Sociodemographic disparities in chronic pain, based on 12-year longitudinal data.

Abstract:

:Existing estimates of sociodemographic disparities in chronic pain in the United States are based on cross-sectional data, often treat pain as a binary construct, and rarely test for nonresponse or other types of bias. This study uses 7 biennial waves of national data from the Health and Retirement Study (1998-2010; n = 19,776) to describe long-term pain disparities among older (age 51+) American adults. It also investigates whether pain severity, reporting heterogeneity, survey nonresponse, and/or mortality selection might bias estimates of social disparities in pain. In the process, the article clarifies whether 2 unexpected patterns observed cross-sectionally-plateauing of pain above age 60, and lower pain among racial/ethnic minorities-are genuine or artefactual. Findings show high prevalence of chronic pain: 27.3% at baseline, increasing to 36.6% thereafter. Multivariate latent growth curve models reveal extremely large disparities in pain by sex, education, and wealth, which manifest primarily as differences in intercept. Net of these variables, there is no racial/ethnic minority disadvantage in pain scores, and indeed a black advantage vis-à-vis whites. Pain levels are predictive of subsequent death, even a decade in the future. No evidence of pain-related survey attrition is found, but surveys not accounting for pain severity and reporting heterogeneity are likely to underestimate socioeconomic disparities in pain. The lack of minority disadvantage (net of socioeconomic status) appears genuine. However, the age-related plateauing of pain observed cross-sectionally is not replicated longitudinally, and seems partially attributable to mortality selection, as well as to rising pain levels by birth cohort.

journal_name

Pain

journal_title

Pain

authors

Grol-Prokopczyk H

doi

10.1097/j.pain.0000000000000762

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

313-322

issue

2

eissn

0304-3959

issn

1872-6623

pii

00006396-201702000-00016

journal_volume

158

pub_type

杂志文章

相关文献

PAIN文献大全
  • Substance dependence and chronic pain: profile of 50 patients treated in an alcohol and drug dependence unit.

    abstract::Fifty adult patients with chronic pain and substance dependence were admitted to an inpatient unit for treatment of addiction without primary emphasis on treatment of pain. As a group they had received considerable medical attention for their pain, but relatively little for their addictions. When compared with a group...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(86)90072-2

    authors: Finlayson RE,Maruta T,Morse RM,Swenson WM,Martin MA

    更新日期:1986-08-01 00:00:00

  • Tonic cholinergic inhibition of spinal mechanical transmission.

    abstract::The present study examined the role of spinal cholinergic modulation of spinal mechanical and thermal transmission. Intrathecal administration of the cholinergic muscarinic receptor antagonists atropine or scopolamine in awake rats produced a dose-dependent decrease in the nociceptive mechanical withdrawal threshold o...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(91)90078-C

    authors: Zhuo M,Gebhart GF

    更新日期:1991-08-01 00:00:00

  • Do we activate specifically somatosensory thin fibres with the concentric planar electrode? A scalp and intracranial EEG study.

    abstract::Laser-evoked potentials (LEPs) are acknowledged as the most reliable laboratory tool for assessing thermal and pain pathways. Electrical stimulation with a newly developed planar concentric electrode, delivering stimuli limited to the superficial skin layers, has been suggested to provide selective activation of Aδ fi...

    journal_title:Pain

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.pain.2012.03.004

    authors: Perchet C,Frot M,Charmarty A,Flores C,Mazza S,Magnin M,Garcia-Larrea L

    更新日期:2012-06-01 00:00:00

  • Comparison of cognitive-behavioral group treatment and an alternative non-psychological treatment for chronic low back pain.

    abstract::This study was designed to investigate the relative efficacy of cognitive-behavioral group treatment, including relaxation training, in comparison with a control condition in a sample of 20 outpatients with chronic low back pain. Subjects in both conditions also received the same physiotherapy back-education and exerc...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(92)90082-M

    authors: Nicholas MK,Wilson PH,Goyen J

    更新日期:1992-03-01 00:00:00

  • Brain networks predicting placebo analgesia in a clinical trial for chronic back pain.

    abstract::A fundamental question for placebo research is whether such responses are a predisposition, quantifiable by brain characteristics. We examine this issue in chronic back pain (CBP) patients who participated in a double-blind brain imaging (functional magnetic resonance imaging) clinical trial. We recently reported that...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2012.08.008

    authors: Hashmi JA,Baria AT,Baliki MN,Huang L,Schnitzer TJ,Apkarian VA

    更新日期:2012-12-01 00:00:00

  • An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain.

    abstract::Cannabinoids are emerging as potential options for neuropathic pain treatment. This study evaluated an oral cannabinoid, nabilone, in the treatment of refractory human diabetic peripheral neuropathic pain (DPN). We performed a single-center, randomized, double-blind, placebo-controlled, flexible-dose study with an enr...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2012.06.024

    authors: Toth C,Mawani S,Brady S,Chan C,Liu C,Mehina E,Garven A,Bestard J,Korngut L

    更新日期:2012-10-01 00:00:00

  • Orofacial pain onset predicts transition to head and neck cancer.

    abstract::Contrary to a clinical aphorism that early head and neck cancer is painless, we show that patients who develop head and neck cancer experience significant pain at the time of initial diagnosis. We compared orofacial pain sensitivity in groups of patients with normal oral mucosa, oral precancer, and newly diagnosed ora...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2011.02.009

    authors: Lam DK,Schmidt BL

    更新日期:2011-05-01 00:00:00

  • Intrathecal co-administration of substance P and NMDA augments nociceptive responses in the formalin test.

    abstract::The effects of intrathecal administration of substance P and N-methyl-D-aspartate (NMDA) were studied in the formalin test in mice. Both substances were administered 5 min before injection of formalin into the hind paw. Co-administration of substance P and NMDA intensified the response in both the 1st (0-10 min) and t...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(92)90260-I

    authors: Mjellem-Joly N,Lund A,Berge OG,Hole K

    更新日期:1992-11-01 00:00:00

  • Medullary on- and off-cell responses precede both segmental and thalamic responses to tail heating.

    abstract::Medullary on- and off-cell responses to tail heating were studied in lightly anesthetized rats. In 10 animals the electromyographic (EMG) activation of tail muscles was recorded simultaneously with on- or off-cells. The on-cell burst or the off-cell pause always preceded segmental EMG activation by about 0.5 sec. In t...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(89)90009-2

    authors: Hernández N,López Y,Vanegas H

    更新日期:1989-11-01 00:00:00

  • The self-efficacy of family caregivers for helping cancer patients manage pain at end-of-life.

    abstract::This preliminary study examined the self-efficacy of family caregivers with regard to helping cancer patients manage pain at end of life. A sample of 63 family caregivers of hospice-eligible cancer patients with pain provided ratings of their self-efficacy in assisting the patient in pain management and rated their ow...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/s0304-3959(02)00448-7

    authors: Keefe FJ,Ahles TA,Porter LS,Sutton LM,McBride CM,Pope MS,McKinstry ET,Furstenberg CP,Dalton J,Baucom DH

    更新日期:2003-05-01 00:00:00

  • Memory and pain: tests of mood congruity and state dependent learning in experimentally induced and clinical pain.

    abstract::The associative network theory of memory [2] is outlined along with the concepts of mood congruity and state dependent learning. Two experiments are reported which investigate the occurrence of these effects where memory for pain is concerned. In experiment 1 the performance of 25 chronic pain patients was compared wi...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(90)91072-Q

    authors: Pearce SA,Isherwood S,Hrouda D,Richardson PH,Erskine A,Skinner J

    更新日期:1990-11-01 00:00:00

  • Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve.

    abstract::The localization of sodium channels (NaChs) change following nerve lesions and this change may contribute to the development of increased pain states. Here we examine the change in distribution of NaChs within the rat infraorbital nerve (ION) two weeks after a combined inflammatory/partial axotomy lesion that results ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2006.05.028

    authors: Henry MA,Freking AR,Johnson LR,Levinson SR

    更新日期:2006-09-01 00:00:00

  • Polarised views on treating neurogenic pain.

    abstract::This study aimed to identify areas of disagreement in the management of neurogenic pain. A short questionnaire was mailed to 179 consultants with an interest in chronic pain (response rate 89%). The questionnaire listed 11 specific conditions involving nerve pain (e.g., post-herpetic neuralgia, causalgia) together wit...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(93)90035-N

    authors: Davies HTO,Crombie IK,Macrae WA

    更新日期:1993-09-01 00:00:00

  • Hypoalgesia elicited by a conditioned stimulus is blocked by a mu, but not a delta or a kappa, opioid antagonist injected into the rostral ventromedial medulla.

    abstract::The present study investigated the role of micro, delta, and kappa receptors within the RVM in mediating expression of conditional hypoalgesia (CHA). Five groups of rats with RVM cannulae were given daily sessions of paired or unpaired presentations of an auditory CS (white noise) and foot shock across three consecuti...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/S0304-3959(99)00125-6

    authors: Foo H,Helmstetter FJ

    更新日期:1999-12-01 00:00:00

  • Predictors of onset of facial pain and temporomandibular disorders in early adolescence.

    abstract::There are few prospective studies assessing risk factors for onset of temporomandibular (TMD) pain disorders in any age group. The aim of this prospective cohort study was to identify risk factors for onset of clinically significant TMD pain (i.e., pain meeting research diagnostic criteria for myofascial pain and/or a...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2006.10.012

    authors: LeResche L,Mancl LA,Drangsholt MT,Huang G,Von Korff M

    更新日期:2007-06-01 00:00:00

  • Effects of purinergic and adrenergic antagonists in a rat model of painful peripheral neuropathy.

    abstract::In previous studies, pain behaviors produced in the spinal nerve ligation rat model of neuropathic pain were partly reduced by surgical lumbar sympathectomy. However, systemic injection of phentolamine, an alpha-adrenoceptor blocker, was not effective in reducing pain behaviors, at least in the Sprague-Dawley strain o...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/S0304-3959(00)00277-3

    authors: Park SK,Chung K,Chung JM

    更新日期:2000-08-01 00:00:00

  • Dextromethorphan attenuates and reverses analgesic tolerance to morphine.

    abstract::Tolerance to the antinociceptive (analgesic) effect of morphine, a mu-opioid agonist, was developed in male CD-1 mice as assessed by a shift to the right of the analgesic (tail-flick) dose-response curves and an increase in the ED50 values. Administration of dextromethorphan at 30 mg/kg s.c., but not saline, 30 min pr...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(94)90022-1

    authors: Elliott K,Hynansky A,Inturrisi CE

    更新日期:1994-12-01 00:00:00

  • Nimodipine fails to enhance the analgesic effect of slow release morphine in the early phases of cancer pain treatment.

    abstract::We assessed nimodipine's ability to increase the analgesic effect of morphine in 32 patients suffering from cancer pain in a double-blind, placebo controlled cross-over study. Morphine administration began a few days before the start of the study. The analgesic effects of two combinations were compared: morphine (M) p...

    journal_title:Pain

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0304-3959(96)03186-7

    authors: Roca G,Aguilar JL,Gomar C,Mazo V,Costa J,Vidal F

    更新日期:1996-12-01 00:00:00

  • High-frequency stimulation in the ventral posterolateral thalamus reverses electrophysiologic changes and hyperalgesia in a rat model of peripheral neuropathic pain.

    abstract::Chronic neuropathic pain is associated with long-term changes at multiple levels of the neuroaxis, including in the brain, where electrical stimulation has been used to manage severe pain conditions. However, the clinical outcome of deep brain stimulation is often mixed, and the mechanisms are poorly understood. By me...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2011.07.011

    authors: Iwata M,LeBlanc BW,Kadasi LM,Zerah ML,Cosgrove RG,Saab CY

    更新日期:2011-11-01 00:00:00

  • Localized sympathectomy reduces peripheral nerve regeneration and pain behaviors in 2 rat neuropathic pain models.

    abstract::Previous studies have shown that the peripheral nerve regeneration process is linked to pain in several neuropathic pain models. Other studies show that sympathetic blockade may relieve pain in some pain models and clinical conditions. This study examined reduction in peripheral nerve regeneration as one possible mech...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001887

    authors: Xie W,Strong JA,Zhang JM

    更新日期:2020-08-01 00:00:00

  • Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain.

    abstract::Several studies have implicated a potential role for histamine H(3) receptors in pain processing, although the data are somewhat conflicting. In the present study we investigated the effects of the novel potent and highly selective H(3) receptor antagonists GSK189254 (6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepi...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2007.11.006

    authors: Medhurst SJ,Collins SD,Billinton A,Bingham S,Dalziel RG,Brass A,Roberts JC,Medhurst AD,Chessell IP

    更新日期:2008-08-15 00:00:00

  • Cerebral analgesic response to nonsteroidal anti-inflammatory drug ibuprofen.

    abstract::Nonopioid agents, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are the most commonly used class of analgesics. Increasing evidence suggests that cyclooxygenase (COX) inhibition at both peripheral and central sites can contribute to the antihyperalgesic effects of NSAIDs, with the predominant clinical effect ...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/j.pain.0000000000000176

    authors: Hodkinson DJ,Khawaja N,O'Daly O,Thacker MA,Zelaya FO,Wooldridge CL,Renton TF,Williams SCR,Howard MA

    更新日期:2015-07-01 00:00:00

  • Expression of 5-HT1A receptor mRNA in rat lumbar spinal dorsal horn neurons after peripheral inflammation.

    abstract::The present study observed the expression of the 5-hydroxytryptamine (5-HT) (1A) receptor mRNA in the lumbar spinal dorsal horn neurons following carrageenan inflammation using in situ hybridization (ISH). We also studied the co-localization of 5-HT(1A) receptor mRNA and gamma-amino butyric acid (GABA) or enkephalin (...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/S0304-3959(02)00026-X

    authors: Zhang YQ,Gao X,Ji GC,Huang YL,Wu GC,Zhao ZQ

    更新日期:2002-08-01 00:00:00

  • Decreased pain sensitivity among people with schizophrenia: a meta-analysis of experimental pain induction studies.

    abstract::Patients with schizophrenia report reduced pain sensitivity in clinical studies, but experimental studies are required to establish pain sensitivity as a potential endophenotype. We conducted a systematic review of electronic databases from database inception until April 15, 2015, including experimental studies invest...

    journal_title:Pain

    pub_type: 杂志文章,meta分析

    doi:10.1097/j.pain.0000000000000304

    authors: Stubbs B,Thompson T,Acaster S,Vancampfort D,Gaughran F,Correll CU

    更新日期:2015-11-01 00:00:00

  • Role of unilateral percutaneous cervical cordotomy in the treatment of neoplastic vertebral pain.

    abstract::The present study is a long-term report on 69 patients undergoing unilateral percutaneous cervical cordotomy for vertebral pain due to neoplastic bone metastases. The pain was unilateral or bilateral and was characterised by a chronic and/or an incident component. Seventy-one per cent (49/69) of the patients benefitte...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(84)90832-7

    authors: Ischia S,Luzzani A,Ischia A,Pacini L

    更新日期:1984-06-01 00:00:00

  • Thermal sensibility changes during ischemic nerve block.

    abstract::Changes in perception of pure thermal stimuli delivered to the hand at threshold intensity were observed during ischemic nerve block in 27 healthy subjects in order to study the significance of unmyelinated cutaneous cold receptors for thermal sensibility. Paresthesias and an increasing feeling of numbness were follow...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(84)90112-X

    authors: Fruhstorfer H

    更新日期:1984-12-01 00:00:00

  • Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch.

    abstract::Capsaicin-containing plant extracts have been used as topical treatments for a variety of pain syndromes for many centuries. Current products containing capsaicin in low concentrations (usually 0.025-0.075% w/w) have shown efficacy against a variety of pain conditions in clinical studies. However, in order to produce ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2004.07.017

    authors: Malmberg AB,Mizisin AP,Calcutt NA,von Stein T,Robbins WR,Bley KR

    更新日期:2004-10-01 00:00:00

  • Reference of pain following percutaneous cervical cordotomy.

    abstract::In order to clarify the mechanism of reference of pain following cordotomy (ROPC), the authors investigated ROPC in 66 patients undergoing percutaneous cervical cordotomy (PCC) and examined the features of ROPC and the correlation between the occurrence of ROPC and the pre-operative pain states, as well as the results...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(93)90082-Z

    authors: Nagaro T,Amakawa K,Kimura S,Arai T

    更新日期:1993-05-01 00:00:00

  • Dural afferents express acid-sensing ion channels: a role for decreased meningeal pH in migraine headache.

    abstract::Migraine headache is one of the most common neurological disorders. The pathological conditions that directly initiate afferent pain signaling are poorly understood. In trigeminal neurons retrogradely labeled from the cranial meninges, we have recorded pH-evoked currents using whole-cell patch-clamp electrophysiology....

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2010.09.036

    authors: Yan J,Edelmayer RM,Wei X,De Felice M,Porreca F,Dussor G

    更新日期:2011-01-01 00:00:00

  • Pain affect without pain sensation in a patient with a postcentral lesion.

    abstract::We report findings from clinical examination and cutaneous laser stimulation in a 57-year-old male, who suffered from a right-sided postcentral stroke. In this patient, we were able to demonstrate (i) a dissociation of discriminative and affective components of pain perception and, for the first time in humans, (ii) t...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/s0304-3959(99)00012-3

    authors: Ploner M,Freund HJ,Schnitzler A

    更新日期:1999-05-01 00:00:00