99Tcm-MDP Imaging of Osteopetrosis: Case Report.

Abstract:

:Osteopetrosis, also known as marble bone disease, is a clinically rare genetic disease, which represents a heterogeneous group of rare, inherited bone dysplasias that share the hallmark of abnormally increased bone density caused by osteoclast dysfunction. Hereby, the authors describe a case of osteopetrosis that showed increased diffuse radioactive uptake on whole body bone (99)Tc(m)-methylene diphosphonate imaging in a 56-year-old man, which increased universal radioactive uptake on craniofacial bone imaging, and enlargement of the limb long bone near the joints with evenly symmetrical enriched distribution of radioactivity. Osteopetrosis was made which based on these features and characteristics shown on (99)Tc(m)-MDP imaging.Skeletal scintigraphy with Tc-methylene diphosphonate imaging is helpful to the diagnosis of osteopetrosis. There is a characteristic of osteopetrosis different from other bone metabolic diseases.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Zheng LC,OuYang XL,Liu GC,Zhang WJ,Zhang XM

doi

10.1097/MD.0000000000000929

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

e929

issue

22

eissn

0025-7974

issn

1536-5964

pii

00005792-201506010-00017

journal_volume

94

pub_type

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