Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature.

Abstract:

:Two patients with plasma cell dyscrasias, manifested by osteosclerotic bone lesions and small amounts of M protein, and a complicating multi-system disorder are described. Their features of severe sensory-motor polyneuropathy, organomegaly, endocrine dysfunction, anasarca, elevated CSF protein, and skin hyperpigmentation are similar to a clinical syndrome reported primarily in Japanese men. Two previously unrecognized findings--hyperprolactinemia and an unusual radiographic abnormality of fluffy, spiculated bony proliferation--may facilitate recognition of the syndrome. The relationship of these various manifestations to the plasma cell dyscrasia is unknown, but a number of possibilities are discussed.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Bardwick PA,Zvaifler NJ,Gill GN,Newman D,Greenway GD,Resnick DL

doi

10.1097/00005792-198007000-00006

subject

Has Abstract

pub_date

1980-07-01 00:00:00

pages

311-22

issue

4

eissn

0025-7974

issn

1536-5964

journal_volume

59

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Rapid thrombelastography predicts perioperative massive blood transfusion in patients undergoing coronary artery bypass grafting: A retrospective study.

    abstract::Massive blood transfusion (MBT) is a relatively common complication of cardiac surgery, which is independently associated with severe postoperative adverse events. However, the value of using rapid thrombotomography (r-TEG) to predict MBT in perioperative period of cardiac surgery has not been explored. This study aim...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021833

    authors: Lin C,Fu Y,Huang S,Zhou S,Shen C

    更新日期:2020-09-11 00:00:00

  • Bevacizumab with preoperative chemotherapy versus preoperative chemotherapy alone for colorectal cancer liver metastases: a retrospective cohort study.

    abstract::This study aimed to assess the efficacy and safety of bevacizumab plus preoperative chemotherapy as first-line treatment for liver-only metastatic colorectal cancer in Chinese patients compared with those of preoperative chemotherapy alone.Patients with histologically confirmed liver-only metastatic colorectal cancer ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004767

    authors: Lu ZH,Peng JH,Wang FL,Yuan YF,Jiang W,Li YH,Wu XJ,Chen G,Ding PR,Li LR,Kong LH,Lin JZ,Zhang RX,Wan DS,Pan ZZ

    更新日期:2016-08-01 00:00:00

  • Universal antibiotic prophylaxis may no longer be necessary for patients with acute variceal bleeding: A retrospective observational study.

    abstract::A few decades ago, antibiotic prophylaxis for patients with acute variceal bleeding was reported beneficial. However, endoscopic and systemic therapy for variceal bleeding has dramatically improved since then, so the necessity of prophylactic antibiotics can be questioned. In this study, we reevaluated the efficacy of...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019981

    authors: Ueno M,Kayahara T,Sunami T,Takayama H,Takabatake H,Morimoto Y,Yamamoto H,Mizuno M

    更新日期:2020-05-01 00:00:00

  • Dorsal Penile Nerve Block With Ropivacaine-Reduced Postoperative Catheter-Related Bladder Discomfort in Male Patients After Emergence of General Anesthesia: A Prospective, Randomized, Controlled Study.

    abstract::Catheter-related bladder discomfort (CRBD) is a distressing symptom complex after surgery, especially in male patients who have had urinary catheterization under general anesthesia. In this prospective, randomized, controlled trial, we compared dorsal penile nerve block (DPNB) with 0.33% ropivacaine with intravenous t...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000003409

    authors: Li JY,Yi ML,Liao R

    更新日期:2016-04-01 00:00:00

  • Operative versus nonoperative treatment of displaced intra-articular calcaneal fractures: A meta-analysis of current evidence base.

    abstract:BACKGROUND:The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain. OBJECT:We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF. METHODS:Databases includ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000009027

    authors: Wei N,Yuwen P,Liu W,Zhu Y,Chang W,Feng C,Chen W

    更新日期:2017-12-01 00:00:00

  • 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in the diagnosis and follow-up of primary hepatic diffuse large B-cell Lymphoma: A clinical case report.

    abstract:RATIONALE:Primary hepatic lymphoma (PHL) is an extremely rare manifestation of extranodal non-Hodgkin lymphoma. There were few cases about PHL in recent years, while cases using positron emission tomography (PET) modalities for both diagnosis and follow-up were even rare. PATIENT CONCERNS:A 29-year-old man complaining...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018980

    authors: Wang L,Dong P,Hu W,Tian B

    更新日期:2020-01-01 00:00:00

  • Increased IgM-containing circulating immune complexes in patients co-infected with hepatitis C and hepatitis B.

    abstract::To assess the role of circulating immune complexes (CIC) in chronic hepatitis C virus (HCV) infection, the relative frequency of CIC was determined in 60 patients with chronic hepatitis C alone, 19 patients co-infected with hepatitis B and C, 15 asymptomatic HCV carriers, and 54 healthy controls. Levels of CIC were de...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-199505000-00003

    authors: Tsai JF,Jeng JE,Chang WY,Ho MS,Lin ZY,Tsai JH

    更新日期:1995-05-01 00:00:00

  • TACE plus percutaneous chemotherapy-lipiodol treatment of unresectable pedunculated hepatocellular carcinoma.

    abstract::Pedunculated hepatocellular carcinoma (P-HCC) is rare type of HCC. The study aimed to evaluate the clinical features and outcomes of unresectable P-HCC treated with transcatheter arterial chemoembolization (TACE) and percutaneous chemotherapeutic agents lipiodol emulsion (CALE) injection. The clinical features and out...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007650

    authors: Huang D,Chen Y,Chen S,Zeng Q,Zhao J,Wu R,Li Y

    更新日期:2017-07-01 00:00:00

  • Evaluation of the depiction ability of the microanatomy of the temporal bone in quarter-detector CT: Model-based iterative reconstruction vs hybrid iterative reconstruction.

    abstract::Little is known regarding differences between model-based iterative reconstruction (MBIR) and hybrid iterative reconstruction (HIR) in temporal bone computed tomography (CT). This study compared the ability to depict microstructures in temporal bone in quarter-detector CT (QDCT) between MBIR and HIR.Sixty-two temporal...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015991

    authors: Kurokawa R,Maeda E,Mori H,Amemiya S,Sato J,Ino K,Torigoe R,Abe O

    更新日期:2019-06-01 00:00:00

  • 99Tcm-MDP Imaging of Osteopetrosis: Case Report.

    abstract::Osteopetrosis, also known as marble bone disease, is a clinically rare genetic disease, which represents a heterogeneous group of rare, inherited bone dysplasias that share the hallmark of abnormally increased bone density caused by osteoclast dysfunction. Hereby, the authors describe a case of osteopetrosis that show...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000929

    authors: Zheng LC,OuYang XL,Liu GC,Zhang WJ,Zhang XM

    更新日期:2015-06-01 00:00:00

  • Proposed characterization of the syndrome of epidural pneumatosis (pneumorrhachis) in patients with forceful vomiting from diabetic ketoacidosis as a clinico-radiologic pentad based on systematic literature review & an illustrative case report.

    abstract:BACKGROUND:Previous literature on epidural pneumatosis (pneumorrhachis, or air in epidural cavity) associated with forceful vomiting in a patient with diabetic ketoacidosis (DKA) has consisted of individual case reports without comprehensive syndrome characterization due to syndromic rarity, with the largest previous l...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021001

    authors: Gill I,Edhi AI,Cappell MS

    更新日期:2020-08-28 00:00:00

  • Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke: A systematic review and meta-analysis.

    abstract:BACKGROUND:The receptor for advanced glycosylation end products (RAGE) has been widely linked to diabetic atherosclerosis, but its effects on coronary artery disease (CAD) and ischemic stroke (IS) remain controversial. The Gly82Ser polymorphism is located in the ligand-binding V domain of RAGE, suggesting a possible in...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000005593

    authors: Ma WQ,Qu QR,Zhao Y,Liu NF

    更新日期:2016-12-01 00:00:00

  • Systematic review and meta-analysis of the effect of probiotic supplementation on functional constipation in children.

    abstract:BACKGROUND:To evaluate the effect of probiotic supplementation on functional constipation in children. METHODS:We performed electronic searches in PubMed, Embase, and Cochrane Library without language restriction to identify relevant studies from the time of inception of these databases to March 2018. The relative ris...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000012174

    authors: Jin L,Deng L,Wu W,Wang Z,Shao W,Liu J

    更新日期:2018-09-01 00:00:00

  • Responses of smoking and nonsmoking cancer patients to drug treatment: A protocol for systematic review and meta-analysis.

    abstract:INTRODUCTION:Smoking is well-known to increase cancer risk, particularly risk of lung cancer, and negatively affects efficacy of cancer treatment. However, recent evidence suggests that among cancer patients, paradoxically, smokers respond to treatment better than non-smokers. We propose to conduct a focused review and...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022104

    authors: Wang L,Feng H,Li J,Liu F,Liu Q,Ji J,Postlethwaite A,Gu W,Shan B

    更新日期:2020-09-18 00:00:00

  • Direct reconstruction of chronic extensor digitorum longus tendon rupture using interposed scar tissue in the foot: A case report.

    abstract:RATIONALE:Primary repair of acute ligament injury is possible due to the proximity of the ends. In the case of chronic injury, however, primary repair is difficult because the ends of ruptured ligament will have receded, and tendon graft, transfer, or reconstruction is needed. Satisfactory clinical results have been re...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022506

    authors: Yeo ED,Han JK,Lee HS,Won SH,Jung KJ,Chang HJ,Cha JS,Ahn H,Lee DW,Kang JK,Kim WJ

    更新日期:2020-10-02 00:00:00

  • Low-Dose Versus Standard-Dose Tissue Plasminogen Activator in Acute Ischemic Stroke in Asian Populations: A Meta-Analysis.

    abstract::Recent studies have investigated the most efficacious dose of intravenous tissue plasminogen activator (IV-tPA) for acute ischemic stroke (AIS) patients. There remains no definitive consensus concerning the superior efficacious IV-tPA dose (standard- vs. low-dose), prompting us to perform a meta-analysis comparing the...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000002412

    authors: Liu MD,Ning WD,Wang RC,Chen W,Yang Y,Lin Y,Hu DH,Lau WB,Qu Y

    更新日期:2015-12-01 00:00:00

  • Erratum: Pelvic Fractures in Children Results from the German Pelvic Trauma Registry: A Cohort Study: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000002325.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000483155.73927.6c

    authors:

    更新日期:2016-05-06 00:00:00

  • Coreceptor usage of Chinese HIV-1 and impact of X4/DM transmission clusters among recently infected men who have sex with men.

    abstract::To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was p...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005017

    authors: Li X,Zhu K,Li W,Fang K,Musa TH,Song Y,Du G,Gao R,Guo Y,Yan W,Xuan Y,Zhong P,Wei P

    更新日期:2016-09-01 00:00:00

  • Fentanyl-based intravenous patient-controlled analgesia with low dose of ketamine is not inferior to thoracic epidural analgesia for acute post-thoracotomy pain following video-assisted thoracic surgery: A randomized controlled study.

    abstract:BACKGROUND:Thoracic epidural analgesia is the preferred method for postoperative analgesia following thoracic surgery. However, intravenous patient-controlled analgesia (IVPCA) may be an effective alternative. This study was conducted because few scientific reports exist comparing fentanyl-based IVPCA including a low d...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000016403

    authors: Tseng WC,Lin WL,Lai HC,Huang TW,Chen PH,Wu ZF

    更新日期:2019-07-01 00:00:00

  • Intramedullary cervical spinal cord teratoma.

    abstract:BACKGROUND:Intramedullary cervical spinal cord teratomas (ICTs) are extremely rare, and diagnosis and treatment are challenging. We conducted a systematic review of the literature on the diagnosis and treatment of ICT. METHOD:The presentation, imaging manifestations, diagnosis, management, surgery findings, prognosis ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020107

    authors: Wang L,Li T,Gong M,Xing F,Li L,Xiao R,Guan Q

    更新日期:2020-05-01 00:00:00

  • Therapeutic role of hyperinsulinemia/euglycemia in aluminum phosphide poisoning.

    abstract:BACKGROUND:Different protocols have been suggested to treat aluminum phosphide (ALP) poisoning. We aimed to evaluate the possible therapeutic effect of hyperinsulinemia/euglycemia (HIE) in treatment of ALP poisoning. METHODS:In a prospective interventional study, a total of 88 ALP-poisoned patients were included and a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004349

    authors: Hassanian-Moghaddam H,Zamani N

    更新日期:2016-08-01 00:00:00

  • Optical coherence tomographic analysis of drug-eluting in-stent restenosis at different times: A STROBE compliant study.

    abstract::The imaging characteristics of drug-eluting in-stent restenosis (ISR) at different times varied; however, the mechanism had not yet been elucidated.To analyze the imaging characteristics of drug-eluting ISR at different time points by optical coherence tomography (OCT) and investigate the cause of the stent treatment ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012117

    authors: Feng C,Zhang P,Han B,Li X,Liu Y,Niu D,Shi Y

    更新日期:2018-08-01 00:00:00

  • Diagnostic Ability of FDG-PET/CT in the Detection of Malignant Pleural Effusion.

    abstract::We investigated the role of F-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) for the differential diagnosis of malignant and benign pleural effusion. We studied 36 consecutive patients with histologically proven cancer (excluding malignant mesothelioma) who underwent FDG-PET/CT...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001010

    authors: Nakajima R,Abe K,Sakai S

    更新日期:2015-07-01 00:00:00

  • Multiple ectopic hepatocellular carcinomas in the pancreas: A case report.

    abstract:RATIONALE:Ectopic liver tissue can develop at various sites near the liver. Ectopic hepatocellular carcinomas (HCCs) arising from ectopic liver tissue have a rare clinical incidence. A very rare case has been observed to have metastasis after operation. PATIENT CONCERNS:We report an extremely rare case with multiple m...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006747

    authors: Li Z,Wu X,Wen T,Li C,Peng W

    更新日期:2017-07-01 00:00:00

  • Cetuximab concurrent with IMRT versus cisplatin concurrent with IMRT in locally advanced nasopharyngeal carcinoma: A retrospective matched case-control study.

    abstract::To evaluate the treatment efficacies and toxicities of concurrent cetuximab-based bioradiotherapy (BRT) or cisplatin-based chemoradiotherapy (CRT) in locally advanced nasopharyngeal carcinoma. :Patients with previously untreated locally advanced nasopharyngeal carcinoma were matched into pairs, and enrolled into the s...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004926

    authors: Wu X,Huang J,Liu L,Li H,Li P,Zhang J,Xie L

    更新日期:2016-09-01 00:00:00

  • Mild encephalopathy with a reversible splenial lesion mimicking transient ischemic attack: A case report.

    abstract:BACKGROUND:Reversible splenial lesion syndrome (RESLES) is a newly recognized syndrome, and a reversible progress associated with transiently reduced diffusion lesion in the splenium of the corpus callosum (SCC) is the typical pathological finding. The routine clinical symptoms include mildly altered states of consciou...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005258

    authors: Dong K,Zhang Q,Ding J,Ren L,Zhang Z,Wu L,Feng W,Song H

    更新日期:2016-11-01 00:00:00

  • Copy number variations of neurotrophic tyrosine receptor kinase 3 (NTRK3) may predict prognosis of ovarian cancer.

    abstract::Platinum resistance is a critical barrier for clinicians to improve the survival of ovarian cancer. Our study evaluated the correlation between copy number variations (CNVs) of neurotrophic tyrosine receptor kinase 3 (NTRK3) and the prognosis of ovarian cancer, which might predict platinum resistance in ovarian cancer...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007621

    authors: Ge L,Li N,Liu M,Xu NZ,Wang MR,Wu LY

    更新日期:2017-07-01 00:00:00

  • Comorbidities, risk, and socioeconomic factors of uninsured cancer survivors.

    abstract::Cancer patients can be well-connected to resources during treatment but become lost to follow-up and subsequently may receive treatment in free clinics for chronic morbidities. Few studies have examined outcomes for uninsured patients with cancer histories in free clinics, but research examining socioeconomic determin...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013121

    authors: Mirza AS,Pabbathi S,Lu Y,Ayoubi N,Ewing A,Jaglal M,Roetzheim R

    更新日期:2018-11-01 00:00:00

  • Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studies.

    abstract::In a retrospective review of 53 patients, 58 episodes of infection due to Acinetobacter calcoaceticus var. anitratus (Herellea vaginicola) were studied. Although the organism is widely distributed in nature, it is of relatively low virulence since colonization is more frequently noted than infection and since most inf...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-197703000-00001

    authors: Glew RH,Moellering RC Jr,Kunz LJ

    更新日期:1977-03-01 00:00:00

  • Opioid analgesics are the leading cause of adverse drug reactions in the obstetric population in South Korea.

    abstract::Medication use during pregnancy is gradually increasing; however, the safety of this practice remains largely unknown.We investigated medications with the most adverse drug reactions (ADRs) among pregnant women and the clinical features of those medications.Reports of ADRs among pregnant women were extracted from the ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015756

    authors: Choi SK,Kim YH,Kim SM,Wie JH,Lee DG,Kwon JY,Song JH,Lee SJ,Park IY

    更新日期:2019-05-01 00:00:00