Abstract:
:Osteopetrosis, also known as marble bone disease, is a clinically rare genetic disease, which represents a heterogeneous group of rare, inherited bone dysplasias that share the hallmark of abnormally increased bone density caused by osteoclast dysfunction. Hereby, the authors describe a case of osteopetrosis that showed increased diffuse radioactive uptake on whole body bone (99)Tc(m)-methylene diphosphonate imaging in a 56-year-old man, which increased universal radioactive uptake on craniofacial bone imaging, and enlargement of the limb long bone near the joints with evenly symmetrical enriched distribution of radioactivity. Osteopetrosis was made which based on these features and characteristics shown on (99)Tc(m)-MDP imaging.Skeletal scintigraphy with Tc-methylene diphosphonate imaging is helpful to the diagnosis of osteopetrosis. There is a characteristic of osteopetrosis different from other bone metabolic diseases.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zheng LC,OuYang XL,Liu GC,Zhang WJ,Zhang XMdoi
10.1097/MD.0000000000000929subject
Has Abstractpub_date
2015-06-01 00:00:00pages
e929issue
22eissn
0025-7974issn
1536-5964pii
00005792-201506010-00017journal_volume
94pub_type
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