Abstract:
:Catheter-related bladder discomfort (CRBD) is a distressing symptom complex after surgery, especially in male patients who have had urinary catheterization under general anesthesia. In this prospective, randomized, controlled trial, we compared dorsal penile nerve block (DPNB) with 0.33% ropivacaine with intravenous tramadol 1.5 mg kg(-1) in prevention of CRBD, as well as the incidences of postoperative side effects. Fifty-eight male patients aged 18 to 50 years, undergoing elective liver surgery and limb surgery with urinary catheterization, were enrolled and divided randomly into 2 groups. In the DPNB group, patients were given dorsal penile nerve block with 15 mL of 0.33% ropivacaine, and in the tramadol intravenous administration (TRAM) group, patients were given 1.5 mg kg(-1) tramadol after the completion of surgery before extubation. The primary outcome was the incidence of CRBD, and the secondary outcomes included the severity of CRBD, postoperative side effects, postoperative pain, and the acceptance of urinary catheterization. Patients were evaluated upon arrival to postanesthetic care unit (PACU), at 0.5, 1, 2, 4, and 6 hours after patients' arrival in the PACU for outcomes. The incidence of CRBD was significantly lower in the DPNB group than in the TRAM group, either upon arrival to PACU (10.3% vs 37.9%, P = 0.015), or at 0.5 hours (3.4% vs 34.5%, P = 0.003), 1 hours (3.4% vs 37.9%, P = 0.001), 2 hours (6.9% vs 34.5%, P = 0.010), and 4 hours (6.9% vs 27.6%, P = 0.039) after patients' arrival in PACU. Compared with the TRAM group, the severity of postoperative CRBD upon arrival to PACU (P = 0.011) and at 0.5 hours (P = 0.005), 1 hours (P = 0.002), 2 hours (P = 0.005), 4 hours (P = 0.017), and 6 hours (P = 0.047) after patients' arrival in PACU were all significantly reduced in the DPNB group. The incidences of postoperative nausea, vomiting, dizziness, and sedation were decreased significantly in the DPNB group compared with the TRAM group (P < 0.05). The acceptance of urinary catheterization was 93.1% (27/29 patients) in the DPNB group and 58.6% (17/29 patients) in the TRAM group, respectively (P < 0.001).DPNB with ropivacaine has a better effect for CRBD reduction and less side effects than intravenous tramadol administration. The trial has been registered at www.clinicaltrials.gov (NCT01721031).
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Li JY,Yi ML,Liao Rdoi
10.1097/MD.0000000000003409subject
Has Abstractpub_date
2016-04-01 00:00:00pages
e3409issue
15eissn
0025-7974issn
1536-5964pii
00005792-201604120-00083journal_volume
95pub_type
杂志文章,随机对照试验相关文献
MEDICINE文献大全abstract::The purpose of this study was to determine the risk stratification of deep venous thrombosis (DVT) in patients undergoing gynecological surgery. A retrospective study was conducted with a cohort of 739 consecutive female patients undergoing gynecological surgery between May 2008 and July 2013 in Beijing Chao-yang hosp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001653
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Allergic rhinitis is a major chronic inflammatory disease of the respiratory tract. A large number of epidemiological investigations have shown that the prevalence of allergic rhinitis (AR) is increasing, resulting in a large burden of disease. Desensitizing drugs such as nasal glucocorticoids and antihistam...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013772
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Oropharyngeal mucositis is considered to be an inevitable and the most troubling side effect of head and neck irradiation, which is caused by the direct toxic action of radiation on oral mucosa. Several randomized controlled trials (RCTs) have investigated the efficacy of zinc sulfate in prevention of radiat...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013310
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Previous literature on epidural pneumatosis (pneumorrhachis, or air in epidural cavity) associated with forceful vomiting in a patient with diabetic ketoacidosis (DKA) has consisted of individual case reports without comprehensive syndrome characterization due to syndromic rarity, with the largest previous l...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021001
更新日期:2020-08-28 00:00:00
abstract:RATIONALE:Parvovirus B19 has been linked to polyarteritis nodosa (PAN), but there is some controversy about its pathogenesis regarding whether it is triggered by the immune complex or by the activated immune cells that phagocytose viruses. PATIENT CONCERNS:A 38-year-old woman was admitted with fever and bicytopenia. S...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022079
更新日期:2020-09-04 00:00:00
abstract::The first case of atypical pneumonia caused by coronavirus disease 2019 (COVID-19) was reported in Wuhan, China in December 2019. Since then, cases of novel coronavirus-infected pneumonia (NCIP) have been reported throughout China as well as in 25 other countries. With the rapid growth of this global outbreak, psychol...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021662
更新日期:2020-08-21 00:00:00
abstract::To establish a clinical prediction rule for acute bilirubin encephalopathy (ABE) in term/near-term neonates with extreme hyperbilirubinemia.A retrospective cohort study was conducted between January 2015 and December 2018. Six hundred seventy-three out of 26,369 consecutive neonates with extreme hyperbilirubinemia wer...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019364
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION:Accessory liver lobe (ALL), an autonomous island of normal liver parenchyma, is a rare congenital anomaly that is difficult for preoperative diagnosis and often identified incidentally. It can also be accompanied with benign or malignant diseases, which is extremely rare. There are only 3 cases of focal no...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000021357
更新日期:2020-07-24 00:00:00
abstract::Although it is an invasive and unpleasant procedure, esophagogastroduodenoscopy (EGD) is still the gold standard for esophageal varices (EV) detection. The aim of this study was to investigate liver stiffness measurement (LSM) and spleen diameter as simple noninvasive tools for EV prediction in chronic hepatitis C pat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008621
更新日期:2017-11-01 00:00:00
abstract::The role of cancer stem cell (CSC) markers in differentiation of hepatocellular carcinoma (HCC) remains uncertain. We conducted a meta-analysis to first investigate the association between expression of CSC markers (CD133, CD90, CD44, and EpCAM) and poor differentiation of HCC, and second, to determine if these CSC ma...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000001306
更新日期:2015-08-01 00:00:00
abstract::Twenty-three patients with systemic lupus erythematosus (SLE) and ischemic bone necrosis are reported. All patients had received corticosteroids prior to the onset of ischemic necrosis, although one patient had received none for 13 years previously. Nineteen (83%) patients had multiple bone lesions including the femor...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-197605000-00004
更新日期:1976-05-01 00:00:00
abstract:RATIONALE:Hemophagocytic lymphohistiocytosis (HLH) secondary to methicillin-resistant Staphylococcus epidermidis (MRSE)-related left-sided infectious endocarditis had never been reported before. In the last decade, daptomycin, a novel lipopeptide antibiotic, showed its excellent role in anti-Gram-positive bacteria, inc...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000009451
更新日期:2017-12-01 00:00:00
abstract::It is important to estimate motor recovery in the early phase after stroke. Many studies have demonstrated that both diffusion tensor tractography (DTT) and motor-evoked potentials (MEP) are valuable predictors of motor recovery, but these modalities do not directly reflect the status of the injured gray matter. We re...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003838
更新日期:2016-06-01 00:00:00
abstract::The features of herpes zoster share some commonalities with depression, including decreased cellular immunity, a close correlation with nutritional status, and a higher prevalence in the elderly population. We aimed to assess the association between herpes zoster infection and depression in the Korean population.We pe...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017430
更新日期:2019-10-01 00:00:00
abstract:RATIONALE:Acute appendicitis is one of the most common causes of acute abdomen in children, yet it is difficult to diagnose in young children because its clinical manifestations may be atypical. Here, 3 atypical clinical cases associated with appendicitis in children are reported. PATIENT CONCERN:The 1st case correspo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015006
更新日期:2019-03-01 00:00:00
abstract::Genetic etiology hypothesis is widely accepted in the development of congenital scoliosis (CS). The delta-like 3 (DLL3) gene, a member of the Notch signaling pathway, was implicated to contribute to human CS. In this study, a case-control association study was conducted to determine the association of single nucleotid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004347
更新日期:2016-07-01 00:00:00
abstract::Short Synacthen test (SST) involves measuring the baseline, 30-, and 60-minute serum cortisol levels, after injecting 250 μg of synthetic adrenocorticotropic hormone or Synacthen (ACTH). This study aimed to review the current clinical practice of performing SST to establish a standardized test protocol and to addition...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022621
更新日期:2020-10-23 00:00:00
abstract::The aim of this study was to compare bone mineral densities (BMDs) and body composition between Southeast Asia college students and Chinese college students, in order to provide a certain reference enhancing college students' physical fitness.A total of 1694 Chinese college students (294 men and 1400 women, aged 18-22...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004724
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Chronic liver disease is traditionally conceived as a risk factor for cardiovascular surgery. Transcatheter aortic valve implantation (TAVI) has recently burgeoned to precede surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis at intermediate to high surgical risk. The evidence r...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000019766
更新日期:2020-04-01 00:00:00
abstract:RATIONALE:Capecitabine (CAP) is a chemotherapeutic agent used to treat breast and gastrointestinal cancers. The most common adverse reactions of CAP primarily included gastrointestinal and dermatological effects. Whereas, the CAP-induced fatty liver had never been reported. PATIENT CONCERNS:In this study, a-69-year ol...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008547
更新日期:2017-11-01 00:00:00
abstract::Thyrotoxic periodic paralysis (TPP) is characterized by the presence of muscle paralysis, hypokalemia, and hyperthyroidism. We report the case of a young man with paralysis of the lower extremities, severe hypokalemia, and concurrent hyperthyroidism. TPP was suspected; therefore, treatment consisting of judicious pota...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001689
更新日期:2015-09-01 00:00:00
abstract:RATIONALE:Germinomas are sensitive to radiation therapy and chemotherapy; therefore, correct imaging diagnosis is crucial for them. However, the imaging findings of germinomas originating from off-midline regions displayed different patterns from those originating from midline areas. PATIENT CONCERNS:The objective of ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000005543
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Many reports suggest that aldehyde dehydrogenase 1 (ALDH1) expression is associated with poorer neoadjuvant chemotherapy (NAC) response in patients with breast cancer; however, the prognostic value of this enzyme in cancer has yet to be confirmed. Therefore, we conducted a meta-analysis of related studies to...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000012056
更新日期:2018-08-01 00:00:00
abstract:RATIONALE:Angiosarcoma is an extremely rare malignant tumor of endothelial origin. The majority of studies reporting angiosarcoma have been concerned with the clinical and pathological aspects, with limited reporting of their imaging findings. To our knowledge, angiosarcoma of the adrenal gland is very rare. Herein we ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008551
更新日期:2017-11-01 00:00:00
abstract::Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000465
更新日期:2015-01-01 00:00:00
abstract::Nuclear factor-κB-inducing kinase (NIK) is a new regulator of nuclear factor-κB signaling, which plays an important role in tumorigenesis. This study aimed to examine the expression of NIK in gastric cancer and investigate its clinical significance.Tumor issues were collected from 80 gastric cancer patients who receiv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018864
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Colorectal cancer was a complex disease with multiple causative factors including genetic and environmental factors, as well as the interaction of the 2 factors. Relationship between epidermal growth factor (EGF) A61G polymorphism and colorectal cancer risk has been widely investigated previously, whereas re...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014007
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Canagliflozin is a new SGLT2 inhibitor which has been approved as an adjunct to diet and exercise for the treatment of adults with type 2 diabetes (T2D) mellitus in more than 30 countries. To evaluate the efficacy and safety of canagliflozin in patients with T2D, we carried out a meta-analysis of phase III c...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000005473
更新日期:2016-11-01 00:00:00
abstract::The aim of this study was to evaluate the effect of prenatal and postnatal malnutrition on the intellectual functioning of early school-aged children. We followed the offspring of women who had participated in a trial of prenatal supplementation with different combinations of micronutrients and who remained resident i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004161
更新日期:2016-08-01 00:00:00
abstract::Churg-Strauss Syndrome (CSS) complicated with cardiogenic shock is rare. Few case reports have described successful treatment of this rare disease. However, no one has reported on the application of mechanical life support with extracorporeal membrane oxygenation (ECMO) to treat this life-threatening disease.A 36-year...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001757
更新日期:2015-10-01 00:00:00