Abstract:
INTRODUCTION:To date, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been rarely reported for knee osteoarthritis (KOA) rehabilitation. The purpose of this case study was to setup the clinical protocol example for AlterG intervention on KOA and evaluate treatment effectiveness by 3D gait analysis combined with free EMG to explore the kinematic gait parameter changes. PATIENT CONCERNS:A 65-year-old female patient (BMI = 26, mild obesity) undergoing "more than 7 years of KOA." The activity of the right knee joint was obviously limited and she suffered from severe pain over the past month. DIAGNOSIS:Due to the patient's symptoms and radiographic findings, she was diagnosed with acute attack of KOA. INTERVENTIONS:The patient has performed clinical function evaluation and gait analysis combined at pretreatment, post-treatment, and 4 months follow-up assessment. AlterG training was performed 6 days/week for 2 weeks, with up to 30 min of training per session. The training protocol included two major parts, walking and squatting in AlterG. OUTCOMES:After 2 weeks of AlterG intervention, the 10-m walking test (10 MWT) and Timed-up-and-go (TUG) test improved significantly post-treatment, whereas the Visual Analog Scale (VAS) score decreased post-treatment. The Modified Barthel Index improved post-treatment and the patient restored basic community walk after treatment. The temporal parameter results showed that stride length (%height), mean velocity (%height), and cadence gradually increased before treatment, after treatment, and at 4-month follow-up. The right range of motion (ROM) of knee flexion-extension were gradually increased. Meanwhile, the synchronized EMG data showed that the RMS (root means square) values of the rectus femoris, semitendinosus, and biceps femoris at post-treatment were improved to different degrees than at pretreatment. CONCLUSION:We found that for this patient with KOA, AlterG relieved pain, and was also effective at improving spatio-temporal parameters, knee flexion/extension gait pattern, and corresponding muscle strength, thereby restoring certain community activities.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Liang J,Lang S,Zheng Y,Wang Y,Chen H,Yang J,Luo Z,Lin Q,Ou Hdoi
10.1097/MD.0000000000015386subject
Has Abstractpub_date
2019-05-01 00:00:00pages
e15386issue
18eissn
0025-7974issn
1536-5964pii
00005792-201905030-00035journal_volume
98pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Cisplatin monotherapy-induced cardiotoxicity is rare, and the prevalence remains unknown. It's extremely important to stop cisplatin when cardiotoxicity is considered. PATIENT CONCERNS:A 53-year-old woman developed cervical cancer. She was administered cisplatin (37 mg/m/wk) for 3 weeks, but the left ventric...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000013807
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Early postoperative complications graded according to the Clavien-Dindo classification system have not previously been correlated with long-term quality of life outcomes in patients who have had restorative proctocolectomy with ileal pouch-anal anastomosis. This study aimed to assess the severity of early ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003966
更新日期:2016-07-01 00:00:00
abstract::The purpose of this study was to assess whether breast cancer subtype (BCS) as determined by estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 can predict the axillary lymph node metastasis in breast cancer. Patients who received breast conserving surgery or mastectomy and axillary...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000002213
更新日期:2015-12-01 00:00:00
abstract::The objective of this study was to evaluate the association between falls and obesity using Asian body mass index (BMI) classifications. Using the data from the Korean community health survey in 2011, a total of 229,226 participants ranging from 19 to 106 years old were included in this study. The BMI groups were clas...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003130
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Pulmonary sequestration (PS) presenting with elevated serum tumor markers is rare, and it might be misdiagnosed as malignancy. PATIENT CONCERNS:A 26-year-old asymptomatic male patient was admitted because the x-ray showed an intrathoracic lesion. Meanwhile, the serum neuron-specific enolase (NSE) was elevate...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000022574
更新日期:2020-10-02 00:00:00
abstract:BACKGROUND:The Pharmaceutical industry sponsorship, research outcome and quality has been already evaluated for clinical trials in order to analyze if this kind of sponsorship affects the results of clinical trials. In this sense, this study has the aim to investigate whether placebo use allows positive outcomes regard...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022915
更新日期:2020-10-30 00:00:00
abstract:ABSTRACT:Lactic acidosis is one of the most fatal adverse effects of linezolid, an antibiotic used to treat serious infections caused by antibiotic-resistant bacteria. However, the measures to prevent lactic acidosis have not been well established.We performed a retrospective study to analyze the impact of applying a s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023790
更新日期:2021-01-08 00:00:00
abstract::HIV-infected individuals on antiretroviral therapy (ART) are at increased risk of cardiovascular disease (CVD). Given the relationship between innate immune activation and CVD, we investigated the association of single-nucleotide polymorphisms (SNPs) in TLR4 and CD14 and carotid intima-media thickness (cIMT), a surrog...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004477
更新日期:2016-08-01 00:00:00
abstract::Few studies in China have focused on direct expenditures for cardiovascular diseases (CVDs), making cost trends for CVDs uncertain. Epidemic modeling and forecasting may be essential for health workers and policy makers to reduce the cost burden of CVDs.To develop a time series model using Box-Jenkins methodology for ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000837
更新日期:2015-05-01 00:00:00
abstract::Thyrotoxic periodic paralysis (TPP) is characterized by the presence of muscle paralysis, hypokalemia, and hyperthyroidism. We report the case of a young man with paralysis of the lower extremities, severe hypokalemia, and concurrent hyperthyroidism. TPP was suspected; therefore, treatment consisting of judicious pota...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001689
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Recently, many kinds of cages for cervical fusion have been developed to avoid the related complications caused by tricortical iliac crest graft. The existing literature has reported the excellent clinical efficacy and superior fusion rate. However, various types of cages have their own disadvantages. Which ...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000017935
更新日期:2019-11-01 00:00:00
abstract::The current methods of monitoring the activity of lupus nephritis (LN) may cause unnecessary hospital visits or delayed immunosuppressive therapy. We aimed to find a urinary biomarker that could be developed as a home-based test for monitoring the activity of LN.Urine samples were collected immediately before a renal ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011287
更新日期:2018-06-01 00:00:00
abstract::Early risk stratification is crucial for appropriate management using invasive strategies in non-ST elevation myocardial infarction (NSTEMI), and electrocardiography (ECG) has been widely used for risk stratification. However, ECG findings in NSTEMI vary, and there is a need to define the clinical characteristics and ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004862
更新日期:2016-09-01 00:00:00
abstract::Gallbladder (GB) bleeding is very rare and it is caused by cystic artery aneurysm and rupture, or GB wall rupture. For GB rupture, the typical findings are positive Murphy's sign and jaundice. GB bleeding mostly presented as hemobilia. This is the first case presented with severe GI bleeding because of GB rupture-rela...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003870
更新日期:2016-06-01 00:00:00
abstract:RATIONALE:Football players are at high risk for lower extremity injuries because they turn on an axis of rotation, turn while decelerating, and repeatedly jump and land. One of the most common sites of injury is the knee. PATIENT CONCERNS:A 25-year-old amateur university football player with pain in the knee medial ar...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010973
更新日期:2018-06-01 00:00:00
abstract:RATIONALE:Phlegmonous gastritis is a rare bacterial infection of the gastric wall with high mortality. However, diagnosis of phlegmonous gastritis is difficult and standard treatment remains unestablished. PATIENT CONCERNS:We report a 33-year-old male patient with mixed-phenotype acute leukemia who developed acute phl...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017777
更新日期:2019-11-01 00:00:00
abstract::Xiakemycin A (XKA), a new antibiotic in the pyranonaphthoquinone family, shows antitumor activity. However, the type of cell death induced by XKA remains elusive. In this study, we aim to investigate the type of death induced by XKA in hepatic cancer.The apoptotic features, such as chromatic agglutination, reactive ox...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019848
更新日期:2020-04-01 00:00:00
abstract:RATIONALE:Tyrosine kinase inhibitors (TKIs) are known to have greater efficacy in epidermal growth factor receptor (EGFR) mutation nonsmall cell lung cancer (NSCLC). However, about 10% of EGFR wild-type (wt) patients respond to TKIs. PATIENT CONCERNS:Several strategies to increase the efficacy of TKIs in wt NSCLC are ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007732
更新日期:2017-08-01 00:00:00
abstract::The porphyrias are a group of rare metabolic disorders. The incidence and prevalence are low because the acute intermittent porphyria (AIP) is rare. Our aim was to assess the use of anthropometric and quality-of-life parameters in porphyric patients in order to identify predictor factors that might help in characteriz...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001023
更新日期:2015-07-01 00:00:00
abstract:RATIONALE:Placental site trophoblastic tumor (PSTT) is a very rare malignant tumor, belonging to a family of pregnancy-related illnesses, called gestational trophoblastic diseases (GTD). Less than 300 cases of PSTT have been reported in literature, with an incidence of ≈ 1/50,000-100,000 pregnancies representing only 0...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013439
更新日期:2018-11-01 00:00:00
abstract::The clinical and radiological characteristics of 217 consecutive episodes of gram-negative bacillary pneumonia occurring in 189 adult cancer patients between November 1968 and December 1974 were analyzed. The majority of patients had acute leukemia (54%). Fever larger than or equal to 101 degrees F was the single mos...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-197705000-00005
更新日期:1977-05-01 00:00:00
abstract::To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005017
更新日期:2016-09-01 00:00:00
abstract::Deep sternal wound infection is a severe complication after open heart surgery. According to the different severity and dimensions of the deep sternal wound infection, the treatment method is different. In this study, we aimed to describe our experience with the rectus abdominis myocutaneous flap for large sternal wou...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006391
更新日期:2017-04-01 00:00:00
abstract::Community-acquired pneumonia (CAP) is a common infectious disease in children. Rational drug use (RDU) is an important approach to reducing the disease burden and mortality rate of CAP in children. There are no monitoring indicators for assessing RDU in children. This study aimed to develop a set of indicators to asse...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009308
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND AIM:Several studies have identified that obesity and being overweight can increase the risk of developing myocardial infarction (MI). However, the predictive value of the central obesity index, that is, the waist-hip ratio (WHR), regarding MI risk remains unclear. This study aimed to provide a systematic...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000011639
更新日期:2018-07-01 00:00:00
abstract::This study aimed to assess the associations of human leukocyte antigen (HLA)-DR and interleukin (IL)-18 gene polymorphisms with hepatitis B virus (HBV).Clinical data were retrospectively reviewed between December 2006 and December 2015 at Xiangyang Central Hospital. HBV patients were assigned to the high and low viral...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011249
更新日期:2018-07-01 00:00:00
abstract::Fetuin-A is a protein with various biological functions. It plays a role in insulin resistance and arterial calcium deposition. Thyroid dysfunction may affect energy expenditure, glucose metabolism, and the risk of cardiovascular diseases. In the present study, we compared the serum fetuin-A concentrations in hyperthy...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013254
更新日期:2018-11-01 00:00:00
abstract:ABSTRACT:Hepatic neuroendocrine tumors (HNETs) are uncommon neoplasms that can be subdivided into 2 types: primary and metastatic HNETs. Due to its rarity, heterogeneity and complexity, the diagnosis, treatment modalities and prognosis are still controversial.This retrospective study reviewed the effects of tumor origi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023655
更新日期:2020-12-18 00:00:00
abstract::Coronary artery disease (CAD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Patients with CKD who undergo percutaneous coronary intervention (PCI) may have more ischemic events than patients without CKD. The aim of our study was to determine the incidence of periprocedural myocardial...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005381
更新日期:2016-11-01 00:00:00
abstract:INTRODUCTION:Pulmonary sequestration (PS) is a rare pulmonary congenital malformation characterized by disconnection with the tracheobronchial tree or the pulmonary arterial blood supply thus impeding the connection to the arterial blood supply from systemic circulation, ultimately resulting in a non-functional lung. ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020052
更新日期:2020-05-01 00:00:00