Pain assessment: differences in quality and intensity of the words pain, ache and hurt.

abstract：:This study critically examines the reported exercise-induced analgesia effect in view of the potential stress-induced analgesia of pain testing itself. Two designs were used to test whether previous findings of analgesia were induced by the exercise procedures or by the stress of the pain testing procedures themselves...

journal_title：Pain

authors： Padawer WJ,Levine FM

更新日期：1992-02-01 00:00:00

abstract：:A systematic review and meta-analysis of population-based epidemiological studies was undertaken to determine the prevalence of foot and ankle pain in middle and old age. Searches were conducted in the following electronic databases from inception to October 2010: PubMed, EMBASE, AMED, CINAHL, Cochrane, PEDro, and Spo...

journal_title：Pain

authors： Thomas MJ,Roddy E,Zhang W,Menz HB,Hannan MT,Peat GM

更新日期：2011-12-01 00:00:00

abstract：:Substance P (SP) is released from primary afferent fibers in response to nociceptive stimuli. Capsaicin, which produces an initial hyperalgesic response followed by persistent antinociception, also elicits release of SP from primary afferent fibers. Capsaicin pretreatment decreases the content and release of SP from p...

journal_title：Pain

authors： Goettl VM,Larson DL,Portoghese PS,Larson AA

更新日期：1997-07-01 00:00:00

abstract：:Currently, opioids targeting mu-opioid receptors are the most potent drugs for acute and cancer pain. However, opioids produce adverse side effects such as constipation, respiratory depression, or addiction potential. We recently developed (±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide (NFEPP), a co...

journal_title：Pain

authors： Massaly N,Temp J,Machelska H,Stein C

更新日期：2020-12-01 00:00:00

abstract：:Inflammation enhances release of neuropeptides from sensory nerve terminals in the spinal cord, and this may contribute to the development of hyperalgesia. In a similar manner, proinflammatory prostaglandins also augment peptide release from sensory neurons. To ascertain whether the inflammation-induced increase in pe...

journal_title：Pain

authors： Southall DM,Michael LR,Vasko RM

更新日期：1998-10-01 00:00:00

abstract：:Hydromorphone is an alternative to morphine for intrathecal drug delivery system to treat refractory cancer pain; however, there is not enough clinical evidence to prove it. In our study, 233 patients from 12 different pain management centers across China were enrolled, 121 and 112 in the intrathecal hydromorphone (IT...

journal_title：Pain

authors： Ma K,Jin Y,Wang L,Feng ZY,Song T,Yang XQ,Chen FQ,Duan BL,Huang YQ,Xie GL,Bao HG,Wang K,Xu JT,Lu Y,Liu YQ

更新日期：2020-11-01 00:00:00

abstract：:Chronic pain was induced in rats by daily injections of complete Freund's adjuvant into hind paws. Daily changes of pain threshold and endorphin (ED) content and their receptors in 4 divided parts: cortex, diencephalon-mesencephalon containing striatum (D-M), pons-medulla (P-M) and spinal cord, were measured. Decrease...

journal_title：Pain

authors： Yonehara N,Kudo T,Iwatsubo K,Maeda S,Saito K,Inoki R

更新日期：1983-09-01 00:00:00

abstract：:The neuropeptide bradykinin (BK) sensitizes nociceptor activation following its release in response to inflammatory injury. Thereafter, the bioactivity of bradykinin is controlled by the enzymatic activities of circulating peptidases. One such enzyme, the metalloendopeptidase EC3.4.24.15 (EP24.15), is co-expressed wit...

journal_title：Pain

authors： Gomez R,Por ED,Berg KA,Clarke WP,Glucksman MJ,Jeske NA

更新日期：2011-07-01 00:00:00

abstract：:A visual analog scale (VAS) method of assessing headache pain was compared with a standard categorical four-grade scale (4GS) in a randomized, placebo-controlled, double-blind, clinical trial involving 792 treated migraine outpatients who received oral rizatriptan 5 mg, sumatriptan 50 mg, or placebo for a moderate or ...

journal_title：Pain

authors： Lines CR,Vandormael K,Malbecq W

更新日期：2001-08-01 00:00:00

abstract：:We assessed nimodipine's ability to increase the analgesic effect of morphine in 32 patients suffering from cancer pain in a double-blind, placebo controlled cross-over study. Morphine administration began a few days before the start of the study. The analgesic effects of two combinations were compared: morphine (M) p...

journal_title：Pain

authors： Roca G,Aguilar JL,Gomar C,Mazo V,Costa J,Vidal F

更新日期：1996-12-01 00:00:00

abstract：:Existing estimates of sociodemographic disparities in chronic pain in the United States are based on cross-sectional data, often treat pain as a binary construct, and rarely test for nonresponse or other types of bias. This study uses 7 biennial waves of national data from the Health and Retirement Study (1998-2010; n...

journal_title：Pain

authors： Grol-Prokopczyk H

更新日期：2017-02-01 00:00:00

abstract：:To clarify the relationships between physical, and psychosocial components of chronic pain, a path analytic model was tested conceptualizing self efficacy as a mediator of disability. In turn, disability was hypothesized to mediate depression. This model could help explain the circumstances under which disability deve...

journal_title：Pain

authors： Arnstein P,Caudill M,Mandle CL,Norris A,Beasley R

更新日期：1999-04-01 00:00:00

abstract：:This study aimed to investigate the efficacy of an attention training technique (ATT) on pain ratings, threshold and tolerance during the cold pressor task. One hundred and three undergraduate students were randomly assigned to receive either threat-alleviating or threat-inducing information about the task. Participan...

journal_title：Pain

authors： Sharpe L,Perry NK,Rogers P,Dear BF,Nicholas MK,Refshauge K

更新日期：2010-09-01 00:00:00

abstract：:Chronic visceral pain affects millions of individuals worldwide and remains poorly understood, with current therapeutic options constrained by gastrointestinal adverse effects. Visceral pain is strongly associated with inflammation and distension of the gut. Here we report that the voltage-gated sodium channel subtype...

journal_title：Pain

authors： Hockley JR,Boundouki G,Cibert-Goton V,McGuire C,Yip PK,Chan C,Tranter M,Wood JN,Nassar MA,Blackshaw LA,Aziz Q,Michael GJ,Baker MD,Winchester WJ,Knowles CH,Bulmer DC

更新日期：2014-10-01 00:00:00

abstract：:Reports of pain during mammography show that there is great variability in both the incidence of reported pain (0.2-62%) and the intensity of that pain. Much of that variability may be due to the measures used to rate mammography pain. This is the first study that has examined the incidence, quality and intensity of m...

journal_title：Pain

authors： Kornguth PJ,Keefe FJ,Conaway MR

更新日期：1996-08-01 00:00:00

abstract：:A noxious cold stimulus can evoke multiple sensations each occurring with a different time course. We have performed psychophysical studies to identify the time course of five sensations evoked by a noxious cold stimulus applied to the hand. Subjects continuously rated either pain, ache, cold, heat or prickle sensatio...

journal_title：Pain

authors： Davis KD,Pope GE

更新日期：2002-07-01 00:00:00

abstract：:Patients with acute whiplash trauma were followed to examine if post-trauma ratings of pre-collision pain and psychological distress were associated with reduced work capability and neck pain at 12 months follow-up. The study included 740 consecutive patients (474 females, 266 males) referred from emergency department...

journal_title：Pain

authors： Carstensen TBW,Frostholm L,Oernboel E,Kongsted A,Kasch H,Jensen TS,Fink P

更新日期：2008-10-15 00:00:00

abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...

journal_title：Pain

authors： Roza C,Reeh PW

更新日期：2001-09-01 00:00:00

abstract：:The local anesthetic lidocaine was injected into the dentate gyrus (DG) of alert, unrestrained rats 10 min prior to investigation within the formalin test. Regional anesthesia of the DG resulted in a reduction of pain scores when administered contralateral to the site of subcutaneous formalin injection. The analgesic ...

journal_title：Pain

authors： McKenna JE,Melzack R

更新日期：1992-04-01 00:00:00

abstract：:The effect of the central grey matter (CG) on pain sensitivity has been investigated in rats. It has been demonstrated that baseline pain thresholds, tested by the hot plate method (HPM) after surgical operation, were significantly greater in CG-lesioned rats than in controls. Baseline tail flick latencies did not dif...

journal_title：Pain

authors： Bragin EO,Vasilenko GF,Durinjan RA

更新日期：1983-05-01 00:00:00

abstract：:The effects of nitrous oxide (N2O) are thought to be mediated by several pharmacological pathways at different levels of the central nervous system. Here, we focus on excitatory glutamatergic transmission in the superficial dorsal horn of the spinal cord with respect to its importance for the nociceptive processing. T...

journal_title：Pain

authors： Georgiev SK,Kohno T,Ikoma M,Yamakura T,Baba H

更新日期：2008-01-01 00:00:00

abstract：:The initial stages in the development of an Arabic pain inventory are described. 279 Kuwaiti adults were asked to nominate as many words as they could think of to describe pain. A dictionary translation of the McGill Pain Questionnaire (MPQ) was prepared, and subjects judged which of these represent acceptable pain de...

journal_title：Pain

authors： Harrison A

更新日期：1988-02-01 00:00:00

abstract：:Adrenal medullary transplants in the spinal subarachnoid space, by providing a continual source of opioid peptides and catecholamines, offer a potentially important adjunct in the management of chronic pain. While previous studies have shown that this approach is effective against high-intensity phasic stimuli, adrena...

journal_title：Pain

authors： Hama AT,Sagen J

更新日期：1993-02-01 00:00:00

abstract：:For many individuals undergoing routine surgical procedures, their satisfaction with the operation may depend upon their postoperative experience. We used the McGill Pain Questionnaire and the McGill Nausea Questionnaire to study the intensity of 5 common postoperative problems--sore throat, muscle pain, headache, bac...

journal_title：Pain

authors： Cohen MM,Tate RB

更新日期：1989-12-01 00:00:00

abstract：:This laboratory-based study examined lagged associations between child pain behavior and maternal responses as a function of maternal catastrophizing (CAT). Mothers completed the parent version of the Pain Catastrophizing Scale. Children participated in a validated water ingestion procedure to induce abdominal discomf...

journal_title：Pain

authors： Langer SL,Romano J,Brown JD,Nielson H,Ou B,Rauch C,Zullo L,Levy RL

更新日期：2017-09-01 00:00:00

abstract：:An 82-year-old woman experienced generalized pruritus not due to skin or systemic disease. Scratching the skin with a needle induced a crisis of intense pruritus, insensitive to any drug. The pruritus had the characteristics of a central sensation. ...

journal_title：Pain

authors： Procacci P,Maresca M

更新日期：1991-06-01 00:00:00

abstract：:Nerve growth factor (NGF) is known to produce hyperalgesia as well as to stimulate synthesis of neuropeptides in dorsal root ganglia (DRG). In the present study, we wanted to determine the effects of local NGF administration and assess to which extent mast cell-dependent factors are mediating NGF responses. Rats recei...

journal_title：Pain

authors： Amann R,Schuligoi R,Herzeg G,Donnerer J

更新日期：1996-02-01 00:00:00

abstract：:These experiments quantitatively analyzed effects of electrical midbrain stimulation on a nociceptive hind limb flexion reflex in rats anesthetized with sodium pentobarbital. We recorded the force of isometric hind limb flexion withdrawal, and related flexor electromyographic (EMG) activity, elicited by noxious heat (...

journal_title：Pain

authors： Carstens E,Campbell IG

更新日期：1988-05-01 00:00:00

abstract：:In the present study 366 patients suffering acute or chronic musculoskeletal pain of different origin were given vibratory stimulation for the pain. Many of the patients had previously had treatments of various kinds without satisfactory relief. The effect of vibratory stimulation was assessed during and after stimula...

journal_title：Pain

authors： Lundeberg T,Nordemar R,Ottoson D

更新日期：1984-09-01 00:00:00

abstract：:Intrusive pain is likely to have a serious impact on older people with limited ability to respond to additional stressors. Frailty is conceptualised as a functional and biological pattern of decline accumulating across multiple physiological systems, resulting in a decreased capacity to respond to additional stressors...

journal_title：Pain

authors： Blyth FM,Rochat S,Cumming RG,Creasey H,Handelsman DJ,Couteur DGL,Naganathan V,Sambrook PN,Seibel MJ,Waite LM

更新日期：2008-11-15 00:00:00