日期:2004-01-01 00:00:00