Abstract:
BACKGROUND:Thoracic epidural analgesia is the preferred method for postoperative analgesia following thoracic surgery. However, intravenous patient-controlled analgesia (IVPCA) may be an effective alternative. This study was conducted because few scientific reports exist comparing fentanyl-based IVPCA including a low dose of ketamine (fk-IVPCA) with thoracic patient-controlled epidural analgesia (t-PCEA) for the treatment of postoperative pain after video-assisted thoracic surgery (VATS). METHODS:This prospective, and randomized study included 70 patients randomized into fk-IVPCA and t-PCEA groups. Pain at rest and during movement, successful and unsuccessful triggers after pressing the PCA device button, the need for rescue analgesia, drug-related adverse events, and patient satisfaction were recorded for 48 hours postoperatively. RESULTS:No significant differences in the intensity of pain at rest or during movement were observed between the 2 groups within 48 hours postoperatively. The number of unsuccessful PCA triggers in the t-PCEA group 0 to 4 hours after surgery was significantly higher than that in the fk-IVPCA group. However, the numbers of successful PCA triggers in the fk-IVPCA group at 4 to 12 and 0 to 24 hours after surgery were significantly higher than those in the t-PCEA group. The incidence of analgesic-related side effects and patient satisfaction were similar in both groups. CONCLUSIONS:Compared with t-PCEA, the addition of a subanesthetic dose of ketamine to fentanyl-based IVPCA resulted in similar pain control after VATS with no increase in the incidence of drug-related adverse effects. The results confirm that both multimodal intravenous analgesia and epidural analgesia can provide sufficient pain control and are safe strategies for treating acute post-thoracotomy pain.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Tseng WC,Lin WL,Lai HC,Huang TW,Chen PH,Wu ZFdoi
10.1097/MD.0000000000016403subject
Has Abstractpub_date
2019-07-01 00:00:00pages
e16403issue
28eissn
0025-7974issn
1536-5964pii
00005792-201907120-00063journal_volume
98pub_type
杂志文章,随机对照试验相关文献
MEDICINE文献大全abstract:RATIONALE:Myoepithelial carcinoma mainly occurs in the salivary glands, but myoepithelial carcinoma of the lung is extremely rare neoplasm whose biological behavior and clinical course still remain to be fully elucidated. Although considered as low-grade carcinoma, these tumors have a high rate of recurrence or distant...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000010049
更新日期:2018-03-01 00:00:00
abstract::The aim of the study was to investigate current situation of postoperative pain management in medical institutions in Shandong Province.A questionnaire was developed on the basis of guidelines of acute pain and pain quality assessment scale. The questionnaire was used to obtain information regarding the nature and sca...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002690
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Drug intensification is often required for patients with type 2 diabetes mellitus on stable metformin therapy. Among the potential candidates for a combination therapy, sodium-glucose transporter-2 (SGLT2) inhibitors have shown promising outcomes. This meta-analysis was performed to compare the efficacy and ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000007201
更新日期:2017-07-01 00:00:00
abstract::Ovarian cancer is one of the common female malignant tumors. The early diagnosis and treatment of ovarian cancer has been a research hotspot. Therefore, we aimed to investigate the correlations between the levels of carbohydrate antigen 125 (CA125), human epididymis protein 4 (HE4), D-dimer (DDI), and fibrinogen degra...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023329
更新日期:2020-12-04 00:00:00
abstract:RATIONALE:Pancreaticopleural and pancreaticomediastinal fistulas are rare complications of pancreatitis. They are often misdiagnosed and there are no strict guidelines of treatment. In this study, we present a brief report of a combined pancreaticopleural and pancreaticomediastinal fistula extending to the cervical reg...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014233
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The top-cited systematic reviews/meta-analyses in tuberculosis research have not been identified. The objective of this study was to identify the 100 top-cited systematic reviews/meta-analyses in tuberculosis research, and to understand factors resulting in highly cited works, and establish trends in systema...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004822
更新日期:2017-02-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000003413.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000484496.43819.1a
更新日期:2016-08-19 00:00:00
abstract::The cerebellum has been proven to be connected to the brain network, as in the default-mode network (DMN), among healthy subjects and patients with psychiatric disorders. However, whether or not abnormal cerebellar DMN connectivity exists and what its clinical significance is among drug-naive patients with somatizatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004043
更新日期:2016-07-01 00:00:00
abstract:RATIONALE:Acinar cell carcinomas (ACCs) and mixed acinar-endocrine carcinomas (MAECs) of the pancreas are rare, accounting for only 1% of pancreatic tumors. Although both typically present at an advanced stage, chemotherapeutic regimes have not yet been standardized. PATIENT CONCERNS:A 65-year-old man presented with a...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008534
更新日期:2017-11-01 00:00:00
abstract::Irreversible electroporation (IRE) is a new nonthermal tumor ablation modality that induces apoptosis in the treated tissue without affecting collagen. Its use is particularly indicated for tumors involving major structures, such as encompassed or infiltrated vessels and/or ducts, which need to be preserved and hinder...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000946
更新日期:2015-07-01 00:00:00
abstract::As detection rates of non-albicans Candida species are increasing, determining their pathogen profiles and antifungal susceptibilities is important for antifungal treatment selection. We identified the antifungal susceptibility patterns and predictive factors for mortality in candidemia.A multicenter retrospective ana...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000019494
更新日期:2020-03-01 00:00:00
abstract::The aim of study is to determine whether chronic osteomyelitis (COM) is linked to an increased risk of head and neck cancer (HNC).We identify 17,033 patients with osteomyelitis and 68,125 subjects without osteomyelitis during 1996 to 2010 periods. Multivariable Cox proportional hazards regression analysis was used to ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002407
更新日期:2016-01-01 00:00:00
abstract::Obstructive sleep apnea (OSA) has a high prevalence in patients with obesity. Only patients with clinical symptoms of OSA are admitted to polysomnography; however, many patients with OSA are asymptomatic. We aimed to create and validate a population-based risk score that predicts the severity of OSA in patients with o...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016687
更新日期:2019-08-01 00:00:00
abstract::Few studies have yet investigated the possible association between high-density lipoprotein cholesterol (HDL-C) and kidney function in elderly patients with primary hypertension. Accordingly, the aim of the present study was to evaluate the relationship between HDL-C and kidney function in elderly hypertension. A tota...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000651
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:This study aimed to investigate the safety and efficacy of the cystotome-assisted prechop phacoemulsification surgery (CAPPS) and conventional phacoemulsification surgery (CPS) in patients with IV degree nucleus cataract. METHODS:The prospective, randomized, consecutive, comparative cohort study consecutive...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000013124
更新日期:2018-11-01 00:00:00
abstract::The aim of this study was to elucidate the possible association between migration inhibitory factor (MIF)-173G/C gene polymorphisms and transcript and plasma levels of MIF in spinal tuberculosis (TB) patients. Clinical data were collected from 254 spinal TB patients and 262 healthy controls participating in the study....
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021331
更新日期:2020-07-24 00:00:00
abstract:RATIONALE:With the progress of sequencing technology, an increasing number of atypical primary immunodeficiency (PID) patients have been discovered, including Janus kinase 3 (JAK3) gene deficiency. PATIENT CONCERNS:We report a patient who presented with chronic active Epstein-Barr virus (CAEBV) infection but responded...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000007989
更新日期:2017-10-01 00:00:00
abstract::This study aimed to detail the clinical outcomes of patients suffering from celiac arterial aneurysm (CAA) that underwent treatment via stent occlusion.This is a single-center, retrospective study. A total of 8 consecutive CAA patients were treated via stent occlusion from March 2014 to September 2018 at our hospital....
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023448
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Rotavirus (RV) can cause vomiting and diarrhea in infants and children, and could be treated clinically with immunoglobulin Y (IgY), which is an immunoglobulin extracted from chicken yolk. There is no systematic evaluation of immunoglobulin in the treatment of rotavirus enteritis. Therefore, we systematicall...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016100
更新日期:2019-07-01 00:00:00
abstract::Cerebral microbleeds (CMBs) and lacunar infarcts are common manifestations of cerebral small vessel disease. However, the association between the location of CMBs and lacunar infarcts is unclear. Our study aimed to clarify the relationship between the location of CMBs and lacunar infarcts.This study retrospectively an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011031
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The role of real-time elastography (RTE)-targeted biopsy in the detection and diagnosis of prostate cancer (PCa) remains controversial. METHODS:We searched Medline, Embase, and Cochrane Library from inception to July 31, 2017 and used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000010220
更新日期:2018-03-01 00:00:00
abstract::The surgical treatment of congenital scoliosis under 10 years is difficult as it involves resecting vertebrae. Moreover, patient follow-up after surgery is extremely important because the patient is a child whose growth has not been completed. However, there are very few long-term follow-up studies after surgical trea...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021720
更新日期:2020-08-07 00:00:00
abstract::To investigate the molecular mechanisms of later metabolic health changes in large for gestational age (LGA) newborns by analyzing deoxyribonucleic acid (DNA) methylation patterns in the placenta of LGA and appropriate for gestational age (AGA) newborns.A total of 6 placentas of LGA and 6 placentas of AGA newborns wer...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022389
更新日期:2020-09-25 00:00:00
abstract:RATIONALE:Treprostinil, a potent vasodilator, is the treatment of choice for severe pulmonary arterial hypertension (PAH) during pregnancy. Its inhibition of platelet aggregation increases the risk of hemorrhage. In addition, anticoagulation therapy is widely used in pregnancy with PAH due to the hypercoagulable state....
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011810
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). METHODS:PubMed, EMBASE, Springer LINK, Cochrane Library, the China National Knowledge Infrastructure, Chongqing Weipu Database for Chinese Technical Periodicals, Wan-fang Database, and Chinese ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018512
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:This study was performed to explore the effects of probucol on contrast-induced acute kidney injury (CIAKI) in patients with coronary heart disease undergoing percutaneous coronary intervention (PCI). METHODS:In total, 220 patients undergoing PCI were randomly assigned to either the control group (hydration ...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000016049
更新日期:2019-06-01 00:00:00
abstract:RATIONALE:Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is a rare cancer belonging to the group of primary T-cell lymphoproliferative diseases. C-ALCL is characterized by the presence of single or multiple ulcerated lesions on the skin's surface. PATIENT CONCERNS:This is the case of a 73-year-old man who r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009645
更新日期:2018-01-01 00:00:00
abstract::Remifentanil and nitrous oxide (N2O) are 2 commonly used anesthetic agents. Both these agents are known risk factors for postoperative nausea and vomiting (PONV). However, remifentanil and N2O have not been directly compared in a published study. Remifentanil can induce acute tolerance or hyperalgesia, thus affecting ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005135
更新日期:2016-10-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002532.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000494756.80250.4a
更新日期:2016-08-26 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002998.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000482729.66173.0b
更新日期:2016-04-18 00:00:00