Abstract:
:Philadelphia chromosome (Ph1) positive, or "adult-type," chronic granulocytic leukemia (CGL) differs in many clinical and laboratory aspects from PH1-negative, or "juvenile," CGL. Because of these differences, the disorders have been considered two distinct disease entities. We present a child with Ph1-positive CGL whose disease has several features more characteristic of the Ph1-negative syndrome. This case demonstrates that the chromosomal anomaly in CGL is not always predictive of phenotypic expression in this disease.
journal_name
Am J Hematoljournal_title
American journal of hematologyauthors
Gay JC,Dessypris EN,Roloff JS,Lukens JNdoi
10.1002/ajh.2830160114subject
Has Abstractpub_date
1984-01-01 00:00:00pages
99-102issue
1eissn
0361-8609issn
1096-8652journal_volume
16pub_type
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journal_title:American journal of hematology
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journal_title:American journal of hematology
pub_type: 杂志文章
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journal_title:American journal of hematology
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doi:10.1002/ajh.2830290117
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journal_title:American journal of hematology
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