Variation in the susceptibility of BHK populations and cloned cell lines to three strains of foot-and-mouth disease virus.

Abstract:

:BHK monolayer and suspension cell populations maintained in different laboratories were found to vary in their susceptibility to infection with three strains of foot-and-mouth disease virus (FMDV). The susceptibility of parent cell populations was compared with that of individual clones of cells derived from them. The populations tested in this way consisted of a number of cell types, each expressing a different capacity to produce FMDV. The relative numbers of susceptible and insusceptible cells in each population appeared to determine the overall susceptibility of that population. The ability of the FMDV strain Asia 1 Iran 1/73 to multiply was an indicator of the general FMDV susceptibility of a BHK cell population.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Clarke JB,Spier RE

doi

10.1007/BF01320756

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

1-9

issue

1

eissn

0304-8608

issn

1432-8798

journal_volume

63

pub_type

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