Abstract:
:We have previously established an fMRI task battery suitable for mapping the language processing network in children. Among the tasks used, the synonyms and the vowel identification task induced robust task-related activations in children with average language abilities; however, the fixed presentation time seems to be a drawback in participants with above- or below-average language abilities. This feasibility study in healthy adults (n = 20) was aimed at adapting these tasks to the individual level of each patient by implementing a self-paced stimulus presentation. The impact of using a block- versus an event-related statistical approach was also evaluated. The self-paced modification allowed our participants with above-average language abilities to process stimuli much faster than originally implemented, likely increasing task adherence. A higher specificity of the event-related analysis was confirmed by stronger left inferior frontal and crossed cerebellar activations. We suggest that self-paced paradigms and event-related analyses may both increase specificity and applicability.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Máté A,Lidzba K,Hauser TK,Staudt M,Wilke Mdoi
10.1007/s00221-015-4473-8subject
Has Abstractpub_date
2016-03-01 00:00:00pages
673-84issue
3eissn
0014-4819issn
1432-1106pii
10.1007/s00221-015-4473-8journal_volume
234pub_type
杂志文章abstract::Single-neuron activities were recorded in the hindlimb region of the primary somatosensory cortex and part of area 5 in awake Japanese monkeys. A total of 1050 units were isolated from five hemispheres of four animals. Receptive fields (RFs) and submodalities were identified for 90% of isolated neurons in areas 3a and...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000464
更新日期:2000-09-01 00:00:00
abstract::The parameters characterizing Listing's plane have been determined in a group of normal subjects, and in patients who have had unilateral vestibular deafferentation on the right or left side. All patients were well compensated. There was no statistically significant difference in the orientation of Listing's plane bet...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00227346
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abstract::In order to relate single cell performance to behavioral discrimination one needs measurements of the response variance of the units. We recorded from 183 single units of area V1 of monkeys performing an orientation discrimination task. The response variance was found to increase with increasing response strength. Thi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00275002
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abstract::An experiment was performed to characterise the movement kinematics and the electromyogram (EMG) during rhythmic voluntary flexion and extension of the wrist against different compliant (elastic-viscous-inertial) loads. Three levels of each type of load, and an unloaded condition, were employed. The movements were pac...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-001-0946-z
更新日期:2002-02-01 00:00:00
abstract::We investigated whether the control of movement of the left hand is more likely to involve the use of allocentric information than movements performed with the right hand. Previous studies (Gonzalez et al. in J Neurophys 95:3496-3501, 2006; De Grave et al. in Exp Br Res 193:421-427, 2009) have reported contradictory f...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3007-x
更新日期:2012-04-01 00:00:00
abstract::Modern tools in technological environments are often characterized by a spatial separation of hand actions (operating a remote control) and their intended action effects (displayed movements of an unmanned vehicle, a robot, or an avatar on a screen). Often non-corresponding proximal and distal movement effects put hig...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3018-7
更新日期:2012-04-01 00:00:00
abstract::Through an experimental study of the stability properties of the human neuromuscular system while it performs simple point-to-point arm movements, this paper evaluates the concepts of equilibrium and virtual trajectories as a means of executing movement of the arm. Human subjects grasped the instrumented handle of a t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228024
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abstract::Recent studies have demonstrated that dyslexia is associated with deficits in the temporal encoding of sensory information. While most previous studies have focused on information processing within a single sensory modality, it is clear that the deficits seen in dyslexia span multiple sensory systems. Surprisingly, al...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-005-2387-6
更新日期:2005-10-01 00:00:00
abstract::Developmental changes in the human brain coincide with and underlie changes in a wide range of motor and cognitive abilities. Neuroimaging studies have shown that musical training can result in structural and functional plasticity in the brains of musicians, and that this plasticity is greater for those who begin trai...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0619-z
更新日期:2007-01-01 00:00:00
abstract::By studying human movement in the laboratory, a number of regularities and invariants such as planarity and the principle of isochrony have been discovered. The theoretical idea has gained traction that movement may be generated from a limited set of movement primitives that would encode these invariants. In this stud...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3205-6
更新日期:2012-10-01 00:00:00
abstract::Previous studies have shown that rearing rabbits in a stroboscopically illuminated environment results in a decrease in orientation and direction selectivity and an increase in responsivity to stroboscopic stimuli among neurons in area 17. In the present study, the critical period for susceptibility to these effects w...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239202
更新日期:1983-01-01 00:00:00
abstract::The remote distractor effect is a robust finding whereby a saccade to a lateralised visual target is delayed by the simultaneous, or near simultaneous, onset of a distractor in the opposite hemifield. Saccadic inhibition is a more recently discovered phenomenon whereby a transient change to the scene during a visual t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1558-7
更新日期:2008-10-01 00:00:00
abstract::Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3026-7
更新日期:2012-05-01 00:00:00
abstract::The purpose of this study was to compare the asymmetric gait induced by unilateral spinal cord injury in chicks with asymmetric gaits of other bipeds and quadrupeds. After lateral hemisection of the left thoracic spinal cord, kinetic (ground reaction forces) and kinematic (distance and timing) data were recorded as ch...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050515
更新日期:1998-10-01 00:00:00
abstract::When asked to identify the position of a sound, listeners can report its perceived location as well as their subjective certainty about this spatial judgement. Yet, research to date focused primarily on measures of perceived location (e.g., accuracy and precision of pointing responses), neglecting instead the phenomen...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05748-4
更新日期:2020-03-01 00:00:00
abstract::Retinal and cortical afferents to the superior colliculus of the rabbit were labelled simultaneously by injecting 3H-leucine into the right eye and HRP into the left visual cortex. It could be shown that there is some convergence of retinal and cortical input onto common postsynaptic elements in the superficial grey, ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00243837
更新日期:1986-01-01 00:00:00
abstract::The present study was performed to explore the antinociceptive effects of the galanin receptor 1 agonist M617 in lateral habenula complex in rats. Intra-lateral habenula injection of 0.1, 0.5, 1 or 2 nmol of galanin induced dose-dependent increases in hindpaw withdrawal latencies (HWLs) to noxious thermal and mechanic...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4480-9
更新日期:2016-02-01 00:00:00
abstract::The eyeblink reflex is one of the most extensively studied behaviors in mammals. The active downward force that causes lid closure is controlled by the orbicularis oculi (OO) muscle. To augment our studies on the neurophysiology and plasticity of the rat eyeblink circuit, here we present the first anatomical paper to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005729
更新日期:1997-08-01 00:00:00
abstract::Two experiments investigated the contribution of space- and object-based coordinates to previously reported leftward perceptual biases (pseudoneglect) at various locations across visual space. Neurologically intact participants (n = 34 and 27) made luminance discriminations between two left/right mirror-reversed lumin...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2196-3
更新日期:2005-04-01 00:00:00
abstract::We investigated the effect of spatial uncertainty on motor planning by using the cueing method in a reaching task (experiment 1). Discrete spatial cues indicated the different locations in which the target could be presented. The number of cues as well as their direction changed from trial to trial. We tested the adeq...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1453-1
更新日期:2003-06-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000337
更新日期:2000-06-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231774
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abstract::Recent evidence suggests that brain injury can impair the ability to independently activate shoulder and elbow muscles. We hypothesized that if muscle activation patterns are constrained, then brain-injured subjects should not be able to accurately grade initial hand movement direction during reaching toward a broad r...
journal_title:Experimental brain research
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更新日期:2002-04-01 00:00:00
abstract::Light touch of the index finger with a stationary surface at non-mechanically supportive force levels (<100 g) greatly attenuates the body sway of standing subjects. In three experiments, we evaluated the properties of finger contact and of the contacted object necessary to produce postural stabilization in subjects s...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210100775
更新日期:2001-08-01 00:00:00
abstract::Vision can improve bipedal upright stability during standing and locomotion. However, during locomotion, vision supports additional behaviors such as gait cycle modulation, navigation, and obstacle avoidance. Here, we investigate how the multiple roles of vision are reflected in the dynamics of trunk control as the ne...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2414-0
更新日期:2010-10-01 00:00:00
abstract::A central network of neurones in the spinal cord has been shown to produce a rhythmic motor output similar to locomotion after suppression of all afferent inflow. The experiments were performed mainly in acute spinal cats (th. 12), which had received DOPA i.v. and the monoamine oxidase inhibitor Nialamide. In some pre...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235671
更新日期:1979-01-15 00:00:00
abstract::Reflexive attentional shift in response to another individual's gaze direction has been reported, but it remains unknown whether this process can occur subliminally. We investigated this issue using facial stimuli consisting of drawings (Experiment 1) and photographs (Experiment 2). The gaze direction was expressed by...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1025-x
更新日期:2007-10-01 00:00:00
abstract::Many age-related degenerative diseases of the central nervous system (CNS) increasingly appear to have similarities in their underlying causes. By applying knowledge between disorders, and in particular between degenerative diseases of different components of the CNS (e.g. the eye and the brain), we can begin to eluci...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-014-4078-7
更新日期:2014-11-01 00:00:00
abstract::Hyper-gravity provides a unique environment to study how misperceptions impact control of orientation relative to gravity. Previous studies have found that static and dynamic roll tilts are perceptually overestimated in hyper-gravity. The current investigation quantifies how this influences control of orientation. We ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4215-y
更新日期:2015-05-01 00:00:00
abstract::We have investigated the visual responses of 184 single units located in the superficial layers of the optic tectum (OT) of the decerebrate, paralysed pigeon. Visual responses were similar to those reported in non-decerebrate preparations; most units responded best to moving visual stimuli, 18% were directionally sele...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005779
更新日期:1997-10-01 00:00:00