Isolation and nucleotide sequence determination of a gene encoding a heat-stable enterotoxin of Escherichia coli.

abstract：:Immune cytolysis was measured by release of absorbed radioactive chromium from infected cells that were incubated with antiviral antibody and complement. The presence of virus-specific antigens detected in this manner on the surface of several types of cells infected with Japanese encephalitis (JE) virus did not corre...

journal_title：Infection and immunity

authors： Brandt WE,Russell PK

更新日期：1975-02-01 00:00:00

abstract：:Actinobacillus actinomycetemcomitans is the etiologic agent of localized aggressive periodontitis, a rapidly progressing oral disease that occurs in adolescents. A. actinomycetemcomitans can also cause systemic disease, including infective endocarditis. In early work on A. actinomycetemcomitans workers concluded that ...

journal_title：Infection and immunity

authors： Balashova NV,Crosby JA,Al Ghofaily L,Kachlany SC

更新日期：2006-04-01 00:00:00

abstract：:Neisseria meningitidis is the causative agent of meningococcal disease. Onset of meningococcal disease can be extremely rapid and can kill within a matter of hours. However, although a much-feared pathogen, Neisseria meningitidis is frequently found in the nasopharyngeal mucosae of healthy carriers. The bacterial fact...

journal_title：Infection and immunity

authors： Ren X,MacKichan JK

更新日期：2014-12-01 00:00:00

abstract：:Previous studies have suggested that interleukin-4 (IL-4) has a protective effect in host defense to Borrelia burgdorferi infection, both in limiting the severity of arthritis and in controlling spirochete numbers in tissues, and a mapping study revealed suggestive linkage to a cluster of genes on mouse chromosome 11,...

journal_title：Infection and immunity

authors： Potter MR,Noben-Trauth N,Weis JH,Teuscher C,Weis JJ

更新日期：2000-10-01 00:00:00

abstract：:Susceptibility to Coccidioides spp. varies widely in humans and other mammals and also among individuals within a species. Among strains of mice with various susceptibilities, immunohistopathology revealed that C57BL/6 mice were highly susceptible to the disease following intranasal infection, DBA/2n mice were interme...

journal_title：Infection and immunity

authors： Shubitz LF,Dial SM,Perrill R,Casement R,Galgiani JN

更新日期：2008-12-01 00:00:00

abstract：:Gamma interferon (IFN-gamma)-primed human gingival fibroblasts (HGF) have been shown to produce higher levels of interleukin-8 (IL-8) upon stimulation with bacterial products and inflammatory cytokines than nonprimed controls. In this study, we examined whether priming of HGF with IFN-gamma up-regulates IL-8 productio...

journal_title：Infection and immunity

authors： Tamai R,Sakuta T,Matsushita K,Torii M,Takeuchi O,Akira S,Akashi S,Espevik T,Sugawara S,Takada H

更新日期：2002-03-01 00:00:00

abstract：:A cohort of 111 children from Bangui, Central African Republic, was surveyed for enteric Campylobacter infections from birth to the age of 2 years; stools were examined biweekly in these children until 6 months of age and at least four times per year thereafter until 2 years of age and after each diarrheal episode. Bl...

journal_title：Infection and immunity

authors： Martin PM,Mathiot J,Ipero J,Kirimat M,Georges AJ,Georges-Courbot MC

更新日期：1989-08-01 00:00:00

abstract：:Impaired erythropoiesis causes anemia during genetic disorders, chronic disease, and infection. In studies of the underlying mechanisms researchers have increasingly focused on gamma interferon (IFN-gamma). Here, we identified a previously unrecognized role for interleukin-15 (IL-15) in red blood cell homeostasis and ...

journal_title：Infection and immunity

authors： Mullarky IK,Szaba FM,Kummer LW,Wilhelm LB,Parent MA,Johnson LL,Smiley ST

更新日期：2007-05-01 00:00:00

abstract：:Piglets suckled by dams that had been vaccinated with K88 antigen were significantly more resistant to deaths caused by neonatal diarrhea after challenge with a large dose of a K88-positive enteropathogenic strain of Escherichia coli than piglets suckled by control dams. The factors most likely to be involved in prote...

journal_title：Infection and immunity

authors： Rutter JM,Jones GW,Brown GT,Burrows MR,Luther PD

更新日期：1976-03-01 00:00:00

abstract：:Microbial heat shock proteins (HSP) are dominant antigens for the host immune response. Because of the high sequence homology between mammalian and microbial HSP, their value as component of a subunit vaccine has been the subject of controversy. Previous work from this laboratory, however, demonstrated for the first t...

journal_title：Infection and immunity

authors： Noll A,AutenriethIB

更新日期：1996-08-01 00:00:00

abstract：:We developed an in vitro culture method to characterize the expression of bacterial genes under conditions mimicking the colonic environment. Our culture system (the intestinal simulator) comprised a continuous-flow anaerobic culture which was inoculated with fecal samples from healthy volunteers. As a test organism, ...

journal_title：Infection and immunity

authors： Ruiz-Perez F,Sheikh J,Davis S,Boedeker EC,Nataro JP

更新日期：2004-07-01 00:00:00

abstract：:The cell surface of Chlamydia psittaci seems important for establishing infection since (i) UV-treated elementary bodies (EB) attach to and are ingested by L cells and (ii) heat or antibody treatment decreases attachment to L cells and promotes the fusion of chlamydiae-containing phagosomes with lysosomes in macrophag...

journal_title：Infection and immunity

authors： Eissenberg LG,Wyrick PB,Davis CH,Rumpp JW

更新日期：1983-05-01 00:00:00

abstract：:A battery of lymphoid and nonlymphoid cells was examined for susceptibility to lysis by natural killer cells of chickens. Several susceptible targets were recognized, and most susceptible among these were cells of line LSCC-RP9, derived from a lymphoid tumor induced by Rous-associated virus 2. The natural killer react...

journal_title：Infection and immunity

authors： Sharma JM,Okazaki W

更新日期：1981-03-01 00:00:00

abstract：:To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the...

journal_title：Infection and immunity

authors： Pannekoek Y,van der Ende A,Eijk PP,van Marle J,de Witte MA,Ossewaarde JM,van den Brule AJ,Morré SA,Dankert J

更新日期：2001-07-01 00:00:00

abstract：:Nonviable Mycobacterium tuberculosis strain Jamaica suspended in oil-droplet emulsions was used to enhance resistance of mice against encephalomyocarditis virus (EMCV). The mycobacteria-injected mice were significantly resistant to 50,000 50% lethal doses of EMCV. Similar concentrations of virus in plasma of normal an...

journal_title：Infection and immunity

authors： Lodmell DL,Ewalt LC

更新日期：1978-12-01 00:00:00

abstract：:Streptococcus mutans Ingbritt was grown anaerobically in a chemostat, at a rate (mean generation time, 13 h) similar to that in dental plaque, in a complex medium with excess glucose and at pH values of 6.5, 6.0, and 5.5. The yield of cells was constant at pH 6.5 and 6.0 (2.00 mg/ml) but fell to 1.25 at pH 5.5; Y(gluc...

journal_title：Infection and immunity

authors： Hamilton IR,Ellwood DC

更新日期：1978-02-01 00:00:00

abstract：:To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spectrum of tuberculou...

journal_title：Infection and immunity

authors： Gong JH,Zhang M,Modlin RL,Linsley PS,Iyer D,Lin Y,Barnes PF

更新日期：1996-03-01 00:00:00

abstract：:Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of exp...

journal_title：Infection and immunity

authors： Ray TL,Payne CD

更新日期：1988-08-01 00:00:00

abstract：:A rapid and reproducible method of bacteriocin typing is described based on leakage of ultraviolet light-absorbing material (UVAM), detectable in supernatants of bacteriocin-sensitive cultures, by means of a spectrophotometer. The prerequisites for reproducible results, with nonsignificant fluctuations in standard err...

journal_title：Infection and immunity

authors： Farkas-Himsley H,Pagel A

更新日期：1977-04-01 00:00:00

abstract：:The typically recovered quantity of nontypeable Haemophilus influenzae (NTHi) bacteria in an ex vivo middle ear (ME) aspirate from the chinchilla model of experimental otitis media is insufficient for direct analysis of gene expression by microarray or of lipopolysaccharide glycoforms by mass spectrometry. This prompt...

journal_title：Infection and immunity

authors： Leroy M,Cabral H,Figueira M,Bouchet V,Huot H,Ram S,Pelton SI,Goldstein R

更新日期：2007-08-01 00:00:00

abstract：:Alpha-2,3-sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutively expressed from a single gene (lst) and does not undergo antigen...

journal_title：Infection and immunity

authors： Packiam M,Shell DM,Liu SV,Liu YB,McGee DJ,Srivastava R,Seal S,Rest RF

更新日期：2006-05-01 00:00:00

abstract：:Pneumolysin is a 471-amino-acid toxin produced by Streptococcus pneumoniae which has both cytolytic and complement activation properties. We have constructed a derivative of the type 2 S. pneumoniae strain D39 in which the portion of the pneumolysin gene encoding amino acids 55 to 437 has been deleted in-frame. The vi...

journal_title：Infection and immunity

authors： Berry AM,Ogunniyi AD,Miller DC,Paton JC

更新日期：1999-02-01 00:00:00

abstract：:The interaction of purified human fibrinogen with Aspergillus fumigatus conidia was investigated by immunofluorescence and electron microscopy and binding assays with radiolabeled proteins. We described the localization of the binding sites on the A. fumigatus conidia and on the fibrinogen molecule and determined the ...

journal_title：Infection and immunity

authors： Annaix V,Bouchara JP,Larcher G,Chabasse D,Tronchin G

更新日期：1992-05-01 00:00:00

abstract：:Lipooligosaccharide (LOS) is a major surface component of Moraxella catarrhalis and a possible virulence factor in the pathogenesis of human infections caused by this organism. The presence of LOS on the bacterium is an obstacle to the development of vaccines derived from whole cells or outer membrane components of th...

journal_title：Infection and immunity

authors： Peng D,Hong W,Choudhury BP,Carlson RW,Gu XX

更新日期：2005-11-01 00:00:00

abstract：:Vibrio parahaemolyticus is the leading cause of bacterial seafood-borne gastroenteritis worldwide, yet little is known about how this pathogen colonizes the human intestine. The alternative sigma factor RpoN/sigma-54 is a global regulator that controls flagellar synthesis, as well as a wide range of nonflagellar genes...

journal_title：Infection and immunity

authors： Whitaker WB,Richards GP,Boyd EF

更新日期：2014-02-01 00:00:00

abstract：:Burkholderia cenocepacia is an opportunistic pathogen that primarily infects cystic fibrosis (CF) patients. Previously, we reported that ShvR, a LysR regulator, influences colony morphology, virulence, and biofilm formation and regulates the expression of an adjacent 24-kb genomic region encoding 24 genes. In this stu...

journal_title：Infection and immunity

authors： Subramoni S,Nguyen DT,Sokol PA

更新日期：2011-08-01 00:00:00

abstract：:Ring-necked pheasant virus, an avian leukosis virus, when injected into 10-day old chick embryos, caused angiosarcomas in the lungs of infected chickens within a short time. Angiosarcomas appeared as localized foci of proliferating cells in the lungs as early as 2 weeks posthatch, and by 6 weeks, the lungs of the infe...

journal_title：Infection and immunity

authors： Carter JK,Proctor SJ,Smith RE

更新日期：1983-04-01 00:00:00

abstract：:We investigated the ability of interleukin 10 (IL-10) to protect mice against lethal shock induced by staphylococcal enterotoxin B (SEB). Treatment of mice with IL-10 prevented the death of mice injected with SEB in a dose-dependent manner. IL-10-mediated protection was apparent when administered either prior to or co...

journal_title：Infection and immunity

authors： Bean AG,Freiberg RA,Andrade S,Menon S,Zlotnik A

更新日期：1993-11-01 00:00:00

abstract：:Shiga toxin-producing Escherichia coli (STEC) is a food-borne pathogen with a low infectious dose that colonizes the colon in humans and can cause severe clinical manifestations such as hemolytic-uremic syndrome. The urease enzyme, encoded in the STEC chromosome, has been demonstrated to act as a virulence factor in o...

journal_title：Infection and immunity

authors： Steyert SR,Kaper JB

更新日期：2012-08-01 00:00:00

abstract：:Neisseria meningitidis is a major cause of sepsis and meningitis but is also a common commensal, present in the nasopharynx of between 8 and 20% of healthy individuals. During carriage, the bacterium is found on the surface of the nasopharyngeal epithelium and in deeper tissues, while to develop disease the meningococ...

journal_title：Infection and immunity

authors： Sutherland TC,Quattroni P,Exley RM,Tang CM

更新日期：2010-09-01 00:00:00