Abstract：
:We have previously established an fMRI task battery suitable for mapping the language processing network in children. Among the tasks used, the synonyms and the vowel identification task induced robust task-related activations in children with average language abilities; however, the fixed presentation time seems to be a drawback in participants with above- or below-average language abilities. This feasibility study in healthy adults (n = 20) was aimed at adapting these tasks to the individual level of each patient by implementing a self-paced stimulus presentation. The impact of using a block- versus an event-related statistical approach was also evaluated. The self-paced modification allowed our participants with above-average language abilities to process stimuli much faster than originally implemented, likely increasing task adherence. A higher specificity of the event-related analysis was confirmed by stronger left inferior frontal and crossed cerebellar activations. We suggest that self-paced paradigms and event-related analyses may both increase specificity and applicability.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Máté A,Lidzba K,Hauser TK,Staudt M,Wilke Mdoi
10.1007/s00221-015-4473-8subject
Has Abstractpub_date
2016-03-01 00:00:00pages
673-84issue
3eissn
0014-4819issn
1432-1106pii
10.1007/s00221-015-4473-8journal_volume
234pub_type
杂志文章abstract：:Little is known about anticipatory postural adjustments (APAs) developing when body segments of tiny mass are moved. Thus, APAs in the human upper-limb were investigated during a gentle and small index finger tap (35 mm stroke in 50 ms). This task was fulfilled by ten subjects either with prone or supine hand. EMG was...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1668-2
更新日期：2009-03-01 00:00:00
abstract：:Both human and animal research indicate that rapid eye movement sleep (REM) plays an important role in the processing of emotional information. REM is altered after fear conditioning in rats, but this alteration can be mitigated by exposure to a naïve conspecific. In addition, both the housing condition (isolated vs p...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3828-x
更新日期：2014-05-01 00:00:00
abstract：:The effects of trans-1-amino-cyclopentyl-1,3-dicarboxylate (trans-ACPD) and of DL-2-amino-3-phosphonopropionic acid (AP3), i.e. selective agonist and antagonist of metabotropic quisqualate receptors respectively, on parallel fibre (PF)-mediated EPSPs of Purkinje cells (PCs) were studied in an in vitro slice preparatio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228964
更新日期：1991-01-01 00:00:00
abstract：:It has recently been suggested that time perception and motor timing are influenced by the presence of biological movements and animacy in the visual scene. Here, we investigated the interactions among timing, speed and animacy in two experiments. In Experiment 1, observers had to press a button in synchrony with the ...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-012-3338-7
更新日期：2013-02-01 00:00:00
abstract：:We examined the coordination of multi-digit grasping forces as they developed during object grasping and lifting. Ten subjects with Parkinson's disease (PD; OFF and ON medication) and ten healthy age-matched control subjects lifted a manipulandum that measured normal forces at each digit and the manipulandum's positio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1129-3
更新日期：2008-02-01 00:00:00
abstract：:Intervention-induced neuroplastic changes within the motor or cognitive system have been shown in the human brain. While cognitive and motor brain areas are densely interconnected, it is unclear whether this interconnectivity allows for a shared susceptibility to neuroplastic changes. Using the preparation for a theor...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05933-5
更新日期：2020-12-01 00:00:00
abstract：:A green button may be the target of a movement, or it may instruct the opening of an adjacent door. In the first case, its spatial configuration serves to guide the hand, whereas in the second case its colour allows a decision between alternative courses of action. This study contrasts these two categories of visuomot...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100877
更新日期：2001-12-01 00:00:00
abstract：:Three experiments examined interactions between posture control in upright stance and a concurrent location memory task. Healthy young participants stood upright and memorized the locations of dots presented on a computer screen. In the retrieval phase, they indicated whether arrows presented on the screen would pass ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2970-y
更新日期：2012-03-01 00:00:00
abstract：:1.) Eye movements were recorded in four Java monkeys (M. fascicularis) after unilateral microinjections (1 microliter, concentration 1 micrograms/microliter) of the GABA antagonist, bicuculline, and the GABA agonist, muscimol, into oculomotor related regions of the vestibular nuclei. Eye movements were investigated in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228958
更新日期：1991-01-01 00:00:00
abstract：:A 3-day incremental protocol was conducted with the aim of adapting human subjects to make head movements comfortably during 30 RPM centrifugation. With motion sickness as a potentially limiting factor, the protocol was designed using a quantitative motion sickness model based upon the neural mismatch sensory conflict...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1415-8
更新日期：2008-08-01 00:00:00
abstract：:Aerobic exercise can enhance neuroplasticity although presently the neural mechanisms underpinning these benefits remain unclear. One possible mechanism is through effects on primary motor cortex (M1) function via down-regulation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). The aim of the present...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4767-5
更新日期：2016-12-01 00:00:00
abstract：:This purpose of this study was to examine the spatial coding of eye movements during static roll tilt (up to +/-45 degrees) relative to perceived earth and head orientations. Binocular videographic recordings obtained in darkness from eight subjects allowed us to quantify the mean deviations in gaze trajectories along...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050436
更新日期：1998-07-01 00:00:00
abstract：:We examined the characteristic features of galanin (GAL)-containing nerve afferents in the intermediolateral nucleus (IML) of the rat lumbosacral spinal cord (L6, S1), i.e., spinal parasympathetic nucleus, by immunocytochemistry at both light and electron microscopic levels. Firstly, the types of synapses formed by GA...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229624
更新日期：1996-06-01 00:00:00
abstract：:During saccadic eye movements, images of external objects move rapidly across the retina. Small, unpredictable displacements imposed upon a target moving at saccadic velocity were detected with equal accuracy when (1) the retinal image velocity was caused by an eye movement, or (2) when the same velocity was produced ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236664
更新日期：1980-01-01 00:00:00
abstract：:The activity of voltage-gated K(+) channels (Kv) can be dynamically modulated by several events, including neurotransmitter stimulated biochemical cascades mediated by G protein-coupled receptors such as 5-HT2 receptors (5-HT2Rs). Activation of 5-HT2A/CR inhibits the Shaker-like K(+) channels Kv1.1 and Kv1.2, and this...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-013-3555-8
更新日期：2013-10-01 00:00:00
abstract：:The 2-deoxyglucose (2-DG) autoradiographic technique was used to map functional activity in the central auditory system of the mongolian gerbil, throughout the period of functional onset. Uptake of 2-DG during exposure to 105 dB SPL wide band noise (WBN) was compared to silence in adults and in neonates at 12, 14, 16 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239360
更新日期：1982-01-01 00:00:00
abstract：:Auditory dysfunction, including hypersensitivity and tinnitus, is a common symptom of autism spectrum disorder (ASD). Prenatal exposure to the antiseizure medication valproic acid (VPA) significantly increases the risk of ASD in humans and similar exposure is utilized as an animal model of ASD in rodents. Animals expo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05982-w
更新日期：2020-11-16 00:00:00
abstract：:Although maintenance of steady contractions is required for many daily tasks, there is little understanding of brain areas that modulate lower limb force accuracy. Functional magnetic resonance imaging was used to determine brain areas associated with steadiness and force during static (isometric) lower limb target-ma...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3976-z
更新日期：2014-10-01 00:00:00
abstract：:The aim of the study was to investigate grip-load force regulation in Huntington's disease (HD) patients as compared to control subjects during the performance of a manipulative task that required rhythmical unimanual or bimanual isodirectional/non-isodirectional actions in the sagittal plane. Results showed that the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0992-6
更新日期：2002-04-01 00:00:00
abstract：:The cerebral representation of space depends on the integration of many different sensory inputs. The vestibular system provides one such input and its dysfunction can cause profound spatial disorientation. Using positron emission tomography (PET), we measured regional cerebral perfusion with various vestibular stimul...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00241421
更新日期：1994-01-01 00:00:00
abstract：:The evoked expression of the immediate early gene-encoded proteins c-Fos and Krox-24 was used to study activation of hindbrain neurons as a function of the development of cyclophosphamide (CP) cystitis in behaving rats. CP-injected animals received a single dose of 100 mg/kg i.p. under transient volatile anesthesia an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227263
更新日期：1996-03-01 00:00:00
abstract：:Perhaps the most intriguing disorders of body representation are those that are not due to primary disease of brain tissue. Strange and sometimes painful phantom limb sensations can result from loss of afference to the brain; and Complex Regional Pain Syndrome (CRPS)-the subject of the current report-can follow limb t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2107-8
更新日期：2010-07-01 00:00:00
abstract：:Previous findings have suggested that visuomotor programming can make use of learned size information in experimental paradigms where movement kinematics are quite consistent from trial to trial. The present experiment was designed to test whether or not this conclusion could be generalized to a different manipulation...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00221-002-1250-2
更新日期：2002-12-01 00:00:00
abstract：:In cat medial gastrocnemius motoneurons, single stimuli to the cutaneous sural nerve evoke a post-synaptic potential with a mixture of depolarization and hyperpolarization, depolarization being dominant in type F cells and hyperpolarization in type S cells. This pattern is consistent with previous reports showing that...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230025
更新日期：1992-01-01 00:00:00
abstract：:Lightly touching a stable reference is associated with sway reduction during standing. Unexpected displacement of the touch reference results in a false-positive balance reaction in some participants, but only with the first such disturbance. This study investigated whether light touch reduces standing sway (1) after ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5455-4
更新日期：2019-03-01 00:00:00
abstract：:Threshold elevation in the periphery of the visual field as a consequence of repetitive stimulation can be abolished by stimulating a mirror-symmetric position in the contralateral visual half-field. A patient suffering from a congenital malformation of the right superior colliculus did not exhibit threshold elevation...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236761
更新日期：1979-05-02 00:00:00
abstract：:Quantitative studies were made of the distribution of labeled intracortical axons after focal injections of horseradish peroxidase (HRP) into mouse barrel cortex, in vitro. The pattern of labeled fibers was compared to that of labeled cell bodies with respect to the barrel map in layer IV. We analyzed 4 cortices with ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231244
更新日期：1990-01-01 00:00:00
abstract：:The latencies of visually-evoked responses from X- and Y-type neurons of the cat's dorsal lateral geniculate nucleus were measured in a manner that takes account of the inherent variability of discharge in these cells. Latencies measured in this way vary from trial to trial in one cell (and also between cells) by tens...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235998
更新日期：1987-01-01 00:00:00
abstract：:The aim of this study was to investigate the effects of self-reinnervation of the medial (MG) and lateral gastrocnemius (LG) muscles on joint kinematics of the whole hindlimb during overground walking on surfaces of varying slope in the cat. Hindlimb kinematics were assessed (1) with little or no activity in MG and LG...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0938-8
更新日期：2007-08-01 00:00:00
abstract：:We investigated the quantitative relationship between saccadic activity (as reflected in frequency of occurrence and amplitude of saccades) and blood oxygenation level dependent (BOLD) changes in the cerebral cortex using functional magnetic resonance imaging (fMRI). Furthermore, we investigated quantitative changes i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100844
更新日期：2001-11-01 00:00:00
