Abstract:
:The uptake of tritiated gamma-aminobutyric acid (3H-GABA) in the oculomotor nucleus of the cat was studied, using light and electron microscopic examination of radioautograms after intracerebral in vivo administration of the amino-acid. A glial uptake by oligodendrocytes was seen together with a neuronal uptake of the tracer in a certain type of axon terminals found in synaptic contact with both dendrites and soma, some of them exhibiting all the ultrastructural features of motoneurons. Previous neurochemical, electrophysiological and immunocytochemical studies indicate that GABA might well be the inhibitory neurotransmitter in the vestibuloocular reflex arc. The present results show that a morphological substrate exists for the presumed postsynaptic GABAergic inhibition of ocular motoneurons, at least in the oculomotor nucleus of the cat.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Lanoir J,Soghomonian JJ,Cadenel Gdoi
10.1007/BF00239581subject
Has Abstractpub_date
1982-01-01 00:00:00pages
137-43issue
1eissn
0014-4819issn
1432-1106journal_volume
48pub_type
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