Mild encephalopathy with a reversible splenial lesion mimicking transient ischemic attack: A case report.

Abstract:

BACKGROUND:Reversible splenial lesion syndrome (RESLES) is a newly recognized syndrome, and a reversible progress associated with transiently reduced diffusion lesion in the splenium of the corpus callosum (SCC) is the typical pathological finding. The routine clinical symptoms include mildly altered states of consciousness, delirium, and seizures. METHODS:We presented a 14-year-old patient with signs suggestive of transient ischemic attack (TIA), including triple episodic weakness on the right upper limb, slurred speech, and bucking, lasting several hours in each time 2 days ago. She just had a slight cold 2 weeks ago. RESULTS:No evidence of abnormality was found in laboratory examinations except an elevated percentage of lymphocyte. Magnetic resonance imaging revealed lesions in splenium of the corpus callosum and frontal-parietal subcortex on both cerebral hemispheres. Cerebrovascular examination was also unremarkable. The patient recovered to baseline within 25 hours. No treatment was given to her in hospital. In addition, the follow-up brain magnetic resonance imaging scan showed reduced lesions. TIA-like symptoms did not occur during a 30-day follow-up period. CONCLUSION:This young patient with RESLES type II exhibited TIA-like symptoms, which was not previously reported in literature. This case extends the recognized clinical phenotypes for this disorder.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Dong K,Zhang Q,Ding J,Ren L,Zhang Z,Wu L,Feng W,Song H

doi

10.1097/MD.0000000000005258

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

e5258

issue

44

eissn

0025-7974

issn

1536-5964

pii

00005792-201611010-00055

journal_volume

95

pub_type

杂志文章

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