Probable role of reverse transcription in learning: correlation between hippocampal RNA-dependent DNA synthesis and learning ability in rats.

abstract：:The recent discovery that subsets of rat taste receptor cells (TRCs) express the peptide cholecystokinin (CCK) and that subsets of TRCs respond to CCK with altered potassium currents or elevated intracellular calcium via CCK-A receptor has lead to the hypothesis that CCK may play a novel signaling role within the tast...

journal_title：Neuroscience letters

authors： Lu SG,Zhao FL,Herness S

更新日期：2003-11-20 00:00:00

abstract：:The acute reactions of vasoactive intestinal polypeptide (VIP)-containing neurons in the myenteric plexus of the rat jejunum in response to circumferential clamping or transection/reanastomosis were evaluated in a detailed time course of up to ten days. Whereas in sham-operated controls VIP immunostaining was confined...

journal_title：Neuroscience letters

authors： Trudrung P,Waldner H,Sklarek J,Nitsch C

更新日期：1990-02-16 00:00:00

abstract：:Interaction of beta-adrenergic and somatostatinergic systems in the hippocampus has not been investigated fully. We studied the influence of DL-isoproterenol (ISO), a beta-adrenergic agonist and DL-propranolol (PRO), a beta-adrenergic blocking agent, on the somatostatinergic system in the rat hippocampus. The short-(5...

journal_title：Neuroscience letters

authors： López-Sañudo S,Arilla E

更新日期：1994-01-03 00:00:00

abstract：:Intracellular recordings were used to study the contribution of nicotinic and P2X receptors to synaptic transmission to morphologically identified myenteric neurons of guinea-pig ileum. Hexamethonium (100 microM) abolished fast excitatory synaptic potentials (EPSPs) in all orally projecting neurons, but fast EPSPs in ...

journal_title：Neuroscience letters

authors： Johnson PJ,Shum OR,Thornton PD,Bornstein JC

更新日期：1999-05-14 00:00:00

abstract：:The transcription factors AP-2alpha and AP-2beta are implicated to play an important role during embryonic development of different parts of the brain, and in targeted regulation of gene expression in the adult brain. Several monoaminergic genes have binding sites for AP-2 in regulatory regions. We have in the present...

journal_title：Neuroscience letters

authors： Damberg M,Eller M,Tõnissaar M,Oreland L,Harro J

更新日期：2001-11-02 00:00:00

abstract：:A calcium-dependent potassium channel K(Ca) has been isolated in mouse motoneurons. With physiological concentrations of potassium across inside-out patches, a 100 pS K(Ca) channel was activated when the bath solution of Ca2+ was in excess of 1 microM. Introduction of the drug tedisamil, a blocker of repolarizing pota...

journal_title：Neuroscience letters

authors： McLarnon JG,Sawyer D,Michikawa M,Kim SU

更新日期：1992-09-14 00:00:00

abstract：:An antiserum to choline acetyltransferase, partially purified from bovine brain (anti-ChAT 1), when incubated with synaptosomes prepared from rat cerebral cortex in the presence of complement caused release of 10% of lactate dehydrogenase and 27% of ChAT. Sodium-dependent uptake of choline was totally abolished. Simil...

journal_title：Neuroscience letters

authors： Docherty M,Bradford HF

更新日期：1986-10-08 00:00:00

abstract：:The effect of the spectral tone structure on pre-attentive and attentive pitch discrimination was investigated. The mismatch negativity (MMN) component was recorded from reading subjects to pitch changes of identical magnitude in pure tones with only one sinusoidal frequency component and in spectrally rich tones with...

journal_title：Neuroscience letters

authors： Tervaniemi M,Ilvonen T,Sinkkonen J,Kujala A,Alho K,Huotilainen M,Näätänen R

更新日期：2000-01-21 00:00:00

abstract：:To investigate a possible role of the lateral premotor cortex in human cognitive processes, we compared brain activity during mental-operation numeral (MO-numeral) and verbal rehearsal (VR) tasks, using block-design functional MRI. Sixteen healthy subjects serially added a series of single-digit numbers during the MO-...

journal_title：Neuroscience letters

authors： Hanakawa T,Honda M,Okada T,Fukuyama H,Shibasaki H

更新日期：2003-08-28 00:00:00

abstract：:The projection of tooth pulp afferents in the spinal trigeminal nucleus (N.V.sp.) and the effect of dorsolateral medullotomy on cortical potentials evoked by electrical stimulation of Adelta tooth pulp nerve fibres were studied in cats. It was confirmed that antidromic responses were recorded in the tooth pulp nerve t...

journal_title：Neuroscience letters

authors： Keller O,Kalina M,Ujec E,Zivný A,Vyklický L

更新日期：1981-09-25 00:00:00

abstract：:Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are chemogenetic tools commonly-used to manipulate brain activity. The most widely-used synthetic DREADD ligand, clozapine-N-oxide (CNO), is back-metabolized to clozapine which can itself activate endogenous receptors. Studies in non-DREADD-expressin...

journal_title：Neuroscience letters

authors： Tran FH,Spears SL,Ahn KJ,Eisch AJ,Yun S

更新日期：2020-11-20 00:00:00

abstract：:Systemic administration of S18986, a positive allosteric modulator of AMPA receptors, improves cognition. The present study further characterizes the drug's memory-enhancing properties and is the first to investigate its intracerebral effects on learning and memory. The results showed that rats receiving a single dose...

journal_title：Neuroscience letters

authors： Yefimenko N,Portero-Tresserra M,Martí-Nicolovius M,Guillazo-Blanch G,Vale-Martínez A

更新日期：2013-08-26 00:00:00

abstract：:Although first mentions about calcium disturbances in psychiatric diseases appeared more than 30 years ago, the most recent genomic and proteomic findings confirmed a significant role of Ca2+ and Ca2+-regulated pathways in development of neuropathological processes, including bipolar disorder and schizophrenia. Moreov...

journal_title：Neuroscience letters

authors： Lisek M,Boczek T,Zylinska L

更新日期：2018-01-10 00:00:00

abstract：:We report positron emission tomographic measurements of regional cerebral blood flow (rCBF) in a male patient with war and torture related post-traumatic stress disorder (PTSD) during symptom provocation. The subject was exposed to war related sounds before and after treatment with a selective serotonin reuptake inhib...

journal_title：Neuroscience letters

authors： Fernandez M,Pissiota A,Frans O,von Knorring L,Fischer H,Fredrikson M

更新日期：2001-01-12 00:00:00

abstract：:It is well known that spinal glia plays a key role in the pathogenesis of pain. The present study was designed to determine the roles of spinal microglia in bee venom-induced persistent spontaneous nociception (PSN), mechanical hyperalgesia and inflammation. We determined the effects of microglia inhibitor minocycline...

journal_title：Neuroscience letters

authors： Chen HS,Wang JX,Zhang JH,Li FP,Qu F,Liu BJ,Li M,Lu Y

更新日期：2013-02-08 00:00:00

abstract：:Antisera raised against 3 unrelated synthetic neuropeptides - salmon melanin-concentrating hormone, human growth hormone-releasing factor1-37, and alpha-melanotropin - stained the same extensive neuron population in lateral and dorsal areas of the posterior hypothalamus. Controls for specificity have shown that these ...

journal_title：Neuroscience letters

authors： Fellmann D,Bugnon C,Risold PY

更新日期：1987-03-09 00:00:00

abstract：:Recently, researchers have developed protocols for human cerebral organoids using human pluripotent stem cells, which mimic the structure of the developing human brain. Existing research demonstrated that human cerebral organoids which undergo short cultivation periods, contain astrocytes, neurons, and neural stem cel...

journal_title：Neuroscience letters

authors： Matsui TK,Matsubayashi M,Sakaguchi YM,Hayashi RK,Zheng C,Sugie K,Hasegawa M,Nakagawa T,Mori E

更新日期：2018-03-23 00:00:00

abstract：:Recently, a mitogen activated protein kinase has been implicated in the generation of a phosphorylated paired helical filament (PHF) epitope recognized by the monoclonal antibody AT8. This epitope consists of phosphorylated serines 199 and/or 202 of the human microtubule associated protein tau. Theoretically, aside fr...

journal_title：Neuroscience letters

authors： Vandermeeren M,Lübke U,Six J,Cras P

更新日期：1993-04-16 00:00:00

abstract：:Oxygen tension is critical for proliferation of human and murine midbrain-derived neural precursor cells (mNPCs). Lack of hypoxia-inducible factor-1α (HIF1α) impairs midbrain dopaminergic neurogenesis which could be rescued by vascular endothelial growth factor (VEGF) via VEGFR-2 signaling. Here, we conditionally inac...

journal_title：Neuroscience letters

authors： Hermann A,Loewenbrück KF,Boldt Ä,Fiedler C,Maisel M,Kalucka J,Schwarz J,Breier G,Storch A

更新日期：2013-10-11 00:00:00

abstract：:Current-voltage (I-V) relationships of glutamate receptors activated by the non-NMDA receptor agonist, kainate (KA), were determined in Xenopus laevis oocytes injected with either calf or chick brain mRNA. In most injected oocytes (n = 44; 84%), I-V plots to 80 microM KA exhibited inward rectification; however, in som...

journal_title：Neuroscience letters

authors： Bowie D,Smart TG

更新日期：1993-03-05 00:00:00

abstract：:Pannexins form single membrane channels that regulate the passage of ions, small molecules and metabolites between the intra- and extracellular compartments. In the central nervous system, these channels are integrated into numerous signaling cascades that shape brain physiology and pathology. Post-translational modif...

journal_title：Neuroscience letters

authors： Lohman AW,Weilinger NL,Santos SM,Bialecki J,Werner AC,Anderson CL,Thompson RJ

更新日期：2019-03-16 00:00:00

abstract：:Changes in cytokine and chemokine expression during Wallerian degeneration have been studied using nerve transection models, which result in denervation of both myelinating and non-myelinating Schwann cells. Cytokine and chemokine response of non-myelinating Remak Schwann cells to loss of their axons is unknown. In th...

journal_title：Neuroscience letters

authors： Cheepudomwit T,Güzelsu E,Zhou C,Griffin JW,Höke A

更新日期：2008-01-17 00:00:00

abstract：:Alzheimer's Disease (AD) is a neurodegenerative disorder with a complex aetiology displayed by multiple pathogenic factors. The APOE varepsilon4 allele represents the only established genetic risk factor for sporadic AD; in addition, previous findings on three single nucleotide polymorphisms (SNPs) located on the APOE...

journal_title：Neuroscience letters

authors： Valenza A,Bizzarro A,Marra C,Lauria A,Guglielmi V,Rossi C,Tiziano FD,Brahe C,Masullo C

更新日期：2010-03-26 00:00:00

abstract：:It is known that mice homozygous for the retinal degeneration (rd) mutation are able to synchronize their circadian rhythms to light-dark cycles. In the present experiments mice were given a choice of a dark or an illuminated living and nesting area. C3H, CBA and C57 rd/rd mice spent more time in the dark than in the ...

journal_title：Neuroscience letters

authors： Mrosovsky N,Hampton RR

更新日期：1997-02-07 00:00:00

abstract：:Central diabetes insipidus can occur after hypothalamic-hypophyseal tract injury. This injury is linked with a deficit in circulating vasopressin and oxytocin, which are produced in the supraoptic nuclei and the hypothalamic paraventricular nuclei. Previous studies indicate that an ectopic neural lobe forms after pitu...

journal_title：Neuroscience letters

authors： Feng Z,Ou Y,Zhou M,Wu G,Ma L,Zhang Y,Liu Y,Qi S

更新日期：2018-04-23 00:00:00

abstract：:The actions of vasoactive intestinal polypeptide (VIP) were investigated on superficial dorsal horn (LI-IV) neurones in longitudinal slices of the rat lumbar spinal cord in vitro. Bath application of VIP (1-2 mM) cause depolarizations which were accompanied by a lowering of the threshold for excitation of the neurone ...

journal_title：Neuroscience letters

authors： Liu XH,Morris R

更新日期：1999-11-26 00:00:00

abstract：:The purpose of this study was to clarify the effect of Chinese propolis on the expression level of neurotrophic factors in dental pulp cells (DPCs). We also investigated that the effects of the conditioned medium (CM) of DPCs stimulated by the propolis against oxidative and endoplasmic reticulum (ER) stresses in human...

journal_title：Neuroscience letters

authors： Kudo D,Inden M,Sekine S,Tamaoki N,Iida K,Naito E,Watanabe K,Kamishina H,Shibata T,Hozumi I

更新日期：2015-03-04 00:00:00

abstract：:The effects of aging on sex differences in analgesia from the kappa-opioid agonist, U50,488H (U50), were examined in C57BL/6J mice. U50 analgesia can be blocked by the N-methyl-d-aspartate receptor antagonist, MK-801 (MK), in male rodents and gonadectomized females, but not hormonally intact or estrogen-replaced femal...

journal_title：Neuroscience letters

authors： Sternberg WF,Ritchie J,Mogil JS

更新日期：2004-06-10 00:00:00

abstract：:In 8 subjects the spontaneous termination of sleep was determined after repetitive exposure to either bright or dim light, between 6.00 and 9.00 h, on 3 days preceding sleep assessment. Sleep duration was significantly shorter following bright light than following dim light. During sleep the time course of EEG energy ...

journal_title：Neuroscience letters

authors： Dijk DJ,Visscher CA,Bloem GM,Beersma DG,Daan S

更新日期：1987-01-14 00:00:00

abstract：:Effects of intracellularly applied L-arginine and nicotinamide adenine dinucleotide phosphate (NADPH) on the dark voltage and light responses of retinal rods were studied by means of the whole-cell patch-clamp technique. In this mode an exchange of substances by diffusion between cytosol and pipette medium occurs (Pfl...

journal_title：Neuroscience letters

authors： Tsuyama Y,Nöll GN,Schmidt KF

更新日期：1993-01-04 00:00:00